{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T09:10:09Z","timestamp":1784365809524,"version":"3.55.0"},"reference-count":74,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["jthjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Thrombosis and Haemostasis"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1016\/j.jtha.2022.11.032","type":"journal-article","created":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T10:24:17Z","timestamp":1674642257000},"page":"691-699","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"title":["Communication from the Scientific Standardization Committees of the International Society on Thrombosis and Haemostasis on vascular endothelium-related biomarkers in disseminated intravascular coagulation"],"prefix":"10.1016","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0255-4088","authenticated-orcid":false,"given":"Toshiaki","family":"Iba","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3766-4962","authenticated-orcid":false,"given":"Jerrold H.","family":"Levy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7218-0993","authenticated-orcid":false,"given":"Jecko","family":"Thachil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5953-163X","authenticated-orcid":false,"given":"Sophie","family":"Susen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2212-5299","authenticated-orcid":false,"given":"Marcel","family":"Levi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5556-3623","authenticated-orcid":false,"given":"Ecaterina","family":"Scarlatescu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtha.2022.11.032_bib1","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1055\/s-0034-1395155","article-title":"A\u00a0short contemporary history of disseminated intravascular coagulation","volume":"40","author":"Levi","year":"2014","journal-title":"Semin Thromb Hemost"},{"key":"10.1016\/j.jtha.2022.11.032_bib2","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1055\/s-0037-1616068","article-title":"Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation","volume":"86","author":"Taylor","year":"2001","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jtha.2022.11.032_bib3","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1007\/s00134-013-2993-x","article-title":"Microparticles are new biomarkers of septic shock-induced disseminated intravascular coagulopathy","volume":"39","author":"Delabranche","year":"2013","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jtha.2022.11.032_bib4","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1177\/0885066620949131","article-title":"Plasma endothelial glycocalyx components as a potential biomarker for predicting the development of disseminated intravascular coagulation in patients with sepsis","volume":"36","author":"Huang","year":"2021","journal-title":"J\u00a0Intensive Care Med"},{"key":"10.1016\/j.jtha.2022.11.032_bib5","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.thromres.2019.04.025","article-title":"Role of disseminated intravascular coagulation in severe sepsis","volume":"178","author":"Gando","year":"2019","journal-title":"Thromb Res"},{"key":"10.1016\/j.jtha.2022.11.032_bib6","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1097\/01.CCM.0000202209.42491.38","article-title":"A\u00a0multicenter, prospective validation of disseminated intravascular coagulation diagnostic criteria for critically ill patients: comparing current criteria","volume":"34","author":"Gando","year":"2006","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jtha.2022.11.032_bib7","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1111\/jth.14482","article-title":"Scientific and Standardization Committee on DIC of the International Society on Thrombosis and Haemostasis. Proposal of a two-step process for the diagnosis of sepsis-induced disseminated intravascular coagulation","volume":"17","author":"Iba","year":"2019","journal-title":"J\u00a0Thromb Haemost"},{"key":"10.1016\/j.jtha.2022.11.032_bib8","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2017-017046","article-title":"New criteria for sepsis-induced coagulopathy (SIC) following the revised sepsis definition: a retrospective analysis of a nationwide survey","volume":"7","author":"Iba","year":"2017","journal-title":"BMJ Open"},{"key":"10.1016\/j.jtha.2022.11.032_bib9","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1164\/rccm.201910-1911TR","article-title":"Endothelial responses in sepsis","volume":"202","author":"Joffre","year":"2020","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jtha.2022.11.032_bib10","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1111\/jth.14371","article-title":"Derangement of the endothelial glycocalyx in sepsis","volume":"17","author":"Iba","year":"2019","journal-title":"J\u00a0Thromb Haemost"},{"key":"10.1016\/j.jtha.2022.11.032_bib11","doi-asserted-by":"crossref","first-page":"6743","DOI":"10.1182\/blood-2011-07-343566","article-title":"Leukocyte ligands for endothelial selectins: specialized glycoconjugates that mediate rolling and signaling under flow","volume":"118","author":"Zarbock","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2022.11.032_bib12","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1023\/A:1026016628386","article-title":"Platelet