{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T20:07:24Z","timestamp":1788466044264,"version":"build-2803163510"},"reference-count":87,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U21A20424"],"award-info":[{"award-number":["U21A20424"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81960680"],"award-info":[{"award-number":["81960680"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82060676"],"award-info":[{"award-number":["82060676"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004775","name":"Natural Science Foundation of Gansu Province","doi-asserted-by":"publisher","award":["21ZD4FA014"],"award-info":[{"award-number":["21ZD4FA014"]}],"id":[{"id":"10.13039\/501100004775","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011192","name":"Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011192","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Trace Elements in Medicine and Biology"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.jtemb.2024.127553","type":"journal-article","created":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T05:23:05Z","timestamp":1729228985000},"page":"127553","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Nephropathy induced by cisplatin results from mitochondrial disruption, impaired energy metabolism, altered expression of renal transporters, and accumulation of urinary toxins"],"prefix":"10.1016","volume":"86","author":[{"given":"Mingkang","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianping","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanrong","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongwen","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yile","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin\u2019an","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.jtemb.2024.127553_bib1","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.kint.2020.04.020","article-title":"Controversies in acute kidney injury: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference","volume":"98","author":"Ostermann","year":"2020","journal-title":"Kidney Int"},{"issue":"6","key":"10.1016\/j.jtemb.2024.127553_bib2","doi-asserted-by":"crossref","first-page":"8421","DOI":"10.18632\/aging.202653","article-title":"PGC-1\u03b1 alleviates mitochondrial dysfunction via TFEB-mediated autophagy in cisplatin-induced acute kidney injury","volume":"13","author":"Yuan","year":"2021","journal-title":"Aging (Albany NY)"},{"issue":"Pt A) (","key":"10.1016\/j.jtemb.2024.127553_bib3","first-page":"1","article-title":"LIGHT deficiency aggravates cisplatin-induced acute kidney injury by upregulating mitochondrial apoptosis","volume":"89","author":"Yang","year":"2020","journal-title":"Int Immunopharmacol."},{"issue":"543","key":"10.1016\/j.jtemb.2024.127553_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1126\/scitranslmed.aay7591","article-title":"Nuclear receptor PXR targets AKR1B7 to protect mitochondrial metabolism and renal function in AKI","volume":"12","author":"Yu","year":"2020","journal-title":"Sci. Transl. Med."},{"issue":"1","key":"10.1016\/j.jtemb.2024.127553_bib5","doi-asserted-by":"crossref","first-page":"F145","DOI":"10.1152\/ajprenal.00164.2016","article-title":"The proximal tubule is the primary target of injury and progression of kidney disease: role of the glomerulotubular junction","volume":"311","author":"Chevalier","year":"2016","journal-title":"Am. J. Physiol. Ren. Physiol."},{"issue":"8","key":"10.1016\/j.jtemb.2024.127553_bib6","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.2215\/CJN.11290821","article-title":"Drug-induced acute kidney injury","volume":"17","author":"Perazella","year":"2022","journal-title":"Clin. J. Am. Soc. Nephrol.: CJASN"},{"issue":"8","key":"10.1016\/j.jtemb.2024.127553_bib7","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.2215\/CJN.11290821","article-title":"Drug-induced acute kidney injury","volume":"17","author":"Perazella","year":"2022","journal-title":"Clin. J. Am. Soc. Nephrol."