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Braz. Chem. Soc."},{"key":"10.1016\/j.jtemb.2020.126508_bib0450","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/0304-4165(86)90230-8","article-title":"Vanadium complexes of transferrin and ferritin in the rat","volume":"884","author":"Chasteen","year":"1986","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.jtemb.2020.126508_bib0455","doi-asserted-by":"crossref","first-page":"5747","DOI":"10.1021\/ic802287s","article-title":"On the transport of vanadium in blood serum","volume":"48","author":"Sanna","year":"2009","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jtemb.2020.126508_bib0460","doi-asserted-by":"crossref","first-page":"2279","DOI":"10.1093\/jn\/112.12.2279","article-title":"Balance and tissue distribution of vanadium after short-term ingestion of vanadate","volume":"112","author":"Bogden","year":"1982","journal-title":"J. Nutr."},{"key":"10.1016\/j.jtemb.2020.126508_bib0465","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1046\/j.1472-8206.2001.00043.x","article-title":"Vanadium pharmacokinetics and oral bioavailability upon single-dose administration of vanadyl sulfate to rats","volume":"15","author":"Azay","year":"2001","journal-title":"Fundam. Clin. Pharmacol."},{"key":"10.1016\/j.jtemb.2020.126508_bib0470","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1684\/mrh.2011.0293","article-title":"Bioavailability, tissue distribution and hypoglycaemic effect of vanadium in magnesium-deficient rats","volume":"24","author":"S\u00e1nchez","year":"2011","journal-title":"Magnes. Res."},{"key":"10.1016\/j.jtemb.2020.126508_bib0475","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1016\/j.febslet.2008.04.057","article-title":"The antioxidant properties of serum albumin","volume":"582","author":"Roche","year":"2008","journal-title":"FEBS Lett."},{"key":"10.1016\/j.jtemb.2020.126508_bib0480","first-page":"231","article-title":"Vanadium-protein interactions","volume":"31","author":"Chasteen","year":"1995"},{"key":"10.1016\/j.jtemb.2020.126508_bib0485","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1002\/asia.201700469","article-title":"Interaction of [VIVO(acac)2] with human serum transferrin and albumin","volume":"12","author":"Correia","year":"2017","journal-title":"Chem. Asian J."},{"key":"10.1016\/j.jtemb.2020.126508_bib0490","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0162-0134(84)80029-X","article-title":"Binding of vanadate to human serum transferrin","volume":"22","author":"Harris","year":"1984","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jtemb.2020.126508_bib0495","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.jinorgbio.2017.12.012","article-title":"Binding of vanadium to human serum transferrin - voltammetric and spectrometric studies","volume":"180","author":"Azevedo","year":"2018","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jtemb.2020.126508_bib0500","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.ica.2013.11.025","article-title":"New insights on vanadium binding to human serum transferrin","volume":"420","author":"Pessoa","year":"2014","journal-title":"Inorg. Chim. Acta Rev."},{"key":"10.1016\/j.jtemb.2020.126508_bib0505","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/s12011-018-1540-6","article-title":"Vanadium in biological action: chemical, pharmacological aspects, and metabolic implications in diabetic mellitus","volume":"188","author":"Trevi\u00f1o","year":"2019","journal-title":"Biol. Trace Elem. 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Chem."},{"key":"10.1016\/j.jtemb.2020.126508_bib0530","doi-asserted-by":"crossref","first-page":"11749","DOI":"10.1039\/c3dt50457c","article-title":"The future of\/for vanadium","volume":"42","author":"Rehder","year":"2013","journal-title":"Dalton Trans."},{"key":"10.1016\/j.jtemb.2020.126508_bib0535","first-page":"317","article-title":"Vanadium detoxification","volume":"31","author":"Baran","year":"1998"},{"key":"10.1016\/j.jtemb.2020.126508_bib0540","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1007\/s00775-002-0376-9","article-title":"Fractionation of vanadium complexes in serum, packed cells and tissues of Wistar rats by means of gel filtration and anion-exchange chromatography","volume":"7","author":"De Cremer","year":"2002","journal-title":"J. Biol. Inorg. 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Sci."