{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T22:44:26Z","timestamp":1793054666157,"version":"4.5.0"},"reference-count":102,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003443","name":"Ministry of Education and Science of the Russian Federation","doi-asserted-by":"publisher","award":["075\u201315-2022\u2013304"],"award-info":[{"award-number":["075\u201315-2022\u2013304"]}],"id":[{"id":"10.13039\/501100003443","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Trace Elements in Medicine and Biology"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.jtemb.2023.127241","type":"journal-article","created":{"date-parts":[[2023,6,12]],"date-time":"2023-06-12T11:35:43Z","timestamp":1686569743000},"page":"127241","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"special_numbering":"C","title":["Medical application of laser-induced breakdown spectroscopy (LIBS) for assessment of trace element and mineral in biosamples: Laboratory and clinical validity of the method"],"prefix":"10.1016","volume":"79","author":[{"given":"Anatoly V.","family":"Skalny","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana V.","family":"Korobeinikova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Aschner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oksana V.","family":"Baranova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanouil G.","family":"Barbounis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aristides","family":"Tsatsakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexey A.","family":"Tinkov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtemb.2023.127241_bib1","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1007\/s10103-014-1549-9","article-title":"Importance of laser-induced breakdown spectroscopy for hard tissues (bone, teeth) and other calcified tissue materials","volume":"30","author":"Singh","year":"2015","journal-title":"Lasers Med. Sci."},{"issue":"2021","key":"10.1016\/j.jtemb.2023.127241_bib2","first-page":"1","article-title":"Development in the application of laser-induced breakdown spectroscopy in recent years: a review","volume":"16","author":"Guo","year":"2021","journal-title":"Front. Phys."},{"key":"10.1016\/j.jtemb.2023.127241_bib3","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/3887038","article-title":"Laser-induced breakdown spectroscopy (LIBS) for trace element detection: a review","author":"Khan","year":"2022","journal-title":"J. Spectrosc."},{"key":"10.1016\/j.jtemb.2023.127241_bib4","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1366\/11-06574","article-title":"Laser-induced breakdown spectroscopy (LIBS), part II: review of instrumental and methodological approaches to material analysis and applications to different fields","volume":"66","author":"Hahn","year":"2022","journal-title":"Appl. Spectrosc."},{"key":"10.1016\/j.jtemb.2023.127241_bib5","article-title":"Laser induced breakdown spectroscopy methods and applications: a comprehensive review","volume":"170","author":"Shah","year":"2020","journal-title":"Radiat. Phys. Chem."},{"key":"10.1016\/j.jtemb.2023.127241_bib6","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.sab.2018.11.006","article-title":"Laser-induced breakdown spectroscopy for human and animal health: a review","volume":"152","author":"Gaudiuso","year":"2019","journal-title":"Spectrochim. Acta B: . Spectrosc."},{"key":"10.1016\/j.jtemb.2023.127241_bib7","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.surfrep.2012.09.001","article-title":"Trace elemental analysis by laser-induced breakdown spectroscopy \u2014 biological applications","volume":"67","author":"Kaiser","year":"2012","journal-title":"Surf. Sci. Rep."},{"key":"10.1016\/j.jtemb.2023.127241_bib8","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1080\/05704928.2020.1739063","article-title":"Current trends in laser-induced breakdown spectroscopy: a tutorial review","volume":"56","author":"Fernandes Andrade","year":"2021","journal-title":"Appl. Spectrosc. Rev."},{"key":"10.1016\/j.jtemb.2023.127241_bib9","doi-asserted-by":"crossref","first-page":"6438","DOI":"10.3390\/molecules27196438","article-title":"Electrolyte analysis in blood serum by laser-induced breakdown spectroscopy using a portable laser","volume":"27","author":"Feng","year":"2022","journal-title":"Molecules"},{"key":"10.1016\/j.jtemb.2023.127241_bib10","doi-asserted-by":"crossref","first-page":"2224","DOI":"10.1039\/D0JA00164C","article-title":"Quantitative trace elemental analysis by laser-induced breakdown spectroscopy with dried droplet pretreatment","volume":"35","author":"Liu","year":"2020","journal-title":"J. Anal. At. Spectrom."