},{"issue":"11","key":"10.1016\/j.jtemb.2024.127553_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/ijms22116109","article-title":"The mechanism of drug nephrotoxicity and the methods for preventing kidney damage","volume":"22","author":"Kwiatkowska","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"582","key":"10.1016\/j.jtemb.2024.127553_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1126\/scitranslmed.abd6299","article-title":"Mechanism and reversal of drug-induced nephrotoxicity on a chip","volume":"13","author":"Cohen","year":"2021","journal-title":"Sci. Transl. Med."},{"issue":"3","key":"10.1016\/j.jtemb.2024.127553_bib10","doi-asserted-by":"crossref","DOI":"10.1152\/ajprenal.00317.2022","article-title":"Lung cancer-kidney cross talk induces kidney injury, interstitial fibrosis, and enhances cisplatin-induced nephrotoxicity","volume":"324","author":"Orwick","year":"2023","journal-title":"Am. J. Physiol. Ren. Physiol."},{"issue":"1","key":"10.1016\/j.jtemb.2024.127553_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12951-022-01718-w","article-title":"Ameliorative impacts of polymeric and metallic nanoparticles on cisplatin-induced nephrotoxicity: a 2011-2022 review","volume":"20","author":"Davoudi","year":"2022","journal-title":"J. Nanobiotechnology"},{"issue":"8","key":"10.1016\/j.jtemb.2024.127553_bib12","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1021\/acs.chemrestox.9b00204","article-title":"Advances in toxicological research of the anticancer drug cisplatin","volume":"32","author":"Qi","year":"2019","journal-title":"Chem. Res Toxicol."},{"issue":"7","key":"10.1016\/j.jtemb.2024.127553_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/cancers13071572","article-title":"Mechanisms of cisplatin-induced acute kidney injury: pathological mechanisms, pharmacological interventions, and genetic mitigations","volume":"13","author":"McSweeney","year":"2021","journal-title":"Cancers"},{"issue":"11","key":"10.1016\/j.jtemb.2024.127553_bib14","doi-asserted-by":"crossref","first-page":"2490","DOI":"10.3390\/toxins2112490","article-title":"Mechanisms of Cisplatin nephrotoxicity","volume":"2","author":"Miller","year":"2010","journal-title":"Toxins (Basel)"},{"issue":"6","key":"10.1016\/j.jtemb.2024.127553_bib15","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1007\/s00204-014-1239-1","article-title":"Mitochondrial dysregulation and protection in cisplatin nephrotoxicity","volume":"88","author":"Yang","year":"2014","journal-title":"Arch. Toxicol."},{"issue":"2021","key":"10.1016\/j.jtemb.2024.127553_bib16","first-page":"1","article-title":"Farrerol ameliorated cisplatin-induced chronic kidney disease through mitophagy induction via Nrf2\/PINK1 Pathway","volume":"12","author":"Ma","year":"2021","journal-title":"Front Pharm."},{"issue":"3","key":"10.1016\/j.jtemb.2024.127553_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/ijms24033028","article-title":"Role of transcription factor EB in mitochondrial dysfunction of cisplatin-induced acute kidney injury","volume":"24","author":"Wang","year":"2023","journal-title":"Int J. Mol. Sci."},{"issue":"12","key":"10.1016\/j.jtemb.2024.127553_bib18","doi-asserted-by":"crossref","first-page":"2197","DOI":"10.1007\/s00204-015-1633-3","article-title":"DNA damage response in cisplatin-induced nephrotoxicity","volume":"89","author":"Zhu","year":"2015","journal-title":"Arch. Toxicol."},{"issue":"12","key":"10.1016\/j.jtemb.2024.127553_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/ijms20123011","article-title":"Recent advances in models, mechanisms, biomarkers, and interventions in cisplatin-induced acute kidney injury","volume":"20","author":"Holditch","year":"2019","journal-title":"Int. J. Mol. Sci."},{"issue":"12","key":"10.1016\/j.jtemb.2024.127553_bib20","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1038\/s41401-021-00620-9","article-title":"Natural products: potential treatments for cisplatin-induced nephrotoxicity","volume":"42","author":"Fang","year":"2021","journal-title":"Acta Pharm. Sin."},{"issue":"2021","key":"10.1016\/j.jtemb.2024.127553_bib21","first-page":"1","article-title":"The role of natural antioxidants in cisplatin-induced hepatotoxicity","volume":"144","author":"Rashid","year":"2021","journal-title":"Biomed. Pharm."