{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T20:51:14Z","timestamp":1782507074242,"version":"3.54.5"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2007,12,1]],"date-time":"2007-12-01T00:00:00Z","timestamp":1196467200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,12,1]],"date-time":"2007-12-01T00:00:00Z","timestamp":1196467200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Trace Elements in Medicine and Biology"],"published-print":{"date-parts":[[2007,12]]},"DOI":"10.1016\/j.jtemb.2007.09.013","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T10:22:09Z","timestamp":1196072529000},"page":"44-48","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":67,"special_numbering":"S1","title":["Trace element requirements in critically ill burned patients"],"prefix":"10.1016","volume":"21","author":[{"given":"Mette M.","family":"Berger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Shenkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jtemb.2007.09.013_bib1","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1097\/00004630-199705000-00002","article-title":"Excessive liver oxidant stress causes mortality in response to burn injury combined with endotoxin and is prevented with antioxidants","volume":"18","author":"LaLonde","year":"1997","journal-title":"JBCR"},{"key":"10.1016\/j.jtemb.2007.09.013_bib2","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1093\/ajcn\/49.3.404","article-title":"Measured and predicted calorie requirements of adults during recovery from severe burn trauma","volume":"49","author":"Cunningham","year":"1989","journal-title":"Am J Clin Nutr"},{"issue":"Suppl","key":"10.1016\/j.jtemb.2007.09.013_bib3","doi-asserted-by":"crossref","first-page":"S7","DOI":"10.1016\/0305-4179(95)90028-4","article-title":"Burning the largest immune organ","volume":"21","author":"Allg\u00f6wer","year":"1995","journal-title":"Burns"},{"key":"10.1016\/j.jtemb.2007.09.013_bib4","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0261-5614(92)90014-H","article-title":"Selenium losses in 10 burned patients","volume":"11","author":"Berger","year":"1992","journal-title":"Clin Nutr"},{"key":"10.1016\/j.jtemb.2007.09.013_bib5","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0305-4179(92)90035-S","article-title":"Cutaneous zinc and copper losses in burns","volume":"18","author":"Berger","year":"1992","journal-title":"Burns"},{"key":"10.1016\/j.jtemb.2007.09.013_bib6","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.burns.2006.01.004","article-title":"Acute copper and zinc deficiency due to exudative losses \u2013 substitution versus nutritional requirements","volume":"32","author":"Berger","year":"2006","journal-title":"Burns"},{"issue":"Suppl","key":"10.1016\/j.jtemb.2007.09.013_bib7","first-page":"527","article-title":"Keloid hypertrophic scars: trace element alteration","volume":"11","author":"Bang","year":"1995","journal-title":"Nutrition"},{"issue":"6 Part 1","key":"10.1016\/j.jtemb.2007.09.013_bib8","doi-asserted-by":"crossref","first-page":"E952","DOI":"10.1152\/ajpendo.1997.272.6.E952","article-title":"Effects of endotoxin on zinc metabolism in human volunteers","volume":"272","author":"Gaetke","year":"1997","journal-title":"Am J Physiol (Endocrinol Metab 35)"},{"key":"10.1016\/j.jtemb.2007.09.013_bib9","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S0305-4179(02)00018-9","article-title":"Oxidative stress and metallothionein expression in the liver of rats with severe thermal injury","volume":"28","author":"Ding","year":"2002","journal-title":"Burns"},{"key":"10.1016\/j.jtemb.2007.09.013_bib10","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/0305-4179(82)90036-5","article-title":"Studies on the serum levels of iron, copper and zinc and the urinary excretion of zinc after burn injury","volume":"8","author":"Shakespeare","year":"1982","journal-title":"Burns"},{"key":"10.1016\/j.jtemb.2007.09.013_bib11","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1177\/0148607184008006695","article-title":"Selenium depletion in burn patients","volume":"8","author":"Hunt","year":"1984","journal-title":"JPEN"},{"key":"10.1016\/j.jtemb.2007.09.013_bib12","first-page":"513","article-title":"Trace elements in trauma and burns","volume":"1","author":"Berger","year":"1998","journal-title":"Curr Opin Clin Nutr Metab Care"},{"issue":"Part 5","key":"10.1016\/j.jtemb.2007.09.013_bib13","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1177\/000456329603300513","article-title":"Severe hypocupraemia in a patient with extensive burn injuries","volume":"33","author":"Sampson","year":"1996","journal-title":"Ann Clin Biochem"},{"key":"10.1016\/j.jtemb.2007.09.013_bib14","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1093\/ajcn\/85.5.1301","article-title":"Trace element supplements after major burns increase burned skin concentrations and modulate local protein metabolism, but not whole body substrate metabolism","volume":"85","author":"Berger","year":"2007","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jtemb.2007.09.013_bib15","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1001\/archsurg.1970.01340220025005","article-title":"Zinc concentrations within healing wounds","volume":"100","author":"Henzel","year":"1970","journal-title":"Arch Surg"},{"issue":"1","key":"10.1016\/j.jtemb.2007.09.013_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.clnu.2005.11.006","article-title":"The key role of micronutrients","volume":"25","author":"Shenkin","year":"2006","journal-title":"Clin Nutr"},{"key":"10.1016\/j.jtemb.2007.09.013_bib17","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1093\/ajcn\/10.2.95","article-title":"Uncertainties in the interpretation and validity of long-term balance studies","volume":"10","author":"Walker","year":"1962","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jtemb.2007.09.013_bib18","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/S0140-6736(73)91537-7","article-title":"Urinary zinc