{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T18:24:21Z","timestamp":1768587861650,"version":"3.49.0"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002338","name":"Ministry of Education of the People's Republic of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002338","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007166","name":"Jiangsu Province Department of Education","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004572","name":"National Health Commission of the People's Republic of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004572","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Trace Elements in Medicine and Biology"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.jtemb.2024.127550","type":"journal-article","created":{"date-parts":[[2024,10,13]],"date-time":"2024-10-13T15:36:51Z","timestamp":1728833811000},"page":"127550","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["The elemental variance between the \"rice\" and \"non-rice\" portions of Maifanitum and its health risk assessment"],"prefix":"10.1016","volume":"86","author":[{"given":"Liu","family":"Zhou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yulu","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"Fang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xilong","family":"Qian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanqiong","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiuxiu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shengjin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtemb.2024.127550_bib1","series-title":"Dictionary of traditional Chinese medicine","first-page":"1431","author":"Nanjing University of Chinese Medicine","year":"2006"},{"issue":"2","key":"10.1016\/j.jtemb.2024.127550_bib2","doi-asserted-by":"crossref","first-page":"3597","DOI":"10.4081\/ijas.2015.3597","article-title":"Effects of modified Maifanite on zearalenone toxicity in female weaner pigs","volume":"14","author":"Chen","year":"2015","journal-title":"Ital. J. Anim. Sci."},{"issue":"1","key":"10.1016\/j.jtemb.2024.127550_bib3","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1007\/s12011-012-9590-7","article-title":"Potential prevention and treatment of Maifanite for alzheimer's disease based on behavior test, oxidative stress assay, and trace element analysis in hippocampus of A\u03b2-induced AD rats","volume":"152","author":"Jiang","year":"2013","journal-title":"Biol. Trace Elem. Res."},{"issue":"6","key":"10.1016\/j.jtemb.2024.127550_bib4","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1111\/lam.13809","article-title":"Effect of maifan stone on the growth of probiotics and regulation of gut microbiota","volume":"75","author":"Li","year":"2022","journal-title":"Lett. Appl. Microbiol."},{"issue":"1","key":"10.1016\/j.jtemb.2024.127550_bib5","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s12011-013-9769-6","article-title":"Effectiveness of Maifanite in reducing the detrimental effects of cadmium on growth performance, cadmium residue, hematological parameters, serum biochemistry, and the activities of antioxidant enzymes in pigs","volume":"155","author":"Du","year":"2013","journal-title":"Biol. Trace Elem. Res."},{"issue":"1","key":"10.1016\/j.jtemb.2024.127550_bib6","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.livsci.2013.06.032","article-title":"Effectiveness of Maifanite in reducing the detrimental effects of aflatoxin B1 on hematology, aflatoxin B1 residues, and antioxidant enzymes activities of weanling piglets","volume":"157","author":"Fu","year":"2013","journal-title":"Livest. Sci."},{"issue":"13","key":"10.1016\/j.jtemb.2024.127550_bib7","doi-asserted-by":"crossref","first-page":"7683","DOI":"10.1021\/acsomega.0c00622","article-title":"Study of humic acid adsorption character on natural maifan stone: characterization, kinetics, adsorption isotherm, and thermodynamics(article)","volume":"5","author":"Yang","year":"2020","journal-title":"ACS Omega"},{"issue":"8","key":"10.1016\/j.jtemb.2024.127550_bib8","doi-asserted-by":"crossref","first-page":"4595","DOI":"10.1039\/D1RA08709F","article-title":"Study of the preparation of maifan stone and SRB immobilized particles and their effect on treatment of acid mine drainage","volume":"12","author":"Guo","year":"2022","journal-title":"RSC Adv."