},{"issue":"5","key":"10.1016\/j.jtemb.2024.127553_bib22","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.phymed.2012.12.001","article-title":"Hesperidin attenuates cisplatin-induced acute renal injury by decreasing oxidative stress, inflammation and DNA damage","volume":"20","author":"Sahu","year":"2013","journal-title":"Phytomedicine"},{"issue":"12","key":"10.1016\/j.jtemb.2024.127553_bib23","doi-asserted-by":"crossref","first-page":"3090","DOI":"10.1016\/j.fct.2011.08.018","article-title":"Carnosic acid attenuates renal injury in an experimental model of rat cisplatin-induced nephrotoxicity","volume":"49","author":"Sahu","year":"2011","journal-title":"Food Chem. Toxicol."},{"issue":"19","key":"10.1016\/j.jtemb.2024.127553_bib24","doi-asserted-by":"crossref","first-page":"21836","DOI":"10.1021\/acsami.2c00111","article-title":"Dual inhibitions on glucose\/glutamine metabolisms for nontoxic pancreatic cancer therapy","volume":"14","author":"Xu","year":"2022","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"5","key":"10.1016\/j.jtemb.2024.127553_bib25","first-page":"35","article-title":"An LC-MS\/MS analytical method for the determination of uremic toxins in patients with end-stage renal disease","volume":"191","author":"Ma","year":"2020","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"7","key":"10.1016\/j.jtemb.2024.127553_bib26","doi-asserted-by":"crossref","first-page":"4205","DOI":"10.1039\/D2FO00298A","article-title":"Hesperidin protects against cisplatin-induced cardiotoxicity in mice by regulating the p62-Keap1-Nrf2 pathway","volume":"13","author":"Jia","year":"2022","journal-title":"Food Funct."},{"key":"10.1016\/j.jtemb.2024.127553_bib27","first-page":"1","article-title":"Mitophagy impairment aggravates cisplatin-induced ototoxicity","author":"Cho","year":"2021","journal-title":"Biomed. Res Int"},{"issue":"3","key":"10.1016\/j.jtemb.2024.127553_bib28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/ijms23031532","article-title":"Pharmacological effects of cisplatin combination with natural products in cancer chemotherapy","volume":"23","author":"Dasari","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"9","key":"10.1016\/j.jtemb.2024.127553_bib29","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1111\/boc.202100002","article-title":"Mitochondrial protein import as a quality control sensor","volume":"113","author":"Maity","year":"2021","journal-title":"Biol. Cell"},{"issue":"2","key":"10.1016\/j.jtemb.2024.127553_bib30","doi-asserted-by":"crossref","first-page":"143","DOI":"10.2174\/1570159X13666150703154541","article-title":"Mitochondrial biology and neurological diseases","volume":"14","author":"Arun","year":"2016","journal-title":"Curr. Neuropharmacol."},{"issue":"2","key":"10.1016\/j.jtemb.2024.127553_bib31","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1080\/15548627.2022.2084862","article-title":"Mitochondria ROS and mitophagy in acute kidney injury","volume":"19","author":"Su","year":"2023","journal-title":"Autophagy"},{"issue":"5","key":"10.1016\/j.jtemb.2024.127553_bib32","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.kint.2023.01.025","article-title":"Cobaltosic oxide-polyethylene glycol-triphenylphosphine nanoparticles ameliorate the acute-to-chronic kidney disease transition by inducing BNIP3-mediated mitophagy","volume":"103","author":"Qin","year":"2023","journal-title":"Kidney Int."},{"issue":"3","key":"10.1016\/j.jtemb.2024.127553_bib33","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1093\/toxres\/tfac019","article-title":"Mechanism of kidney injury induced by cisplatin","volume":"11","author":"Huang","year":"2022","journal-title":"Toxicol. Res"},{"issue":"3","key":"10.1016\/j.jtemb.2024.127553_bib34","first-page":"1","article-title":"Autophagy and necroptosis in cisplatin-induced acute kidney injury: Recent advances regarding their role and therapeutic potential","volume":"14","author":"Noha","year":"2023","journal-title":"Front. Pharmacol."},{"issue":"10","key":"10.1016\/j.jtemb.2024.127553_bib35","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/j.tcb.2022.03.012","article-title":"The multifaceted role of kidney tubule mitochondrial dysfunction in kidney disease development","volume":"32","author":"Doke","year":"2022","journal-title":"Trends Cell Biol."},{"issue":"5","key":"10.1016\/j.jtemb.2024.127553_bib36","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1038\/s41581-020-00369-0","article-title":"Mitochondrial quality control in kidney injury and repair","volume":"17","author":"Tang","year":"2020","journal-title":"Nat. Rev. Nephrol."