{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T10:55:09Z","timestamp":1791284109288,"version":"4.1.0"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Trace Elements in Medicine and Biology"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.jtemb.2026.127969","type":"journal-article","created":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T15:27:28Z","timestamp":1790954848000},"page":"127969","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Investigation of molecular effects of beta caryophyllene in cadmium-induced nephrotoxicity model in rats: in silico and in vivo studies"],"prefix":"10.1016","volume":"98","author":[{"given":"Yavuz Selim","family":"Sa\u011flam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bet\u00fcl","family":"Orhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burak","family":"\u00c7inar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berrah","family":"G\u00f6zegi\u0307r","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selim","family":"\u00c7omakli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samet","family":"Teki\u0307n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merve","family":"Bolat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0130smail","family":"Bolat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtemb.2026.127969_bib1","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.neuro.2025.04.006","article-title":"\u03b2-Caryophyllene attenuates cadmium induced neurotoxicity in rats by modulating different cellular signaling pathways","volume":"108","author":"Bolat","year":"2025","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.jtemb.2026.127969_bib2","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1080\/02652030903081937","article-title":"The European maximum level for cadmium in bovine kidneys is in Belgium only realistic for cattle up to 2 years of age","volume":"26","author":"Waegeneers","year":"2009","journal-title":"Food Addit. Contam. Part. A"},{"key":"10.1016\/j.jtemb.2026.127969_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2025.114816","article-title":"Syringic acid alleviates cadmium-induced neurotoxicity in rats by modulating cellular signaling pathways","volume":"158","author":"Bolat","year":"2025","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.jtemb.2026.127969_bib4","doi-asserted-by":"crossref","first-page":"19","DOI":"10.5152\/VetSciPract.2023.222441","article-title":"Investigation of neurotoxicity oxidative stress and oxidative DNA damage in cadmium-induced brain injury in rats","volume":"18","author":"BOLAT","year":"2023","journal-title":"Vet. Sci. Pract."},{"key":"10.1016\/j.jtemb.2026.127969_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2020.117324","article-title":"Oleic acid protects against cadmium induced cardiac and hepatic tissue injury in male Wistar rats: a mechanistic study","volume":"244","author":"Bhattacharjee","year":"2020","journal-title":"Life Sci."},{"key":"10.1016\/j.jtemb.2026.127969_bib6","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1248\/bpb.b212014","article-title":"Cadmium renal toxicity via apoptotic pathways","volume":"35","author":"Fujiwara","year":"2012","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.jtemb.2026.127969_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.tox.2022.153339","article-title":"The mechanism of the cadmium-induced toxicity and cellular response in the liver","volume":"480","author":"Souza-Arroyo","year":"2022","journal-title":"Toxicology"},{"key":"10.1016\/j.jtemb.2026.127969_bib8","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1515\/reveh-2019-0016","article-title":"Cadmium toxicity: effects on human reproduction and fertility","volume":"34","author":"Kumar","year":"2019","journal-title":"Rev. Environ. Health"},{"key":"10.1016\/j.jtemb.2026.127969_bib9","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1016\/j.toxrep.2018.05.012","article-title":"Toxicodynamics of lead, cadmium, mercury and arsenic- induced kidney toxicity and treatment strategy: a mini review","volume":"5","author":"Rana","year":"2018","journal-title":"Toxicol. Rep."},{"key":"10.1016\/j.jtemb.2026.127969_bib10","doi-asserted-by":"crossref","unstructured":"F. Th\u00e9venod, W.