{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T07:42:55Z","timestamp":1792827775464,"version":"4.5.0"},"reference-count":65,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001711","name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","doi-asserted-by":"publisher","award":["320030-197392"],"award-info":[{"award-number":["320030-197392"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004362","name":"Schweizerische Herzstiftung","doi-asserted-by":"publisher","award":["FF19117"],"award-info":[{"award-number":["FF19117"]}],"id":[{"id":"10.13039\/501100004362","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004784","name":"Novartis Stiftung\u00a0f\u00fcr\u00a0Medizinisch-Biologische Forschung","doi-asserted-by":"publisher","award":["18B074"],"award-info":[{"award-number":["18B074"]}],"id":[{"id":"10.13039\/501100004784","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013849","name":"Fondation Dr Henri Dubois-Ferri\u00e8re Dinu Lipatti","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013849","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jthjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Thrombosis and Haemostasis"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.jtha.2023.05.001","type":"journal-article","created":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T12:45:18Z","timestamp":1683722718000},"page":"2291-2299","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":51,"title":["Consensus report on markers to distinguish procoagulant platelets from apoptotic platelets: communication from the Scientific and Standardization Committee of the ISTH"],"prefix":"10.1016","volume":"21","author":[{"given":"Emma C.","family":"Josefsson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"Ramstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Thaler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Lordkipanidz\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ejaife O.","family":"Agbani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Alberio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamam","family":"Bakchoul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth A.","family":"Bouchard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Camera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivien","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrice","family":"Cognasse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith M.E.M.","family":"Cosemans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rutvi G.","family":"Dave","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederik","family":"Denorme","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doroth\u00e9e","family":"Faille","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison H.","family":"Goodall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew T.","family":"Harper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Heemskerk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shawn M.","family":"Jobe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lacey","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andaleb","family":"Kholmukhamedov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saptarshi","family":"Mandal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meganathan","family":"Kannan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Mezzano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Mutch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret L.","family":"Rand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yana","family":"Roka-Moiia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Tersteeg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly A.","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dina","family":"Vara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuping","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtha.2023.05.001_bib1","doi-asserted-by":"crossref","first-page":"2171","DOI":"10.1182\/blood-2017-05-787259","article-title":"Procoagulant platelets: generation, function, and therapeutic targeting in thrombosis","volume":"130","author":"Agbani","year":"2017","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2023.05.001_bib2","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/jth.12045","article-title":"Platelet-based coagulation: different populations, different functions","volume":"11","author":"Heemskerk","year":"2013","journal-title":"J\u00a0Thromb Haemost"},{"key":"10.1016\/j.jtha.2023.05.001_bib3","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1161\/ATVBAHA.113.301790","article-title":"Superactivated platelets: thrombus regulators, thrombin generators, and potential clinical targets","volume":"33","author":"Mazepa","year":"2013","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jtha.2023.05.001_bib4","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3389\/fcvm.2020.00015","article-title":"Procoagulant phosphatidylserine-exposing platelets in\u00a0vitro and in\u00a0vivo","volume":"7","author":"Reddy","year":"2020","journal-title":"Front Cardiovasc