},{"issue":"7","key":"10.1016\/j.jtemb.2024.127553_bib37","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1681\/ASN.2018111126","article-title":"Mitochondria in Sepsis-Induced AKI","volume":"30","author":"Sun","year":"2019","journal-title":"J. Am. Soc. Nephrol."},{"issue":"2023","key":"10.1016\/j.jtemb.2024.127553_bib38","first-page":"1","article-title":"Metabolomics for the identification of early biomarkers of nephrotoxicity in a mouse model of cisplatin-induced acute kidney injury","volume":"163","author":"Lim","year":"2023","journal-title":"Biomed. Pharm."},{"issue":"8","key":"10.1016\/j.jtemb.2024.127553_bib39","doi-asserted-by":"crossref","first-page":"12537","DOI":"10.1002\/jcp.28122","article-title":"Mechanisms of apoptosis modulation by curcumin: Implications for cancer therapy","volume":"234","author":"Mortezaee","year":"2019","journal-title":"J. Cell. Physiol."},{"issue":"5","key":"10.1016\/j.jtemb.2024.127553_bib40","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1023\/A:1009616228304","article-title":"Haj-Yehia, Levi-Schaffer, Role of reactive oxygen species (ROS) in apoptosis induction","volume":"5","author":"Simon","year":"2000","journal-title":"Apoptosis"},{"issue":"10","key":"10.1016\/j.jtemb.2024.127553_bib41","doi-asserted-by":"crossref","first-page":"3945","DOI":"10.1111\/cas.15068","article-title":"Reactive oxygen species in cancer: current findings and future directions","volume":"112","author":"Nakamura","year":"2021","journal-title":"Cancer Sci."},{"issue":"2","key":"10.1016\/j.jtemb.2024.127553_bib42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/biology12020327","article-title":"Renal microcirculation injury as the main cause of ischemic acute kidney injury development","volume":"12","author":"Kwiatkowska","year":"2023","journal-title":"Biology"},{"issue":"2","key":"10.1016\/j.jtemb.2024.127553_bib43","doi-asserted-by":"crossref","first-page":"F264","DOI":"10.1152\/ajprenal.00045.2019","article-title":"Renal tubular injury exacerbated by Vasohibin-1 deficiency in a murine cisplatin-induced acute kidney injury model","volume":"17","author":"Tanimura","year":"2019","journal-title":"Am. J. Physiol. Ren. Physiol."},{"issue":"3-4","key":"10.1016\/j.jtemb.2024.127553_bib44","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1080\/10520290802451085","article-title":"Immunohistochemistry in the evaluation of neovascularization in tumor xenografts","volume":"83","author":"Wang","year":"2008","journal-title":"Biotech. Histochem"},{"issue":"4","key":"10.1016\/j.jtemb.2024.127553_bib45","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1038\/clpt.2009.139","article-title":"Contribution of organic cation transporter 2 (OCT2) to cisplatin-induced nephrotoxicity","volume":"86","author":"Filipski","year":"2009","journal-title":"Clin. Pharmacol. Ther."},{"issue":"1","key":"10.1016\/j.jtemb.2024.127553_bib46","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1007\/s12011-014-9914-x","article-title":"Effect of lycopene against cisplatin-induced acute renal injury in rats: organic anion and cation transporters evaluation","volume":"158","author":"Erman","year":"2014","journal-title":"Biol. Trace Elem. Res."},{"issue":"14) (","key":"10.1016\/j.jtemb.2024.127553_bib47","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.freeradbiomed.2021.08.008","article-title":"Transcriptomic analysis of rat kidney reveals a potential mechanism of sex differences in susceptibility to cisplatin-induced nephrotoxicity","volume":"174","author":"Hwang","year":"2021","journal-title":"Free Radic. Biol. Med."},{"issue":"2020","key":"10.1016\/j.jtemb.2024.127553_bib48","first-page":"1","article-title":"An LC-MS\/MS analytical method for the determination of uremic toxins in patients with end-stage renal disease","volume":"191","author":"Ma","year":"2020","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"20","key":"10.1016\/j.jtemb.2024.127553_bib49","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.trsl.2020.09.001","article-title":"Challenges of reducing protein-bound uremic toxin levels in chronic kidney disease and end stage renal disease","volume":"229","author":"Faria","year":"2021","journal-title":"Transl. Res."