endothelial cell adhesion molecule in\u00a0cell signaling and thrombosis","volume":"253","author":"Gong","year":"2003","journal-title":"Mol Cell Biochem"},{"key":"10.1016\/j.jtha.2022.11.032_bib13","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1177\/1358863X15591201","article-title":"Soluble vascular endothelial-cadherin and auto-antibodies to human vascular endothelial-cadherin in human diseases: two new biomarkers of endothelial dysfunction","volume":"20","author":"Blaise","year":"2015","journal-title":"Vasc Med"},{"key":"10.1016\/j.jtha.2022.11.032_bib14","doi-asserted-by":"crossref","first-page":"9611","DOI":"10.3390\/ijms22179611","article-title":"Utility of platelet endothelial cell adhesion molecule 1 in the platelet activity assessment in mouse and human blood","volume":"22","author":"Marcinczyk","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jtha.2022.11.032_bib15","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1097\/SHK.0b013e3182903f0d","article-title":"Biomarkers of endothelial cell activation in early sepsis","volume":"39","author":"Skibsted","year":"2013","journal-title":"Shock"},{"key":"10.1016\/j.jtha.2022.11.032_bib16","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.cyto.2016.08.028","article-title":"Endothelial adhesion molecules and multiple organ failure in patients with severe sepsis","volume":"88","author":"Amalakuhan","year":"2016","journal-title":"Cytokine"},{"key":"10.1016\/j.jtha.2022.11.032_bib17","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.thromres.2004.09.022","article-title":"Serial changes in neutrophil-endothelial activation markers during the course of sepsis associated with disseminated intravascular coagulation","volume":"116","author":"Gando","year":"2005","journal-title":"Thromb Res"},{"key":"10.1016\/j.jtha.2022.11.032_bib18","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.tcm.2007.02.002","article-title":"Endothelial glycocalyx: sweet shield of blood vessels","volume":"17","author":"Van Teeffelen","year":"2007","journal-title":"Trends Cardiovasc Med"},{"key":"10.1016\/j.jtha.2022.11.032_bib19","first-page":"259","volume":"45","author":"Ince","year":"2016","journal-title":"The endothelium in sepsis"},{"key":"10.1016\/j.jtha.2022.11.032_bib20","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1111\/bcp.12629","article-title":"Degradation of the endothelial glycocalyx in clinical settings: searching for the sheddases","volume":"80","author":"Becker","year":"2015","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.jtha.2022.11.032_bib21","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/s40560-016-0182-z","article-title":"Glycocalyx and its involvement in clinical pathophysiologies","volume":"4","author":"Ushiyama","year":"2016","journal-title":"J\u00a0Intensive Care"},{"key":"10.1016\/j.jtha.2022.11.032_bib22","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s11897-017-0320-5","article-title":"Endothelial glycocalyx as biomarker for cardiovascular diseases: mechanistic and clinical implications","volume":"14","author":"Kim","year":"2017","journal-title":"Curr Heart Fail Rep"},{"key":"10.1016\/j.jtha.2022.11.032_bib23","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1111\/apm.12662","article-title":"Circulating syndecans during critical illness","volume":"125","author":"Nelson","year":"2017","journal-title":"APMIS"},{"key":"10.1016\/j.jtha.2022.11.032_bib24","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.jcrc.2017.07.001","article-title":"Endothelial glycocalyx biomarkers increase in patients with infection during Emergency Department treatment","volume":"42","author":"Smart","year":"2017","journal-title":"J\u00a0Crit Care"},{"key":"10.1016\/j.jtha.2022.11.032_bib25","first-page":"177","article-title":"CD138 (syndecan-1) expression in health and disease","volume":"29","author":"Palaiologou","year":"2014","journal-title":"Histol Histopathol"},{"key":"10.1016\/j.jtha.2022.11.032_bib26","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/s40560-018-0340-6","article-title":"Role of extracellular vesicles in the development of sepsis-induced coagulopathy","volume":"6","author":"Iba","year":"2018","journal-title":"J\u00a0Intensive Care"},{"key":"10.1016\/j.jtha.2022.11.032_bib27","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.4244\/EIJY14M10_02","article-title":"Improved endothelial function and decreased levels of endothelium-derived microparticles after transcatheter aortic valve implantation","volume":"10","author":"Horn","year":"2015","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jtha.2022.11.032_bib28","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0169976","article-title":"Non-lethal endotoxin injection: a rat model of hypercoagulability","volume":"12","author":"Brooks","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.jtha.2022.11.032_bib29","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/s00441-008-0710-9","article-title":"Endothelial microparticles in diseases","volume":"335","author":"Chironi","year":"2009","journal-title":"Cell Tissue Res"},{"issue":"4","key":"10.1016\/j.jtha.2022.11.032_bib30","first-page":"823","article-title":"Enhanced