{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T05:10:09Z","timestamp":1778562609560,"version":"3.51.4"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100009086","name":"Medical University Sofia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009086","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Trace Elements in Medicine and Biology"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1016\/j.jtemb.2019.126429","type":"journal-article","created":{"date-parts":[[2019,11,2]],"date-time":"2019-11-02T20:24:40Z","timestamp":1572726280000},"page":"126429","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Comparative study on the effects of salinomycin, monensin and meso-2,3-dimercaptosuccinic acid on the concentrations of lead, calcium, copper, iron and zinc in lungs and heart in lead-exposed mice"],"prefix":"10.1016","volume":"58","author":[{"given":"Juliana","family":"Ivanova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kalina","family":"Kamenova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilia","family":"Petrova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivelin","family":"Vladov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yordanka","family":"Gluhcheva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petar","family":"Dorkov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtemb.2019.126429_bib0005","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/840547","article-title":"Pb neurotoxicity: neuropsychological effects of lead toxicity","volume":"2014","author":"Mason","year":"2014","journal-title":"Biomed Res. Int."},{"issue":"2","key":"10.1016\/j.jtemb.2019.126429_bib0010","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1515\/intox-2015-0009","article-title":"Lead toxicity: a review","volume":"8","author":"Wani","year":"2015","journal-title":"Interdiscip. Toxicol."},{"issue":"11","key":"10.1016\/j.jtemb.2019.126429_bib0015","doi-asserted-by":"crossref","first-page":"737","DOI":"10.5812\/ircmj.4134","article-title":"Respiratory symptoms and pulmonary function testes in lead exposed workers","volume":"14","author":"Khazdair","year":"2012","journal-title":"Iran. Red Crescent Med. J."},{"key":"10.1016\/j.jtemb.2019.126429_bib0020","doi-asserted-by":"crossref","first-page":"2593","DOI":"10.3390\/ijerph8072593","article-title":"The protean toxicities of lead: new chapters in a familiar story","volume":"8","author":"Bellinger","year":"2011","journal-title":"Int. J. Envion. Res. Public Health"},{"key":"10.1016\/j.jtemb.2019.126429_bib0025","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1289\/ehp.9785","article-title":"Lead-exposure and cardiovascular disease \u2013 a systematic review","volume":"115","author":"Navas-Acien","year":"2007","journal-title":"Environ. Health Perspect."},{"issue":"4","key":"10.1016\/j.jtemb.2019.126429_bib0030","doi-asserted-by":"crossref","first-page":"e177","DOI":"10.1016\/S2468-2667(18)30025-2","article-title":"Low-level lead exposure and mortality in US adults: a population \u2013 based cohort study","volume":"3","author":"Lanphear","year":"2018","journal-title":"Lancet Public Health"},{"key":"10.1016\/j.jtemb.2019.126429_bib0035","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.jtemb.2016.03.013","article-title":"A review of pitfalls and progress in chelation treatment of metal poisonings","volume":"38","author":"Andersen","year":"2016","journal-title":"J. Trace Elem. Med. Biol."},{"issue":"4","key":"10.1016\/j.jtemb.2019.126429_bib0040","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1289\/ehp.8279","article-title":"Monensin improves the effectiveness of meso-dimercaptosuccinate when used to treat lead intoxication in rats","volume":"114","author":"Hamidinia","year":"2006","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.jtemb.2019.126429_bib0045","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.jtemb.2015.08.003","article-title":"Comparative assessment of the effects of salinomycin and monensin on the biodistribution of lead and some essential metal ions in mice, subjected to subacute lead intoxication","volume":"33","author":"Ivanova","year":"2016","journal-title":"J. Trace Elem. Med. Biol."