},{"issue":"7","key":"10.1016\/j.jtemb.2024.127553_bib50","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1681\/ASN.2011121175","article-title":"Normal and pathologic concentrations of uremic toxins","volume":"23","author":"Duranton","year":"2012","journal-title":"J. Am. Soc. Nephrol."},{"issue":"19","key":"10.1016\/j.jtemb.2024.127553_bib51","doi-asserted-by":"crossref","DOI":"10.15252\/embj.2021108863","article-title":"Autophagy in major human diseases","volume":"40","author":"Klionsky","year":"2021","journal-title":"EMBO J."},{"issue":"13","key":"10.1016\/j.jtemb.2024.127553_bib52","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/ijms23137241","article-title":"Can cisplatin therapy be improved? Pathways that can be targeted","volume":"23","author":"Ali","year":"2022","journal-title":"Int J. Mol. Sci."},{"issue":"3","key":"10.1016\/j.jtemb.2024.127553_bib53","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.toxlet.2015.06.012","article-title":"An integrated view of cisplatin-induced nephrotoxicity and ototoxicity","volume":"237","author":"Karasawa","year":"2015","journal-title":"Toxicol. Lett."},{"issue":"9","key":"10.1016\/j.jtemb.2024.127553_bib54","doi-asserted-by":"crossref","first-page":"4839","DOI":"10.1039\/D1FO04391A","article-title":"Protective effect of food derived nutrients on cisplatin nephrotoxicity and its mechanism","volume":"13","author":"Liu","year":"2022","journal-title":"Food Funct."},{"issue":"2017","key":"10.1016\/j.jtemb.2024.127553_bib55","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.fct.2017.07.018","article-title":"Curcumin prevents cisplatin-induced renal alterations in mitochondrial bioenergetics and dynamic","volume":"107","author":"Ortega-Dom\u00ednguez","year":"2017","journal-title":"Food Chem. Toxicol."},{"issue":"14","key":"10.1016\/j.jtemb.2024.127553_bib56","article-title":"Honokiol ameliorates cisplatin-induced acute kidney injury via inhibition of mitochondrial fission","volume":"179","author":"Rui-Wen","year":"2022","journal-title":"Br. J. Pharmacol."},{"issue":"13","key":"10.1016\/j.jtemb.2024.127553_bib57","article-title":"Activation of TFEB-mediated autophagy by trehalose attenuates mitochondrial dysfunction in cisplatin-induced acute kidney injury","volume":"10","author":"Lingling","year":"2020","journal-title":"Theranostics"},{"issue":"0) (","key":"10.1016\/j.jtemb.2024.127553_bib58","article-title":"The copper transporter, SLC31A1, transcriptionally activated by ELF3, imbalances copper homeostasis to exacerbate cisplatin-induced acute kidney injury through mitochondrial dysfunction","volume":"393","author":"Zhimin","year":"2024","journal-title":"Chem. Biol. Inter."},{"issue":"11","key":"10.1016\/j.jtemb.2024.127553_bib59","article-title":"Inhibition of TMEM16A improves cisplatin-induced acute kidney injury via preventing DRP1-mediated mitochondrial fission","volume":"44","author":"Xiao-Long","year":"2023","journal-title":"Acta Pharm. Sin."},{"issue":"21","key":"10.1016\/j.jtemb.2024.127553_bib60","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/ijms232113093","article-title":"Magnesium Isoglycyrrhizinate reduces the target-binding amount of Cisplatin to Mitochondrial DNA and renal injury through SIRT3","volume":"23","author":"Wang","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"10","key":"10.1016\/j.jtemb.2024.127553_bib61","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1038\/nrneph.2017.107","article-title":"Mitochondrial energetics in the kidney","volume":"13","author":"Bhargava","year":"2017","journal-title":"Nat. Rev. Nephrol."},{"issue":"0) (","key":"10.1016\/j.jtemb.2024.127553_bib62","article-title":"Maintaining homeostasis of mitochondria and endoplasmic reticulum with NSC228155 alleviates cisplatin-induced acute kidney injury","volume":"181","author":"Yanwei","year":"2022","journal-title":"Free Radic. Biol. Med"},{"issue":"9","key":"10.1016\/j.jtemb.2024.127553_bib63","article-title":"Sirt3 modulates fatty acid oxidation and attenuates cisplatin-induced AKI in mice","volume":"24","author":"Ming","year":"2020","journal-title":"J. Cell Mol. Med"},{"issue":"0","key":"10.1016\/j.jtemb.2024.127553_bib64","article-title":"Isorhamnetin alleviates cisplatin-induced acute kidney injury via enhancing fatty acid oxidation","volume":"212","author":"Lingkun","year":"2023","journal-title":"Free Radic. Biol. Med."