{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T19:46:00Z","timestamp":1769629560389,"version":"3.49.0"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T00:00:00Z","timestamp":1767744000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Trace Elements in Medicine and Biology"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.jtemb.2026.127816","type":"journal-article","created":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T08:10:26Z","timestamp":1767773426000},"page":"127816","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Association of iodine nutritional status with thyroid nodules and papillary thyroid carcinoma in women from an iodine-sufficient region in Brazil: A cross-sectional center study"],"prefix":"10.1016","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-1058-6740","authenticated-orcid":false,"given":"Ivia","family":"Fonseca","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aline Larcher de","family":"Almeida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patr\u00edcia Borges dos","family":"Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalia","family":"Treistman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tales","family":"Aprigio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Vaisman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Paula Aguiar","family":"Vidal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patr\u00edcia de F\u00e1tima dos Santos","family":"Teixeira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathalie Silva de","family":"Morais","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jtemb.2026.127816_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/thy.2015.0020","article-title":"2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer","volume":"26","author":"Haugen","year":"2016","journal-title":"Thyroid"},{"issue":"7","key":"10.1016\/j.jtemb.2026.127816_bib2","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/S2213-8587(22)00101-2","article-title":"Diagnosis of thyroid nodules","volume":"10","author":"Alexander","year":"2022","journal-title":"Lancet Diabetes Endocrinol."},{"key":"10.1016\/j.jtemb.2026.127816_bib3","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.nutres.2019.02.009","article-title":"Excessive iodine intake is associated with formation of thyroid nodules in pregnant Chinese women","volume":"66","author":"Gao","year":"2019","journal-title":"Nutr. Res"},{"key":"10.1016\/j.jtemb.2026.127816_bib4","article-title":"The effect of iodine status on the risk of thyroid nodules: a cross-sectional study in Zhejiang, China","volume":"2020","author":"Lou","year":"2020","journal-title":"Int J. Endocrinol. 18"},{"issue":"3","key":"10.1016\/j.jtemb.2026.127816_bib5","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1007\/s00394-015-1144-2","article-title":"Strong association of relatively low and extremely excessive iodine intakes with thyroid cancer in an iodine-replete area","volume":"56","author":"Kim","year":"2017","journal-title":"Eur. J. Nutr."},{"issue":"10","key":"10.1016\/j.jtemb.2026.127816_bib6","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1210\/en.2019-00315","article-title":"Impact of BRAF V600E and TERT promoter mutations on response to therapy in papillary thyroid cancer","volume":"160","author":"Trybek","year":"2019","journal-title":"Endocrinology"},{"issue":"2","key":"10.1016\/j.jtemb.2026.127816_bib7","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/s12020-019-01901-4","article-title":"Relationship between metabolic syndrome and thyroid nodules and thyroid volume in an adult population","volume":"65","author":"Guo","year":"2019","journal-title":"Endocrine"},{"key":"10.1016\/j.jtemb.2026.127816_bib8","unstructured":"Eastman C.J., Zimmermann M.B. (2018). The Iodine Deficiency Disorders. In: Endotext [Internet]. South Dartmouth (MA): MDText.com."},{"issue":"9","key":"10.1016\/j.jtemb.2026.127816_bib9","article-title":"Iodine nutrition and papillary thyroid cancer","volume":"20","author":"Zhang","year":"2022","journal-title":"Front Nutr."},{"key":"10.1016\/j.jtemb.2026.127816_bib10","first-page":"bnae019","article-title":"Risks of iodine excess","volume":"13","author":"Sohn","year":"2024","journal-title":"Endocr. Rev."