{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T02:53:32Z","timestamp":1789872812462,"version":"4.0.1"},"reference-count":21,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,7,6]],"date-time":"2016-07-06T00:00:00Z","timestamp":1467763200000},"content-version":"vor","delay-in-days":1282,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jtcvsonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Thoracic and Cardiovascular Surgery"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1016\/j.jtcvs.2012.10.013","type":"journal-article","created":{"date-parts":[[2012,10,29]],"date-time":"2012-10-29T09:45:15Z","timestamp":1351503915000},"page":"83-89","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"title":["Resection and heated pleural chemoperfusion in patients with thymic\u00a0epithelial malignant disease and pleural spread: A\u00a0single-institution experience"],"prefix":"10.1016","volume":"145","author":[{"given":"Alon","family":"Yellin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Simansky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronny","family":"Ben-Avi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Perelman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nona","family":"Zeitlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yael","family":"Refaely","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alon","family":"Ben-Nun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtcvs.2012.10.013_bib1","series-title":"Pearson's thoracic & esophageal surgery","first-page":"1589","article-title":"Thymic tumors: a review of current diagnosis, classification, and treatment","author":"Detterbeck","year":"2008"},{"key":"10.1016\/j.jtcvs.2012.10.013_bib2","first-page":"894","article-title":"Single center 40-year results of redo operation for recurrent thymoma","volume":"40","author":"Margaritora","year":"2011","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.jtcvs.2012.10.013_bib3","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1510\/icvts.2010.264036","article-title":"Number of recurrent lesions is a prognostic factor in recurrent thymoma","volume":"13","author":"Yano","year":"2011","journal-title":"Interac Cardiovasc Thorac Surg"},{"key":"10.1016\/j.jtcvs.2012.10.013_bib4","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1038\/sj.bjc.6605347","article-title":"A phase II trial of dose-dense chemotherapy in patients with disseminated thymoma: report of a Japan Clinical Oncology Group trial (JCOG 9605)","volume":"101","author":"Kunitoh","year":"2009","journal-title":"Br J Cancer"},{"key":"10.1016\/j.jtcvs.2012.10.013_bib5","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.lungcan.2011.10.004","article-title":"Multimodal treatment for stage IVA thymoma: a proposable strategy","volume":"76","author":"Rena","year":"2011","journal-title":"Lung Cancer"},{"key":"10.1016\/j.jtcvs.2012.10.013_bib6","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1097\/JTO.0b013e31815e8b73","article-title":"Invasive thymoma: post operative mediastinal irradiation and low-dose entire hemithorax irradiation in patients with pleural dissemination","volume":"3","author":"Sugie","year":"2008","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.jtcvs.2012.10.013_bib7","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1510\/icvts.2010.255307","article-title":"Induction chemotherapy, cytoreductive surgery and intraoperative hyperthermic pleural irrigation in patients with stage IVA thymoma","volume":"12","author":"Belcher","year":"2011","journal-title":"Interac Cardiovasc Thorac Surg"},{"key":"10.1016\/j.jtcvs.2012.10.013_bib8","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1016\/j.jtcvs.2008.09.033","article-title":"Management of pleural recurrence after curative resection of thymoma","volume":"137","author":"Lucchi","year":"2009","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2012.10.013_bib9","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1016\/j.athoracsur.2006.05.028","article-title":"Pleuropneumonectomy for the treatment of Masaoka stage IVA thymoma","volume":"82","author":"Wright","year":"2006","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2012.10.013_bib10","doi-asserted-by":"crossref","first-page":"e133","DOI":"10.1016\/j.ejcts.2010.12.064","article-title":"Long-term outcome of pleuropneumonectomy for Masaoka stage IVa thymoma","volume":"39","author":"Fabre","year":"2011","journal-title":"Eur J Card Thorac Surg"},{"key":"10.1016\/j.jtcvs.2012.10.013_bib11","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1016\/j.jtcvs.2007.07.049","article-title":"Feasibility of multimodality therapy including extended resections in stage IVA thymoma","volume":"134","author":"Huang","year":"2007","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2012.10.013_bib12","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1016\/j.athoracsur.2009.05.019","article-title":"Multimodality therapy for patients with invasive thymoma disseminated into the pleural cavity: the potential role of extrapleural pneumonectomy","volume":"88","author":"Ishikawa","year":"2009","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2012.10.013_bib13","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1159\/000227208","article-title":"A new device for the treatment of pleural malignancies: intrapleural chemohyperthermia\u2014preliminary report","volume":"50","author":"Carry","year":"1993","journal-title":"Oncology"},{"key":"10.1016\/j.jtcvs.2012.10.013_bib14","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1200\/JCO.1994.12.6.1156","article-title":"A phase II study of pleurectomy\/decortications followed by intrapleural and systemic chemotherapy for malignant pleural mesothelioma","volume":"12","author":"Rusch","year":"1994","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jtcvs.2012.10.013_bib15","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/0003-4975(94)00614-D","article-title":"Intrapleural perfusion hyperthermo-chemotherapy for malignant pleural dissemination and effusion","volume":"59","author":"Matzuzaki","year":"1995","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2012.10.013_bib16","doi-asserted-by":"crossref","first-page":"2197","DOI":"10.1002\/1097-0142(20011015)92:8<2197::AID-CNCR1563>3.0.CO;2-F","article-title":"Hyperthermic pleural perfusion with cisplatinum: early clinical experience","volume":"92","author":"Yellin","year":"2001","journal-title":"Cancer"},{"key":"10.1016\/j.jtcvs.2012.10.013_bib17","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/S0003-4975(01)02786-2","article-title":"Resection and perfusion thermochemotherapy: a new approach for the treatment of thymic malignancies with pleural spread","volume":"72","author":"Refaely","year":"2001","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2012.10.013_bib18","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/0003-4975(91)90478-9","article-title":"Thymoma: results of 241 operated cases","volume":"51","author":"Maggi","year":"1991","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2012.10.013_bib19","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/S0003-4975(03)00555-1","article-title":"Therapy for thymic epithelial tumors: a clinical study of 1,320 patients from Japan","volume":"75","author":"Kondo","year":"2003","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2012.10.013_bib20","doi-asserted-by":"crossref","first-page":"1840","DOI":"10.1016\/j.athoracsur.2004.12.047","article-title":"Advanced stage thymoma and thymic carcinoma: results of multimodality treatment","volume":"79","author":"Lucchi","year":"2005","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2012.10.013_bib21","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.jtcvs.2009.02.046","article-title":"Extrapleural pneumonectomy followed by intracavitary intraoperative hyperthermic cisplatinum with pharmacologic cytoprotection for treatment of malignant pleural mesothelioma: a phase II prospective study","volume":"138","author":"Tilleman","year":"2009","journal-title":"J Thorac Cardiovasc Surg"}],"container-title":["The Journal of Thoracic and Cardiovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022522312012548?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022522312012548?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T16:54:07Z","timestamp":1758387247000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022522312012548"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["S0022522312012548"],"URL":"https:\/\/doi.org\/10.1016\/j.jtcvs.2012.10.013","relation":{},"ISSN":["0022-5223"],"issn-type":[{"value":"0022-5223","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Resection and heated pleural chemoperfusion in patients with thymic\u00a0epithelial malignant disease and pleural spread: A\u00a0single-institution experience","name":"articletitle","label":"Article Title"},{"value":"The Journal of Thoracic and Cardiovascular Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtcvs.2012.10.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}