{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T18:04:31Z","timestamp":1792433071029,"version":"4.5.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,7,6]],"date-time":"2016-07-06T00:00:00Z","timestamp":1467763200000},"content-version":"vor","delay-in-days":736,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jtcvsonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Thoracic and Cardiovascular Surgery"],"published-print":{"date-parts":[[2014,7]]},"DOI":"10.1016\/j.jtcvs.2013.07.079","type":"journal-article","created":{"date-parts":[[2013,9,20]],"date-time":"2013-09-20T04:21:30Z","timestamp":1379650890000},"page":"202-206","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"title":["Early postoperative systemic inflammatory response is an important determinant for adverse 2-year neurodevelopment-associated outcomes after the Norwood procedure"],"prefix":"10.1016","volume":"148","author":[{"given":"Xiaohui","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlene M.T.","family":"Robertson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyang","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andriy","family":"Cheypesh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina A.","family":"Dinu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Suppl 1","key":"10.1016\/j.jtcvs.2013.07.079_bib1","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1017\/S1047951105002398","article-title":"Current insights regarding neurological and developmental abnormalities in children and young adults with complex congenital cardiac disease","volume":"16","author":"Wernovsky","year":"2006","journal-title":"Cardiol Young"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib2","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s00246-008-9354-5","article-title":"Inflammatory response and neurodevelopmental outcome after open-heart surgery in children","volume":"30","author":"Gessler","year":"2009","journal-title":"Pediatr Cardiol"},{"issue":"12 Suppl 1","key":"10.1016\/j.jtcvs.2013.07.079_bib3","first-page":"I103","article-title":"Effects of pH management during deep hypothermic bypass on cerebral microcirculation: alpha-stat versus pH-stat","volume":"106","author":"Duebener","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib4","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1016\/j.jtcvs.2005.02.065","article-title":"Increasing duration of deep hypothermic circulatory arrest is associated with an increased incidence of postoperative electroencephalographic seizures","volume":"130","author":"Gaynor","year":"2005","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib5","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1161\/CIRCULATIONAHA.107.741579","article-title":"Two-year survival and mental and psychomotor outcomes after the Norwood procedure: an analysis of the modified Blalock-Taussig shunt and right ventricle-to-pulmonary artery shunt surgical eras","volume":"118","author":"Atallah","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib6","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1542\/peds.85.6.984","article-title":"Congenital brain anomalies associated with the hypoplastic left heart syndrome","volume":"85","author":"Glauser","year":"1990","journal-title":"Pediatrics"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib7","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0022-3476(03)00183-5","article-title":"Length of stay after heart surgery is related to cognitive outcome at 8 years","volume":"143","author":"Newburger","year":"2003","journal-title":"J Pediatr"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib8","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.jtcvs.2007.07.036","article-title":"The influence of systemic hemodynamics and oxygen transport on cerebral oxygen saturation in neonates after the Norwood procedure","volume":"135","author":"Li","year":"2008","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"Suppl 1","key":"10.1016\/j.jtcvs.2013.07.079_bib9","first-page":"S99","article-title":"Comparison of postoperative C-reactive protein between neonates after the Norwood procedure or arterial switch operation","volume":"21","author":"Yu","year":"2011","journal-title":"Cardiol Young"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib10","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1097\/00000542-200105000-00010","article-title":"Tissue injury and the inflammatory response to pediatric cardiac surgery with cardiopulmonary bypass: a descriptive study","volume":"94","author":"Chew","year":"2001","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib11","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s12192-012-0358-y","article-title":"Changes in anti-heat shock protein 27 antibody and C-reactive protein levels following cardiac surgery and their association with cardiac function in patients with cardiovascular disease","volume":"18","author":"Rahsepar","year":"2013","journal-title":"Cell Stress Chaperones"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib12","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1177\/0891988710373598","article-title":"The relationship between inflammatory markers and post stroke cognitive