-K. Lee, Toxicology of Cadmium and Its Damage to Mammalian Organs, in: 2013: pp. 415\u2013490. https:\/\/doi.org\/10.1007\/978-94-007-5179-8_14.","DOI":"10.1007\/978-94-007-5179-8_14"},{"key":"10.1016\/j.jtemb.2026.127969_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2021.111862","article-title":"Quercetin alleviates cadmium chloride-induced renal damage in rats by suppressing endoplasmic reticulum stress through SIRT1-dependent deacetylation of Xbp-1s and eIF2\u03b1","volume":"141","author":"Alshammari","year":"2021","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.jtemb.2026.127969_bib12","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1007\/s10534-010-9329-x","article-title":"Cadmium stress: an oxidative challenge","volume":"23","author":"Cuypers","year":"2010","journal-title":"BioMetals"},{"key":"10.1016\/j.jtemb.2026.127969_bib13","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1007\/s10534-010-9328-y","article-title":"Heavy metal poisoning: the effects of cadmium on the kidney","volume":"23","author":"Johri","year":"2010","journal-title":"BioMetals"},{"key":"10.1016\/j.jtemb.2026.127969_bib14","doi-asserted-by":"crossref","first-page":"3007","DOI":"10.1002\/cam4.816","article-title":"\u03b2 -caryophyllene and \u03b2 -caryophyllene oxide\u2014natural compounds of anticancer and analgesic properties","volume":"5","author":"Fidyt","year":"2016","journal-title":"Cancer Med."},{"key":"10.1016\/j.jtemb.2026.127969_bib15","doi-asserted-by":"crossref","first-page":"10262","DOI":"10.1002\/jcb.27369","article-title":"\u03b2-Caryophyllene, the major constituent of copaiba oil, reduces systemic inflammation and oxidative stress in arthritic rats","volume":"119","author":"Ames-Sibin","year":"2018","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.jtemb.2026.127969_bib16","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.3390\/molecules30081751","article-title":"The potential therapeutic role of beta-caryophyllene as a chemosensitizer and an inhibitor of angiogenesis in cancer","volume":"30","author":"Ahmed","year":"2025","journal-title":"Molecules"},{"key":"10.1016\/j.jtemb.2026.127969_bib17","doi-asserted-by":"crossref","first-page":"49","DOI":"10.33073\/pjm-2020-007","article-title":"Antibacterial activity and mode of action of \u03b2-caryophyllene on Bacillus cereus","volume":"69","author":"MOO","year":"2020","journal-title":"Pol. J. Microbiol."},{"key":"10.1016\/j.jtemb.2026.127969_bib18","doi-asserted-by":"crossref","first-page":"2376","DOI":"10.1002\/ptr.6199","article-title":"A systematic review on the neuroprotective perspectives of beta-caryophyllene","volume":"32","author":"da","year":"2018","journal-title":"Phyther. Res."},{"key":"10.1016\/j.jtemb.2026.127969_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2023.107013","article-title":"IUPHAR review- preclinical models of neuropathic pain: evaluating multifunctional properties of natural cannabinoid receptors ligands","volume":"199","author":"Benamar","year":"2024","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.jtemb.2026.127969_bib20","first-page":"1","article-title":"Protective effects of curcumin against valproic acid induced brain kidney and liver damage in rats","author":"Terim Kapakin","year":"2024","journal-title":"Drug. Chem. Toxicol."},{"key":"10.1016\/j.jtemb.2026.127969_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.smallrumres.2023.107171","article-title":"Investigation of the effects of pulmonary adenomatosis on oxidative dna damage, inflammation, apoptosis, and autophagy in lung tissues in sheep","volume":"230","author":"Bolat","year":"2024","journal-title":"Small Rumin. Res."},{"key":"10.1016\/j.jtemb.2026.127969_bib22","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jcpa.2024.11.001","article-title":"Cellular pathophysiology of Leptospira interrogans infection in canine testicular tissue: role of the TLR4\/NF-kB\/JNK pathway","volume":"216","author":"Bolat","year":"2025","journal-title":"J. Comp. Pathol."},{"key":"10.1016\/j.jtemb.2026.127969_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2024.107186","article-title":"Differential TLR2 and TLR4 mediated inflammatory and apoptotic responses in asymptomatic and symptomatic Leptospira interrogans infections in canine uterine tissue","volume":"198","author":"Bolat","year":"2025","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.jtemb.2026.127969_bib24","doi-asserted-by":"crossref","DOI":"10.1007\/s00210-025-03996-1","article-title":"Gallic acid\u2019s protective mechanisms against acrylamide-induced pulmonary injury: in vivo and in silico insights into the Nrf-2\/HO-1\/NF\u03baB pathway modulation","author":"Bolat","year":"2025","journal-title":"Naunyn. Schmiede Arch. Pharmacol."},{"key":"10.1016\/j.jtemb.2026.127969_bib25","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2021.650930","article-title":"Cadmium, an environmental contaminant, exacerbates alzheimer\u2019s pathology in the aged mice\u2019s brain","volume":"13","author":"Ali","year":"2021","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.jtemb.2026.127969_bib26","doi-asserted-by":"crossref","first-page":"274","DOI":"10.3390\/ijerph16020274","article-title":"Toxic effect of acute cadmium and lead exposure in rat blood, liver, and kidney","volume":"16","author":"Andjelkovic","year":"2019","journal-title":"Int. J. Environ. Res. Public. Health"},{"key":"10.1016\/j.jtemb.2026.127969_bib27","doi-asserted-by":"crossref","DOI":"10.30954\/2277-940X.03.2020.23","article-title":"Cadmium (Cd) and chlorpyrifos (CPF) induced pulmonary toxicity in wistar rats","volume":"10","author":"Yadala","year":"2020","journal-title":"J. Anim. Res."