{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T10:14:05Z","timestamp":1791540845888,"version":"4.3.4"},"reference-count":22,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jtcvsonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Thoracic and Cardiovascular Surgery"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.jtcvs.2026.08.012","type":"journal-article","created":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T14:38:27Z","timestamp":1787927907000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Apixaban as therapeutic anticoagulation in patients supported by a fully magnetically levitated left ventricular assist device"],"prefix":"10.1016","author":[{"given":"Joshua G.","family":"Crane","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohan","family":"Samson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Moore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonali","family":"Arora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siddharth","family":"Pahwa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Gallo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yash","family":"Vaidya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gretel","family":"Monreal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaimin","family":"Trivedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5412-762X","authenticated-orcid":false,"given":"Mark S.","family":"Slaughter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.jtcvs.2026.08.012_bib1","doi-asserted-by":"crossref","first-page":"e347","DOI":"10.1161\/CIR.0000000000001209","article-title":"2024 heart disease and stroke statistics: a report of US and global data from the American Heart Association","volume":"149","author":"Martin","year":"2024","journal-title":"Circulation"},{"issue":"9","key":"10.1016\/j.jtcvs.2026.08.012_bib2","doi-asserted-by":"crossref","first-page":"e139","DOI":"10.1161\/CIR.0000000000000757","article-title":"Heart disease and stroke statistics-2020 update: a report from the American Heart Association","volume":"141","author":"Virani","year":"2020","journal-title":"Circulation"},{"issue":"12","key":"10.1016\/j.jtcvs.2026.08.012_bib3","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1001\/jama.2022.16197","article-title":"Five-year outcomes in patients with fully magnetically levitated vs axial-flow left ventricular assist devices in the MOMENTUM 3 randomized trial","volume":"328","author":"Mehra","year":"2022","journal-title":"JAMA"},{"issue":"22","key":"10.1016\/j.jtcvs.2026.08.012_bib4","doi-asserted-by":"crossref","first-page":"2171","DOI":"10.1001\/jama.2023.23204","article-title":"Aspirin and hemocompatibility events with a left ventricular assist device in advanced heart failure: the ARIES-HM3 randomized clinical trial","volume":"330","author":"Mehra","year":"2023","journal-title":"JAMA"},{"issue":"3","key":"10.1016\/j.jtcvs.2026.08.012_bib5","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1097\/MAT.0000000000001650","article-title":"Apixaban: alternative anticoagulation for HeartMate 3 ventricular assist device","volume":"68","author":"Whitehouse","year":"2022","journal-title":"ASAIO J"},{"issue":"8","key":"10.1016\/j.jtcvs.2026.08.012_bib6","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1016\/j.healun.2025.04.012","article-title":"Low-dose apixaban in HeartMate 3 LVAD patients, interim analysis of the ApixiVAD trial, a randomized controlled study","volume":"44","author":"Schnegg","year":"2025","journal-title":"J Heart Lung Transplant"},{"issue":"6","key":"10.1016\/j.jtcvs.2026.08.012_bib7","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1161\/CIRCULATIONAHA.124.069726","article-title":"A prospective randomized trial of direct oral anticoagulant therapy with a fully magnetically levitated LVAD: the DOT-HM3 study","volume":"150","author":"Netuka","year":"2024","journal-title":"Circulation"},{"issue":"9","key":"10.1016\/j.jtcvs.2026.08.012_bib8","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1016\/j.jchf.2024.04.013","article-title":"Evaluation of the hemocompatibility of the direct oral anticoagulant apixaban in left ventricular assist devices: the DOAC LVAD study","volume":"12","author":"Shah","year":"2024","journal-title":"JACC Heart Fail"},{"issue":"8","key":"10.1016\/j.jtcvs.2026.08.012_bib9","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/j.healun.2020.03.010","article-title":"Updated definitions of adverse events for trials and registries of mechanical circulatory support: a consensus statement of the mechanical circulatory support academic research consortium","volume":"39","author":"Kormos","year":"2020","journal-title":"J Heart Lung Transplant"},{"issue":"7","key":"10.1016\/j.jtcvs.2026.08.012_bib10","doi-asserted-by":"crossref","DOI":"10.1056\/EVIDoa2300067","article-title":"Apixaban or warfarin in patients with an On-X mechanical aortic valve","volume":"2","author":"Wang","year":"2023","journal-title":"NEJM