},{"issue":"12","key":"10.1016\/j.jtemb.2026.127816_bib11","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1530\/EC-21-0418","article-title":"Iodine nutritional status, the prevalence of thyroid goiter and nodules in rural and urban residents: a cross-sectional study from Guangzhou, China","volume":"10","author":"Yan","year":"2021","journal-title":"Endocr. Connect"},{"issue":"17","key":"10.1016\/j.jtemb.2026.127816_bib12","doi-asserted-by":"crossref","first-page":"3474","DOI":"10.3390\/nu14173474","article-title":"Iodine and iodine deficiency: a comprehensive review of a re-emerging issue","volume":"14","author":"Hatch-McChesney","year":"2022","journal-title":"Nutrients"},{"issue":"12","key":"10.1016\/j.jtemb.2026.127816_bib13","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1038\/nrendo.2014.187","article-title":"Thyroid gland: iodine deficiency and thyroid nodules","volume":"10","author":"Zimmermann","year":"2014","journal-title":"Nat. Rev. Endocrinol."},{"issue":"4","key":"10.1016\/j.jtemb.2026.127816_bib14","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1210\/er.2009-0011","article-title":"Iodine deficiency","volume":"30","author":"Zimmermann","year":"2009","journal-title":"Endocr. Rev."},{"issue":"4","key":"10.1016\/j.jtemb.2026.127816_bib15","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1089\/met.2018.0094","article-title":"Association between thyroid nodules and volume and metabolic syndrome in an iodine-adequate area: a large community-based population study","volume":"17","author":"Su","year":"2019","journal-title":"Metab. Syndr. Relat. Disord."},{"issue":"4","key":"10.1016\/j.jtemb.2026.127816_bib16","doi-asserted-by":"crossref","first-page":"790","DOI":"10.3803\/EnM.2021.1034","article-title":"Association between iodine intake, thyroid function, and papillary thyroid cancer: a case-control study","volume":"36","author":"Kim","year":"2021","journal-title":"Endocrinol. Metab. (Seoul. )"},{"issue":"5","key":"10.1016\/j.jtemb.2026.127816_bib17","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.21037\/gs-20-346","article-title":"Changing patterns of thyroid cancer in different stages of Universal Salt Iodization in Peking Union Medical College Hospital, 1986-2018","volume":"9","author":"Zeng","year":"2020","journal-title":"Gland Surg."},{"key":"10.1016\/j.jtemb.2026.127816_bib18","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.canep.2016.07.002","article-title":"Iodine deficiency and thyroid cancer trends in three regions of Thailand, 1990-2009","volume":"43","author":"Mitro","year":"2016","journal-title":"Cancer Epidemiol."},{"issue":"1","key":"10.1016\/j.jtemb.2026.127816_bib19","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1038\/s41598-023-29071-4","article-title":"Association between urinary iodine concentration and the risk of papillary thyroid cancer by sex and age: a case-control study","volume":"13","author":"Hwang","year":"2023","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.jtemb.2026.127816_bib20","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1159\/000481844","article-title":"Iodine promotes tumorigenesis of thyroid cancer by suppressing Mir-422a and up-regulating MAPK1","volume":"43","author":"Wang","year":"2017","journal-title":"Cell Physiol. Biochem"},{"key":"10.1016\/j.jtemb.2026.127816_bib21","doi-asserted-by":"crossref","first-page":"2288","DOI":"10.12659\/MSM.893486","article-title":"Effect of iodine intake on p14ARF and p16INK4a expression in thyroid papillary carcinoma in rats","volume":"21","author":"Sun","year":"2015","journal-title":"Med Sci. Monit."},{"issue":"4","key":"10.1016\/j.jtemb.2026.127816_bib22","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1089\/thy.2015.0352","article-title":"Increase in papillary thyroid cancer incidence is accompanied by changes in the frequency of the BRAF V600E mutation: a single-institution study","author":"Kowalska","year":"2016","journal-title":"Thyroid"},{"issue":"2","key":"10.1016\/j.jtemb.2026.127816_bib23","doi-asserted-by":"crossref","first-page":"E276","DOI":"10.1210\/jc.2013-2503","article-title":"The increase in thyroid cancer incidence during the last four decades is accompanied by a high frequency of BRAF mutations and a sharp increase in RAS mutations","volume":"99","author":"Jung","year":"2014","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"5","key":"10.1016\/j.jtemb.2026.127816_bib24","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1210\/jc.2008-2390","article-title":"Association of high iodine intake with the T1799A BRAF mutation in papillary thyroid cancer","volume":"94","author":"Guan","year":"2009","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.jtemb.2026.127816_bib25","doi-asserted-by":"crossref","DOI":"10.20945\/2359-3997000000530","article-title":"Iodine nutritional status is not a direct factor in the prevalence of the BRAFV600E mutation in papillary thyroid cancer","author":"Lin","year":"2023","journal-title":"Arch. Endocrinol. Metab. 