},{"key":"10.1016\/j.jtemb.2020.126508_bib0580","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1098\/rsif.2010.0118.focus","article-title":"Titanum oral implants: surface characteristics, interface biology and clinical outcome","volume":"7","author":"Palmquist","year":"2010","journal-title":"J. R. Soc. Interface"},{"key":"10.1016\/j.jtemb.2020.126508_bib0585","series-title":"Recent Advances in Arthroplasty","first-page":"149","article-title":"Titanium as a biomaterial for implants","author":"Oldani","year":"2012"},{"key":"10.1016\/j.jtemb.2020.126508_bib0590","doi-asserted-by":"crossref","first-page":"550","DOI":"10.3109\/15563650.2013.818682","article-title":"Vanadium release in whole blood, serum and urine of patients implanted with a titanium alloy hip prosthesis","volume":"51","author":"Catalani","year":"2013","journal-title":"Clin. Toxicol."},{"key":"10.1016\/j.jtemb.2020.126508_bib0595","series-title":"Biomaterials for Implants and Scaffolds","first-page":"107","article-title":"Implant surface modifications and osseointegration","author":"Chakravorty","year":"2017"},{"key":"10.1016\/j.jtemb.2020.126508_bib0600","first-page":"65","article-title":"Bioactive antimicrobial coatings for implantable medical devices formed by plasma electrolytic oxidation","volume":"29","author":"Dzhurinskiy","year":"2018","journal-title":"Metal Forming"},{"key":"10.1016\/j.jtemb.2020.126508_bib0605","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/S0925-9635(03)00018-9","article-title":"Diamond-like carbon coatings as biocompatible materials \u2013 an overview","volume":"12","author":"Grill","year":"2003","journal-title":"Diam. Realt. 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Med."},{"key":"10.1016\/j.jtemb.2020.126508_bib0665","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/j.jscs.2013.07.001","article-title":"Synthesis, spectral characterization, electrochemical, anti-microbial, DNA binding and cleavage studies of new binuclear Schiff base metal(II) complexes derived from o-hydroxyacetophenone","volume":"20","author":"Jayaseelan","year":"2016","journal-title":"J. Saudi Chem. Soc."},{"key":"10.1016\/j.jtemb.2020.126508_bib0670","first-page":"1","article-title":"In vitro and in vivo antifungal activities and mechanism of heteropolytungstates against Candida species","volume":"7","author":"Li","year":"2017","journal-title":"Sci. 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Sci."},{"key":"10.1016\/j.jtemb.2020.126508_bib0740","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.tcb.2019.02.004","article-title":"Regulation and function of mitochondria-lysosome membrane contact sites in cellular homeostasis","volume":"29","author":"Wong","year":"2019","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.jtemb.2020.126508_bib0745","doi-asserted-by":"crossref","first-page":"195","DOI":"10.18388\/abp.2012_2138","article-title":"Biochemical and medical importance of vanadium compounds","volume":"59","author":"Korbecki","year":"2012","journal-title":"Acta Biochim. Pol."},{"key":"10.1016\/j.jtemb.2020.126508_bib0750","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.carbpol.2017.06.027","article-title":"Toxicity of native and oxovanadium (IV\/V) galactomannan complexes on HepG2 cells is related to impairment of mitochondrial functions","volume":"173","author":"Cunha-de Padua","year":"2017","journal-title":"Carbohydr. 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Sci."},{"key":"10.1016\/j.jtemb.2020.126508_bib0825","doi-asserted-by":"crossref","first-page":"60324","DOI":"10.18632\/oncotarget.19454","article-title":"Selective cytotoxicity of vanadium complexes on human pancreatic ductal adenocarcinoma cell line by inducing necroptosis, apoptosis and mitotic catastrophe process","volume":"8","author":"Kowalski","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.jtemb.2020.126508_bib0830","doi-asserted-by":"crossref","first-page":"16276","DOI":"10.1039\/C7DT03585C","article-title":"Exploring the effect of substituent in the hydrazone ligand of a family of u-oxidodivanadium(V) hydrazone complexes on structure, DNA binding and anti-cancer activity","volume":"46","author":"Patra","year":"2017","journal-title":"Dalton Trans."},{"key":"10.1016\/j.jtemb.2020.126508_bib0835","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1080\/00958972.2018.1461848","article-title":"Anticancer diaminotris(phenolato) vanadium(V) complexes: ligand-metal interplay","volume":"71","author":"Reytman","year":"2018","journal-title":"J. Coord. Chem."},{"key":"10.1016\/j.jtemb.2020.126508_bib0840","first-page":"251","article-title":"Health benefits of vanadium and its potential as an anticancer agent","volume":"18","author":"Crans","year":"2018"},{"key":"10.1016\/j.jtemb.2020.126508_bib0845","first-page":"203","article-title":"Rola bia\u0142kowej fosfatazy tyrozynowej 1B (PTP-1B) w rozwoju insulinooporno\u015bci","volume":"59","author":"Bodu\u0142a","year":"2005","journal-title":"Post\u0119py Hig. Med. Do\u015bw."