{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T22:39:59Z","timestamp":1780699199676,"version":"3.54.1"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81273131"],"award-info":[{"award-number":["81273131"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002799","name":"China Capital Medical University","doi-asserted-by":"publisher","award":["12JL02"],"award-info":[{"award-number":["12JL02"]}],"id":[{"id":"10.13039\/501100002799","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Trace Elements in Medicine and Biology"],"published-print":{"date-parts":[[2015,4]]},"DOI":"10.1016\/j.jtemb.2015.01.009","type":"journal-article","created":{"date-parts":[[2015,1,22]],"date-time":"2015-01-22T05:48:07Z","timestamp":1421905687000},"page":"37-42","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Development of magnetic separation and quantum dots labeled immunoassay for the detection of mercury in biological samples"],"prefix":"10.1016","volume":"30","author":[{"given":"Hubo","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengmeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jilong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mi","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiwei","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peili","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtemb.2015.01.009_bib0170","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.envres.2014.03.004","article-title":"Mercury pollution in fish from South China Sea: levels, species-specific accumulation, and possible sources","volume":"131","author":"Liu","year":"2014","journal-title":"Environ Res"},{"key":"10.1016\/j.jtemb.2015.01.009_bib0175","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.aquatox.2013.09.023","article-title":"Mercury induced community tolerance in microbial biofilms is related to pollution gradients in a long-term polluted river","volume":"144\u2013145","author":"Kovac Virsek","year":"2013","journal-title":"Aquat Toxicol"},{"issue":"6153","key":"10.1016\/j.jtemb.2015.01.009_bib0180","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1126\/science.341.6153.1448","article-title":"Mercury pollution, Gold's dark side","volume":"341","author":"Wade","year":"2013","journal-title":"Science"},{"issue":"6","key":"10.1016\/j.jtemb.2015.01.009_bib0185","doi-asserted-by":"crossref","first-page":"2666","DOI":"10.3390\/ijerph7062666","article-title":"Methylmercury exposure and health effects from rice and fish consumption: a review","volume":"7","author":"Li","year":"2010","journal-title":"Int J Environ Res Public Health"},{"issue":"21","key":"10.1016\/j.jtemb.2015.01.009_bib0190","doi-asserted-by":"crossref","first-page":"7994","DOI":"10.1021\/es1030917","article-title":"China needs to control mercury emissions from municipal solid waste (MSW) incineration","volume":"44","author":"Cheng","year":"2010","journal-title":"Environ Sci Technol"},{"issue":"2","key":"10.1016\/j.jtemb.2015.01.009_bib0195","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1021\/es2026517","article-title":"Mercury in municipal solid waste in China and its control: a review","volume":"46","author":"Cheng","year":"2012","journal-title":"Environ Sci Technol"},{"issue":"12","key":"10.1016\/j.jtemb.2015.01.009_bib0200","doi-asserted-by":"crossref","first-page":"252R","DOI":"10.1021\/ac00084a012","article-title":"Atomic absorption, atomic emission, and flame emission spectrometry","volume":"66","author":"Jackson","year":"1994","journal-title":"Anal Chem"},{"issue":"6025","key":"10.1016\/j.jtemb.2015.01.009_bib0205","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1038\/316265a0","article-title":"Antibodies against metal chelates","volume":"316","author":"Reardan","year":"1985","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.jtemb.2015.01.009_bib0210","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1021\/bc049889p","article-title":"Novel monoclonal antibodies with specificity for chelated uranium(VI): isolation and binding properties","volume":"15","author":"Blake","year":"2004","journal-title":"Bioconjugate Chem"},{"issue":"1","key":"10.1016\/j.jtemb.2015.01.009_bib0215","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/15321819.2013.774817","article-title":"Immunoassay for lead ions: analysis of spiked food samples","volume":"35","author":"Mandappa","year":"2014","journal-title":"J