},{"key":"10.1016\/j.jtemb.2023.127241_bib11","doi-asserted-by":"crossref","first-page":"2807","DOI":"10.1021\/acs.analchem.6b03766","article-title":"Melted paraffin wax as an innovative liquid and solid extractant for elemental analysis by laser-induced breakdown spectroscopy","volume":"89","author":"Papai","year":"2017","journal-title":"Anal. Chem."},{"key":"10.1016\/j.jtemb.2023.127241_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.optlastec.2021.107622","article-title":"Elemental analysis of liquid samples by laser induced breakdown spectroscopy (LIBS): challenges and potential experimental strategies","volume":"147","author":"Keerthi","year":"2022","journal-title":"Opt. Laser Technol."},{"key":"10.1016\/j.jtemb.2023.127241_bib13","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.talanta.2015.11.031","article-title":"Development and validation of a laser-induced breakdown spectroscopic method for ultra-trace determination of Cu, Mn, Cd and Pb metals in aqueous droplets after drying","volume":"149","author":"Aras","year":"2016","journal-title":"Talanta"},{"key":"10.1016\/j.jtemb.2023.127241_bib14","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.ccr.2017.12.006","article-title":"Elemental imaging using laser-induced breakdown spectroscopy: a new and promising approach for biological and medical applications","volume":"358","author":"Busser","year":"2018","journal-title":"Coord. Chem. Rev."},{"key":"10.1016\/j.jtemb.2023.127241_bib15","doi-asserted-by":"crossref","first-page":"29936","DOI":"10.1038\/srep29936","article-title":"3D imaging of nanoparticle distribution in biological tissue by laser-induced breakdown spectroscopy","volume":"6","author":"Gimenez","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jtemb.2023.127241_bib16","series-title":"Laser-Induced Breakdown Spectroscopy in Biological, Forensic and Materials Sciences","first-page":"139","article-title":"Imaging of biological tissues","author":"Po\u0159\u00edzka","year":"2022"},{"key":"10.1016\/j.jtemb.2023.127241_bib17","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1021\/acs.analchem.2c04910","article-title":"Laser-induced breakdown spectroscopy imaging for material and biomedical applications: recent advances and future perspectives","volume":"95","author":"Gardette","year":"2023","journal-title":"Anal. Chem."},{"key":"10.1016\/j.jtemb.2023.127241_bib18","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1080\/05704928.2020.1791151","article-title":"A brief review of laser-induced breakdown spectroscopy for human and animal soft tissues: pathological diagnosis and physiological detection","volume":"56","author":"Wang","year":"2021","journal-title":"Appl. Spectrosc. Rev."},{"key":"10.1016\/j.jtemb.2023.127241_bib19","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1007\/s10103-011-0921-2","article-title":"Prospects for laser-induced breakdown spectroscopy for biomedical applications: a review","volume":"26","author":"Singh","year":"2011","journal-title":"Lasers Med Sci."},{"key":"10.1016\/j.jtemb.2023.127241_bib20","article-title":"Laser-induced breakdown spectroscopy in dentistry","author":"Akarslan","year":"2022","journal-title":"Spectrosc. Tech. Dent. Appl."},{"key":"10.1016\/j.jtemb.2023.127241_bib21","article-title":"Validity of laser induced breakdown spectroscopy (LIBS) in determining age and sex from tooth specimens","volume":"8","author":"Unnikrishnan","year":"2022","journal-title":"Heliyon"},{"key":"10.1016\/j.jtemb.2023.127241_bib22","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1007\/s10103-015-1790-x","article-title":"Laser-induced breakdown spectroscopy analysis of human deciduous teeth samples","volume":"30","author":"Khalid","year":"2015","journal-title":"Lasers Med. Sci."},{"key":"10.1016\/j.jtemb.2023.127241_bib23","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s40009-018-0735-x","article-title":"Laser-induced breakdown spectroscopy coupled with PCA study of human tooth","volume":"42","author":"Pathak","year":"2019","journal-title":"Natl. Acad. Sci. Lett."},{"key":"10.1016\/j.jtemb.2023.127241_bib24","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1007\/s00414-014-1131-9","article-title":"Spatial distribution analysis of strontium in human teeth by laser-induced breakdown spectroscopy: application to diagnosis of seawater drowning","volume":"129","author":"Fortes","year":"2015","journal-title":"Int. J. Leg. Med."