},{"issue":"1","key":"10.1016\/j.jtemb.2024.127550_bib9","doi-asserted-by":"crossref","first-page":"4618","DOI":"10.1038\/s41598-018-22901-w","article-title":"In situ immobilisation of toxic metals in soil using Maifan stone and illite\/smectite clay","volume":"8","author":"Ou","year":"2018","journal-title":"Sci. Rep."},{"issue":"17","key":"10.1016\/j.jtemb.2024.127550_bib10","doi-asserted-by":"crossref","first-page":"25939","DOI":"10.1007\/s11356-021-17661-6","article-title":"Effective adsorption of nutrients from simulated domestic sewage by modified Maifanite","volume":"29","author":"Liu","year":"2022","journal-title":"Environ. Sci. Pollut. Res."},{"issue":"3&4","key":"10.1016\/j.jtemb.2024.127550_bib11","first-page":"363","article-title":"Development of soil activating agents for agriculture using bakuhan-seki","volume":"5","author":"Takeda","year":"2007","journal-title":"J. Food Agric. Environ."},{"issue":"40","key":"10.1016\/j.jtemb.2024.127550_bib12","first-page":"8127","article-title":"Fuzzy cluster analysis of trace element content and therapeutic effect in traditional Chinese medicine","volume":"11","author":"Dong","year":"2007","journal-title":"J. Clin. Rehabil. Tissue Eng. Res."},{"issue":"3","key":"10.1016\/j.jtemb.2024.127550_bib13","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/0016-7037(70)90110-9","article-title":"Partition coefficients of rare-earth elements between igneous matrix material and rock-forming mineral phenocrysts-II","volume":"34","author":"Schnetzler","year":"1970","journal-title":"Geochim. Et. Cosmochim. Acta"},{"issue":"1","key":"10.1016\/j.jtemb.2024.127550_bib14","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0422-9894(08)71021-3","article-title":"Mineralogy","volume":"15","author":"Burns","year":"1977","journal-title":"Elsevier Oceanogr. Ser."},{"issue":"1) (","key":"10.1016\/j.jtemb.2024.127550_bib15","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/0079-1946(65)90014-5","article-title":"The application of trace element data to problems in petrology","volume":"6","author":"Taylor","year":"1965","journal-title":"Phys. Chem. Earth"},{"issue":"11","key":"10.1016\/j.jtemb.2024.127550_bib16","first-page":"2015","article-title":"Introduction to mineralogy and petrology","volume":"51","author":"McCallum","year":"2014","journal-title":"Choice.\u00a0Curr. Rev. Acad. Libr."},{"issue":"03","key":"10.1016\/j.jtemb.2024.127550_bib17","first-page":"608","article-title":"Geochemistry, dissolution and adsorption characteristics of Maifanitum in the northern part of Mengshan, Mengyin County, Shandong Province","volume":"59","author":"Liang","year":"2023","journal-title":"Geol. Explor."},{"issue":"02","key":"10.1016\/j.jtemb.2024.127550_bib18","first-page":"86","article-title":"Determination of major and trace elements in maifanitum by X-ray Fluorescence Spectroscopy","volume":"5","author":"Wang","year":"1989","journal-title":"J. Shenyang Archit. Civ. Eng. Inst."},{"issue":"1","key":"10.1016\/j.jtemb.2024.127550_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.21743\/pjaec\/2017.06.01","article-title":"Perilous Effects of heavy metals contamination on human health","volume":"18","author":"Zahra","year":"2017","journal-title":"Pak. J. Anal. Environ. Chem."},{"issue":"1","key":"10.1016\/j.jtemb.2024.127550_bib20","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.ecoenv.2015.01.030","article-title":"Health effects and toxicity mechanisms of rare earth elements-Knowledge gaps and research prospects","volume":"115","author":"Pagano","year":"2015","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"1","key":"10.1016\/j.jtemb.2024.127550_bib21","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/j.scitotenv.2019.02.270","article-title":"Impacts of rare earth elements on animal health and production: highlights of cerium and lanthanum","volume":"672","author":"Abdelnour","year":"2019","journal-title":"Sci. Total Environ."},{"issue":"5","key":"10.1016\/j.jtemb.2024.127550_bib22","doi-asserted-by":"crossref","first-page":"317","DOI":"10.3390\/toxics12050317","article-title":"Toxic effects of rare earth elements on human health: a review","volume":"12","author":"Wang","year":"2024","journal-title":"Toxics"},{"issue":"1","key":"10.1016\/j.jtemb.2024.127550_bib23","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.jtemb.2018.02.013","article-title":"An assessment of exposure to rare earth elements among patients receiving long-term parenteral nutrition","volume":"47","author":"Galusha","year":"2018","journal-title":"J. Trace Elem. Med. Biol."