{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T08:12:01Z","timestamp":1778227921185,"version":"3.51.4"},"reference-count":53,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T00:00:00Z","timestamp":1770336000000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009023","name":"Precursory Research for Embryonic Science and Technology","doi-asserted-by":"publisher","award":["JPMJPR19G9"],"award-info":[{"award-number":["JPMJPR19G9"]}],"id":[{"id":"10.13039\/501100009023","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007449","name":"Takeda Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007449","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP22K16486"],"award-info":[{"award-number":["JP22K16486"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP21H03352"],"award-info":[{"award-number":["JP21H03352"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP25K14809"],"award-info":[{"award-number":["JP25K14809"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP25K02569"],"award-info":[{"award-number":["JP25K02569"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP24K02857"],"award-info":[{"award-number":["JP24K02857"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP22K08153"],"award-info":[{"award-number":["JP22K08153"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004713","name":"Hospital Universiti Sains Malaysia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004713","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jthjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Thrombosis and Haemostasis"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.jtha.2025.09.027","type":"journal-article","created":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T16:14:48Z","timestamp":1760804088000},"page":"583-597","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Microthrombi growth in ADAMTS13 deficiency exacerbates inflammatory bowel disease via mucosal and endothelial dysfunction"],"prefix":"10.1016","volume":"24","author":[{"given":"Kyota","family":"Tatsuta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6018-867X","authenticated-orcid":false,"given":"Naoki","family":"Honkura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nanami","family":"Morooka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayu","family":"Sakata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyotaka","family":"Kurachi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Sugimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichi","family":"Kokame","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroya","family":"Takeuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsumei","family":"Urano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4833-8580","authenticated-orcid":false,"given":"Yuko","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtha.2025.09.027_bib1","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1016\/S0140-6736(16)32126-2","article-title":"Ulcerative colitis","volume":"389","author":"Ungaro","year":"2017","journal-title":"Lancet"},{"key":"10.1016\/j.jtha.2025.09.027_bib2","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.1136\/gutjnl-2018-317571","article-title":"Structural weakening of the colonic mucus barrier is an early event in ulcerative colitis pathogenesis","volume":"68","author":"van der Post","year":"2019","journal-title":"Gut"},{"key":"10.1016\/j.jtha.2025.09.027_bib3","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/nri3661","article-title":"Cytokines in inflammatory bowel disease","volume":"14","author":"Neurath","year":"2014","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.jtha.2025.09.027_bib4","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/S0140-6736(23)00966-2","article-title":"Ulcerative colitis","volume":"402","author":"Le Berre","year":"2023","journal-title":"Lancet"},{"key":"10.1016\/j.jtha.2025.09.027_bib5","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1056\/NEJMoa1606910","article-title":"Tofacitinib as induction and maintenance therapy for ulcerative colitis","volume":"376","author":"Sandborn","year":"2017","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jtha.2025.09.027_bib6","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1056\/NEJMoa1905725","article-title":"Vedolizumab versus adalimumab for moderate-to-severe ulcerative colitis","volume":"381","author":"Sands","year":"2019","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jtha.2025.09.027_bib7","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.2353\/ajpath.2008.070593","article-title":"Multiple pathogenic roles of microvasculature in inflammatory bowel disease: a Jack of all trades","volume":"172","author":"Deban","year":"2008","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jtha.2025.09.027_bib8","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1136\/gut.33.4.502","article-title":"Circulating von Willebrand factor in inflammatory bowel