},{"key":"10.1016\/j.jtemb.2023.127241_bib25","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1364\/AO.54.000123","article-title":"Discrimination of healthy and carious teeth using laser-induced breakdown spectroscopy and partial least square discriminant analysis","volume":"54","author":"Gazmeh","year":"2015","journal-title":"Appl. Opt."},{"key":"10.1016\/j.jtemb.2023.127241_bib26","doi-asserted-by":"crossref","unstructured":"S.N. M. Yassin, S.N. M. Hashim, M.I.M. Salim, R.H. Al Ashwal, A.A. Wahab, M. Sahalan,., L.K. Wee, Feasibility of using saliva samples and laser-induced breakdown spectroscopy for dental screening during pandemic. In: Proceedings of the Kuala Lumpur International Conference on Biomedical Engineering, Springer, Cham., 2022 pp. 501\u2013509.","DOI":"10.1007\/978-3-030-90724-2_54"},{"key":"10.1016\/j.jtemb.2023.127241_bib27","doi-asserted-by":"crossref","first-page":"7342","DOI":"10.1364\/AO.54.007342","article-title":"Detection of toxic elements using laser-induced breakdown spectroscopy in smokers\u2019 and nonsmokers\u2019 teeth and investigation of periodontal parameters","volume":"54","author":"Alhasmi","year":"2015","journal-title":"Appl. Opt."},{"key":"10.1016\/j.jtemb.2023.127241_bib28","series-title":"Proceedings of the High Capacity Optical Networks and Emerging\/Enabling Technologies","first-page":"94","article-title":"Investigation of periodontal parameters and toxic elements in teeth due to smoking using laser induced breakdown spectroscopy","author":"Alhasmi","year":"2013"},{"key":"10.1016\/j.jtemb.2023.127241_bib29","first-page":"67","article-title":"Qualitative analysis of teeth and evaluation of amalgam elements penetration into dental matrix using laser induced breakdown spectroscopy","volume":"6","author":"Gazmeh","year":"2015","journal-title":"J. Lasers Med. Sci."},{"key":"10.1016\/j.jtemb.2023.127241_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.physb.2020.412495","article-title":"Rapid elemental analysis of human teeth using laser induced breakdown spectroscopy","volume":"602","author":"Batool","year":"2021","journal-title":"Phys. B: Condens. Matter"},{"key":"10.1016\/j.jtemb.2023.127241_bib31","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1002\/jbio.201600153","article-title":"The differentiation of oral soft- and hard tissues using laser induced breakdown spectroscopy \u2013 a prospect for tissue specific laser surgery","volume":"10","author":"Rohde","year":"2017","journal-title":"J. Biophotonics"},{"key":"10.1016\/j.jtemb.2023.127241_bib32","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1366\/000370210790918328","article-title":"Laser-induced breakdown spectroscopy microanalysis of trace elements in Homo sapiens teeth","volume":"64","author":"Alvira","year":"2010","journal-title":"Appl. Spectrosc."},{"key":"10.1016\/j.jtemb.2023.127241_bib33","article-title":"The association of tooth lead content in ancient Egyptians and contemporary with dental health factors via LIBS technique","volume":"11","author":"El-Tayeb","year":"2014","journal-title":"Life Sci. J."},{"key":"10.1016\/j.jtemb.2023.127241_bib34","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.sab.2014.07.010","article-title":"Effect of the wavelength on laser induced breakdown spectrometric analysis of archaeological bone","volume":"101","author":"Kasem","year":"2014","journal-title":"Spectrochim. Acta B: . Spectrosc."},{"key":"10.1016\/j.jtemb.2023.127241_bib35","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1039\/c1ja10057b","article-title":"Influence of biological degradation and environmental effects on the interpretation of archeological bone samples with laser-induced breakdown spectroscopy","volume":"26","author":"Kasem","year":"2011","journal-title":"J. Anal. At. Spectrom."},{"key":"10.1016\/j.jtemb.2023.127241_bib36","article-title":"Application of laser-induced breakdown spectroscopy and neural networks on archaeological human bones for the discrimination of distinct individuals","volume":"35","author":"Siozos","year":"2021","journal-title":"J. Archaeol. Sci.: Rep."},{"key":"10.1016\/j.jtemb.2023.127241_bib37","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.sab.2014.07.008","article-title":"Discrimination of human bodies from bones and teeth remains by laser induced breakdown spectroscopy and neural networks","volume":"101","author":"Moncayo","year":"2014","journal-title":"Spectrochim. Acta B: At. Spectrosc."