{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T03:37:10Z","timestamp":1791430630240,"version":"4.3.3"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Dr. Valentin Aplas-Stiftung"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Trace Elements in Medicine and Biology"],"published-print":{"date-parts":[[2019,5]]},"DOI":"10.1016\/j.jtemb.2019.02.006","type":"journal-article","created":{"date-parts":[[2019,2,15]],"date-time":"2019-02-15T02:47:33Z","timestamp":1550198853000},"page":"129-134","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Levels of serum trace elements in patients with primary open-angle glaucoma"],"prefix":"10.1016","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4371-8605","authenticated-orcid":false,"given":"Alexander","family":"Fick","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anselm","family":"J\u00fcnemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Michalke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianna","family":"Lucio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bettina","family":"Hohberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtemb.2019.02.006_bib0005","series-title":"Augenheilkunde, 5. Aufl. ed.","author":"Lang","year":"2014"},{"key":"10.1016\/j.jtemb.2019.02.006_bib0010","article-title":"26 Years of the erlangen glaucoma registry: demographic and perimetric characteristics of patients through the ages","author":"Hohberger","year":"2017","journal-title":"Klinische Monatsblatter fur Augenheilkunde"},{"issue":"1","key":"10.1016\/j.jtemb.2019.02.006_bib0015","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.coph.2012.09.008","article-title":"Oxidative stress and mitochondrial dysfunction in glaucoma","volume":"13","author":"Chrysostomou","year":"2013","journal-title":"Curr. Opin. Pharmacol."},{"key":"10.1016\/j.jtemb.2019.02.006_bib0020","first-page":"1332","article-title":"Oxidative stress response signaling pathways in trabecular meshwork cells and their effects on cell viability","volume":"19","author":"Awai-Kasaoka","year":"2013","journal-title":"Mol. Vis."},{"issue":"4","key":"10.1016\/j.jtemb.2019.02.006_bib0025","doi-asserted-by":"crossref","first-page":"382","DOI":"10.3109\/10715762.2011.653969","article-title":"Mechanisms of free radical-induced damage to DNA","volume":"46","author":"Dizdaroglu","year":"2012","journal-title":"Free Radic. Res."},{"issue":"0","key":"10.1016\/j.jtemb.2019.02.006_bib0030","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.5604\/17322693.1229074","article-title":"Trace elements as an activator of antioxidant enzymes","volume":"70","author":"Wolonciej","year":"2016","journal-title":"Postepy higieny i medycyny doswiadczalnej (Online)"},{"issue":"2-3","key":"10.1016\/j.jtemb.2019.02.006_bib0035","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.tox.2011.03.001","article-title":"Advances in metal-induced oxidative stress and human disease","volume":"283","author":"Jomova","year":"2011","journal-title":"Toxicology"},{"key":"10.1016\/j.jtemb.2019.02.006_bib0040","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.nbd.2015.08.007","article-title":"The relationship between iron dyshomeostasis and amyloidogenesis in Alzheimer\u2019s disease: two sides of the same coin","volume":"81","author":"Peters","year":"2015","journal-title":"Neurobiol. Dis."},{"issue":"2","key":"10.1016\/j.jtemb.2019.02.006_bib0045","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1167\/iovs.11-9038","article-title":"The association between glaucoma prevalence and supplementation with the oxidants calcium and iron","volume":"53","author":"Wang","year":"2012","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"3","key":"10.1016\/j.jtemb.2019.02.006_bib0050","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.bbrc.2016.10.126","article-title":"Redox dynamics of manganese as a mitochondrial life-death switch","volume":"482","author":"Smith","year":"2017","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"1","key":"10.1016\/j.jtemb.2019.02.006_bib0055","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1023\/A:1024405119018","article-title":"Cadmium-induced apoptosis in C6 glioma cells: influence of oxidative stress","volume":"17","author":"Watjen","year":"2004","journal-title":"Biometals"},{"key":"10.1016\/j.jtemb.2019.02.006_bib0060","doi-asserted-by":"crossref","first-page":"457327","DOI":"10.4061\/2011\/457327","article-title":"Oxidative\u2009stress in lead and cadmium toxicity and its amelioration","volume":"2011","author":"Patra","year":"2011","journal-title":"Vet. Med. Int."},{"issue":"4-5","key":"10.1016\/j.jtemb.2019.02.006_bib0065","first-page":"135","article-title":"[Experimental studies on lesions of eye tissues in cobalt intoxication]","volume":"96","author":"Monies","year":"1994","journal-title":"Klinika oczna"},{"issue":"1","key":"10.1016\/j.jtemb.2019.02.006_bib0070","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/S0002-9394(03)00788-8","article-title":"Oxidative stress markers in aqueous humor of glaucoma patients","volume":"137","author":"Ferreira","year":"2004","journal-title":"Am. J. Ophthalmol."