disease","volume":"33","author":"Stevens","year":"1992","journal-title":"Gut"},{"key":"10.1016\/j.jtha.2025.09.027_bib9","doi-asserted-by":"crossref","first-page":"3212","DOI":"10.1182\/blood-2011-02-306597","article-title":"Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor","volume":"118","author":"Crawley","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2025.09.027_bib10","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1182\/blood-2004-01-0107","article-title":"Effects of inflammatory cytokines on the release and cleavage of the endothelial cell-derived ultralarge von Willebrand-factor multimers under flow","volume":"104","author":"Bernardo","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2025.09.027_bib11","doi-asserted-by":"crossref","first-page":"4796","DOI":"10.3748\/wjg.v23.i26.4796","article-title":"Levels and activities of von Willebrand factor and metalloproteinase with thrombospondin type-1 motif, number 13 in inflammatory bowel diseases","volume":"23","author":"Cibor","year":"2017","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.jtha.2025.09.027_bib12","doi-asserted-by":"crossref","first-page":"e11","DOI":"10.1055\/s-0037-1603927","article-title":"ADAMTS13 deficiency worsens colitis and exogenous ADAMTS13 administration decreases colitis severity in mice","volume":"1","author":"Zitomersky","year":"2017","journal-title":"TH Open"},{"key":"10.1016\/j.jtha.2025.09.027_bib13","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1365-2559.1992.tb00360.x","article-title":"Mucosal capillary thrombi in rectal biopsies","volume":"21","author":"Dhillon","year":"1992","journal-title":"Histopathology"},{"key":"10.1016\/j.jtha.2025.09.027_bib14","doi-asserted-by":"crossref","first-page":"2236","DOI":"10.1007\/s10620-006-9158-5","article-title":"The microvacular thrombi of colonic tissue in ulcerative colitis","volume":"52","author":"He","year":"2007","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.jtha.2025.09.027_bib15","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1182\/blood-2008-03-144279","article-title":"Unique secretory dynamics of tissue plasminogen activator and its modulation by plasminogen activator inhibitor-1 in vascular endothelial cells","volume":"113","author":"Suzuki","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2025.09.027_bib16","doi-asserted-by":"crossref","first-page":"3182","DOI":"10.1182\/blood-2011-05-353912","article-title":"Surface-retained tPA is essential for effective fibrinolysis on vascular endothelial cells","volume":"118","author":"Suzuki","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2025.09.027_bib17","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1160\/TH16-09-0722","article-title":"Imaging analyses of coagulation-dependent initiation of fibrinolysis on activated platelets and its modification by thrombin-activatable fibrinolysis inhibitor","volume":"117","author":"Brzoska","year":"2017","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jtha.2025.09.027_bib18","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1038\/nm782","article-title":"Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse","volume":"8","author":"Falati","year":"2002","journal-title":"Nat Med"},{"key":"10.1016\/j.jtha.2025.09.027_bib19","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0122196","article-title":"Endogenously generated plasmin at the vascular wall injury site amplifies lysine binding site-dependent plasminogen accumulation in microthrombi","volume":"10","author":"Brzoska","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.jtha.2025.09.027_bib20","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1007\/s00424-008-0466-9","article-title":"Real-time analysis of platelet aggregation and procoagulant activity during thrombus formation in vivo","volume":"456","author":"Hayashi","year":"2008","journal-title":"Pflugers Arch"},{"key":"10.1016\/j.jtha.2025.09.027_bib21","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1007\/s00424-011-0958-x","article-title":"In vivo imaging analysis of the interaction between unusually large von Willebrand factor multimers and platelets on the surface of vascular wall","volume":"461","author":"Rybaltowski","year":"2011","journal-title":"Pflugers Arch"},{"key":"10.1016\/j.jtha.2025.09.027_bib22","doi-asserted-by":"crossref","first-page":"2746","DOI":"10.1038\/s41467-018-04929-8","article-title":"Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events","volume":"9","author":"Honkura","year":"2018","journal-title":"Nat Commun"},{"key":"10.1016\/j.jtha.2025.09.027_bib23","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/S0014-5793(97)00313-X","article-title":"\u201cGreen mice\u201d as a source of ubiquitous green cells","volume":"407","author":"Okabe","year":"1997","journal-title":"FEBS Lett"},{"key":"10.1016\/j.jtha.2025.09.027_bib24","doi-asserted-by":"crossref","first-page":"3161","DOI":"10.1182\/blood-2005-07-2765","article-title":"Complete deficiency in ADAMTS13 is prothrombotic, but it alone is not sufficient to cause thrombotic thrombocytopenic