},{"key":"10.1016\/j.jtemb.2023.127241_bib38","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/281056","article-title":"Reconstructing ancient Egyptian diet through bone elemental analysis using LIBS (Qubbet el Hawa Cemetery)","volume":"2015","author":"Al-Khafif","year":"2015","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.jtemb.2023.127241_bib39","doi-asserted-by":"crossref","first-page":"4013","DOI":"10.1364\/BOE.5.004013","article-title":"Laser induced breakdown spectroscopy for bone and cartilage differentiation-ex vivo study as a prospect for a laser surgery feedback mechanism","volume":"5","author":"Mehari","year":"2014","journal-title":"Biomed. Opt. Express"},{"key":"10.1016\/j.jtemb.2023.127241_bib40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2016\/8205479","article-title":"Influence of lead on the interpretation of bone samples with laser-induced breakdown spectroscopy","volume":"4","author":"Shahedi","year":"2016","journal-title":"J. Spectrosc."},{"key":"10.1016\/j.jtemb.2023.127241_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijleo.2021.167067","article-title":"Quantitative analysis of mineral elements in hair and nails using calibration-free laser-induced breakdown spectroscopy","volume":"242","author":"Zhang","year":"2021","journal-title":"Optik"},{"key":"10.1016\/j.jtemb.2023.127241_bib42","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.talanta.2018.03.057","article-title":"Qualitative and quantitative analysis of human nails to find correlation between nutrients and vitamin D deficiency using LIBS and ICP-AES","volume":"185","author":"Almessiere","year":"2018","journal-title":"Talanta"},{"key":"10.1016\/j.jtemb.2023.127241_bib43","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1177\/0003702816687568","article-title":"Determination of the zinc concentration in human fingernails using laser-induced breakdown spectroscopy","volume":"71","author":"Riberdy","year":"2017","journal-title":"Appl. Spectrosc."},{"key":"10.1016\/j.jtemb.2023.127241_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.sab.2019.105732","article-title":"Matrix-matched calibration material for zinc analysis of human nails by laser-induced breakdown spectroscopy","volume":"163","author":"Martinez","year":"2020","journal-title":"Spectrochim. Acta B: At. Spectrosc."},{"key":"10.1016\/j.jtemb.2023.127241_bib45","doi-asserted-by":"crossref","first-page":"75","DOI":"10.17576\/jsm-2017-4601-10","article-title":"Analysing human nails composition by using laser induced breakdown spectroscopy","volume":"46","author":"Harun","year":"2017","journal-title":"Sains Malays."},{"key":"10.1016\/j.jtemb.2023.127241_bib46","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s10103-010-0821-x","article-title":"Quantitative analysis of pathological nails using laser-induced breakdown spectroscopy (LIBS) technique","volume":"26","author":"Hamzaoui","year":"2011","journal-title":"Lasers Med. Sci."},{"key":"10.1016\/j.jtemb.2023.127241_bib47","doi-asserted-by":"crossref","DOI":"10.1063\/1.4747934","article-title":"A study of association between fingernail elements and osteoporosis by laser-induced breakdown spectroscopy","volume":"112","author":"Bahreini","year":"2012","journal-title":"J. Appl. Phys."},{"key":"10.1016\/j.jtemb.2023.127241_bib48","doi-asserted-by":"crossref","DOI":"10.1117\/1.JBO.18.10.107006","article-title":"Discrimination of patients with diabetes mellitus and healthy subjects based on laser-induced breakdown spectroscopy of their fingernails","volume":"18","author":"Bahreini","year":"2013","journal-title":"J. Biomed. Opt."},{"key":"10.1016\/j.jtemb.2023.127241_bib49","first-page":"127","article-title":"Possibility of thyroidism diagnosis by laser induced breakdown spectroscopy of human fingernail","volume":"3","author":"Bahreini","year":"2012","journal-title":"J. Lasers Med. Sci."},{"key":"10.1016\/j.jtemb.2023.127241_bib50","first-page":"121","article-title":"Laser induced breakdown spectroscopy coupled with neural networks for the identification of fingernails of smokers and non-smokers","author":"Sucho\u0148ov\u00e1","year":"2014","journal-title":"WDS'14 Proc. Contrib. Pap. - Phys."