},{"issue":"0) (","key":"10.1016\/j.jtemb.2024.127553_bib65","article-title":"Celastrol ameliorates cisplatin nephrotoxicity by inhibiting NF-\u03baB and improving mitochondrial function","volume":"36","author":"Xiaowen","year":"2018","journal-title":"EBioMedicine"},{"key":"10.1016\/j.jtemb.2024.127553_bib66","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.2147\/IJN.S444076","article-title":"Artesunate-Nanoliposome-TPP, a novel drug delivery system that targets the mitochondria, attenuates cisplatin-induced acute kidney injury by suppressing oxidative stress and inflammatory effects","volume":"19","author":"Zhang","year":"2024","journal-title":"Int. J. Nanomed."},{"issue":"1","key":"10.1016\/j.jtemb.2024.127553_bib67","doi-asserted-by":"crossref","DOI":"10.1038\/s41420-024-01872-0","article-title":"The interplay of mitophagy, autophagy, and apoptosis in cisplatin-induced kidney injury: involvement of ERK signaling pathway","volume":"10","author":"Suman","year":"2024","journal-title":"Cell Death Discov."},{"issue":"8","key":"10.1016\/j.jtemb.2024.127553_bib68","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0135083","article-title":"Mechanism of cisplatin-induced cytotoxicity is correlated to impaired metabolism due to mitochondrial ROS generation","volume":"10","author":"Choi","year":"2015","journal-title":"PloS One"},{"issue":"7","key":"10.1016\/j.jtemb.2024.127553_bib69","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1089\/ars.2020.8058","article-title":"Mitochondrial reactive oxygen species and mitophagy: a complex and nuanced relationship","volume":"34","author":"Schofield","year":"2021","journal-title":"Antioxid. Redox Signal."},{"issue":"24","key":"10.1016\/j.jtemb.2024.127553_bib70","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/ijms232416053","article-title":"Mitochondrial dysfunction and therapeutic perspectives in cardiovascular diseases","volume":"23","author":"Liu","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"2019","key":"10.1016\/j.jtemb.2024.127553_bib71","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.redox.2018.09.020","article-title":"Persistent increase in mitochondrial superoxide mediates cisplatin-induced chronic kidney disease","volume":"20","author":"Mapuskar","year":"2019","journal-title":"Redox Biol."},{"issue":"3","key":"10.1016\/j.jtemb.2024.127553_bib72","article-title":"Role of transcription factor EB in mitochondrial dysfunction of cisplatin-induced acute kidney injury","volume":"24","author":"Shujun","year":"2023","journal-title":"Int J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.jtemb.2024.127553_bib73","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1002\/2211-5463.12760","article-title":"Panax notoginseng saponins ameliorate cisplatin-induced mitochondrial injury via the HIF-1\u03b1\/mitochondria\/ROS pathway","volume":"10","author":"Li","year":"2020","journal-title":"FEBS Open bio"},{"issue":"5","key":"10.1016\/j.jtemb.2024.127553_bib74","doi-asserted-by":"crossref","first-page":"H2023","DOI":"10.1152\/ajpheart.01283.2006","article-title":"Mitochondrial reactive oxygen species-mediated signaling in endothelial cells","volume":"292","author":"Zhang","year":"2007","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"4","key":"10.1016\/j.jtemb.2024.127553_bib75","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/apha.13477","article-title":"Reactive oxygen species in renal vascular function","volume":"229","author":"Xu","year":"2020","journal-title":"Acta Physiol."},{"issue":"2) (","key":"10.1016\/j.jtemb.2024.127553_bib76","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.niox.2018.05.003","article-title":"N-acetylcysteine protects against diabetic nephropathy through control of oxidative and nitrosative stress by recovery of nitric oxide in rats","volume":"78","author":"Nogueira","year":"2018","journal-title":"Nitric Oxide"},{"issue":"6","key":"10.1016\/j.jtemb.2024.127553_bib77","doi-asserted-by":"crossref","first-page":"4347","DOI":"10.1021\/acsomega.0c05586","article-title":"(\u2212)-Epigallocatechin-3-gallate inhibits human and rat renal organic anion transporters","volume":"6","author":"Kawasaki","year":"2021","journal-title":"ACS Omega"},{"issue":"5","key":"10.1016\/j.jtemb.2024.127553_bib78","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1016\/j.fct.2012.02.082","article-title":"Regulation of renal organic anion and cation transporters by thymoquinone in cisplatin induced kidney injury","volume":"50","author":"Ulu","year":"2012","journal-title":"Food Chem. Toxicol."