Evid"},{"issue":"13","key":"10.1016\/j.jtcvs.2026.08.012_bib11","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1056\/NEJMoa1300615","article-title":"Dabigatran versus warfarin in patients with mechanical heart valves","volume":"369","author":"Eikelboom","year":"2013","journal-title":"N Engl J Med"},{"issue":"5","key":"10.1016\/j.jtcvs.2026.08.012_bib12","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.116.003709","article-title":"Increased thromboembolic events with dabigatran compared with vitamin K antagonism in left ventricular assist device patients: a randomized controlled pilot trial","volume":"10","author":"Andreas","year":"2017","journal-title":"Circ Heart Fail"},{"issue":"10","key":"10.1016\/j.jtcvs.2026.08.012_bib13","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1111\/j.1525-1594.2004.07384.x","article-title":"Computational fluid dynamics analysis of a maglev centrifugal left ventricular assist device","volume":"28","author":"Burgreen","year":"2004","journal-title":"Artif Organs"},{"issue":"7","key":"10.1016\/j.jtcvs.2026.08.012_bib14","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.120.007231","article-title":"Ex vivo assessment of different oral anticoagulant regimens on pump thrombosis in a HeartWare ventricular assist device","volume":"14","author":"Rao","year":"2021","journal-title":"Circ Heart Fail"},{"issue":"3","key":"10.1016\/j.jtcvs.2026.08.012_bib15","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1097\/MAT.0000000000001689","article-title":"Anticoagulation in the HeartMate 3 left ventricular assist device: are we finally moving the needle?","volume":"68","author":"Li","year":"2022","journal-title":"ASAIO J"},{"issue":"11","key":"10.1016\/j.jtcvs.2026.08.012_bib16","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1056\/NEJMoa2510703","article-title":"Bleeding risk with Apixaban vs. Rivaroxaban in acute venous thromboembolism","volume":"394","author":"Castellucci","year":"2026","journal-title":"N Engl J Med"},{"issue":"7","key":"10.1016\/j.jtcvs.2026.08.012_bib17","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.1161\/STROKEAHA.120.028825","article-title":"Comparative safety and effectiveness of oral anticoagulants in nonvalvular atrial fibrillation: the NAXOS study","volume":"51","author":"Van Ganse","year":"2020","journal-title":"Stroke"},{"issue":"11","key":"10.1016\/j.jtcvs.2026.08.012_bib18","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1056\/NEJMoa1107039","article-title":"Apixaban versus warfarin in patients with atrial fibrillation","volume":"365","author":"Granger","year":"2011","journal-title":"N Engl J Med"},{"issue":"7","key":"10.1016\/j.jtcvs.2026.08.012_bib19","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1093\/ehjcvp\/pvab057","article-title":"Apixaban vs. warfarin in patients with left ventricular thrombus: a prospective multicentre randomized clinical trial\u2021","volume":"8","author":"Alcalai","year":"2022","journal-title":"Eur Heart J Cardiovasc Pharmacother"},{"issue":"1","key":"10.1016\/j.jtcvs.2026.08.012_bib20","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1097\/MAT.0000000000001572","article-title":"Time in therapeutic range significantly impacts survival and adverse events in destination therapy patients","volume":"68","author":"Macaluso","year":"2022","journal-title":"ASAIO J"},{"issue":"7","key":"10.1016\/j.jtcvs.2026.08.012_bib21","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1111\/aor.13116","article-title":"Meta-analysis of time in therapeutic range in continuous-flow left ventricular assist device patients receiving warfarin","volume":"42","author":"Martinez","year":"2018","journal-title":"Artif Organs"},{"issue":"8","key":"10.1016\/j.jtcvs.2026.08.012_bib22","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2021.20064","article-title":"Oral anticoagulants for nonvalvular atrial fibrillation in patients with high risk of gastrointestinal bleeding","volume":"4","author":"Lip","year":"2021","journal-title":"JAMA Netw Open"}],"container-title":["The Journal of Thoracic and Cardiovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022522326012304?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022522326012304?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T19:59:08Z","timestamp":1790279948000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022522326012304"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":22,"alternative-id":["S0022522326012304"],"URL":"https:\/\/doi.org\/10.1016\/j.jtcvs.2026.08.012","relation":{},"ISSN":["0022-5223"],"issn-type":[{"value":"0022-5223","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Apixaban as therapeutic anticoagulation in patients supported by a fully magnetically levitated left ventricular assist device","name":"articletitle","label":"Article Title"},{"value":"The Journal of Thoracic and Cardiovascular Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtcvs.2026.08.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 by The American Association for Thoracic Surgery","name":"copyright","label":"Copyright"}]}}