},{"key":"10.1016\/j.jtemb.2026.127969_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2021.119610","article-title":"Modulatory effects of carvacrol against cadmium-induced hepatotoxicity and nephrotoxicity by molecular targeting regulation","volume":"277","author":"Kandemir","year":"2021","journal-title":"Life Sci."},{"key":"10.1016\/j.jtemb.2026.127969_bib29","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1016\/j.freeradbiomed.2012.01.014","article-title":"\u03b2-Caryophyllene ameliorates cisplatin-induced nephrotoxicity in a cannabinoid 2 receptor-dependent manner","volume":"52","author":"Horv\u00e1th","year":"2012","journal-title":"Free. Radic. Biol. Med."},{"key":"10.1016\/j.jtemb.2026.127969_bib30","doi-asserted-by":"crossref","DOI":"10.1002\/jbt.22891","article-title":"\u03b2-Caryophyllene may attenuate hyperoxaluria-induced kidney dysfunction in rats by regulating stress marker KIM-1\/MCP-1 and NF-\u03baB signaling pathway","volume":"35","author":"Xu","year":"2021","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"10.1016\/j.jtemb.2026.127969_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2022.120971","article-title":"The role of inflammation in cadmium nephrotoxicity: NF-\u03baB comes into view","volume":"308","author":"Hassanein","year":"2022","journal-title":"Life Sci."},{"key":"10.1016\/j.jtemb.2026.127969_bib32","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s12011-015-0453-x","article-title":"Thymoquinone ameliorates cadmium-induced nephrotoxicity, apoptosis, and oxidative stress in rats is based on its anti-apoptotic and anti-oxidant properties","volume":"170","author":"Erboga","year":"2016","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.jtemb.2026.127969_bib33","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1152\/physrev.00023.2017","article-title":"The KEAP1-NRF2 system: a thiol-based sensor-effector apparatus for maintaining redox homeostasis","volume":"98","author":"Yamamoto","year":"2018","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.jtemb.2026.127969_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.tice.2024.102576","article-title":"Attenuation of inflammation, oxidative stress and TGF-\u03b21\/Smad3 signaling and upregulation of Nrf2\/HO-1 signaling mediate the protective effect of diallyl disulfide against cadmium nephrotoxicity","volume":"91","author":"Alruhaimi","year":"2024","journal-title":"Tissue Cell."},{"key":"10.1016\/j.jtemb.2026.127969_bib35","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1177\/1753425908101521","article-title":"Activation of toll-like receptors 2 and 4 in Aspergillus fumigatus keratitis","volume":"15","author":"Jie Zhao","year":"2009","journal-title":"Innate Immun."},{"key":"10.1016\/j.jtemb.2026.127969_bib36","doi-asserted-by":"crossref","first-page":"6252","DOI":"10.3390\/ijms23116252","article-title":"Selenium antagonizes cadmium-induced inflammation and oxidative stress via suppressing the interplay between NLRP3 inflammasome and HMGB1\/NF-\u03baB pathway in duck hepatocytes","volume":"23","author":"Cao","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jtemb.2026.127969_bib37","doi-asserted-by":"crossref","first-page":"5825","DOI":"10.1038\/s41598-019-42368-7","article-title":"Royal jelly attenuates cadmium-induced nephrotoxicity in male mice","volume":"9","author":"Almeer","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jtemb.2026.127969_bib38","doi-asserted-by":"crossref","first-page":"4176","DOI":"10.3390\/molecules24224176","article-title":"Carnosic acid attenuates cadmium induced nephrotoxicity by inhibiting oxidative stress, promoting Nrf2\/HO-1 signalling and impairing TGF-\u03b21\/smad\/collagen IV signalling","volume":"24","author":"Das","year":"2019","journal-title":"Molecules"},{"key":"10.1016\/j.jtemb.2026.127969_bib39","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.3390\/life12081150","article-title":"Renoprotective and oxidative stress-modulating effects of taxifolin against cadmium-induced nephrotoxicity in mice","volume":"12","author":"Algefare","year":"2022","journal-title":"Life"},{"key":"10.1016\/j.jtemb.2026.127969_bib40","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-23842-1","article-title":"\u03b2-caryophyllene and docosahexaenoic acid, isolated or associated, have potential antinociceptive and anti-inflammatory effects in vitro and in vivo","volume":"12","author":"Sousa","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jtemb.2026.127969_bib41","first-page":"1382","article-title":"The investigation of the effect of fraxin on hepatotoxicity induced by cisplatin in rats","volume":"23","author":"Ekinci-Akdemi R","year":"2020","journal-title":"Iran. J. Basic. Med. Sci."