Med"},{"key":"10.1016\/j.jtha.2023.05.001_bib5","article-title":"Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines","volume":"7","author":"Th\u00e9ry","year":"2018","journal-title":"J\u00a0Extracell Vesicles"},{"key":"10.1016\/j.jtha.2023.05.001_bib6","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/j.1747-4949.2008.00223.x","article-title":"Coated-platelets in ischemic stroke\u2014potential insight into the etiology of stroke subtypes","volume":"3","author":"Prodan","year":"2008","journal-title":"Int J Stroke"},{"key":"10.1016\/j.jtha.2023.05.001_bib7","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.trsl.2011.02.010","article-title":"Coated-platelet levels are elevated\u00a0in patients with transient ischemic attack","volume":"158","author":"Prodan","year":"2011","journal-title":"Transl Res"},{"key":"10.1016\/j.jtha.2023.05.001_bib8","doi-asserted-by":"crossref","first-page":"30697","DOI":"10.1074\/jbc.M403559200","article-title":"Platelet factor XIII and calpain negatively regulate integrin \u03b1IIb\u03b23 adhesive function and thrombus growth","volume":"279","author":"Kulkarni","year":"2004","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jtha.2023.05.001_bib9","doi-asserted-by":"crossref","first-page":"2615","DOI":"10.1182\/blood.V90.7.2615","article-title":"Collagen but not fibrinogen surfaces induce bleb formation, exposure of phosphatidylserine, and procoagulant activity of adherent platelets: evidence for regulation by protein tyrosine kinase-dependent Ca2+ responses","volume":"90","author":"Heemskerk","year":"1997","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2023.05.001_bib10","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1161\/CIRCULATIONAHA.114.015036","article-title":"Coordinated membrane ballooning and procoagulant spreading in human platelets","volume":"132","author":"Agbani","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.jtha.2023.05.001_bib11","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1111\/j.1538-7836.2005.01274.x","article-title":"Coated-platelets: an emerging component of the procoagulant response","volume":"3","author":"Dale","year":"2005","journal-title":"J\u00a0Thromb Haemost"},{"key":"10.1016\/j.jtha.2023.05.001_bib12","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1182\/blood-2007-05-092684","article-title":"Critical role for the mitochondrial permeability transition pore and cyclophilin D in platelet activation and thrombosis","volume":"111","author":"Jobe","year":"2008","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2023.05.001_bib13","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1160\/TH12-11-0853","article-title":"Contact- and agonist-regulated microvesiculation of human platelets","volume":"110","author":"Zhang","year":"2013","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jtha.2023.05.001_bib14","doi-asserted-by":"crossref","first-page":"29621","DOI":"10.1074\/jbc.M113.474163","article-title":"Procoagulant platelets form an \u03b1-granule protein-covered \u201ccap\u201d on their surface that promotes their attachment to aggregates","volume":"288","author":"Abaeva","year":"2013","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jtha.2023.05.001_bib15","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1182\/blood-2016-02-696898","article-title":"Coagulation factors bound to procoagulant platelets concentrate in cap structures to promote clotting","volume":"128","author":"Podoplelova","year":"2016","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2023.05.001_bib16","doi-asserted-by":"crossref","first-page":"2852","DOI":"10.1182\/blood-2015-08-663005","article-title":"Necrotic platelets provide a procoagulant surface during thrombosis","volume":"126","author":"Hua","year":"2015","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2023.05.001_bib17","doi-asserted-by":"crossref","first-page":"2011","DOI":"10.1182\/blood-2010-01-261669","article-title":"Procoagulant platelets: are they necrotic?","volume":"116","author":"Jackson","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2023.05.001_bib18","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aam5861","article-title":"Neutrophil macroaggregates promote widespread pulmonary thrombosis after gut ischemia","volume":"9","author":"Yuan","year":"2017","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.jtha.2023.05.001_bib19","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1182\/blood.V95.5.1694.005k24_1694_1702","article-title":"Surface expression and functional characterization of alpha-granule factor V in human platelets: effects of ionophore A23187, thrombin, collagen, and convulxin","volume":"95","author":"Alberio","year":"2000","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2023.05.001_bib20","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/0049-3848(96)00028-X","article-title":"Variability in platelet procoagulant activity in healthy volunteers","volume":"81","author":"Sumner","year":"1996","journal-title":"Thromb Res"},{"key":"10.1016\/j.jtha.2023.05.001_bib21","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1038\/nature09583","article-title":"Calcium-dependent