},{"key":"10.1016\/j.jtemb.2019.126429_bib0050","first-page":"852","article-title":"Crystal structure and spectral properties of new Cd(II) and Hg(II) complexes of monensic acid with different coordination mode of ligand","volume":"8","author":"Ivanova","year":"2010","journal-title":"Cent. Eur. J. Chem."},{"key":"10.1016\/j.jtemb.2019.126429_bib0055","first-page":"51","article-title":"Synthesis, spectral properties, antibacterialand antitumor activity of salinomycin complexes with Co(II), Ni(II), Cu(II) and Zn(II) transition metal ions","volume":"6","author":"Ivanova","year":"2012","journal-title":"J. Chem. Chem. Eng."},{"issue":"6","key":"10.1016\/j.jtemb.2019.126429_bib0060","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.1000412","article-title":"Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research","volume":"8","author":"Kilkenny","year":"2010","journal-title":"PLoS Biol."},{"key":"10.1016\/j.jtemb.2019.126429_bib0065","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1080\/09593330903055643","article-title":"Lead distribution in blood and organs of mice exposed to lead by vein injection","volume":"30","author":"Sun","year":"2009","journal-title":"Environ. Technol."},{"issue":"5","key":"10.1016\/j.jtemb.2019.126429_bib0070","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0096900","article-title":"Chronic lead exposure increases blood pressure and myocardial contractility in rats","volume":"9","author":"Fioresi","year":"2014","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.jtemb.2019.126429_bib0075","doi-asserted-by":"crossref","first-page":"47","DOI":"10.2478\/v10102-012-0009-2","article-title":"Toxicity of lead: a review with recent updates","volume":"5","author":"Flora","year":"2012","journal-title":"Interdisc. Toxicol."},{"key":"10.1016\/j.jtemb.2019.126429_bib0080","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1177\/0960327111405865","article-title":"Effects of lead and\/or cadmium on the distribution patterns of some essential trace elements in immature female rats","volume":"30","author":"Wang","year":"2011","journal-title":"Hum. Exp. Toxicol."},{"issue":"2","key":"10.1016\/j.jtemb.2019.126429_bib0085","first-page":"13","article-title":"Molecular mechanism of lead toxicity","volume":"95","author":"Szymanski","year":"2014","journal-title":"J. Biotech. Comput. Biol. Bionanotechnol."},{"key":"10.1016\/j.jtemb.2019.126429_bib0090","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1093\/toxsci\/62.2.321","article-title":"Skeletal effect of developmental lead exposure inrats","volume":"62","author":"Ronis","year":"2001","journal-title":"Toxicol. Sci."},{"issue":"2","key":"10.1016\/j.jtemb.2019.126429_bib0095","first-page":"21","article-title":"Toxic effect of lead on kidney function in rat wistar","volume":"4","author":"Missoun","year":"2010","journal-title":"Afr. J. Biochem. Res."},{"key":"10.1016\/j.jtemb.2019.126429_bib0100","doi-asserted-by":"crossref","first-page":"H454","DOI":"10.1152\/ajpheart.00158.2008","article-title":"Mechanisms of lead-induced hypertension and cardiovascular disease","volume":"295","author":"Vaziri","year":"2008","journal-title":"Am. J. Physiol. Heart Cir. Physiol."},{"key":"10.1016\/j.jtemb.2019.126429_bib0105","first-page":"412","article-title":"Experimental investigations on the concentration induced by lead in arterial smooth muscle","volume":"41","author":"Favalli","year":"1977","journal-title":"Acta Pharmacol. Toxicol. (Copenh)"},{"key":"10.1016\/j.jtemb.2019.126429_bib0110","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/0300-483X(77)90022-1","article-title":"Experimental investigations on the contraction induced by lead in arterial smooth muscle","volume":"8","author":"Piccinini","year":"1977","journal-title":"Toxicology"},{"key":"10.1016\/j.jtemb.2019.126429_bib0115","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0300-483X(94)03003-K","article-title":"Lead acetate-induced contraction in rabbit mesenteric artery: interaction with calcium and protein kinase C","volume":"99","author":"Watts","year":"1995","journal-title":"Toxicology"},{"issue":"1","key":"10.1016\/j.jtemb.2019.126429_bib0120","doi-asserted-by":"crossref","first-page":"15","DOI":"10.4103\/0019-5278.16036","article-title":"Decreased total andionized calcium levels and haematological indices in occupational lead exposures evidence of the endocrine disruptive effect of lead","volume":"9","author":"Anetor","year":"2005","journal-title":"Indian J. Occup. Environ. Med."