},{"issue":"2-3","key":"10.1016\/j.jtemb.2024.127553_bib79","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.tox.2008.06.009","article-title":"Renal xenobiotic transporters are differentially expressed in mice following cisplatin treatment","volume":"250","author":"Aleksunes","year":"2008","journal-title":"Toxicology"},{"issue":"11","key":"10.1016\/j.jtemb.2024.127553_bib80","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/toxins12110684","article-title":"Indoxyl sulfate, a tubular toxin, contributes to the development of chronic kidney disease","volume":"12","author":"Cheng","year":"2020","journal-title":"Toxins"},{"issue":"14","key":"10.1016\/j.jtemb.2024.127553_bib81","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1042\/CS20160191","article-title":"Disposition and clinical implications of protein-bound uremic toxins","volume":"131","author":"Jansen","year":"2017","journal-title":"Clin. Sci."},{"issue":"4","key":"10.1016\/j.jtemb.2024.127553_bib82","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1007\/s11095-005-2486-x","article-title":"Differential contributions of rOat1 (Slc22a6) and rOat3 (Slc22a8) to the in vivo renal uptake of uremic toxins in rats","volume":"22","author":"Deguchi","year":"2005","journal-title":"Pharm. Res."},{"issue":"1","key":"10.1016\/j.jtemb.2024.127553_bib83","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-021-86662-9","article-title":"Hypouricemic agents reduce indoxyl sulfate excretion by inhibiting the renal transporters OAT1\/3 and ABCG2","volume":"11","author":"Taniguchi","year":"2021","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.jtemb.2024.127553_bib84","first-page":"1","article-title":"Transport of kynurenic acid by rat organic anion transporters rOAT1 and rOAT3: species difference between human and Rat in OAT1","volume":"6","author":"Uwai","year":"2013","journal-title":"Int. J. tryptophan Res.: IJTR"},{"issue":"6","key":"10.1016\/j.jtemb.2024.127553_bib85","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1124\/dmd.116.074492","article-title":"Increased plasma exposures of conjugated metabolites of morinidazole in renal failure patients: a critical role of uremic toxins","volume":"45","author":"Kong","year":"2017","journal-title":"Drug Metab. Dispos."},{"issue":"4","key":"10.1016\/j.jtemb.2024.127553_bib86","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.7150\/ijbs.80775","article-title":"Mitophagy alleviates cisplatin-induced renal tubular epithelial cell ferroptosis through ROS\/HO-1\/GPX4 axis","volume":"19","author":"Lin","year":"2023","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.jtemb.2024.127553_bib87","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.918732","article-title":"Persistent activation of autophagy after cisplatin nephrotoxicity promotes renal fibrosis and chronic kidney disease","volume":"13","author":"Fu","year":"2022","journal-title":"Front. Pharmacol."}],"container-title":["Journal of Trace Elements in Medicine and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0946672X24001731?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0946672X24001731?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T16:10:08Z","timestamp":1778515808000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0946672X24001731"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":87,"alternative-id":["S0946672X24001731"],"URL":"https:\/\/doi.org\/10.1016\/j.jtemb.2024.127553","relation":{},"ISSN":["0946-672X"],"issn-type":[{"value":"0946-672X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nephropathy induced by cisplatin results from mitochondrial disruption, impaired energy metabolism, altered expression of renal transporters, and accumulation of urinary toxins","name":"articletitle","label":"Article Title"},{"value":"Journal of Trace Elements in Medicine and Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtemb.2024.127553","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier GmbH. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"127553"}}