{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T08:20:58Z","timestamp":1769242858235,"version":"3.49.0"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"National Science Foundation\u2019s Major Research Instrumentation Program (NSF MRI","award":["CHE-1531698"],"award-info":[{"award-number":["CHE-1531698"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Trace Elements in Medicine and Biology"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1016\/j.jtemb.2019.04.005","type":"journal-article","created":{"date-parts":[[2019,4,12]],"date-time":"2019-04-12T11:38:25Z","timestamp":1555069105000},"page":"62-68","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Effects of platinum-based anticancer drugs on the trace element profile of liver and kidney tissue from mice"],"prefix":"10.1016","volume":"54","author":[{"given":"John T.","family":"Sloop","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jake A.","family":"Carter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich","family":"Bierbach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bradley T.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George L.","family":"Donati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtemb.2019.04.005_bib0005","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.ejphar.2014.07.025","article-title":"Cisplatin in cancer therapy: molecular mechanisms of action","volume":"740","author":"Dasari","year":"2014","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0010","series-title":"Metal Ions in Toxicology: Effects, Interactions, Interdependencies","author":"Sigel","year":"2011"},{"key":"10.1016\/j.jtemb.2019.04.005_bib0015","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1111\/j.1349-7006.2008.00854.x","article-title":"Intracellular zinc homeostasis and zinc signaling","volume":"99","author":"Murakami","year":"2008","journal-title":"Cancer Sci."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0020","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.mrfmmm.2003.08.023","article-title":"Iron overload and its associations with cancer risk in humans: evidence for iron as a carcinogenic metal","volume":"533","author":"Huang","year":"2003","journal-title":"Mutat. Res."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0025","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.bcp.2010.09.012","article-title":"The platinum (II) complex [Pt(O,O\u2019-acac)(\u03b3-acac)(DMS)] alters the intracellular calcium homeostasis in MCF-7 breast cancer cells","volume":"81","author":"Muscella","year":"2011","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0030","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/j.neuro.2009.04.014","article-title":"Anti-cancer drugs interfere with intracellular calcium signaling","volume":"30","author":"Florea","year":"2009","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.jtemb.2019.04.005_bib0035","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S1040-8428(01)00219-0","article-title":"Particular aspects of platinum compounds used at present in cancer treatment","volume":"42","author":"Desoize","year":"2002","journal-title":"Crit. Rev. Oncol. Hematol."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0040","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.jtemb.2014.02.005","article-title":"Cisplatin administration influences on toxic and non-essential element metabolism in rats","volume":"28","author":"Szentmih\u00e1lyi","year":"2014","journal-title":"J. Trace Elem. Med. Biol."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0045","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1039\/C4MT00238E","article-title":"Mechanisms of cell uptake and toxicity of the anticancer drug cisplatin","volume":"6","author":"Eljack","year":"2014","journal-title":"Metallomics"},{"key":"10.1016\/j.jtemb.2019.04.005_bib0050","series-title":"Inductively Coupled Plasma Mass Spectrometry","author":"Montaser","year":"1998"},{"key":"10.1016\/j.jtemb.2019.04.005_bib0055","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1366\/12-06681","article-title":"Inductively coupled plasma-mass spectrometry (ICP-MS) for quantitative analysis in environmental and life sciences: a review of challenges, solutions, and trends","volume":"66","author":"Pr\u00f6frock","year":"2012","journal-title":"Appl. Spectosc."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0060","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.jpba.2008.01.047","article-title":"Analytical methodologies for the determination of cisplatin","volume":"47","author":"Bosch","year":"2008","journal-title":"J. Pharm. Biomed."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0065","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1039\/b901960j","article-title":"Multi-elemental fingerprinting of plant tissue by semi-quantitative ICP-MS and chemometrics","volume":"24","author":"Laursen","year":"2009","journal-title":"J. Anal. At. Spectrom."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0070","first-page":"284","article-title":"Estimation of honey authenticity by multielements characteristics using inductively coupled plasma-mass spectrometry (ICP-MS) combined with chemometrics","volume":"48","author":"Chudzinska","year":"2010","journal-title":"Food Chem."