{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T09:56:14Z","timestamp":1758448574694,"version":"3.44.0"},"reference-count":10,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"vor","delay-in-days":730,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jtcvsonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Thoracic and Cardiovascular Surgery"],"published-print":{"date-parts":[[2020,6]]},"DOI":"10.1016\/j.jtcvs.2019.07.076","type":"journal-article","created":{"date-parts":[[2019,8,22]],"date-time":"2019-08-22T20:11:43Z","timestamp":1566504703000},"page":"2310-2311","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Commentary: The personalized medicine of cardiothoracic surgery: Delving into subpopulations identifies the right therapy for the right patients"],"prefix":"10.1016","volume":"159","author":[{"given":"Bryan A.","family":"Whitson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Essandoh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtcvs.2019.07.076_bib1","doi-asserted-by":"crossref","first-page":"2302","DOI":"10.1016\/j.jtcvs.2019.06.020","article-title":"Levosimendan in patients with reduced left ventricular function undergoing isolated coronary or valve surgery","volume":"159","author":"van Diepen","year":"2020","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2019.07.076_bib2","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.1056\/NEJMoa1616218","article-title":"Levosimendan in patients with left ventricular dysfunction undergoing cardiac surgery","volume":"376","author":"Mehta","year":"2017","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jtcvs.2019.07.076_bib3","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.ahj.2016.09.001","volume":"182","author":"Mehta","year":"2016","journal-title":"Am Heart J"},{"key":"10.1016\/j.jtcvs.2019.07.076_bib4","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1007\/s00392-013-0649-z","article-title":"Intermittent levosimendan improves mid-term survival in chronic heart failure\u00a0patients: meta-analysis of randomised trials","volume":"103","author":"Silvetti","year":"2014","journal-title":"Clin Res Cardiol"},{"key":"10.1016\/j.jtcvs.2019.07.076_bib5","doi-asserted-by":"crossref","first-page":"2222","DOI":"10.1161\/01.CIR.102.18.2222","article-title":"Acute hemodynamic and clinical effects of levosimendan in patients with severe heart failure. Study Investigators","volume":"102","author":"Slawsky","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.jtcvs.2019.07.076_bib6","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1177\/0300060519837103","article-title":"Levosimendan as a new force in the treatment of sepsis-induced cardiomyopathy: mechanism and clinical application","volume":"47","author":"Yang","year":"2019","journal-title":"J Int Med Res"},{"key":"10.1016\/j.jtcvs.2019.07.076_bib7","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.jclinane.2017.03.011","article-title":"Levosimendan does not\u00a0provide mortality benefit over dobutamine in adult patients with septic shock:\u00a0a meta-analysis of randomized controlled trials","volume":"39","author":"Bhattacharjee","year":"2017","journal-title":"J Clin Anesth"},{"key":"10.1016\/j.jtcvs.2019.07.076_bib8","doi-asserted-by":"crossref","first-page":"e019338","DOI":"10.1136\/bmjopen-2017-019338","article-title":"Effect of levosimendan on mortality in severe sepsis and septic shock: a meta-analysis of randomised trials","volume":"8","author":"Chang","year":"2018","journal-title":"BMJ Open"},{"key":"10.1016\/j.jtcvs.2019.07.076_bib9","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.jtcvs.2011.09.020","article-title":"Levosimendan is superior to epinephrine in improving myocardial function after cardiopulmonary bypass with deep hypothermic circulatory arrest in rats","volume":"143","author":"Rungatscher","year":"2012","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2019.07.076_bib10","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1056\/NEJMoa1616325","article-title":"Levosimendan for hemodynamic support after cardiac surgery","volume":"376","author":"Landoni","year":"2017","journal-title":"N Engl J\u00a0Med"}],"container-title":["The Journal of Thoracic and Cardiovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022522319316174?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022522319316174?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T17:08:19Z","timestamp":1758388099000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022522319316174"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["S0022522319316174"],"URL":"https:\/\/doi.org\/10.1016\/j.jtcvs.2019.07.076","relation":{},"ISSN":["0022-5223"],"issn-type":[{"type":"print","value":"0022-5223"}],"subject":[],"published":{"date-parts":[[2020,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Commentary: The personalized medicine of cardiothoracic surgery: Delving into subpopulations identifies the right therapy for the right patients","name":"articletitle","label":"Article Title"},{"value":"The Journal of Thoracic and Cardiovascular Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtcvs.2019.07.076","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.jtcvs.2019.06.020","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 by The American Association for Thoracic Surgery","name":"copyright","label":"Copyright"}]}}