},{"issue":"5","key":"10.1016\/j.jtemb.2019.126429_bib0125","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1007\/BF02256119","article-title":"Calcium overload and cardiac function","volume":"11","author":"Vassalle","year":"2004","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.jtemb.2019.126429_bib0130","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/s10534-009-9269-5","article-title":"First solid state alkaline-earth complexes of monensic acid A (MonH): crystalstructure of [M(Mon)2(H2O)2] (M = Mg, Ca), spectral properties and cytotoxicityagainst aerobic Gram-positive bacteria","volume":"23","author":"Pantcheva","year":"2010","journal-title":"Biometals"},{"key":"10.1016\/j.jtemb.2019.126429_bib0135","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1177\/0960327109102365","article-title":"Protective effect of N-acetylcysteine on experimental chronic cadmium nephrotoxicity in immature female rats","volume":"28","author":"Wang","year":"2009","journal-title":"Hum. Exp. Toxicol."},{"key":"10.1016\/j.jtemb.2019.126429_bib0140","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1177\/0960327109357270","article-title":"Protective effect ofN-acetylcysteine on experimental chronic lead nephrotoxicity in immature female rats","volume":"29","author":"Wang","year":"2010","journal-title":"Hum. Exp. Toxicol."},{"key":"10.1016\/j.jtemb.2019.126429_bib0145","first-page":"64","article-title":"Effect of lead toxicity on mineral metabolism and immunological factors inrats","volume":"39","author":"Taha","year":"2013","journal-title":"Alexandria J. Vet. Sci."},{"key":"10.1016\/j.jtemb.2019.126429_bib0150","first-page":"291","article-title":"Activity of superoxidedismutase and catalase in people protractedly exposed to lead compounds","volume":"11","author":"Kasperczyk","year":"2004","journal-title":"Ann. Agric. Environ.Med."},{"key":"10.1016\/j.jtemb.2019.126429_bib0155","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/s10522-012-9380-9","article-title":"Lead-induced cardiac and hematological alterations in aging Wistar male rats: alleviating effects of nutrient metal mixture","volume":"13","author":"Basha","year":"2012","journal-title":"Biogerontology"},{"key":"10.1016\/j.jtemb.2019.126429_bib0160","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.jtemb.2010.01.002","article-title":"Effects of subchronic low-level lead exposure on the homeostasis of copper and zinc on rat tissues","volume":"24","author":"Ademuyiwa","year":"2010","journal-title":"J. Trace Elem. Med. Biol."},{"issue":"7","key":"10.1016\/j.jtemb.2019.126429_bib0165","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.3390\/ijerph7072745","article-title":"Chelation in metal intoxication","volume":"7","author":"Flora","year":"2010","journal-title":"Int. J. Environ. Res. Public Health"},{"issue":"13","key":"10.1016\/j.jtemb.2019.126429_bib0170","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.jacc.2010.03.083","article-title":"Iron overload cardiomyopathy: better understanding of an increasing disorder","volume":"56","author":"Gujja","year":"2010","journal-title":"J. Amer. Coll. Cardiol."}],"container-title":["Journal of Trace Elements in Medicine and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0946672X19304304?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0946672X19304304?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T04:20:39Z","timestamp":1778559639000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0946672X19304304"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":34,"alternative-id":["S0946672X19304304"],"URL":"https:\/\/doi.org\/10.1016\/j.jtemb.2019.126429","relation":{},"ISSN":["0946-672X"],"issn-type":[{"value":"0946-672X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparative study on the effects of salinomycin, monensin and meso-2,3-dimercaptosuccinic acid on the concentrations of lead, calcium, copper, iron and zinc in lungs and heart in lead-exposed mice","name":"articletitle","label":"Article Title"},{"value":"Journal of Trace Elements in Medicine and Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtemb.2019.126429","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"126429"}}