purpura","volume":"107","author":"Banno","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2025.09.027_bib25","first-page":"3678","article-title":"Investigating intestinal inflammation in DSS-induced model of IBD","volume":"60","author":"Kim","year":"2012","journal-title":"J Vis Exp"},{"key":"10.1016\/j.jtha.2025.09.027_bib26","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1111\/j.1538-7836.2006.01833.x","article-title":"ADAMTS-13 plasma level determination uncovers antigen absence in acquired thrombotic thrombocytopenic purpura and ethnic differences","volume":"4","author":"Feys","year":"2006","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.jtha.2025.09.027_bib27","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1056\/NEJM198712243172603","article-title":"Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study","volume":"317","author":"Schroeder","year":"1987","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jtha.2025.09.027_bib28","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1053\/j.gastro.2015.07.003","article-title":"Biomarkers of inflammation in inflammatory bowel disease","volume":"149","author":"Sands","year":"2015","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jtha.2025.09.027_bib29","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/s41467-018-07841-3","article-title":"Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response","volume":"10","author":"Haberman","year":"2019","journal-title":"Nat Commun"},{"key":"10.1016\/j.jtha.2025.09.027_bib30","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1093\/ibd\/izaa075","article-title":"Transcriptional signatures that define ulcerative colitis in remission","volume":"27","author":"Fenton","year":"2021","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.jtha.2025.09.027_bib31","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/0016-5085(90)90290-H","article-title":"A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice","volume":"98","author":"Okayasu","year":"1990","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jtha.2025.09.027_bib32","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1038\/nprot.2017.044","article-title":"Chemically induced mouse models of acute and chronic intestinal inflammation","volume":"12","author":"Wirtz","year":"2017","journal-title":"Nat Protoc"},{"key":"10.1016\/j.jtha.2025.09.027_bib33","doi-asserted-by":"crossref","first-page":"15064","DOI":"10.1073\/pnas.0803124105","article-title":"The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria","volume":"105","author":"Johansson","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jtha.2025.09.027_bib34","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1136\/gutjnl-2011-301956","article-title":"Ischaemia-induced mucus barrier loss and bacterial penetration are rapidly counteracted by increased goblet cell secretory activity in human and rat colon","volume":"62","author":"Grootjans","year":"2013","journal-title":"Gut"},{"key":"10.1016\/j.jtha.2025.09.027_bib35","doi-asserted-by":"crossref","first-page":"2168","DOI":"10.1182\/blood-2018-11-844555","article-title":"Cross talk between neutrophils and the microbiota","volume":"133","author":"Zhang","year":"2019","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2025.09.027_bib36","doi-asserted-by":"crossref","first-page":"4193","DOI":"10.3748\/wjg.v16.i33.4193","article-title":"Effect of Arctium lappa L. in the dextran sulfate sodium colitis mouse model","volume":"16","author":"Huang","year":"2010","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.jtha.2025.09.027_bib37","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/0026-2862(86)90007-5","article-title":"Hemodynamics at stenoses formed by growing platelet thrombi in mesenteric microvasculature of rat","volume":"31","author":"Sato","year":"1986","journal-title":"Microvasc Res"},{"key":"10.1016\/j.jtha.2025.09.027_bib38","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.67292","article-title":"Intestinal goblet cells sample and deliver lumenal antigens by regulated endocytic uptake and transcytosis","volume":"10","author":"Gustafsson","year":"2021","journal-title":"Elife"},{"key":"10.1016\/j.jtha.2025.09.027_bib39","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1038\/s41385-018-0069-5","article-title":"In vivo imaging reveals unique neutrophil transendothelial migration patterns in inflamed intestines","volume":"11","author":"Sullivan","year":"2018","journal-title":"Mucosal Immunol"},{"key":"10.1016\/j.jtha.2025.09.027_bib40","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0041009","article-title":"Fast renewal of the distal colonic mucus layers by the surface goblet cells as measured by in vivo labeling of mucin glycoproteins","volume":"7","author":"Johansson","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jtha.2025.09.027_bib41","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.chom.2023.01.006","article-title":"Autophagy controls mucus secretion from intestinal goblet cells by alleviating ER