{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T08:07:21Z","timestamp":1792829241484,"version":"4.5.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100015438","name":"ISTH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015438","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jthjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Thrombosis and Haemostasis"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.jtha.2023.05.027","type":"journal-article","created":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T12:13:41Z","timestamp":1686917621000},"page":"2596-2610","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["Multicenter evaluation of light transmission platelet aggregation reagents: communication from the ISTH SSC Subcommittee on Platelet Physiology"],"prefix":"10.1016","volume":"21","author":[{"given":"Marie-Christine","family":"Alessi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Coxon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manal","family":"Ibrahim-Kosta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Bacci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Voisin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Rivera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Greinacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Raster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Pulcinelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrien M.J.","family":"Devreese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francois","family":"Mullier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aine N.","family":"McCormick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Pablo","family":"Frontroth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Pouplard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich J.","family":"Sachs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Diaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuria","family":"Bermejo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Camera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Fontana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Bauters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Stepanian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria R.","family":"Cozzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastasia N.","family":"Sveshnikova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doroth\u00e9e","family":"Faille","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy","family":"Hollon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meera","family":"Chitlur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Casonato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Lasne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"Lavenu-Bombled","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Fiore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bello","family":"Hamidou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Francoise","family":"Hurtaud-Roux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Saultier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louisa","family":"Goumidi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Gresele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Lordkipanidz\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtha.2023.05.027_bib1","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1038\/194927b0","article-title":"Aggregation of blood platelets by adenosine diphosphate and its reversal","volume":"194","author":"Born","year":"1962","journal-title":"Nature"},{"key":"10.1016\/j.jtha.2023.05.027_bib2","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1136\/jcp.15.5.446","article-title":"Platelet aggregation: part I some effects of the adenosine phosphates, thrombin, and cocaine upon platelet adhesiveness","volume":"15","author":"O\u2019Brien","year":"1962","journal-title":"J\u00a0Clin Pathol"},{"key":"10.1016\/j.jtha.2023.05.027_bib3","first-page":"86","article-title":"Macroscopic studies of platelet aggregation. Nature of an aggregating factor in red blood cells and platelets","volume":"6","author":"Ollgaard","year":"1961","journal-title":"Thromb Diath Haemorrh"},{"key":"10.1016\/j.jtha.2023.05.027_bib4","first-page":"763","article-title":"Strengths and weaknesses of light transmission aggregometry in diagnosing hereditary platelet function disorders","volume":"9","author":"Alessi","year":"2020","journal-title":"J\u00a0Clin Med"},{"key":"10.1016\/j.jtha.2023.05.027_bib5","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1111\/jth.12231","article-title":"Recommendations for the standardization of light transmission aggregometry: a consensus of the working party from the platelet physiology subcommittee of SSC\/ISTH","volume":"11","author":"Cattaneo","year":"2013","journal-title":"J\u00a0Thromb Haemost"},{"key":"10.1016\/j.jtha.2023.05.027_bib6","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1111\/jth.12792","article-title":"Subcommittee on Platelet Physiology of the International Society on Thrombosis and Hemostasis. Diagnosis of inherited platelet function disorders: guidance from the SSC of the ISTH","volume":"13","author":"Gresele","year":"2015","journal-title":"J\u00a0Thromb Haemost"},{"key":"10.1016\/j.jtha.2023.05.027_bib7","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1111\/jth.13022","article-title":"Circulating primers enhance platelet function and induce resistance to antiplatelet therapy","volume":"13","author":"Blair","year":"2015","journal-title":"J\u00a0Thromb Haemost"},{"key":"10.1016\/j.jtha.2023.05.027_bib8","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1111\/j.1538-7836.2009.03273.x","article-title":"Diagnostic utility of light transmission platelet aggregometry: results from a prospective study of individuals referred for bleeding disorder assessments","volume":"7","author":"Hayward","year":"2009","journal-title":"J\u00a0Thromb Haemost"},{"issue":"Suppl 1","key":"10.1016\/j.jtha.2023.05.027_bib9","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/ijlh.12814","article-title":"Laboratory diagnosis of clinically relevant platelet function disorders","volume":"40","author":"Gresele","year":"2018","journal-title":"Int J Lab Hematol"},{"key":"10.1016\/j.jtha.2023.05.027_bib10","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.thromres.2009.04.003","article-title":"Insights into the interpretation of light transmission aggregometry for evaluation