},{"issue":"11","key":"10.1016\/j.jtemb.2019.02.006_bib0075","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1136\/bjo.74.11.661","article-title":"Aqueous humour and serum zinc and copper concentrations of patients with glaucoma and cataract","volume":"74","author":"Akyol","year":"1990","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.jtemb.2019.02.006_bib0080","series-title":"Biomorphometrie des Nervus opticus; 24 Tabellen, Enke, Stuttgart","author":"Jonas","year":"1989"},{"key":"10.1016\/j.jtemb.2019.02.006_bib0085","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/bs.pbr.2015.06.001","article-title":"Oxidative stress and mitochondrial failure in the pathogenesis of glaucoma neurodegeneration","volume":"220","author":"Pinazo-Duran","year":"2015","journal-title":"Prog. Brain Res."},{"issue":"4","key":"10.1016\/j.jtemb.2019.02.006_bib0090","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1097\/IJG.0b013e31815c3a7f","article-title":"Oxidative stress in primary open-angle glaucoma","volume":"17","author":"Zanon-Moreno","year":"2008","journal-title":"J. Glaucoma"},{"issue":"8","key":"10.1016\/j.jtemb.2019.02.006_bib0095","doi-asserted-by":"crossref","first-page":"713","DOI":"10.3109\/02713683.2011.584370","article-title":"Antioxidant status and oxidative stress in primary open angle glaucoma and pseudoexfoliative glaucoma","volume":"36","author":"Erdurmu\u015f","year":"2011","journal-title":"Curr. Eye Res."},{"issue":"9","key":"10.1016\/j.jtemb.2019.02.006_bib0100","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1136\/bjo.2007.125997","article-title":"Relationship between glaucoma and selenium levels in plasma and aqueous humour","volume":"93","author":"Bruhn","year":"2009","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.jtemb.2019.02.006_bib0105","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.jtemb.2017.10.003","article-title":"Levels of aqueous humor trace elements in patients with open-angle glaucoma","volume":"45","author":"Hohberger","year":"2018","journal-title":"J. Trace Elem. Med. Biol."},{"issue":"1","key":"10.1016\/j.jtemb.2019.02.006_bib0110","first-page":"33","article-title":"N-acetylcysteine prevents cadmium-induced apoptosis in human breast cancer MDA-MB468 cell line","volume":"60","author":"Panjehpour","year":"2014","journal-title":"Cell. Mol. Biol. (Noisy-le-grand)"},{"issue":"1-3","key":"10.1016\/j.jtemb.2019.02.006_bib0115","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1007\/s12011-014-9955-1","article-title":"Effect of Physalis peruviana L. on cadmium-induced testicular toxicity in rats","volume":"159","author":"Othman","year":"2014","journal-title":"Biol. Trace Elem. Res."},{"issue":"21","key":"10.1016\/j.jtemb.2019.02.006_bib0120","doi-asserted-by":"crossref","first-page":"12703","DOI":"10.1074\/jbc.273.21.12703","article-title":"Disruption of the intracellular sulfhydryl homeostasis by cadmium-induced oxidative stress leads to protein thiolation and ubiquitination in neuronal cells","volume":"273","author":"Figueiredo-Pereira","year":"1998","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.jtemb.2019.02.006_bib0125","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1023\/A:1009286130324","article-title":"Lipid peroxidative damage on cadmium exposure and alterations in antioxidant system in rat erythrocytes: a study with relation to time","volume":"11","author":"Sarkar","year":"1998","journal-title":"Biometals"},{"issue":"4","key":"10.1016\/j.jtemb.2019.02.006_bib0130","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1039\/c4mt00022f","article-title":"Manganese leads to an increase in markers of oxidative stress as well as to a shift in the ratio of Fe(II)\/(III) in rat brain tissue","volume":"6","author":"Fernsebner","year":"2014","journal-title":"Metallomics"},{"issue":"6","key":"10.1016\/j.jtemb.2019.02.006_bib0135","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1111\/jnc.14580","article-title":"Manganese causes neurotoxic iron accumulation via translational repression of Amyloid Precursor Protein (APP) and H-Ferritin","volume":"147","author":"Venkataramani","year":"2018","journal-title":"J. Neurochem."},{"key":"10.1016\/j.jtemb.2019.02.006_bib0140","doi-asserted-by":"crossref","first-page":"632","DOI":"10.3389\/fnins.2018.00632","article-title":"Iron and alzheimer\u2019s disease: from pathogenesis to therapeutic implications","volume":"12","author":"Liu","year":"2018","journal-title":"Front. Neurosci."},{"issue":"2-3","key":"10.1016\/j.jtemb.2019.02.006_bib0145","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.tox.2011.03.001","article-title":"Advances in metal-induced oxidative stress and human disease","volume":"283","author":"Jomova","year":"2011","journal-title":"Toxicology"},{"issue":"2","key":"10.1016\/j.jtemb.2019.02.006_bib0150","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1111\/j.1349-7006.2009.01394.x","article-title":"Body iron store as a predictor of oxidative DNA damage in healthy men and women","volume":"101","author":"Hori","year":"2010","journal-title":"Cancer Sci."},{"issue":"6","key":"10.1016\/j.jtemb.2019.02.006_bib0155","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.preteyeres.2007.07.004","article-title":"Iron homeostasis and toxicity in retinal degeneration","volume":"26","author":"He","year":"2007","journal-title":"Prog. Retin. Eye Res."