phospholipid scrambling by TMEM16F","volume":"468","author":"Suzuki","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.jtha.2023.05.001_bib22","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1111\/bjh.14439","article-title":"A\u00a0new mutation of ANO6 in two familial cases of Scott syndrome","volume":"180","author":"Boisseau","year":"2018","journal-title":"Br J Haematol"},{"key":"10.1016\/j.jtha.2023.05.001_bib23","doi-asserted-by":"crossref","first-page":"4399","DOI":"10.1182\/blood-2011-01-332502","article-title":"Compound heterozygosity for 2 novel TMEM16F mutations in a patient with Scott syndrome","volume":"117","author":"Castoldi","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2023.05.001_bib24","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.bbalip.2003.07.003","article-title":"Scott syndrome, a bleeding disorder caused by defective scrambling of membrane phospholipids","volume":"1636","author":"Zwaal","year":"2004","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.jtha.2023.05.001_bib25","doi-asserted-by":"crossref","first-page":"2152","DOI":"10.1161\/ATVBAHA.116.307727","article-title":"TMEM16F-mediated platelet membrane phospholipid scrambling is critical for hemostasis and thrombosis but not thromboinflammation in mice\u2014brief report","volume":"36","author":"Baig","year":"2016","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jtha.2023.05.001_bib26","doi-asserted-by":"crossref","first-page":"12800","DOI":"10.1073\/pnas.1516594112","article-title":"TMEM16F is required for phosphatidylserine exposure and microparticle release in activated mouse platelets","volume":"112","author":"Fujii","year":"2015","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jtha.2023.05.001_bib27","doi-asserted-by":"crossref","first-page":"13325","DOI":"10.1074\/jbc.M112.428359","article-title":"Dual mechanism of integrin \u03b1IIb\u03b23 closure in procoagulant platelets","volume":"288","author":"Mattheij","year":"2013","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jtha.2023.05.001_bib28","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.cell.2012.07.036","article-title":"TMEM16F forms a Ca2+-activated cation channel required for lipid scrambling in platelets during blood coagulation","volume":"151","author":"Yang","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.jtha.2023.05.001_bib29","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1182\/blood-2009-01-200345","article-title":"Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function","volume":"114","author":"Schoenwaelder","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2023.05.001_bib30","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1080\/09537104.2021.1881951","article-title":"Cytosolic and mitochondrial Ca2+ signaling in procoagulant platelets","volume":"32","author":"Millington-Burgess","year":"2021","journal-title":"Platelets"},{"key":"10.1016\/j.jtha.2023.05.001_bib31","doi-asserted-by":"crossref","first-page":"2536","DOI":"10.3390\/ijms23052536","article-title":"Mechanisms underlying dichotomous procoagulant COAT platelet generation\u2014a conceptual review summarizing current knowledge","volume":"23","author":"Veuthey","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jtha.2023.05.001_bib32","doi-asserted-by":"crossref","first-page":"497","DOI":"10.3109\/09537104.2016.1161739","article-title":"Regulation of platelet lifespan by apoptosis","volume":"27","author":"Lebois","year":"2016","journal-title":"Platelets"},{"key":"10.1016\/j.jtha.2023.05.001_bib33","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1016\/j.cell.2007.01.037","article-title":"Programmed anuclear cell death delimits platelet life span","volume":"128","author":"Mason","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.jtha.2023.05.001_bib34","doi-asserted-by":"crossref","first-page":"1850","DOI":"10.1182\/blood-2012-09-454314","article-title":"Both TMEM16F-dependent and TMEM16F-independent pathways contribute to phosphatidylserine exposure in platelet apoptosis and platelet activation","volume":"121","author":"van Kruchten","year":"2013","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2023.05.001_bib35","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1038\/sj.cdd.4402081","article-title":"Bcl-2 family proteins are essential for platelet survival","volume":"14","author":"Zhang","year":"2007","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.jtha.2023.05.001_bib36","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1182\/blood-2017-11-816355","article-title":"Intrinsic apoptosis circumvents the functional decline of circulating platelets but does not cause the storage lesion","volume":"132","author":"Pleines","year":"2018","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2023.05.001_bib37","doi-asserted-by":"crossref","first-page":"11107","DOI":"10.1016\/S0021-9258(17)39154-8","article-title":"Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation","volume":"260","author":"Shattil","year":"1985","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jtha.2023.05.001_bib38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-017-19126-8","article-title":"Platelet