Immunoass Immunochem"},{"issue":"5","key":"10.1016\/j.jtemb.2015.01.009_bib0220","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1016\/j.envpol.2010.01.002","article-title":"A competitive indirect enzyme-linked immunoassay for lead ion measurement using mAbs against the lead-DTPA complex","volume":"158","author":"Xiang","year":"2010","journal-title":"Environ Pollut"},{"issue":"2","key":"10.1016\/j.jtemb.2015.01.009_bib0225","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1039\/B918623A","article-title":"Magnetic bead based assay for C-reactive protein using quantum-dot fluorescence labeling and immunoaffinity separation","volume":"135","author":"Zhu","year":"2010","journal-title":"Analyst"},{"issue":"1","key":"10.1016\/j.jtemb.2015.01.009_bib0230","doi-asserted-by":"crossref","first-page":"15","DOI":"10.4315\/0362-028X.JFP-13-225","article-title":"Simultaneous immunomagnetic separation method for the detection of Escherichia coli O26, O111, and O157 from food samples","volume":"77","author":"Kanki","year":"2014","journal-title":"J Food Prot"},{"issue":"10","key":"10.1016\/j.jtemb.2015.01.009_bib0235","doi-asserted-by":"crossref","first-page":"4249","DOI":"10.1016\/j.bios.2011.04.023","article-title":"Rapid and sensitive detection of cancer cells by coupling with quantum dots and immunomagnetic separation at low concentrations","volume":"26","author":"Hsieh","year":"2011","journal-title":"Biosens Bioelectron"},{"issue":"11","key":"10.1016\/j.jtemb.2015.01.009_bib0240","doi-asserted-by":"crossref","first-page":"7707","DOI":"10.1166\/jnn.2013.7829","article-title":"A simple preparation of a stable CdS-polyacrylamide nanocomposite: structure, thermal and optical properties","volume":"13","author":"Bach","year":"2013","journal-title":"J Nanosci Nanotechnol"},{"issue":"3","key":"10.1016\/j.jtemb.2015.01.009_bib0245","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1166\/jbn.2013.1561","article-title":"Thiol antioxidant-functionalized CdSe\/ZnS quantum dots: synthesis, characterization, cytotoxicity","volume":"9","author":"Zheng","year":"2013","journal-title":"J Biomed Nanotechnol"},{"issue":"4","key":"10.1016\/j.jtemb.2015.01.009_bib0250","doi-asserted-by":"crossref","first-page":"8603","DOI":"10.3390\/ijms14048603","article-title":"A one-step homogeneous sandwich immunosensor for Salmonella detection based on magnetic nanoparticles (MNPs) and quantum dots (QDs)","volume":"14","author":"Kuang","year":"2013","journal-title":"Int J Mol Sci"},{"issue":"5","key":"10.1016\/j.jtemb.2015.01.009_bib0255","doi-asserted-by":"crossref","first-page":"e20026","DOI":"10.1371\/journal.pone.0020026","article-title":"Detection of pathogenic mycobacteria based on functionalized quantum dots coupled with immunomagnetic separation","volume":"6","author":"Liandris","year":"2011","journal-title":"PLoS ONE"},{"issue":"1","key":"10.1016\/j.jtemb.2015.01.009_bib0260","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/s10895-013-1315-6","article-title":"Development of a fluorescent enzyme-linked DNA aptamer-magnetic bead sandwich assay and portable fluorometer for sensitive and rapid leishmania detection in sandflies","volume":"24","author":"Bruno","year":"2014","journal-title":"J Fluoresc"},{"key":"10.1016\/j.jtemb.2015.01.009_bib0265","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.aca.2012.08.036","article-title":"The sandwich-type electrochemiluminescence immunosensor for alpha-fetoprotein based on enrichment by Fe3O4-Au magnetic nano probes and signal amplification by CdS-Au composite nanoparticles labeled anti-AFP","volume":"746","author":"Zhou","year":"2012","journal-title":"Anal Chim Acta"},{"issue":"2","key":"10.1016\/j.jtemb.2015.01.009_bib0270","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1021\/bi0267339","article-title":"Allosteric binding properties of a monoclonal antibody and its Fab fragment","volume":"42","author":"Blake","year":"2003","journal-title":"Biochemistry"},{"issue":"2","key":"10.1016\/j.jtemb.2015.01.009_bib0275","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1006\/abio.1997.2161","article-title":"The quantification of protein amino groups by the trinitrobenzenesulfonic acid method: a reexamination","volume":"249","author":"Cayot","year":"1997","journal-title":"Anal