},{"key":"10.1016\/j.jtemb.2023.127241_bib51","doi-asserted-by":"crossref","unstructured":"J. Ye, X. Wan, Z. Zhang, Q. Chen, C. Deng, J. Zhao, Quantitative analysis of Pb with laser-induced breakdown spectroscopy in human's nail, In: Proceedings of the 2012 Symposium on Photonics and Optoelectronics, 2012, pp. 1\u20133, https:\/\/doi.org\/10.1109\/SOPO.2012.6270427.","DOI":"10.1109\/SOPO.2012.6270427"},{"key":"10.1016\/j.jtemb.2023.127241_bib52","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1364\/AO.51.002004","article-title":"Comparison between elemental composition of human fingernails of healthy and opium-addicted subjects by laser-induced breakdown spectroscopy","volume":"51","author":"Shadman","year":"2012","journal-title":"Appl. Opt."},{"key":"10.1016\/j.jtemb.2023.127241_bib53","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1007\/s00340-013-5538-7","article-title":"Elemental analysis of fingernail of alcoholic and doping subjects by laser-induced breakdown spectroscopy","volume":"114","author":"Bahreini","year":"2014","journal-title":"Appl. Phys. B"},{"key":"10.1016\/j.jtemb.2023.127241_bib54","doi-asserted-by":"crossref","first-page":"6133","DOI":"10.1364\/AO.42.006133","article-title":"Application of laser-induced breakdown spectroscopy technique to hair tissue mineral analysis","volume":"42","author":"Corsi","year":"2003","journal-title":"Appl. Opt."},{"key":"10.1016\/j.jtemb.2023.127241_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2020.105018","article-title":"Highly accurate determination of Zn and Cu in human hair by ultrasound-assisted alkali dissolution combined with laser-induced breakdown spectroscopy","volume":"157","author":"Zhang","year":"2020","journal-title":"Microchem. J."},{"key":"10.1016\/j.jtemb.2023.127241_bib56","doi-asserted-by":"crossref","first-page":"3752","DOI":"10.3390\/s21113752","article-title":"Analysis of trace metals in human hair by laser-induced breakdown spectroscopy with a compact microchip laser","volume":"21","author":"Nakagawa","year":"2021","journal-title":"Sensors"},{"key":"10.1016\/j.jtemb.2023.127241_bib57","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.talanta.2013.08.043","article-title":"Biological application of laser induced breakdown spectroscopy technique for determination of trace elements in hair","volume":"117","author":"Emara","year":"2013","journal-title":"Talanta"},{"key":"10.1016\/j.jtemb.2023.127241_bib58","first-page":"159","article-title":"The study of hair from men with androgenetic alopecia using the laser-induced breakdown spectroscopy (LIBS) technique","volume":"41","author":"Hamzaoui","year":"2018","journal-title":"Lasers Eng."},{"key":"10.1016\/j.jtemb.2023.127241_bib59","first-page":"1","article-title":"Noninvasive diagnosis of type 2 diabetes mellitus by hair analysis using laser-induced breakdown spectroscopy (LIBS","author":"Cherni","year":"2022","journal-title":"Instrum. Sci. Technol."},{"key":"10.1016\/j.jtemb.2023.127241_bib60","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1002\/9781119133780.ch22","article-title":"Biomarkers of trace element status","author":"Chojnacka","year":"2018","journal-title":"Recent Adv. Trace Elem."},{"key":"10.1016\/j.jtemb.2023.127241_bib61","doi-asserted-by":"crossref","unstructured":"T.R. Loree, The detection of elements in biomedical fluids by laser-induced breakdown spectroscopy. In: Proceedings of the International Congress on Applications of Lasers & Electro-Optics, Laser Institute of America, 1983, pp. 38\u201345.","DOI":"10.2351\/1.5057553"},{"key":"10.1016\/j.jtemb.2023.127241_bib62","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1007\/s10103-019-02866-6","article-title":"Could we diagnose childhood asthma by LIBS technique","volume":"35","author":"Alsharnoubi","year":"2020","journal-title":"Lasers Med. Sci."},{"key":"10.1016\/j.jtemb.2023.127241_bib63","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.31788\/RJC.2021.1445975","article-title":"Elemental characterization of human blood using laser-induced breakdown spectroscopy utilizing 355 nm Nd: YAG operated at reduced pressure of He gas","volume":"14","author":"Khumaeni","year":"2021","journal-title":"Rasayan J. Chem."},{"key":"10.1016\/j.jtemb.2023.127241_bib64","article-title":"Diagnosis of Alzheimer's disease using laser-induced breakdown spectroscopy and machine learning","volume":"171","author":"Gaudiuso","year":"2020","journal-title":"Spectrochim. Acta Part B Spectrosc."