},{"issue":"1","key":"10.1016\/j.jtemb.2024.127550_bib24","article-title":"Progress in ICP-MS analysis of minerals and heavy metals in traditional medicine","volume":"13","author":"Chen","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"1","key":"10.1016\/j.jtemb.2024.127550_bib25","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.jtemb.2015.09.006","volume":"33","author":"Jin","year":"2016","journal-title":"J. Trace Elem. Med. Biol."},{"issue":"13","key":"10.1016\/j.jtemb.2024.127550_bib26","first-page":"166","article-title":"Analysis of polarizing microscopic characteristics and x-ray diffraction fingerprint of mineral medicine Maifanitum Chinese","volume":"29","author":"Wu","year":"2023","journal-title":"J. Exp. Tradit. Med. Formula"},{"issue":"5","key":"10.1016\/j.jtemb.2024.127550_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.cjac.2022.100212","article-title":"Establishment of X-ray diffraction fingerprints for identification of different configuration Realgar and its antitumor activity","volume":"51","author":"Yan","year":"2023","journal-title":"Chin., J. Anal. Chem."},{"issue":"3","key":"10.1016\/j.jtemb.2024.127550_bib28","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1177\/09731296231171443","article-title":"Simultaneous quantification of 30 elements in the mineral chinese medicine Quartz Album by ICP-MS for the identification of different geogenesis","volume":"19","author":"Xu","year":"2023","journal-title":"Pharmacogn. Mag."},{"key":"10.1016\/j.jtemb.2024.127550_bib29","series-title":"Basic Functional research on NianZishan Maifanitum in Qiqihar city Heilongiiang Province of China","author":"Wen","year":"2017"},{"key":"10.1016\/j.jtemb.2024.127550_bib30","unstructured":"National Pharmacopoeia Commission. Pharmacopoeia of the People's Republic of China (Volume Four), Beijing: China Medical Science and Technology Press (2020) 520."},{"issue":"3","key":"10.1016\/j.jtemb.2024.127550_bib31","doi-asserted-by":"crossref","first-page":"2580","DOI":"10.1007\/s11356-017-0583-0","article-title":"Health risk assessment of instant noodles commonly consumed in Port Harcourt, Nigeria","volume":"25","author":"Iniobong","year":"2018","journal-title":"Environ. Sci. Pollut. Res. Int."},{"issue":"1) (","key":"10.1016\/j.jtemb.2024.127550_bib32","article-title":"Concentration of essential and non-essential elements and carcinogenic\/non-carcinogenic health risk assessment of commercial bee pollens from Turkey","volume":"75","author":"Sevin","year":"2023","journal-title":"J. Trace Elem. Med. Biol."},{"key":"10.1016\/j.jtemb.2024.127550_bib33","unstructured":"WHO Traditional Medicine Strategy (2013) 2014-2023. \u3008https:\/\/iris.who.int\/bitstream\/handle\/10665\/92455\/9789241506090_eng.pdf?sequence=1&isAllowed=y\u3009."},{"key":"10.1016\/j.jtemb.2024.127550_bib34","unstructured":"ISO 18664 Traditional Chinese Medicine-Determination of Heavy Metals in Herbal Medicines Used in Traditional Chinese Medicine (2015): 7. \u3008https:\/\/www.iso.org\/obp\/ui\/#iso:std:iso:18664:ed-1:v1:en\u3009."},{"key":"10.1016\/j.jtemb.2024.127550_bib35","unstructured":"Japanese Pharmacopoeia 17th Edition (2016)."},{"key":"10.1016\/j.jtemb.2024.127550_bib36","unstructured":"US EPA (United Stated Environmental Protection Agency). IRIS Assessments."},{"key":"10.1016\/j.jtemb.2024.127550_bib37","series-title":"Modern Nutrition","author":"Cai","year":"2010"},{"issue":"1","key":"10.1016\/j.jtemb.2024.127550_bib38","first-page":"29","article-title":"Sodium and potassium in health and disease","volume":"13","author":"Pohl","year":"2013","journal-title":"Met. ions life Sci."},{"issue":"1","key":"10.1016\/j.jtemb.2024.127550_bib39","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/bs.afnr.2021.02.001","article-title":"The emerging role of phosphorus in human health","volume":"96","author":"Bird","year":"2021","journal-title":"Adv. Food Nutr. Res."},{"issue":"9","key":"10.1016\/j.jtemb.2024.127550_bib40","doi-asserted-by":"crossref","first-page":"8199","DOI":"10.3390\/nu7095388","article-title":"Magnesium in prevention and therapy","volume":"7","author":"Gr\u00f6ber","year":"2015","journal-title":"Nutrients"},{"issue":"5","key":"10.1016\/j.jtemb.2024.127550_bib41","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1007\/s00204-020-02702-9","article-title":"Recent aspects of the effects of zinc on human health","volume":"94","author":"Chasapis","year":"2020","journal-title":"Arch. Toxicol."