of platelet aggregation inhibition by clopidogrel","volume":"124","author":"Lordkipanidz\u00e9","year":"2009","journal-title":"Thromb Res"},{"issue":"Suppl 1","key":"10.1016\/j.jtha.2023.05.027_bib11","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/ijlh.12995","article-title":"Update on diagnostic testing for platelet function disorders: what is practical and useful?","volume":"41","author":"Hayward","year":"2019","journal-title":"Int J Lab Hematol"},{"key":"10.1016\/j.jtha.2023.05.027_bib12","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1309\/AJCP9V3RRVNZMKDS","article-title":"Development of North American consensus guidelines for medical laboratories that perform and interpret platelet function testing using light transmission aggregometry","volume":"134","author":"Hayward","year":"2010","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.jtha.2023.05.027_bib13","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1080\/09537104.2020.1771549","article-title":"Harmonizing light transmission aggregometry in the Netherlands by implementation of the SSC-ISTH guideline","volume":"32","author":"Munnix","year":"2021","journal-title":"Platelets"},{"key":"10.1016\/j.jtha.2023.05.027_bib14","doi-asserted-by":"crossref","first-page":"4017","DOI":"10.1182\/bloodadvances.2020003261","article-title":"Multiparameter phenotyping of platelet reactivity for stratification of human cohorts","volume":"5","author":"Dunster","year":"2021","journal-title":"Blood Adv"},{"key":"10.1016\/j.jtha.2023.05.027_bib15","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1055\/s-0039-1688791","article-title":"Standardisation of light transmission aggregometry for diagnosis of platelet disorders: an inter-laboratory external quality assessment","volume":"119","author":"Althaus","year":"2019","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jtha.2023.05.027_bib16","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1002\/rth2.12140","article-title":"A\u00a0multicenter study to evaluate automated platelet aggregometry on Sysmex CS-series coagulation analyzers-preliminary findings","volume":"2","author":"Platton","year":"2018","journal-title":"Res Pract Thromb Haemost"},{"key":"10.1016\/j.jtha.2023.05.027_bib17","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1111\/j.1365-2141.2009.07890.x","article-title":"Diagnosis of mild platelet function disorders. Reliability and usefulness of light transmission platelet aggregation and serotonin secretion assays","volume":"147","author":"Quiroga","year":"2009","journal-title":"Br J Haematol"},{"key":"10.1016\/j.jtha.2023.05.027_bib18","doi-asserted-by":"crossref","first-page":"e56","DOI":"10.1055\/s-0043-1762588","article-title":"Automated light transmission aggregometry with and without platelet poor plasma reference: a method comparison","volume":"7","author":"Sachs","year":"2023","journal-title":"TH Open"},{"key":"10.1016\/j.jtha.2023.05.027_bib19","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/BF00541530","article-title":"Simultaneous measurement of epinephrine-induced platelet aggregation in 14 plasma samples","volume":"30","author":"Nelson","year":"1986","journal-title":"Eur J Clin Pharmacol"},{"key":"10.1016\/j.jtha.2023.05.027_bib20","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1111\/bjh.17690","article-title":"British Society for Haematology Guidelines, British Society for Haematology Guidelines. Clinical and laboratory diagnosis of heritable platelet disorders in adults and children: a British Society for Haematology Guideline","volume":"195","author":"Gomez","year":"2021","journal-title":"Br J Haematol"},{"key":"10.1016\/j.jtha.2023.05.027_bib21","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/0895-7061(95)00155-I","article-title":"Genetic polymorphism of the alpha 2-adrenergic receptor is associated with increased platelet aggregation, baroreceptor sensitivity, and salt excretion in normotensive humans","volume":"8","author":"Freeman","year":"1995","journal-title":"Am J Hypertens"},{"key":"10.1016\/j.jtha.2023.05.027_bib22","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1038\/ng.604","article-title":"Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists","volume":"42","author":"Johnson","year":"2010","journal-title":"Nat Genet"},{"key":"10.1016\/j.jtha.2023.05.027_bib23","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1111\/ijlh.13579","article-title":"Devreese KMJ Is monitoring of antiplatelet therapy by light transmission aggregometry dependent on instrument and reagent used?","volume":"43","author":"Monteyne","year":"2021","journal-title":"Int J Lab Hematol"},{"key":"10.1016\/j.jtha.2023.05.027_bib24","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1111\/j.1751-553X.2008.01051.x","article-title":"Methodology and outcomes of platelet aggregation testing in Australia, New Zealand and the Asia-Pacific region: results of a survey from the Royal College of Pathologists of Australasia Haematology Quality Assurance Program","volume":"31","author":"Duncan","year":"2009","journal-title":"Int J Lab Hematol"},{"key":"10.1016\/j.jtha.2023.05.027_bib25","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3000338","article-title":"Applying the science of measurement to biology: why bother?","volume":"17","author":"Coxon","year":"2019","journal-title":"PLOS Biol"}],"container-title":["Journal of Thrombosis and Haemostasis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538783623004920?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538783623004920?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T03:40:41Z","timestamp":1761536441000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1538783623004920"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":25,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["S1538783623004920"],"URL":"https:\/\/doi.org\/10.1016\/j.jtha.2023.05.027","relation":{},"ISSN":["1538-7836"],"issn-type":[{"value":"1538-7836","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multicenter evaluation of light transmission platelet aggregation reagents: communication from the ISTH SSC Subcommittee on Platelet Physiology","name":"articletitle","label":"Article Title"},{"value":"Journal of Thrombosis and Haemostasis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtha.2023.05.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 International Society on Thrombosis and Haemostasis. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}