},{"key":"10.1016\/j.jtemb.2023.127241_bib65","doi-asserted-by":"crossref","first-page":"4191","DOI":"10.1364\/BOE.395332","article-title":"Blood cancer diagnosis using ensemble learning based on a random subspace method in laser-induced breakdown spectroscopy","volume":"11","author":"Chu","year":"2020","journal-title":"Biomed. Opt. Express"},{"key":"10.1016\/j.jtemb.2023.127241_bib66","doi-asserted-by":"crossref","first-page":"3584","DOI":"10.1364\/BOE.421333","article-title":"Diagnosis and staging of multiple myeloma using serum-based laser-induced breakdown spectroscopy combined with machine learning methods","volume":"12","author":"Chen","year":"2021","journal-title":"Biomed. Opt. Express"},{"key":"10.1016\/j.jtemb.2023.127241_bib67","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1364\/BOE.9.001057","article-title":"Discrimination of lymphoma using laser-induced breakdown spectroscopy conducted on whole blood samples","volume":"9","author":"Chen","year":"2018","journal-title":"Biomed. Opt. Express"},{"key":"10.1016\/j.jtemb.2023.127241_bib68","series-title":"Proceedings of the International Conference on Advanced Surface Enhancement","first-page":"83","article-title":"Minerals disorder determination in special cases of metastatic bone due to breast cancer using LIBS technique","author":"Emara","year":"2021"},{"key":"10.1016\/j.jtemb.2023.127241_bib69","doi-asserted-by":"crossref","first-page":"4865","DOI":"10.1364\/BOE.8.004865","article-title":"Elemental analysis of the thyroid by laser induced breakdown spectroscopy","volume":"8","author":"Ahmed","year":"2017","journal-title":"Biomed. Opt. Express"},{"key":"10.1016\/j.jtemb.2023.127241_bib70","doi-asserted-by":"crossref","first-page":"1999","DOI":"10.1364\/BOE.417738","article-title":"Primary study of identification of parathyroid gland based on laser-induced breakdown spectroscopy","volume":"12","author":"Wang","year":"2021","journal-title":"Biomed. Opt. Express"},{"key":"10.1016\/j.jtemb.2023.127241_bib71","doi-asserted-by":"crossref","first-page":"4184","DOI":"10.1364\/BOE.9.004184","article-title":"Detection of lithium in breast milk and in situ elemental analysis of the mammary gland","volume":"9","author":"Ahmed","year":"2018","journal-title":"Biomed. Opt. Express"},{"key":"10.1016\/j.jtemb.2023.127241_bib72","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.sab.2013.05.020","article-title":"Mapping nanoparticles injected into a biological tissue using laser-induced breakdown spectroscopy","volume":"87","author":"Motto-Ros","year":"2013","journal-title":"Spectrochim Acta B: At. Spectrosc."},{"key":"10.1016\/j.jtemb.2023.127241_bib73","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2020.113805","article-title":"Laser induced breakdown spectroscopy with machine learning reveals lithium-induced electrolyte imbalance in the kidneys","volume":"194","author":"Ahmed","year":"2021","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jtemb.2023.127241_bib74","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1364\/AO.54.002123","article-title":"Detection of carcinogenic metals in kidney stones using ultraviolet laser-induced breakdown spectroscopy","volume":"54","author":"Khalil","year":"2015","journal-title":"Appl. Opt."},{"key":"10.1016\/j.jtemb.2023.127241_bib75","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1007\/s10103-008-0635-2","article-title":"Cross-sectional study of kidney stones by laser-induced breakdown spectroscopy","volume":"24","author":"Singh","year":"2009","journal-title":"Lasers Med. Sci."},{"key":"10.1016\/j.jtemb.2023.127241_bib76","doi-asserted-by":"crossref","DOI":"10.1016\/j.jneumeth.2022.109676","article-title":"Visualizing the cerebral distribution of chemical elements: a challenge met with LIBS elemental imaging","volume":"379","author":"Busser","year":"2022","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.jtemb.2023.127241_bib77","doi-asserted-by":"crossref","DOI":"10.1002\/jbio.202000479","article-title":"Ex vivo three-dimensional elemental imaging of mouse brain tissue block by laser-induced breakdown spectroscopy","volume":"14","author":"Lin","year":"2021","journal-title":"J. Biophotonics"},{"key":"10.1016\/j.jtemb.2023.127241_bib78","doi-asserted-by":"crossref","first-page":"3816","DOI":"10.1364\/BOE.8.003816","article-title":"Differentiation of fibrotic liver tissue using laser-induced breakdown spectroscopy","volume":"8","author":"Teran-Hinojosa","year":"2017","journal-title":"Biomed. Opt. Express"},{"key":"10.1016\/j.jtemb.2023.127241_bib79","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.sab.2013.07.008","article-title":"Determination of the postmortem interval by laser induced breakdown spectroscopy using swine skeletal muscles. Spectrochim","volume":"88","author":"Marin-Roldan","year":"2013","journal-title":"Spectrochim. Acta B: At. Spectrosc."