67(2)172178"},{"key":"10.1016\/j.jtemb.2026.127816_bib26","unstructured":"Ministry of Health (Brazil) (2008). Secretariat of Health Care. Technical and Operational Manual of Pro-Iodine: National Program for the Prevention and Control of Iodine Deficiency Disorders \u3008https:\/\/bvsms.saude.gov.br\/bvs\/publicacoes\/manual_tecnico_operacional_proiodo.pdf\u3009 Accessed 30 September 2024."},{"key":"10.1016\/j.jtemb.2026.127816_bib27","unstructured":"Ministry of Health (Brazil) (2022). Resolution of the Collegiate Board No. 604. Provides for the iodine content in salt intended for human consumption and other measures. Official Gazette of the Union. \u3008https:\/\/antigo.anvisa.gov.br\/documents\/10181\/6394607\/RDC_604_2022_.pdf\/e60cf59a-ecec-4921-832f-37cef89268da#:\u223c:text=Disp%C3%B5e%20sobre%20o%20enriquecimento%20obrigat%C3%B3rio,f%C3%B3lico%20destinados%20ao%20consumo%20humano\u3009. Accessed 30 September 2024."},{"key":"10.1016\/j.jtemb.2026.127816_bib28","unstructured":"Iodine Global Network (2021). Annual Report 2021. \u3008https:\/\/ign.org\/app\/uploads\/2023\/05\/11560-IGN-Annual-Report-2021.pdf\u3009. Accessed 16 May 2023."},{"key":"10.1016\/j.jtemb.2026.127816_bib29","unstructured":"Santos, I.S.; Cesar, J.A. (2016). National Survey to Assess the Impact of Salt Iodization (PNAISAL). \u3008http:\/\/189.28.128.100\/dab\/docs\/portaldab\/documentos\/pnaisal_relatorio_final.pdf\u3009. Accessed 14 January 2023."},{"key":"10.1016\/j.jtemb.2026.127816_bib30","unstructured":"National Cancer Institute (Brazil) (2022). Estimate 2023: cancer incidence in Brazil \/ National Cancer Institute. \u3008https:\/\/www.inca.gov.br\/sites\/ufu.sti.inca.local\/files\/\/media\/document\/\/estimativa-2023.pdf\u3009 Accessed 29 September 2024."},{"issue":"12","key":"10.1016\/j.jtemb.2026.127816_bib31","article-title":"Mapping global epidemiology of thyroid nodules among general population: a systematic review and meta-analysis","volume":"10","author":"Mu","year":"2022","journal-title":"Front Oncol."},{"issue":"5","key":"10.1016\/j.jtemb.2026.127816_bib32","doi-asserted-by":"crossref","first-page":"T273","DOI":"10.1530\/ERC-14-0053","article-title":"Estrogen and its role in thyroid cancer","volume":"21","author":"Derwahl","year":"2014","journal-title":"Endocr. Relat. Cancer"},{"key":"10.1016\/j.jtemb.2026.127816_bib33","doi-asserted-by":"crossref","first-page":"465","DOI":"10.3389\/fendo.2019.00465","article-title":"Effects of metformin on TSH levels and benign nodular goiter volume in patients without insulin resistance or iodine insufficiency","volume":"10","author":"Dos Santos","year":"2019","journal-title":"Front Endocrinol. (Lausanne)"},{"key":"10.1016\/j.jtemb.2026.127816_bib34","unstructured":"WHO, UNICEF, ICCIDD 2007 Assessment of the Iodine Deficiency Disorders and Monitoring their Elimination. Third edition. Geneva: World Health Organization, WHO\/NHD."},{"issue":"4-5","key":"10.1016\/j.jtemb.2026.127816_bib35","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.autrev.2014.01.007","article-title":"Hashimoto thyroiditis: clinical and diagnostic criteria","volume":"13","author":"Caturegli","year":"2014","journal-title":"Autoimmun. Rev."},{"issue":"1","key":"10.1016\/j.jtemb.2026.127816_bib36","doi-asserted-by":"crossref","first-page":"234","DOI":"10.2214\/AJR.04.0816","article-title":"Measuring thyroid gland volume: should we change the correction factor?","volume":"186","author":"Shabana","year":"2006","journal-title":"AJR Am. J. Roentgenol."},{"issue":"9","key":"10.1016\/j.jtemb.2026.127816_bib37","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1002\/dc.23516","article-title":"Ultrasonographic and cytopathological features of an inflammatory pseudonodule in the thyroid gland","volume":"44","author":"Jung","year":"2016","journal-title":"Diagn. Cytopathol."