Biochem"},{"issue":"3","key":"10.1016\/j.jtemb.2015.01.009_bib0285","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0300-483X(99)00076-1","article-title":"Protein binding of mercury in milk and plasma from mice and man \u2013 a comparison between methylmercury and inorganic mercury","volume":"137","author":"Sundberg","year":"1999","journal-title":"Toxicology"},{"key":"10.1016\/j.jtemb.2015.01.009_bib0290","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.envint.2014.05.010","article-title":"Association of body burden of mercury with liver function test status in the U.S. population","volume":"70C","author":"Lin","year":"2014","journal-title":"Environ Int"},{"issue":"44","key":"10.1016\/j.jtemb.2015.01.009_bib0295","doi-asserted-by":"crossref","first-page":"27677","DOI":"10.1074\/jbc.271.44.27677","article-title":"Metal binding properties of a monoclonal antibody directed toward metal-chelate complexes","volume":"271","author":"Blake","year":"1996","journal-title":"J Biol Chem"},{"issue":"13","key":"10.1016\/j.jtemb.2015.01.009_bib0300","doi-asserted-by":"crossref","first-page":"2651","DOI":"10.1021\/ac980027p","article-title":"Photobleaching of fluorescent dyes under conditions used for single-molecule detection: evidence of two-step photolysis","volume":"70","author":"Eggeling","year":"1998","journal-title":"Anal Chem"},{"key":"10.1016\/j.jtemb.2015.01.009_bib0305","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.bios.2014.05.049","article-title":"Using \u201cdioscorea batatas bean\u201d-like silver nanoparticles based localized surface plasmon resonance to enhance the fluorescent signal of zinc oxide quantum dots in a DNA sensor","volume":"61C","author":"Chu","year":"2014","journal-title":"Biosens Bioelectron"},{"issue":"17","key":"10.1016\/j.jtemb.2015.01.009_bib0310","doi-asserted-by":"crossref","first-page":"173201","DOI":"10.1088\/0953-8984\/26\/17\/173201","article-title":"Silicon quantum dots: surface matters","volume":"26","author":"Dohnalova","year":"2014","journal-title":"J Phy Condens Matter: Inst Phys J"},{"issue":"1","key":"10.1016\/j.jtemb.2015.01.009_bib0315","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1042\/BJ20101593","article-title":"How the biotin-streptavidin interaction was made even stronger: investigation via crystallography and a chimaeric tetramer","volume":"435","author":"Chivers","year":"2011","journal-title":"Biochem J"},{"issue":"5385","key":"10.1016\/j.jtemb.2015.01.009_bib0320","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.1126\/science.281.5385.2016","article-title":"Quantum dot bioconjugates for ultrasensitive nonisotopic detection","volume":"281","author":"Chan","year":"1998","journal-title":"Science"},{"issue":"8","key":"10.1016\/j.jtemb.2015.01.009_bib0325","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.1016\/j.bios.2010.01.007","article-title":"QDs-DNA nanosensor for the detection of hepatitis B virus DNA and the single-base mutants","volume":"25","author":"Wang","year":"2010","journal-title":"Biosens Bioelectron"},{"issue":"6","key":"10.1016\/j.jtemb.2015.01.009_bib0330","doi-asserted-by":"crossref","first-page":"e11323","DOI":"10.1371\/journal.pone.0011323","article-title":"Specific visualization of glioma cells in living low-grade tumor tissue","volume":"5","author":"Kantelhardt","year":"2010","journal-title":"PLoS ONE"}],"container-title":["Journal of Trace Elements in Medicine and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0946672X15000115?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0946672X15000115?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,26]],"date-time":"2018-09-26T00:54:48Z","timestamp":1537923288000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0946672X15000115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":32,"alternative-id":["S0946672X15000115"],"URL":"https:\/\/doi.org\/10.1016\/j.jtemb.2015.01.009","relation":{},"ISSN":["0946-672X"],"issn-type":[{"value":"0946-672X","type":"print"}],"subject":[],"published":{"date-parts":[[2015,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Development of magnetic separation and quantum dots labeled immunoassay for the detection of mercury in biological samples","name":"articletitle","label":"Article Title"},{"value":"Journal of Trace Elements in Medicine and Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtemb.2015.01.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}]}}