},{"key":"10.1016\/j.jtemb.2026.127969_bib42","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.lfs.2016.01.038","article-title":"Molecular and biochemical evidence on the protective effects of embelin and carnosic acid in isoproterenol-induced acute myocardial injury in rats","volume":"147","author":"Kocak","year":"2016","journal-title":"Life Sci."},{"key":"10.1016\/j.jtemb.2026.127969_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.gene.2023.147502","article-title":"Beneficial effects of chrysin on cadmium-induced nephrotoxicity in rats: modulating the levels of Nrf2\/HO-1, RAGE\/NLRP3, and Caspase-3\/Bax\/Bcl-2 signaling pathways","volume":"875","author":"\u015eim\u015fek","year":"2023","journal-title":"Gene"},{"key":"10.1016\/j.jtemb.2026.127969_bib44","doi-asserted-by":"crossref","unstructured":"H. Su, C. Wan, A. Song, Y. Qiu, W. Xiong, C. Zhang, Oxidative Stress and Renal Fibrosis: Mechanisms and Therapies, in: 2019: pp. 585\u2013604. https:\/\/doi.org\/10.1007\/978-981-13-8871-2_29.","DOI":"10.1007\/978-981-13-8871-2_29"},{"key":"10.1016\/j.jtemb.2026.127969_bib45","doi-asserted-by":"crossref","first-page":"2043","DOI":"10.1039\/C9MT00227H","article-title":"Trehalose alleviates cadmium-induced brain damage by ameliorating oxidative stress, autophagy inhibition, and apoptosis","volume":"11","author":"Tang","year":"2019","journal-title":"Metallomics"},{"key":"10.1016\/j.jtemb.2026.127969_bib46","doi-asserted-by":"crossref","DOI":"10.1002\/jbt.23670","article-title":"Cadmium neurotoxicity and therapeutic strategies","volume":"38","author":"Wen","year":"2024","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"10.1016\/j.jtemb.2026.127969_bib47","doi-asserted-by":"crossref","first-page":"2963","DOI":"10.3390\/nu12102963","article-title":"Therapeutic potential of \u03b2-caryophyllene: a dietary cannabinoid in diabetes and associated complications","volume":"12","author":"Hashiesh","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.jtemb.2026.127969_bib48","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1007\/s11011-022-00945-2","article-title":"Neuroprotective effects of carvacrol against cadmium-induced neurotoxicity in rats: role of oxidative stress, inflammation and apoptosis","volume":"37","author":"Y\u0131ld\u0131z","year":"2022","journal-title":"Metab. Brain Dis."},{"key":"10.1016\/j.jtemb.2026.127969_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.122805","article-title":"Environment-relevant concentrations of cadmium induces necroptosis and inflammation; baicalein maintains gill homeostasis through suppressing ROS\/ER stress signaling in common carps (Cyprinus carpio L.)","volume":"340","author":"Li","year":"2024","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.jtemb.2026.127969_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2023.110410","article-title":"Zingerone reduces sodium arsenite-induced nephrotoxicity by regulating oxidative stress, inflammation, apoptosis and histopathological changes","volume":"374","author":"Akaras","year":"2023","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.jtemb.2026.127969_bib51","doi-asserted-by":"crossref","first-page":"5979","DOI":"10.3390\/ijms24065979","article-title":"Cadmium disrupted ER Ca2+ homeostasis by inhibiting SERCA2 expression and activity to induce apoptosis in renal proximal tubular cells","volume":"24","author":"Li","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jtemb.2026.127969_bib52","doi-asserted-by":"crossref","first-page":"9099","DOI":"10.1073\/pnas.0803601105","article-title":"Beta-caryophyllene is a dietary cannabinoid","volume":"105","author":"Gertsch","year":"2008","journal-title":"Proc. Natl. Acad. Sci."}],"container-title":["Journal of Trace Elements in Medicine and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0946672X26001550?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0946672X26001550?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T10:32:57Z","timestamp":1791282777000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0946672X26001550"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":52,"alternative-id":["S0946672X26001550"],"URL":"https:\/\/doi.org\/10.1016\/j.jtemb.2026.127969","relation":{},"ISSN":["0946-672X"],"issn-type":[{"value":"0946-672X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Investigation of molecular effects of beta caryophyllene in cadmium-induced nephrotoxicity model in rats: in silico and in vivo studies","name":"articletitle","label":"Article Title"},{"value":"Journal of Trace Elements in Medicine and Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtemb.2026.127969","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier GmbH. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"127969"}}