},{"issue":"11","key":"10.1016\/j.jtemb.2024.127550_bib42","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.3390\/nu15112441","article-title":"Nutritional Aspects of Iron in Health and Disease","volume":"15","author":"Charlebois","year":"2023","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.jtemb.2024.127550_bib43","article-title":"The effects of manganese overexposure on brain health","volume":"135","author":"Miah","year":"2020","journal-title":"Neurochem Int"},{"issue":"11","key":"10.1016\/j.jtemb.2024.127550_bib44","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1007\/s00204-014-1355-y","article-title":"Copper: toxicological relevance and mechanisms","volume":"88","author":"Gaetke","year":"2014","journal-title":"Arch. Toxicol."},{"issue":"2","key":"10.1016\/j.jtemb.2024.127550_bib45","doi-asserted-by":"crossref","first-page":"126","DOI":"10.2174\/157340111795713807","article-title":"Role of micronutrients: boron and molybdenum in crops and in human health and nutrition","volume":"7","author":"Gupta","year":"2011","journal-title":"Curr. Nutr. Food Sci."},{"issue":"1","key":"10.1016\/j.jtemb.2024.127550_bib46","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.envint.2012.03.001","article-title":"Genotoxic effects of occupational exposure to lead and influence of polymorphisms in genes involved in lead toxicokinetics and in DNA repair","volume":"43","author":"Garc\u00eda-Lest\u00f3n","year":"2012","journal-title":"Environ. Int."},{"issue":"1","key":"10.1016\/j.jtemb.2024.127550_bib47","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.chemosphere.2016.02.060","article-title":"Presence of heavy metals in fruits and vegetables: health risk implications in Bangladesh","volume":"152","author":"Shaheen","year":"2016","journal-title":"Chemosphere"},{"issue":"2","key":"10.1016\/j.jtemb.2024.127550_bib48","doi-asserted-by":"crossref","first-page":"165","DOI":"10.3329\/jbcs.v24i2.9705","article-title":"Determination of essential and toxic metals in meats, meat products and eggs by spectrophotometric method","volume":"24","author":"Chowdhury","year":"2011","journal-title":"J. Bangladesh Chem. Soc."},{"key":"10.1016\/j.jtemb.2024.127550_bib49","doi-asserted-by":"crossref","unstructured":"R. Islam, I. Khan, S.N. Hassan, Association between type 2 diabetes and chronic arsenic exposure in drinking water: a cross sectional study in Bangladesh, Environmental health: a global access science source 11(1) (2012): 38 2012, Doi:10.1186\/1476-069X-11-38..","DOI":"10.1186\/1476-069X-11-38"},{"issue":"17","key":"10.1016\/j.jtemb.2024.127550_bib50","first-page":"81","article-title":"Methods for assessing the health risk of rare earth elements in soil to human health","volume":"42","author":"Dong","year":"2022","journal-title":"Agric. Technol."},{"issue":"1","key":"10.1016\/j.jtemb.2024.127550_bib51","first-page":"63","article-title":"Study on the biological effects of rare earth elements in the gan nan area-daily allowable intake of rare earths","volume":"17","author":"Zhu","year":"1997","journal-title":"China Environ. Sci."}],"container-title":["Journal of Trace Elements in Medicine and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0946672X24001706?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0946672X24001706?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T21:39:54Z","timestamp":1739914794000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0946672X24001706"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":51,"alternative-id":["S0946672X24001706"],"URL":"https:\/\/doi.org\/10.1016\/j.jtemb.2024.127550","relation":{},"ISSN":["0946-672X"],"issn-type":[{"value":"0946-672X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The elemental variance between the \"rice\" and \"non-rice\" portions of Maifanitum and its health risk assessment","name":"articletitle","label":"Article Title"},{"value":"Journal of Trace Elements in Medicine and Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtemb.2024.127550","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier GmbH. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"127550"}}