stress","volume":"31","author":"Naama","year":"2023","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.jtha.2025.09.027_bib42","doi-asserted-by":"crossref","first-page":"G430","DOI":"10.1152\/ajpgi.00405.2011","article-title":"An ex vivo method for studying mucus formation, properties, and thickness in human colonic biopsies and mouse small and large intestinal explants","volume":"302","author":"Gustafsson","year":"2012","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.jtha.2025.09.027_bib43","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1084\/jem.20051732","article-title":"Systemic antithrombotic effects of ADAMTS13","volume":"203","author":"Chauhan","year":"2006","journal-title":"J Exp Med"},{"key":"10.1016\/j.jtha.2025.09.027_bib44","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1161\/ATVBAHA.119.312848","article-title":"Formation and resolution of pial microvascular thrombosis in a mouse model of thrombotic thrombocytopenic purpura","volume":"39","author":"Adili","year":"2019","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jtha.2025.09.027_bib45","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1111\/j.1538-7836.2007.02361.x","article-title":"Formation of platelet strings and microthrombi in the presence of ADAMTS-13 inhibitor does not require P-selectin or \u03b23 integrin","volume":"5","author":"Chauhan","year":"2007","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.jtha.2025.09.027_bib46","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1136\/gut.42.4.530","article-title":"Apoptosis is a major mode of cell death caused by ischaemia and ischaemia\/reperfusion injury to the rat intestinal epithelium","volume":"42","author":"Ikeda","year":"1998","journal-title":"Gut"},{"key":"10.1016\/j.jtha.2025.09.027_bib47","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1111\/jth.13696","article-title":"von Willebrand factor and inflammation","volume":"15","author":"Kawecki","year":"2017","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.jtha.2025.09.027_bib48","doi-asserted-by":"crossref","first-page":"3746","DOI":"10.1182\/blood-2006-03-010322","article-title":"P-selectin glycoprotein ligand 1 and \u03b22-integrins cooperate in the adhesion of leukocytes to von Willebrand factor","volume":"108","author":"Pendu","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2025.09.027_bib49","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1055\/s-0037-1616128","article-title":"Adhesive interactions of leukocytes, platelets, and the vessel wall during hemostasis and inflammation","volume":"86","author":"McEver","year":"2001","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jtha.2025.09.027_bib50","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1111\/j.1538-7836.2005.01122.x","article-title":"Platelets adhered to endothelial cell-bound ultra-large von Willebrand factor strings support leukocyte tethering and rolling under high shear stress","volume":"3","author":"Bernardo","year":"2005","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.jtha.2025.09.027_bib51","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0258675","article-title":"Role of ADAMTS13, VWF and F8 genes in deep vein thrombosis","volume":"16","author":"Pagliari","year":"2021","journal-title":"PLoS One"},{"key":"10.1016\/j.jtha.2025.09.027_bib52","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1182\/blood-2016-10-747089","article-title":"ADAMTS13 controls vascular remodeling by modifying VWF reactivity during stroke recovery","volume":"130","author":"Xu","year":"2017","journal-title":"Blood"},{"key":"10.1016\/j.jtha.2025.09.027_bib53","doi-asserted-by":"crossref","first-page":"5217","DOI":"10.1182\/blood-2012-06-439935","article-title":"Protective anti-inflammatory effect of ADAMTS13 on myocardial ischemia\/reperfusion injury in mice","volume":"120","author":"De Meyer","year":"2012","journal-title":"Blood"}],"container-title":["Journal of Thrombosis and Haemostasis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538783625006464?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538783625006464?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T07:23:41Z","timestamp":1778225021000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1538783625006464"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":53,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["S1538783625006464"],"URL":"https:\/\/doi.org\/10.1016\/j.jtha.2025.09.027","relation":{},"ISSN":["1538-7836"],"issn-type":[{"value":"1538-7836","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Microthrombi growth in ADAMTS13 deficiency exacerbates inflammatory bowel disease via mucosal and endothelial dysfunction","name":"articletitle","label":"Article Title"},{"value":"Journal of Thrombosis and Haemostasis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtha.2025.09.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc. on behalf of International Society on Thrombosis and Haemostasis.","name":"copyright","label":"Copyright"}]}}