subpopulations remain despite strong dual agonist stimulation and can be characterised using a novel six-colour flow cytometry protocol","volume":"8","author":"S\u00f6dergren","year":"2018","journal-title":"Sci Rep"},{"key":"10.1016\/j.jtha.2023.05.001_bib39","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1161\/ATVBAHA.120.315583","article-title":"Platelet dysfunction during mechanical circulatory support: elevated shear stress promotes downregulation of \u03b1IIb\u03b23 and GPIb via microparticle shedding decreasing platelet aggregability","volume":"41","author":"Roka-Moiia","year":"2021","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jtha.2023.05.001_bib40","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1161\/ATVBAHA.117.309473","article-title":"Inner mitochondrial membrane disruption links apoptotic and agonist-initiated phosphatidylserine externalization in platelets","volume":"37","author":"Choo","year":"2017","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jtha.2023.05.001_bib41","doi-asserted-by":"crossref","first-page":"2475","DOI":"10.1161\/ATVBAHA.112.253765","article-title":"Two types of procoagulant platelets are formed upon physiological activation and are controlled by integrin \u03b1IIb\u03b23","volume":"32","author":"Topalov","year":"2012","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jtha.2023.05.001_bib42","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/cyto.a.22567","article-title":"Formaldehyde-fixation of platelets for flow cytometric measurement of phosphatidylserine exposure is feasible","volume":"87","author":"Rochat","year":"2015","journal-title":"Cytometry A"},{"key":"10.1016\/j.jtha.2023.05.001_bib43","doi-asserted-by":"crossref","first-page":"2535","DOI":"10.1182\/blood-2018-03-742668","article-title":"Mechanisms of receptor shedding in platelets","volume":"132","author":"Montague","year":"2018","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2023.05.001_bib44","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1182\/blood-2011-04-347849","article-title":"Bcl-xL\u2013inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets","volume":"118","author":"Schoenwaelder","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2023.05.001_bib45","doi-asserted-by":"crossref","first-page":"6200","DOI":"10.1021\/bi992221r","article-title":"Functional analyses of two cellular binding domains of bovine lactadherin","volume":"39","author":"Andersen","year":"2000","journal-title":"Biochemistry"},{"key":"10.1016\/j.jtha.2023.05.001_bib46","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1089\/dna.1997.16.861","article-title":"Lactadherin (formerly BA46), a membrane-associated glycoprotein expressed in human milk and breast carcinomas, promotes Arg\u2013Gly\u2013Asp (RGD)-dependent cell adhesion","volume":"16","author":"Taylor","year":"1997","journal-title":"DNA Cell Biol"},{"key":"10.1016\/j.jtha.2023.05.001_bib47","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1097\/00001721-199402000-00014","article-title":"Platelet activation by thrombin can be directly measured in whole blood through the use of the peptide GPRP and flow cytometry: methods and clinical applications","volume":"5","author":"Michelson","year":"1994","journal-title":"Blood Coagul Fibrinolysis"},{"key":"10.1016\/j.jtha.2023.05.001_bib48","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1160\/TH16-09-0711","article-title":"Delayed-onset of procoagulant signalling revealed by kinetic analysis of COAT platelet formation","volume":"117","author":"Alberio","year":"2017","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jtha.2023.05.001_bib49","doi-asserted-by":"crossref","first-page":"7145","DOI":"10.1182\/blood-2011-03-344812","article-title":"BCL2\/BCL-XL inhibition induces apoptosis, disrupts cellular calcium homeostasis, and prevents platelet activation","volume":"117","author":"Vogler","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2023.05.001_bib50","doi-asserted-by":"crossref","first-page":"4283","DOI":"10.1182\/blood-2011-11-394858","article-title":"Caspase-9 mediates the apoptotic death of megakaryocytes and platelets, but is dispensable for their generation and function","volume":"119","author":"White","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2023.05.001_bib51","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/978-1-61779-307-3_5","article-title":"Platelet life span and apoptosis","volume":"788","author":"Josefsson","year":"2012","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.jtha.2023.05.001_bib52","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1055\/s-0040-1709524","article-title":"Platelet activation via shear stress exposure induces a differing pattern of biomarkers of activation versus biochemical agonists","volume":"120","author":"Roka-Moiia","year":"2020","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jtha.2023.05.001_bib53","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1002\/cyto.10114","article-title":"Flow