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0075","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1016\/j.foodchem.2007.09.029","article-title":"Minor and trace elements in different honey types produced in Siena Country (Italy)","volume":"107","author":"Pisani","year":"2008","journal-title":"Food Chem."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0080","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.eswa.2018.08.002","article-title":"Combining elemental analysis of toenails and machine learning techniques as a non-invasive diagnostic tool for the robust classification of type-2 diabetes","volume":"115","author":"Carter","year":"2019","journal-title":"Expert Syst. Appl."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0085","doi-asserted-by":"crossref","first-page":"2197","DOI":"10.1002\/hbm.20661","article-title":"Analyzing brain networks with PCA and conditional Granger causality","volume":"30","author":"Zhou","year":"2009","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0090","doi-asserted-by":"crossref","first-page":"153","DOI":"10.12732\/ijpam.v115i1.12","article-title":"Principal component analysis for stock portfolio management","volume":"115","author":"Pasini","year":"2017","journal-title":"Int. J. Pure Appl. Math."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0095","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1023\/A:1010933404324","article-title":"Random forests","volume":"45","author":"Breiman","year":"2001","journal-title":"Mach. Learn."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0100","doi-asserted-by":"crossref","first-page":"32","DOI":"10.2202\/1544-6115.1691","article-title":"Random forests for genetic association studies","volume":"10","author":"Goldstein","year":"2011","journal-title":"Stat. Appl. Genet. Mol. Biol."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0105","doi-asserted-by":"crossref","first-page":"16164","DOI":"10.1002\/chem.201404675","article-title":"Design of enzymatically cleavable prodrugs of a potent platinum-containing anticancer agent","volume":"20","author":"Ding","year":"2014","journal-title":"Chem. Eur. J."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0110","doi-asserted-by":"crossref","first-page":"16174","DOI":"10.1002\/chem.201404845","article-title":"Redesigning the DNA-targeted chromophore in platinum-acridine anticancer agents: a structure-activity relationship study","volume":"20","author":"Pickard","year":"2014","journal-title":"Chem. Eur. J."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0115","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s12011-012-9513-7","article-title":"Are additional trace elements necessary in total parental nutrition for patients with esophageal cancer receiving cisplatin-based chemotherapy?","volume":"150","author":"Akutsu","year":"2012","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0120","doi-asserted-by":"crossref","first-page":"2683","DOI":"10.1681\/ASN.V12122683","article-title":"Manganese superoxide dismutase attenuates cisplatin-induced renal injury: importance of superoxide","volume":"12","author":"Davis","year":"2001","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0125","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1159\/000095539","article-title":"Common mechanisms in nephropathy induced by toxic metals","volume":"104","author":"Sabolic","year":"2006","journal-title":"Nephron Physiol."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0130","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1186\/1471-2164-7-142","article-title":"Centering, scaling, and transformations: improving the biological information content of metabolomics data","volume":"7","author":"van den Berg","year":"2006","journal-title":"BMC Genom."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0135","series-title":"Applied Predictive Modeling","author":"Kuhn","year":"2013"},{"key":"10.1016\/j.jtemb.2019.04.005_bib0140","first-page":"F991","article-title":"Mitochondrial alterations in cisplatin-induced acute renal failure","volume":"250","author":"Gordon","year":"1986","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.jtemb.2019.04.005_bib0145","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/0887-2333(95)00112-3","article-title":"Role of calcium in cisplatin-induced cell toxicity in rat renal cortical slices","volume":"10","author":"Zhang","year":"1996","journal-title":"Toxicol. In Vitro"}],"container-title":["Journal of Trace Elements in Medicine and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0946672X19300355?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0946672X19300355?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T19:07:42Z","timestamp":1760555262000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0946672X19300355"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":29,"alternative-id":["S0946672X19300355"],"URL":"https:\/\/doi.org\/10.1016\/j.jtemb.2019.04.005","relation":{},"ISSN":["0946-672X"],"issn-type":[{"value":"0946-672X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of platinum-based anticancer drugs on the trace element profile of liver and kidney tissue from mice","name":"articletitle","label":"Article Title"},{"value":"Journal of Trace Elements in Medicine and Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtemb.2019.04.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}]}}