},{"key":"10.1016\/j.jtemb.2026.127816_bib38","doi-asserted-by":"crossref","DOI":"10.1089\/thy.2023.0141","article-title":"The 2023 bethesda system for reporting thyroid cytopathology","author":"Ali","year":"2023","journal-title":"Thyroid"},{"key":"10.1016\/j.jtemb.2026.127816_bib39","unstructured":"WHO Classification of Tumours Editorial Board (2022). Endocrine and neuroendocrine tumours. Lyon: International Agency for Research on Cancer. \u3008https:\/\/tumourclassification.iarc.who.int\/chapters\/36\u3009."},{"key":"10.1016\/j.jtemb.2026.127816_bib40","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s12022-022-09707-3","article-title":"Overview of the WHO classification of thyroid neoplasms","volume":"33","author":"Baloch","year":"2022","journal-title":"Endocr. Pathol."},{"key":"10.1016\/j.jtemb.2026.127816_bib41","first-page":"83","article-title":"BRAFV600E immunohistochemistry in papillary thyroid carcinomas: relationship between clinical and morphological parameters","volume":"35","author":"Kombak","year":"2019","journal-title":"Turk. Patoloji Derg."},{"key":"10.1016\/j.jtemb.2026.127816_bib42","first-page":"15072","article-title":"Immunohistochemistry is highly sensitive and specific for detecting the BRAF V600E mutation in papillary thyroid carcinoma","volume":"8","author":"Sun","year":"2015","journal-title":"Int J. Clin. Exp. Pathol."},{"issue":"n3","key":"10.1016\/j.jtemb.2026.127816_bib43","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1080\/00401706.1964.10490181","article-title":"Multiple Comparisons using rank sums","volume":"v6","author":"Dunn","year":"1964","journal-title":"Technomethrics"},{"issue":"5","key":"10.1016\/j.jtemb.2026.127816_bib44","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1097\/MED.0000000000000570","article-title":"Hashimoto's thyroiditis as a risk factor for thyroid cancer","volume":"27","author":"Feldt-Rasmussen","year":"2020","journal-title":"Curr. Opin. Endocrinol. Diabetes Obes."},{"issue":"37","key":"10.1016\/j.jtemb.2026.127816_bib45","doi-asserted-by":"crossref","first-page":"62414","DOI":"10.18632\/oncotarget.18620","article-title":"A meta-analysis of Hashimoto's thyroiditis and papillary thyroid carcinoma risk","volume":"8","author":"Lai","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.jtemb.2026.127816_bib46","doi-asserted-by":"crossref","DOI":"10.1038\/s41371-025-00990-1","article-title":"PERSPECTIVE - The Growing Global Benefits of Limiting Salt Intake: an urgent call from the World Hypertension League for more effective policy and public health initiatives","author":"Egan","year":"2025","journal-title":"J. Hum. Hypertens."},{"issue":"7","key":"10.1016\/j.jtemb.2026.127816_bib47","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1089\/thy.2018.0034","article-title":"Urinary Iodine Concentration and Mortality Among U.S. Adults","volume":"28","author":"Inoue","year":"2018","journal-title":"Thyroid"},{"key":"10.1016\/j.jtemb.2026.127816_bib48","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2023.1153462","article-title":"Associations between urinary iodine concentration and the prevalence of metabolic disorders: a cross-sectional study","volume":"14","author":"Shen","year":"2023","journal-title":"Front Endocrinol. (Lausanne)"},{"issue":"12","key":"10.1016\/j.jtemb.2026.127816_bib49","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1089\/thy.2019.0462","article-title":"Consequences of Iodine Deficiency and Excess in Pregnancy and Neonatal Outcomes: A Prospective Cohort Study in Rio de Janeiro, Brazil","volume":"30","author":"Silva de Morais","year":"2020","journal-title":"Thyroid"},{"issue":"3","key":"10.1016\/j.jtemb.2026.127816_bib50","first-page":"603","article-title":"Potential role of iodine excess in papillary thyroid cancer and benign thyroid tumor: a case-control study","volume":"29","author":"Hou","year":"2020","journal-title":"Asia Pac. J. Clin. Nutr."},{"key":"10.1016\/j.jtemb.2026.127816_bib51","doi-asserted-by":"crossref","DOI":"10.1007\/s12020-023-03413-8","article-title":"Iodine status and its association with prevalence of thyroid diseases in adults from Jiangxi Province, China","author":"Yan","year":"2023","journal-title":"Endocrine"},{"key":"10.1016\/j.jtemb.2026.127816_bib52","article-title":"The relationship between urinary iodine concentration and papillary thyroid cancer: a systematic review and meta-analysis","volume":"13","author":"Zhang","year":"2022","journal-title":"Front. Endocrinol."