{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T08:44:06Z","timestamp":1767602646369,"version":"3.48.0"},"reference-count":16,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["jthjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Thrombosis and Haemostasis"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.jtha.2025.09.016","type":"journal-article","created":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T23:51:39Z","timestamp":1760140299000},"page":"298-302","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Adding contrast to shed some light\u2014a case of acute thrombocytopenia due to iohexol-dependent antibodies to glycoprotein IIb\/IIIa"],"prefix":"10.1016","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6379-4018","authenticated-orcid":false,"given":"Ingvild Jenssen","family":"L\u00e6greid","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-1459-7500","authenticated-orcid":false,"given":"Erin Mathiesen","family":"Hald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirjana Grujic","family":"Arsenovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9515-0922","authenticated-orcid":false,"given":"Siw Leiknes","family":"Ernstsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3696-355X","authenticated-orcid":false,"given":"Klara","family":"Asplund H\u00f6gelin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0808-0183","authenticated-orcid":false,"given":"Trude Victoria","family":"M\u00f8rtberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3104-3818","authenticated-orcid":false,"given":"Maria Therese","family":"Ahlen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtha.2025.09.016_bib1","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1007\/s13730-020-00468-8","article-title":"Contrast medium-induced severe thrombocytopenia in patient on maintenance hemodialysis: a case report and literature review","volume":"9","author":"Takeda","year":"2020","journal-title":"CEN Case Rep"},{"key":"10.1016\/j.jtha.2025.09.016_bib2","article-title":"Thrombocytopenia induced by iodinated contrast media: a systematic review","volume":"10","author":"Guerrero-M\u00e1rquez","year":"2022","journal-title":"Med Res Arch"},{"key":"10.1016\/j.jtha.2025.09.016_bib3","doi-asserted-by":"crossref","first-page":"947","DOI":"10.2214\/ajr.152.5.947","article-title":"Acute thrombocytopenia after i.v. administration of a radiographic contrast medium","volume":"152","author":"Chang","year":"1989","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.jtha.2025.09.016_bib4","first-page":"885","article-title":"Acute thrombocytopenia after intravenous infusion of radiographic contrast medium","volume":"33","author":"Kudoh","year":"1991","journal-title":"Nihon Jinzo Gakkai Shi"},{"key":"10.1016\/j.jtha.2025.09.016_bib5","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1055\/s-2008-1055470","article-title":"Rezidivierende Immunthrombozytopenie. Seltene Komplikation nach Kontrastmittelexposition [Recurrent immune thrombocytopenia: a rare complication after contrast medium injection]","volume":"120","author":"Wiemer","year":"1995","journal-title":"Dtsch Med Wochenschr"},{"key":"10.1016\/j.jtha.2025.09.016_bib6","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1007\/s002280050516","article-title":"Thrombocytopenia following intravenous iopamidol","volume":"54","author":"Ural","year":"1998","journal-title":"Eur J Clin Pharmacol"},{"key":"10.1016\/j.jtha.2025.09.016_bib7","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1111\/jth.12852","article-title":"Platelet Immunology Scientific Subcommittee of the International Society on Thrombosis and Hemostasis. Recommendations for standardization of laboratory testing for drug-induced immune thrombocytopenia: communication from the SSC of the ISTH","volume":"13","author":"Arnold","year":"2015","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.jtha.2025.09.016_bib8","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1111\/trf.16858","article-title":"Acute drug-induced immune thrombocytopenia - A work of articaine","volume":"62","author":"Laegreid","year":"2022","journal-title":"Transfusion"},{"key":"10.1016\/j.jtha.2025.09.016_bib9","doi-asserted-by":"crossref","first-page":"886","DOI":"10.7326\/0003-4819-129-11_Part_1-199812010-00009","article-title":"Drug-induced thrombocytopenia: a systematic review of published case reports","volume":"129","author":"George","year":"1998","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jtha.2025.09.016_bib11","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.mayocp.2012.01.012","article-title":"Clinical pharmacology, uses, and adverse reactions of iodinated contrast agents: a primer for the non-radiologist","volume":"87","author":"Pasternak","year":"2012","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.jtha.2025.09.016_bib12","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1097\/MS9.0000000000000150","article-title":"Acute severe thrombocytopenia following iodinated radiographic contrast medium infusion: a case report","volume":"85","author":"Sharawi","year":"2023","journal-title":"Ann Med Surg (Lond)"},{"key":"10.1016\/j.jtha.2025.09.016_bib13","first-page":"111","article-title":"Biochemical-pharmacologic properties of iohexol","volume":"362","author":"M\u00fctzel","year":"1980","journal-title":"Acta Radiol Suppl"},{"key":"10.1016\/j.jtha.2025.09.016_bib14","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1053\/j.ajkd.2015.08.020","article-title":"Discordance between iothalamate and iohexol urinary clearances","volume":"67","author":"Seegmiller","year":"2016","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.jtha.2025.09.016_bib15","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.molliq.2017.10.096","article-title":"Multispectral and molecular docking studies on the interaction of human serum albumin with iohexol","volume":"248","author":"Hasanzadeh","year":"2017","journal-title":"J Mol Liquids"},{"key":"10.1016\/j.jtha.2025.09.016_bib16","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0014-5793(94)01356-6","article-title":"Angiography contrast agents interact with serine proteinases. The molecular structure of the model system elastase\/iohexol","volume":"357","author":"Prang\u00e9","year":"1995","journal-title":"FEBS Lett"},{"key":"10.1016\/j.jtha.2025.09.016_bib17","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1093\/ckj\/sfw070","article-title":"Iohexol plasma clearance for measuring glomerular filtration rate in clinical practice and research: a review. Part 1: How to measure glomerular filtration rate with iohexol?","volume":"9","author":"Delanaye","year":"2016","journal-title":"Clin Kidney J"}],"container-title":["Journal of Thrombosis and Haemostasis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538783625006075?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538783625006075?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T08:40:10Z","timestamp":1767602410000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1538783625006075"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["S1538783625006075"],"URL":"https:\/\/doi.org\/10.1016\/j.jtha.2025.09.016","relation":{},"ISSN":["1538-7836"],"issn-type":[{"type":"print","value":"1538-7836"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adding contrast to shed some light\u2014a case of acute thrombocytopenia due to iohexol-dependent antibodies to glycoprotein IIb\/IIIa","name":"articletitle","label":"Article Title"},{"value":"Journal of Thrombosis and Haemostasis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtha.2025.09.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 International Society on Thrombosis and Haemostasis. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}