levels as an indication of muscle catabolism","volume":"i","author":"Fell","year":"1973","journal-title":"Lancet"},{"key":"10.1016\/j.jtemb.2007.09.013_bib19","first-page":"538","article-title":"Increased urinary zinc excretion after thermal injury","volume":"118","author":"Boosalis","year":"1991","journal-title":"J Lab Clin Med"},{"issue":"6","key":"10.1016\/j.jtemb.2007.09.013_bib20","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/j.burns.2005.04.026","article-title":"Impaired zinc and copper status in children with burn injuries: need to reassess nutritional requirements","volume":"31","author":"Voruganti","year":"2005","journal-title":"Burns"},{"key":"10.1016\/j.jtemb.2007.09.013_bib21","first-page":"275","article-title":"Multi-trace element supplementation in enteral formulas for burned guinea pigs","volume":"7","author":"Nelson","year":"1991","journal-title":"Nutrition"},{"issue":"6","key":"10.1016\/j.jtemb.2007.09.013_bib22","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1016\/j.freeradbiomed.2005.04.024","article-title":"Optimization of selenium status by a single intra-peritoneal injection of Se in Se deficient rat: possible application to burned patient treatment","volume":"39","author":"Agay","year":"2005","journal-title":"Free Rad Biol Med"},{"key":"10.1016\/j.jtemb.2007.09.013_bib23","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.burns.2004.11.010","article-title":"Alterations of antioxidant trace elements (Zn, Se, Cu) and related metaloenzymes in plasma and tissues following burn injury in rats","volume":"31","author":"Agay","year":"2005","journal-title":"Burns"},{"key":"10.1016\/j.jtemb.2007.09.013_bib24","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1097\/01.ta.0000205640.82459.d6","article-title":"Kinetic evolution of oxidative stress and selenium status in plasma and tissues following burn injury in selenium deficient and selenium supplemented rats","volume":"60","author":"Sandre","year":"2006","journal-title":"J Trauma"},{"key":"10.1016\/j.jtemb.2007.09.013_bib25","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0305-4179(78)90057-8","article-title":"Zinc and copper replacement therapy in children with deep burns","volume":"5","author":"Pochon","year":"1979","journal-title":"Burns"},{"key":"10.1016\/j.jtemb.2007.09.013_bib26","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1080\/07315724.1991.10718127","article-title":"Zinc and copper status of severely burned children during TPN","volume":"10","author":"Cunningham","year":"1991","journal-title":"J Am Coll Nutr"},{"issue":"4","key":"10.1016\/j.jtemb.2007.09.013_bib27","first-page":"329","article-title":"Burn severity, copper dose, and plasma ceruloplasmin in burned children during total parenteral nutrition","volume":"9","author":"Cunningham","year":"1993","journal-title":"Nutrition"},{"issue":"JUL\u2013AUG (4)","key":"10.1016\/j.jtemb.2007.09.013_bib28","first-page":"327","article-title":"Influence of large intakes of trace elements on recovery after major burns","volume":"10","author":"Berger","year":"1994","journal-title":"Nutrition"},{"key":"10.1016\/j.jtemb.2007.09.013_bib29","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1093\/ajcn\/68.2.365","article-title":"Trace element supplementation modulates pulmonary infection rates after major burns: a double blind, placebo controlled trial","volume":"68","author":"Berger","year":"1998","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jtemb.2007.09.013_bib30","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1093\/ajcn\/85.5.1293","article-title":"Trace element supplements after major burns modulate antioxidant status and clinical course by way of increased tissue trace element concentration","volume":"85","author":"Berger","year":"2007","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jtemb.2007.09.013_bib31","first-page":"91","article-title":"Energy, trace element and vitamin requirements in major burns","volume":"2","author":"Berger","year":"2002","journal-title":"Crit Care Shock"},{"key":"10.1016\/j.jtemb.2007.09.013_bib32","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/0305-4179(95)00031-6","article-title":"Relations between copper, zinc and selenium intakes and malondialdehyde excretion after major burns","volume":"21","author":"Berger","year":"1995","journal-title":"Burns"},{"key":"10.1016\/j.jtemb.2007.09.013_bib33","doi-asserted-by":"crossref","unstructured":"Berger MM, Eggimann P, Heyland DK, Chiol\u00e9ro RL, Revelly JP, Day A, Raffoul W, Shenkin A. Reduction of nosocomial pneumonia after major burns by trace element supplementation: aggregation of two randomised trials. Crit Care 2006;10:R153:e-pub 2 Nov.","DOI":"10.1186\/cc5084"},{"key":"10.1016\/j.jtemb.2007.09.013_bib34","doi-asserted-by":"crossref","first-page":"2166","DOI":"10.1001\/jama.1978.03290200044019","article-title":"Hypocupremia induced by zinc therapy in adults","volume":"240","author":"Prasad","year":"1978","journal-title":"JAMA"}],"container-title":["Journal of Trace Elements in Medicine and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0946672X07001095?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0946672X07001095?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T19:06:11Z","timestamp":1760555171000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0946672X07001095"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,12]]},"references-count":34,"alternative-id":["S0946672X07001095"],"URL":"https:\/\/doi.org\/10.1016\/j.jtemb.2007.09.013","relation":{},"ISSN":["0946-672X"],"issn-type":[{"value":"0946-672X","type":"print"}],"subject":[],"published":{"date-parts":[[2007,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Trace element requirements in critically ill burned patients","name":"articletitle","label":"Article Title"},{"value":"Journal of Trace Elements in Medicine and Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtemb.2007.09.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}]}}