},{"issue":"20","key":"10.1016\/j.jtemb.2026.127816_bib53","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000006734","article-title":"The relationship between iodine intake and the risk of thyroid cancer: a meta-analysis","volume":"96","author":"Cao","year":"2017","journal-title":"Medicine"},{"issue":"20","key":"10.1016\/j.jtemb.2026.127816_bib54","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.21037\/atm-21-4928","article-title":"Iodine intake level and incidence of thyroid disease in adults in Shaanxi province: a cross-sectional study","volume":"9","author":"Yu","year":"2021","journal-title":"Ann. Transl. Med"},{"issue":"2","key":"10.1016\/j.jtemb.2026.127816_bib55","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1007\/s00394-016-1370-2","article-title":"Iodine intake as a risk factor for BRAF mutations in papillary thyroid cancer patients from an iodine-replete area","volume":"57","author":"Kim","year":"2017","journal-title":"Eur. J. Nutr."},{"issue":"5","key":"10.1016\/j.jtemb.2026.127816_bib56","doi-asserted-by":"crossref","first-page":"401","DOI":"10.5603\/EP.a2019.0025","article-title":"BRAF V600E mutation in papillary thyroid cancer is correlated with adverse clinicopathological features but not with iodine exposure","volume":"70","author":"\u00d6z\u00e7elik","year":"2019","journal-title":"Endokrynol. Pol."},{"issue":"1","key":"10.1016\/j.jtemb.2026.127816_bib57","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1007\/s12020-020-02587-9","article-title":"Relationship between TSHR, BRAF and PIK3CA gene copy number variations and thyroid nodules","volume":"73","author":"Shi","year":"2021","journal-title":"Endocrine"},{"issue":"7","key":"10.1016\/j.jtemb.2026.127816_bib58","doi-asserted-by":"crossref","first-page":"2584","DOI":"10.1210\/endo.143.7.8914","article-title":"Radiationinduced thyroid carcinogenesis as a function of time and dietary iodine supply: an in vivo model of tumorigenesis in the rat","volume":"143","author":"Boltze","year":"2002","journal-title":"Endocrinology"},{"issue":"4","key":"10.1016\/j.jtemb.2026.127816_bib59","doi-asserted-by":"crossref","DOI":"10.1042\/BSR20170678","article-title":"Higher urinary bisphenol A concentration and excessive iodine intake are associated with nodular goiter and papillary thyroid carcinoma","volume":"37","author":"Zhou","year":"2017","journal-title":"Biosci. Rep."},{"issue":"12","key":"10.1016\/j.jtemb.2026.127816_bib60","doi-asserted-by":"crossref","first-page":"3180","DOI":"10.18632\/aging.101143","article-title":"Effect of the micronutrient iodine in thyroid carcinoma angiogenesis","volume":"8","author":"Daniell","year":"2016","journal-title":"Aging"},{"issue":"4","key":"10.1016\/j.jtemb.2026.127816_bib61","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1093\/labmed\/lmab117","article-title":"Validation of a spectrophotometric method for urinary iodine determination on microplate based on Sandell-Kolthoff reaction","volume":"53","author":"Oblak","year":"2022","journal-title":"Lab Med."}],"container-title":["Journal of Trace Elements in Medicine and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0946672X26000027?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0946672X26000027?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T07:18:25Z","timestamp":1769584705000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0946672X26000027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":61,"alternative-id":["S0946672X26000027"],"URL":"https:\/\/doi.org\/10.1016\/j.jtemb.2026.127816","relation":{},"ISSN":["0946-672X"],"issn-type":[{"value":"0946-672X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of iodine nutritional status with thyroid nodules and papillary thyroid carcinoma in women from an iodine-sufficient region in Brazil: A cross-sectional center study","name":"articletitle","label":"Article Title"},{"value":"Journal of Trace Elements in Medicine and Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtemb.2026.127816","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier GmbH.","name":"copyright","label":"Copyright"}],"article-number":"127816"}}