production of endothelial microparticles with increased binding to leukocytes in patients with severe systemic inflammatory response syndrome","volume":"56","author":"Ogura","year":"2004","journal-title":"J\u00a0Trauma"},{"key":"10.1016\/j.jtha.2022.11.032_bib31","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1097\/SHK.0000000000000657","article-title":"Characterization of microvesicles in septic shock using high-sensitivity flow cytometry","volume":"46","author":"Lehner","year":"2016","journal-title":"Shock"},{"key":"10.1016\/j.jtha.2022.11.032_bib32","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1055\/s-2001-18867","article-title":"Fibrinolysis in disseminated intravascular coagulation","volume":"27","author":"Hack","year":"2001","journal-title":"Semin Thromb Hemost"},{"key":"10.1016\/j.jtha.2022.11.032_bib33","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/s40560-017-0238-8","article-title":"Usefulness of plasminogen activator inhibitor-1 as a predictive marker of mortality in sepsis","volume":"5","author":"Hoshino","year":"2017","journal-title":"J\u00a0Intensive Care"},{"key":"10.1016\/j.jtha.2022.11.032_bib34","doi-asserted-by":"crossref","first-page":"19095","DOI":"10.1016\/S0021-9258(17)32279-2","article-title":"Induction of plasminogen activator inhibitor-1 in HepG2 human hepatoma cells by mediators of the acute phase response","volume":"269","author":"Healy","year":"1994","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jtha.2022.11.032_bib35","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1097\/00003246-200106000-00015","article-title":"An enhanced fibrinolysis prevents the development of multiple organ failure in disseminated intravascular coagulation in spite of much activation of blood coagulation","volume":"29","author":"Asakura","year":"2001","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jtha.2022.11.032_bib36","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1055\/s-0033-1334140","article-title":"Role of fibrinolysis in sepsis","volume":"39","author":"Gando","year":"2013","journal-title":"Semin Thromb Hemost"},{"key":"10.1016\/j.jtha.2022.11.032_bib37","doi-asserted-by":"crossref","first-page":"2520","DOI":"10.1182\/blood.V76.12.2520.2520","article-title":"Experimental endotoxemia in humans: analysis of cytokine release and coagulation, fibrinolytic, and complement pathways","volume":"76","author":"van Deventer","year":"1990","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2022.11.032_bib38","doi-asserted-by":"crossref","first-page":"R13","DOI":"10.1186\/cc13190","article-title":"Combination of thrombin-antithrombin complex, plasminogen activator inhibitor-1, and protein C activity for early identification of severe coagulopathy in initial phase of sepsis: a prospective observational study","volume":"18","author":"Koyama","year":"2014","journal-title":"Crit Care"},{"key":"10.1016\/j.jtha.2022.11.032_bib39","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1161\/01.ATV.13.5.669","article-title":"Plasminogen activator inhibitor-1 mRNA is expressed in platelets and megakaryocytes and the megakaryoblastic cell line CHRF-288","volume":"13","author":"Konkle","year":"1993","journal-title":"Arterioscler Thromb"},{"key":"10.1016\/j.jtha.2022.11.032_bib40","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1177\/107602960100700309","article-title":"Plasma levels of total plasminogen activator inhibitor-I (PAI-I) and tPA\/PAI-1 complex in patients with disseminated intravascular coagulation and thrombotic thrombocytopenic purpura","volume":"7","author":"Watanabe","year":"2001","journal-title":"Clin Appl Thromb Hemost"},{"key":"10.1016\/j.jtha.2022.11.032_bib41","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1160\/TH15-08-0687","article-title":"Antithrombin: anti-inflammatory properties and clinical applications","volume":"115","author":"Levy","year":"2016","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jtha.2022.11.032_bib42","doi-asserted-by":"crossref","first-page":"e129","DOI":"10.1016\/j.thromres.2012.03.021","article-title":"Efficacy and bleeding risk of antithrombin supplementation in septic disseminated intravascular coagulation: a prospective multicenter survey","volume":"130","author":"Iba","year":"2012","journal-title":"Thromb Res"},{"key":"10.1016\/j.jtha.2022.11.032_bib43","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/s40560-021-00555-7","article-title":"The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020)","volume":"9","author":"Egi","year":"2021","journal-title":"J\u00a0Intensive Care"},{"key":"10.1016\/j.jtha.2022.11.032_bib44","doi-asserted-by":"crossref","first-page":"R272","DOI":"10.1186\/cc10553","article-title":"Disseminated intravascular coagulation or acute coagulopathy of trauma shock early after trauma? An observational study","volume":"15","author":"Johansson","year":"2011","journal-title":"Crit Care"},{"key":"10.1016\/j.jtha.2022.11.032_bib45","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1034\/j.1600-0609.2001.5790508.x","article-title":"Decreased plasma activity of antithrombin or protein C is not due to consumption coagulopathy in septic patients with disseminated intravascular