},{"key":"10.1016\/j.jtemb.2023.127241_bib80","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0039-9140(00)00340-4","article-title":"Zinc analysis in human skin by laser induced-breakdown spectroscopy","volume":"21","author":"Sun","year":"2000","journal-title":"Talanta"},{"key":"10.1016\/j.jtemb.2023.127241_bib81","article-title":"In-vitro analysis of early calcification in aortic valvular interstitial cells using Laser-Induced Breakdown Spectroscopy (LIBS)","volume":"11","author":"Davari","year":"2018","journal-title":"J. Biophotonics"},{"key":"10.1016\/j.jtemb.2023.127241_bib82","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/j.sab.2009.07.025","article-title":"Preliminary evaluation of laser-induced breakdown spectroscopy for tissue classification","volume":"64","author":"Yueh","year":"2009","journal-title":"Spectrochim. Acta B: At. Spectrosc."},{"key":"10.1016\/j.jtemb.2023.127241_bib83","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.sab.2013.05.012","article-title":"Pilot study of laser induced breakdown spectroscopy for tissue differentiation by monitoring the plume created during laser surgery \u2014 an approach on a feedback Laser control mechanism","volume":"87","author":"Kanawade","year":"2013","journal-title":"Spectrochim. Acta B: At. Spectrosc."},{"key":"10.1016\/j.jtemb.2023.127241_bib84","doi-asserted-by":"crossref","DOI":"10.3389\/fphy.2022.821057","article-title":"A review on laser-induced breakdown spectroscopy in different cancers diagnosis and classification","volume":"10","author":"Khan","year":"2022","journal-title":"Front. Phys."},{"key":"10.1016\/j.jtemb.2023.127241_bib85","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1364\/BOE.7.000057","article-title":"Differentiation of cutaneous melanoma from surrounding skin using laser-induced breakdown spectroscopy","volume":"7","author":"Han","year":"2016","journal-title":"Biomed. Opt. Express"},{"key":"10.1016\/j.jtemb.2023.127241_bib86","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/8826243","article-title":"Discrimination of melanoma using laser-induced breakdown spectroscopy conducted on human tissue samples","author":"Khan","year":"2020","journal-title":"J. Spectrosc."},{"key":"10.1016\/j.jtemb.2023.127241_bib87","doi-asserted-by":"crossref","DOI":"10.1016\/j.sab.2021.106090","article-title":"High spatial resolution imaging of melanoma tissue by femtosecond laser-induced breakdown spectroscopy","volume":"179","author":"Choi","year":"2021","journal-title":"Spectrochim. Acta B: At. Spectrosc."},{"key":"10.1016\/j.jtemb.2023.127241_bib88","doi-asserted-by":"crossref","first-page":"4159","DOI":"10.1364\/OE.410878","article-title":"Quantitative laser-induced breakdown spectroscopy for discriminating neoplastic tissues from non-neoplastic ones","volume":"29","author":"Al-Salihi","year":"2021","journal-title":"Opt. Express"},{"key":"10.1016\/j.jtemb.2023.127241_bib89","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.sab.2017.04.013","article-title":"Multi-elemental imaging of paraffin-embedded human samples by laser-induced breakdown spectroscopy. Spectrochim","volume":"133","author":"Moncayo","year":"2017","journal-title":"Spectrochim. Acta B: At. Spectrosc."},{"key":"10.1016\/j.jtemb.2023.127241_bib90","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1039\/D0JA00469C","article-title":"Imaging margins of skin tumors using laser-induced breakdown spectroscopy and machine learning","volume":"36","author":"Kiss","year":"2021","journal-title":"J. Anal. At. Spectrom."},{"key":"10.1016\/j.jtemb.2023.127241_bib91","doi-asserted-by":"crossref","DOI":"10.2351\/1.4989376","article-title":"Laser induced breakdown spectroscopy for the diagnosis of several malignant tissue samples","volume":"29","author":"Ghasemi","year":"2017","journal-title":"J. Laser Appl."},{"key":"10.1016\/j.jtemb.2023.127241_bib92","doi-asserted-by":"crossref","first-page":"8227","DOI":"10.1364\/AO.55.008227","article-title":"Laser induced breakdown spectroscopy and acoustic response techniques to discriminate healthy and cancerous breast tissues","volume":"55","author":"Ghasemi","year":"2016","journal-title":"Appl. Opt."