},{"issue":"1","key":"10.1016\/j.jtemb.2019.02.006_bib0160","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1167\/iovs.06-0528","article-title":"Differential sensitivity of cones to iron-mediated oxidative damage","volume":"48","author":"Rogers","year":"2007","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"2","key":"10.1016\/j.jtemb.2019.02.006_bib0165","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1167\/iovs.11-9038","article-title":"The association between glaucoma prevalence and supplementation with the oxidants calcium and iron","volume":"53","author":"Wang","year":"2012","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"6","key":"10.1016\/j.jtemb.2019.02.006_bib0170","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1111\/aos.13662","article-title":"The relation between dietary intake and glaucoma: a systematic review","volume":"96","author":"Ramdas","year":"2018","journal-title":"Acta Ophthalmol."},{"issue":"10","key":"10.1016\/j.jtemb.2019.02.006_bib0175","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.2174\/0929867053764635","article-title":"Metals, toxicity and oxidative stress","volume":"12","author":"Valko","year":"2005","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.jtemb.2019.02.006_bib0180","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.12659\/MSM.895352","article-title":"Determination of serum ceruloplasmin concentration in patients with primary open angle glaucoma with cataract and patients with cataract only: a pilot study","volume":"22","author":"Sarnat-Kucharczyk","year":"2016","journal-title":"Med. Sci. Monit."},{"issue":"10","key":"10.1016\/j.jtemb.2019.02.006_bib0185","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0164983","article-title":"Three toxic heavy metals in open-angle glaucoma with low-teen and high-teen intraocular pressure: a cross-sectional study from South Korea","volume":"11","author":"Lee","year":"2016","journal-title":"PLoS One"},{"issue":"10","key":"10.1016\/j.jtemb.2019.02.006_bib0190","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1001\/jamaophthalmol.2015.2438","article-title":"Association between body levels of trace metals and glaucoma prevalence","volume":"133","author":"Lin","year":"2015","journal-title":"JAMA Ophthalmol."},{"issue":"11","key":"10.1016\/j.jtemb.2019.02.006_bib0195","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1136\/bjo.74.11.661","article-title":"Aqueous-humor and serum zinc and copper concentrations of patients with glaucoma and cataract","volume":"74","author":"Akyol","year":"1990","journal-title":"Br. J. Ophthalmol."},{"issue":"10","key":"10.1016\/j.jtemb.2019.02.006_bib0200","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1001\/jamaophthalmol.2015.2438","article-title":"Association between body levels of trace metals and Glaucoma prevalence","volume":"133","author":"Lin","year":"2015","journal-title":"JAMA Ophthalmol."},{"key":"10.1016\/j.jtemb.2019.02.006_bib0205","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.envint.2018.06.040","article-title":"Iron-processing genotypes, nutrient intakes, and cadmium levels in the Normative Aging Study: evidence of sensitive subpopulations in cadmium risk assessment","volume":"119","author":"Ciesielski","year":"2018","journal-title":"Environ. Int."},{"issue":"1","key":"10.1016\/j.jtemb.2019.02.006_bib0210","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.toxlet.2008.04.001","article-title":"Effect of hemolytic and iron-deficiency anemia on intestinal absorption and tissue accumulation of cadmium","volume":"179","author":"Min","year":"2008","journal-title":"Toxicol. Lett."},{"issue":"1","key":"10.1016\/j.jtemb.2019.02.006_bib0215","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.toxlet.2004.03.015","article-title":"Dietary iron regulates intestinal cadmium absorption through iron transporters in rats","volume":"152","author":"Ryu","year":"2004","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.jtemb.2019.02.006_bib0220","doi-asserted-by":"crossref","DOI":"10.1007\/s12011-018-1536-2","article-title":"Effect of Fe and Cd Co-exposure on testicular steroid metabolism, morphometry, and spermatogenesis in mice","author":"Abarikwu","year":"2018","journal-title":"Biol. Trace Elem. Res."}],"container-title":["Journal of Trace Elements in Medicine and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0946672X18307168?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0946672X18307168?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,3,22]],"date-time":"2019-03-22T11:39:02Z","timestamp":1553254742000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0946672X18307168"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":44,"alternative-id":["S0946672X18307168"],"URL":"https:\/\/doi.org\/10.1016\/j.jtemb.2019.02.006","relation":{},"ISSN":["0946-672X"],"issn-type":[{"value":"0946-672X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Levels of serum trace elements in patients with primary open-angle glaucoma","name":"articletitle","label":"Article Title"},{"value":"Journal of Trace Elements in Medicine and Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtemb.2019.02.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}]}}