coagulation","volume":"67","author":"Asakura","year":"2001","journal-title":"Eur J Haematol"},{"key":"10.1016\/j.jtha.2022.11.032_bib46","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1097\/01.shk.0000239762.90335.68","article-title":"Serum albumin levels anticipate antithrombin III activities before and after antithrombin III agent in critical patients with disseminated intravascular coagulation","volume":"27","author":"Aibiki","year":"2007","journal-title":"Shock"},{"key":"10.1016\/j.jtha.2022.11.032_bib47","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s12959-018-0171-7","article-title":"Decreased antithrombin activity in the early phase of trauma is strongly associated with extravascular leakage, but not with antithrombin consumption: a prospective observational study","volume":"16","author":"Matsumoto","year":"2018","journal-title":"Thromb J"},{"key":"10.1016\/j.jtha.2022.11.032_bib48","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.ejcts.2005.12.015","article-title":"Antithrombin activity in children with chylothorax","volume":"29","author":"Bernet-Buettiker","year":"2006","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.jtha.2022.11.032_bib49","first-page":"1093","article-title":"Predicting the severity of systemic inflammatory response syndrome (SIRS)-associated coagulopathy with hemostatic molecular markers and vascular endothelial injury markers","volume":"63","author":"Iba","year":"2007","journal-title":"J\u00a0Trauma"},{"key":"10.1016\/j.jtha.2022.11.032_bib50","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1097\/00003246-200202000-00001","article-title":"Predictive value of antithrombin III and serum C-reactive protein concentration in critically ill patients with suspected sepsis","volume":"30","author":"Pettila","year":"2002","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jtha.2022.11.032_bib51","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1097\/01.shk.0000144422.32647.b6","article-title":"Association between the severity of sepsis and the changes in hemostatic molecular markers and vascular endothelial damage markers","volume":"23","author":"Iba","year":"2005","journal-title":"Shock"},{"key":"10.1016\/j.jtha.2022.11.032_bib52","doi-asserted-by":"crossref","first-page":"85","DOI":"10.3343\/alm.2014.34.2.85","article-title":"Changes in plasma levels of natural anticoagulants in disseminated intravascular coagulation: high prognostic value of antithrombin and protein C in patients with underlying sepsis or severe infection","volume":"34","author":"Choi","year":"2014","journal-title":"Ann Lab Med"},{"key":"10.1016\/j.jtha.2022.11.032_bib53","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/s12959-016-0117-x","article-title":"DIC subcommittee of the Japanese Society on Thrombosis and Hemostasis. Proposal for new diagnostic criteria for DIC from the Japanese Society on Thrombosis and Hemostasis","volume":"14","author":"Asakura","year":"2016","journal-title":"Thromb J"},{"key":"10.1016\/j.jtha.2022.11.032_bib54","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/S0021-9258(19)68276-1","article-title":"Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C","volume":"257","author":"Esmon","year":"1982","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jtha.2022.11.032_bib55","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1182\/blood-2017-12-768994","article-title":"Exploring traditional and nontraditional roles for thrombomodulin","volume":"132","author":"Loghmani","year":"2018","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2022.11.032_bib56","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1084\/jem.20020077","article-title":"The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways","volume":"196","author":"Conway","year":"2002","journal-title":"J\u00a0Exp Med"},{"key":"10.1016\/j.jtha.2022.11.032_bib57","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1186\/s13054-019-2552-0","article-title":"Thrombomodulin in disseminated intravascular coagulation and other critical conditions-a multi-faceted anticoagulant protein with therapeutic potential","volume":"23","author":"Ito","year":"2019","journal-title":"Crit Care"},{"key":"10.1016\/j.jtha.2022.11.032_bib58","doi-asserted-by":"crossref","first-page":"2024","DOI":"10.1182\/blood.V76.10.2024.2024","article-title":"Plasma thrombomodulin in health and diseases","volume":"76","author":"Takano","year":"1990","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2022.11.032_bib59","first-page":"660","article-title":"Soluble thrombomodulin increases in patients with disseminated intravascular coagulation and in those with multiple organ dysfunction syndrome after trauma: role of neutrophil elastase","volume":"39","author":"Gando","year":"1995","journal-title":"J\u00a0Trauma"},{"key":"10.1016\/j.jtha.2022.11.032_bib60","doi-asserted-by":"crossref","first-page":"S12","DOI":"10.1097\/00003246-200009001-00004","volume":"28","author":"Taylor","year":"2000","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jtha.2022.11.032_bib61","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1055\/s-0037-1616753","volume":"86","author":"Wada","year":"2001","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jtha.2022.11.032_bib62","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/978-3-030-41769-7_18","article-title":"Physiological