cytometric detection of activated mouse integrin alphaIIbbeta3 with a novel monoclonal antibody","volume":"48","author":"Bergmeier","year":"2002","journal-title":"Cytometry"},{"key":"10.1016\/j.jtha.2023.05.001_bib54","doi-asserted-by":"crossref","first-page":"30672","DOI":"10.1074\/jbc.M113.472688","article-title":"Mitochondrially mediated integrin \u03b1IIb\u03b23 protein inactivation limits thrombus growth","volume":"288","author":"Liu","year":"2013","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jtha.2023.05.001_bib55","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1038\/415175a","article-title":"Stimulated platelets use serotonin to enhance their retention of procoagulant proteins on the cell surface","volume":"415","author":"Dale","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.jtha.2023.05.001_bib56","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1055\/s-0040-171670","article-title":"Sodium-calcium exchanger reverse mode sustains dichotomous ion fluxes required for procoagulant COAT platelet formation","volume":"121","author":"Aliotta","year":"2021","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jtha.2023.05.001_bib57","doi-asserted-by":"crossref","first-page":"4337","DOI":"10.1182\/blood-2012-02-413070","article-title":"Bcl-xL-inhibitory BH3 mimetic ABT-737 depletes platelet calcium stores","volume":"119","author":"Harper","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2023.05.001_bib58","doi-asserted-by":"crossref","first-page":"427","DOI":"10.3324\/haematol.2015.131441","article-title":"Coated platelets function in platelet-dependent fibrin formation via integrin \u03b1IIb\u03b23 and transglutaminase factor XIII","volume":"101","author":"Mattheij","year":"2016","journal-title":"Haematologica"},{"key":"10.1016\/j.jtha.2023.05.001_bib59","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/978-1-4939-9187-7_20","article-title":"Flow cytometry assessment of procoagulant platelets using a dithiol-reactive probe","volume":"1967","author":"Tan","year":"2019","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.jtha.2023.05.001_bib60","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/ijlh.13197","article-title":"Procoagulant platelets: laboratory detection and clinical significance","volume":"42","author":"Tohidi-Esfahani","year":"2020","journal-title":"Int J Lab Hematol"},{"key":"10.1016\/j.jtha.2023.05.001_bib61","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1160\/TH14-10-0830","article-title":"Human megakaryocytes confer tissue factor to a subset of shed platelets to stimulate thrombin generation","volume":"114","author":"Brambilla","year":"2015","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jtha.2023.05.001_bib62","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/cei.13248","article-title":"Tissue factor over-expression in platelets of patients with anti-phospholipid syndrome: induction role of anti-\u03b22-GPI antibodies","volume":"196","author":"Capozzi","year":"2019","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.jtha.2023.05.001_bib63","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.atherosclerosis.2016.12.019","article-title":"Platelet tissue factor activity and membrane cholesterol are increased in hypercholesterolemia and normalized by rosuvastatin, but not by atorvastatin","volume":"257","author":"Panes","year":"2017","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jtha.2023.05.001_bib64","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.thromres.2013.05.009","article-title":"Platelet tissue factor: to be or not to be","volume":"132","author":"Mackman","year":"2013","journal-title":"Thromb Res"},{"key":"10.1016\/j.jtha.2023.05.001_bib65","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1080\/09537104.2019.1624708","article-title":"Detection of tissue factor in platelets: why is it so troublesome?","volume":"30","author":"\u00d8sterud","year":"2019","journal-title":"Platelets"}],"container-title":["Journal of Thrombosis and Haemostasis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S153878362300394X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S153878362300394X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T03:39:36Z","timestamp":1761536376000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S153878362300394X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":65,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["S153878362300394X"],"URL":"https:\/\/doi.org\/10.1016\/j.jtha.2023.05.001","relation":{},"ISSN":["1538-7836"],"issn-type":[{"value":"1538-7836","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Consensus report on markers to distinguish procoagulant platelets from apoptotic platelets: communication from the Scientific and Standardization Committee of the ISTH","name":"articletitle","label":"Article Title"},{"value":"Journal of Thrombosis and Haemostasis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtha.2023.05.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 International Society on Thrombosis and Haemostasis. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}