impairment","volume":"23","author":"Rothenburg","year":"2010","journal-title":"J Geriatr Psychiatry Neurol"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib13","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1111\/j.1399-6576.2011.02616.x","article-title":"Perioperative inflammatory response and protein S-100\u03b2 concentrations - relationship with post-operative cognitive dysfunction in elderly patients","volume":"56","author":"Li","year":"2012","journal-title":"Acta Anaesthesiol Scand"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib14","series-title":"The Bayley Scales of Infant and Toddler Development III (Bayley-III): manual","first-page":"35","author":"Bayley","year":"1993"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib15","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1111\/j.1755-618X.1987.tb00639.x","article-title":"The 1981 socioeconomic index for occupations in Canada","volume":"24","author":"Blishen","year":"1987","journal-title":"Can Rev Soc Anthropol"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib16","doi-asserted-by":"crossref","first-page":"S2347","DOI":"10.1016\/j.athoracsur.2006.02.073","article-title":"Characterizing the inflammatory response to cardiopulmonary bypass in children","volume":"81","author":"Kozik","year":"2006","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib17","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1038\/35081509","article-title":"Functional brain development in humans","volume":"2","author":"Johnson","year":"2001","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib18","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1067\/mtc.2002.121285","article-title":"Cardiac surgery with deep hypothermic circulatory arrest produces less systemic inflammatory response than low-flow cardiopulmonary bypass in newborns","volume":"123","author":"Tassani","year":"2002","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib19","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1017\/S1047951111000904","article-title":"Hyperglycaemia is negatively associated with systemic and cerebral oxygen transport in neonates after the Norwood procedure","volume":"22","author":"Zhang","year":"2012","journal-title":"Cardiol Young"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib20","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1161\/01.STR.29.2.509","article-title":"Tumor necrosis factor-alpha-induced dilatation of cerebral arterioles","volume":"29","author":"Brian","year":"1998","journal-title":"Stroke"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib21","first-page":"H1486","article-title":"Recombinant human interleukin 1 alpha dilates pial arterioles and increases cerebrospinal fluid prostanoids in piglets","volume":"259","author":"Shibata","year":"1990","journal-title":"Am J Physiol"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib22","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1203\/01.PDR.0000144819.45689.BB","article-title":"Neonatal encephalopathy: association of cytokines with MR spectroscopy and outcome","volume":"56","author":"Bartha","year":"2004","journal-title":"Pediatr Res"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib23","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1161\/01.CIR.102.18.2165","article-title":"Direct proinflammatory effect of C-reactive protein on human endothelial cells","volume":"102","author":"Pasceri","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib24","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1161\/01.CIR.100.25.2499","article-title":"Pharmacology and biological efficacy of recombinant, humanized, single-chain antibody C5 complement inhibitor in patients undergoing coronary artery bypass graft surgery with cardiopulmonary bypass","volume":"100","author":"Fitch","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.jtcvs.2013.07.079_bib25","first-page":"A14568","article-title":"Clinical indirect indicators of hemodynamics do not accurately reflect systemic oxygen transport status in neonates After the Norwood procedure. Presented at American Heart Association Scientific Session, November 12-16, 2011, Orlando, Fla","volume":"124","author":"Yu","year":"2011","journal-title":"Circulation"}],"container-title":["The Journal of Thoracic and Cardiovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022522313009124?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022522313009124?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T16:53:21Z","timestamp":1758387201000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022522313009124"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["S0022522313009124"],"URL":"https:\/\/doi.org\/10.1016\/j.jtcvs.2013.07.079","relation":{},"ISSN":["0022-5223"],"issn-type":[{"value":"0022-5223","type":"print"}],"subject":[],"published":{"date-parts":[[2014,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Early postoperative systemic inflammatory response is an important determinant for adverse 2-year neurodevelopment-associated outcomes after the Norwood procedure","name":"articletitle","label":"Article Title"},{"value":"The Journal of Thoracic and Cardiovascular Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtcvs.2013.07.079","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}