},{"key":"10.1016\/j.jtemb.2020.126508_bib0850","doi-asserted-by":"crossref","first-page":"5416","DOI":"10.1021\/ic048331q","article-title":"Aqueous Chemistry of the VanadiumIII (VIII) and the VIII\u2212Dipicolinate systems and a comparison of the effect of three oxidation states of vanadium compounds on diabetic hyperglycemia in rats","volume":"44","author":"Buglyo","year":"2005","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jtemb.2020.126508_bib0855","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1023\/A:1015558328757","article-title":"Vanadium increases GLUT4 in diabetic rat skeletal muscle","volume":"233","author":"Mohammad","year":"2002","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.jtemb.2020.126508_bib0860","first-page":"60","article-title":"Insulino-mimetyczne w\u0142a\u015bciwo\u015bci zwi\u0105zk\u00f3w wanadu","volume":"62","author":"Korbecki","year":"2016","journal-title":"Post\u0119py Biochem."},{"key":"10.1016\/j.jtemb.2020.126508_bib0865","first-page":"361","article-title":"Pochodne wanadu jako zwi\u0105zki o istotnym znaczeniu biologicznym","volume":"36","author":"Kordowiak","year":"2009","journal-title":"Cz\u0119\u015b\u0107 I. Dzia\u0142anie przeciwcukrzycowe, Post\u0119py Biol. Kom."},{"key":"10.1016\/j.jtemb.2020.126508_bib0870","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.fct.2016.07.005","article-title":"Vanadium compounds for the treatment of human diabetes mellitus: a scientific curiosity? A review of thirty years of research","volume":"95","author":"Domingo","year":"2016","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.jtemb.2020.126508_bib0875","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/0024-3205(79)90138-3","article-title":"Effects of vanadium on glucose metabolism in vitro","volume":"25","author":"Tolman","year":"1979","journal-title":"Life Sci."},{"key":"10.1016\/j.jtemb.2020.126508_bib0880","doi-asserted-by":"crossref","first-page":"5306","DOI":"10.1016\/S0021-9258(19)70787-X","article-title":"The insulin-mimetic effects of vanadate in isolated rat adipocytes. Dissociation from effects of vanadate as a (Na+-K+)ATPase inhibitor","volume":"255","author":"Dubyak","year":"1980","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jtemb.2020.126508_bib0885","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1038\/284556a0","article-title":"Insulin-like stimulation of glucose oxidation in rat adipocytes by vanadyl (IV) ions","volume":"284","author":"Shechter","year":"1980","journal-title":"Nature"},{"key":"10.1016\/j.jtemb.2020.126508_bib0890","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1126\/science.3156405","article-title":"Effect of vanadate on elevate blood glucose and decreased cardiac performance of diabetic rats","volume":"227","author":"Heyliger","year":"1985","journal-title":"Science"},{"key":"10.1016\/j.jtemb.2020.126508_bib0895","doi-asserted-by":"crossref","first-page":"6658","DOI":"10.1016\/S0021-9258(18)48292-0","article-title":"Oral administration of vanadate normalizes blood glucose levels in streptozotocin-treated rats. Characterization and mode of action","volume":"262","author":"Meyerovitch","year":"1987","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jtemb.2020.126508_bib0900","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.jinorgbio.2008.12.003","article-title":"Vanadium treatment of type 2 diabetes: a view to the future","volume":"103","author":"Thompson","year":"2009","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.jtemb.2020.126508_bib0905","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1016\/j.jinorgbio.2006.08.016","article-title":"Vanadium in diabetes: 100 years from phase 0 to phase I","volume":"100","author":"Thompson","year":"2006","journal-title":"J. Inorg. 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Invest."},{"key":"10.1016\/j.jtemb.2020.126508_bib0940","doi-asserted-by":"crossref","first-page":"659","DOI":"10.2337\/diab.45.5.659","article-title":"Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects","volume":"45","author":"Halberstam","year":"1996","journal-title":"Diabetes"},{"key":"10.1016\/j.jtemb.2020.126508_bib0945","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1016\/S0026-0495(96)90013-X","article-title":"Effects of vanadyl sulfate on carbohydrate and lipid metabolism in patients with non-insulin-dependent diabetes mellitus","volume":"45","author":"Boden","year":"1996","journal-title":"Metabolism"},{"key":"10.1016\/j.jtemb.2020.126508_bib0950","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/BF01075941","article-title":"In vivo and in vitro studies of vanadate in human and rodent diabetes mellitus","volume":"153","author":"Goldfine","year":"1995","journal-title":"Mol. Cell. 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