roles of the von Willebrand factor-factor VIII interaction","volume":"94","author":"Kiouptsi","year":"2020","journal-title":"Subcell Biochem"},{"key":"10.1016\/j.jtha.2022.11.032_bib63","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1111\/ijlh.13785","article-title":"Prognostic value of the ADAMTS13-vWF axis in disseminated intravascular coagulation: platelet count\/vWF: ag ratio as a strong prognostic marker","volume":"44","author":"Jang","year":"2022","journal-title":"Int J Lab Hematol"},{"key":"10.1016\/j.jtha.2022.11.032_bib64","doi-asserted-by":"crossref","DOI":"10.1177\/1076029619852163","article-title":"Endothelial dysfunction is associated with mortality and severity of coagulopathy in patients with sepsis and disseminated intravascular coagulation","volume":"25","author":"Walborn","year":"2019","journal-title":"Clin Appl Thromb Hemost"},{"key":"10.1016\/j.jtha.2022.11.032_bib65","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s12959-020-00231-0","article-title":"Disseminated intravascular coagulation: new identity as endotheliopathy-associated vascular microthrombotic disease based on in\u00a0vivo hemostasis and endothelial molecular pathogenesis","volume":"18","author":"Chang","year":"2020","journal-title":"Thromb J"},{"key":"10.1016\/j.jtha.2022.11.032_bib66","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1161\/ATVBAHA.122.317162","article-title":"Thromboinflammation: from atherosclerosis to COVID-19","volume":"42","author":"Wagner","year":"2022","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jtha.2022.11.032_bib67","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1182\/blood-2005-03-1087","article-title":"Severe secondary deficiency of von Willebrand factor-cleaving protease (ADAMTS13) in patients with sepsis-induced disseminated intravascular coagulation: its correlation with development of renal failure","volume":"107","author":"Ono","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2022.11.032_bib68","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s13054-018-2292-6","article-title":"The glycocalyx: a novel diagnostic and therapeutic target in sepsis","volume":"23","author":"Uchimido","year":"2019","journal-title":"Crit Care"},{"key":"10.1016\/j.jtha.2022.11.032_bib69","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1172\/JCI97488","article-title":"Tie2 protects the vasculature against thrombus formation in systemic inflammation","volume":"128","author":"Higgins","year":"2018","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.jtha.2022.11.032_bib70","doi-asserted-by":"crossref","first-page":"e46","DOI":"10.1371\/journal.pmed.0030046","article-title":"Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans. Version 2","volume":"3","author":"Parikh","year":"2006","journal-title":"PLoS Med"},{"key":"10.1016\/j.jtha.2022.11.032_bib71","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.chest.2017.01.010","article-title":"ProCESS Investigators. Endothelial permeability and hemostasis in septic shock: results from the ProCESS Trial","volume":"152","author":"Hou","year":"2017","journal-title":"Chest"},{"key":"10.1016\/j.jtha.2022.11.032_bib72","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1177\/1076029618786029","article-title":"Angiopoietin 2 levels in the risk stratification and mortality outcome prediction of sepsis-associated coagulopathy","volume":"24","author":"Statz","year":"2018","journal-title":"Clin Appl Thromb Hemost"},{"key":"10.1016\/j.jtha.2022.11.032_bib73","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1056\/NEJM199904013401303","article-title":"Annexin II and bleeding in acute promyelocytic leukemia","volume":"340","author":"Menell","year":"1999","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jtha.2022.11.032_bib74","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1111\/jth.14690","volume":"18","author":"Moore","year":"2020","journal-title":"J\u00a0Thromb Haemost"}],"container-title":["Journal of Thrombosis and Haemostasis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538783622076486?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538783622076486?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T03:38:16Z","timestamp":1761536296000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1538783622076486"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":74,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["S1538783622076486"],"URL":"https:\/\/doi.org\/10.1016\/j.jtha.2022.11.032","relation":{},"ISSN":["1538-7836"],"issn-type":[{"value":"1538-7836","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Communication from the Scientific Standardization Committees of the International Society on Thrombosis and Haemostasis on vascular endothelium-related biomarkers in disseminated intravascular coagulation","name":"articletitle","label":"Article Title"},{"value":"Journal of Thrombosis and Haemostasis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtha.2022.11.032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 International Society on Thrombosis and Haemostasis. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}