},{"key":"10.1016\/j.jtemb.2023.127241_bib93","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.talanta.2010.04.064","article-title":"Exploiting LIBS as a spectrochemical analytical technique in diagnosis of some types of human malignancies","volume":"82","author":"El-Hussein","year":"2010","journal-title":"Talanta"},{"key":"10.1016\/j.jtemb.2023.127241_bib94","doi-asserted-by":"crossref","first-page":"64","DOI":"10.15171\/jlms.2019.10","article-title":"Feasibility study on discrimination of neo-plastic and non-neoplastic gastric tissues using spark discharge assisted laser induced breakdown spectroscopy","volume":"10","author":"Seifalinezhad","year":"2019","journal-title":"J. Lasers Med Sci."},{"key":"10.1016\/j.jtemb.2023.127241_bib95","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1039\/D1JA00367D","article-title":"Elemental analysis and identification of papillary thyroid cancer tissues using laser-induced breakdown spectroscopy","volume":"37","author":"Luo","year":"2022","journal-title":"J. Anal. At. Spectrom."},{"key":"10.1016\/j.jtemb.2023.127241_bib96","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1007\/s12011-020-02292-8","article-title":"Study on the molecular mechanisms against human breast cancer from insight of elemental distribution in tissue based on laser-induced breakdown spectroscopy (LIBS)","volume":"199","author":"Wei","year":"2021","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.jtemb.2023.127241_bib97","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2020.113153","article-title":"Determination of heavy metals in cancerous and healthy colon tissues using laser induced breakdown spectroscopy and its cross-validation with ICP-AES method","volume":"183","author":"Gondal","year":"2020","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jtemb.2023.127241_bib98","doi-asserted-by":"crossref","DOI":"10.1016\/j.sab.2021.106200","article-title":"Discrimination of lung tumor and boundary tissues based on laser-induced breakdown spectroscopy and machine learning","volume":"180","author":"Lin","year":"2021","journal-title":"Spectrochim. Acta B: At. Spectrosc."},{"key":"10.1016\/j.jtemb.2023.127241_bib99","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1007\/s10103-018-2500-2","article-title":"Identification of cervical cancer using laser-induced breakdown spectroscopy coupled with principal component analysis and support vector machine","volume":"33","author":"Wang","year":"2018","journal-title":"Lasers Med. Sci."},{"key":"10.1016\/j.jtemb.2023.127241_bib100","doi-asserted-by":"crossref","DOI":"10.1016\/j.sab.2020.105787","article-title":"Discrimination of infiltrative glioma boundary based on laser-induced breakdown spectroscopy","volume":"165","author":"Teng","year":"2020","journal-title":"Spectrochim. Acta B: At. Spectrosc."},{"key":"10.1016\/j.jtemb.2023.127241_bib101","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtemb.2021.126858","article-title":"Trace elements under the spotlight: a powerful nutritional tool in cancer","volume":"68","author":"Rodr\u00edguez-Tom\u00e0s","year":"2021","journal-title":"J. Trace Elem. Med. Biol."},{"key":"10.1016\/j.jtemb.2023.127241_bib102","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s00216-019-02195-1","article-title":"Calibration strategies for elemental analysis of biological samples by LA-ICP-MS and LIBS - a review","volume":"412","author":"Martinez","year":"2020","journal-title":"Anal. Bioanal. Chem."}],"container-title":["Journal of Trace Elements in Medicine and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0946672X23001177?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0946672X23001177?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T19:24:01Z","timestamp":1760556241000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0946672X23001177"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":102,"alternative-id":["S0946672X23001177"],"URL":"https:\/\/doi.org\/10.1016\/j.jtemb.2023.127241","relation":{},"ISSN":["0946-672X"],"issn-type":[{"value":"0946-672X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Medical application of laser-induced breakdown spectroscopy (LIBS) for assessment of trace element and mineral in biosamples: Laboratory and clinical validity of the method","name":"articletitle","label":"Article Title"},{"value":"Journal of Trace Elements in Medicine and Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtemb.2023.127241","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"127241"}}