{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T16:24:38Z","timestamp":1787156678401,"version":"build-2736575974"},"reference-count":57,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["jthjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Thrombosis and Haemostasis"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.jtha.2026.06.005","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T06:40:12Z","timestamp":1781678412000},"page":"3201-3212","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Use of argatroban as a heparin alternative in cardiac surgery\u2014a rapid review of case reports and series"],"prefix":"10.1016","volume":"24","author":[{"given":"Sharon","family":"Bouvette","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4802-4162","authenticated-orcid":false,"given":"Amir L.","family":"Butt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shari C.","family":"Clifton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9768-0417","authenticated-orcid":false,"given":"Kenneth E.","family":"Stewart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul M.","family":"Boylan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2955-4915","authenticated-orcid":false,"given":"Michael A.","family":"Mazzeffi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5051-1365","authenticated-orcid":false,"given":"Kenichi A.","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtha.2026.06.005_bib1","first-page":"820","article-title":"Anticoagulation management and heparin resistance during cardiopulmonary bypass: a survey of Society of Cardiovascular Anesthesiologists Members","volume":"131","author":"Sniecinski","year":"2020","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jtha.2026.06.005_bib2","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1007\/s10047-024-01435-1","article-title":"Contributing factors to heparin resistance during cardiopulmonary bypass","volume":"27","author":"Yamamura","year":"2024","journal-title":"J Artif Organs"},{"key":"10.1016\/j.jtha.2026.06.005_bib3","doi-asserted-by":"crossref","first-page":"2615","DOI":"10.1053\/j.jvca.2025.05.031","article-title":"Activated clotting time measured by hemochron signature elite in adult cardiac surgery: implications for clinical practice","volume":"39","author":"Russo F.M., Artoni A.,","year":"2025","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10.1016\/j.jtha.2026.06.005_bib4","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.athoracsur.2006.09.038","article-title":"Bivalirudin during cardiopulmonary bypass in patients with previous or acute heparin-induced thrombocytopenia and heparin antibodies: results of the CHOOSE-ON trial","volume":"83","author":"Koster","year":"2007","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtha.2026.06.005_bib5","series-title":"Prescribing information: argatroban injection in 0.9% sodium chloride, for intravenous infusion only","year":"2011"},{"key":"10.1016\/j.jtha.2026.06.005_bib6","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1097\/MBC.0b013e328304e00d","article-title":"What is the optimal anticoagulation level with argatroban during percutaneous coronary intervention?","volume":"19","author":"Cruz-Gonzalez","year":"2008","journal-title":"Blood Coagul Fibrinolysis"},{"key":"10.1016\/j.jtha.2026.06.005_bib7","series-title":"Developing PRISMA-RR, a reporting guideline for rapid reviews of primary studies (protocol)","author":"Stevens","year":"2018"},{"key":"10.1016\/j.jtha.2026.06.005_bib8","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.jclinepi.2020.10.007","article-title":"Cochrane Rapid Reviews Methods Group offers evidence-informed guidance to conduct rapid reviews","volume":"130","author":"Garritty","year":"2021","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.jtha.2026.06.005_bib9","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1136\/bmjebm-2017-110853","article-title":"Methodological quality and synthesis of case series and case reports","volume":"23","author":"Murad","year":"2018","journal-title":"BMJ Evid Based Med"},{"key":"10.1016\/j.jtha.2026.06.005_bib10","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1002\/jrsm.1411","article-title":"Risk-of-bias VISualization (robvis): an R package and Shiny web app for visualizing risk-of-bias assessments","volume":"12","author":"McGuinness","year":"2021","journal-title":"Res Synth Methods"},{"key":"10.1016\/j.jtha.2026.06.005_bib11","first-page":"913","article-title":"Finding a common definition of heparin resistance in adult cardiac surgery: communication from the ISTH SSC subcommittee on perioperative and critical care thrombosis and hemostasis","volume":"22","author":"Levy","year":"2024","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.jtha.2026.06.005_bib12","doi-asserted-by":"crossref","first-page":"2626","DOI":"10.1053\/j.jvca.2025.07.001","article-title":"Comparison of two activated clotting time targets during cardiac surgery with cardiopulmonary bypass: a prospective multicenter randomized controlled trial","volume":"39","author":"Gorter","year":"2025","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10.1016\/j.jtha.2026.06.005_bib13","doi-asserted-by":"crossref","first-page":"106","DOI":"10.4103\/0970-9185.92458","article-title":"Challenges encountered with argatroban anticoagulation during cardiopulmonary bypass","volume":"28","author":"Agarwal","year":"2012","journal-title":"J Anaesthesiol Clin Pharmacol"},{"key":"10.1016\/j.jtha.2026.06.005_bib14","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/j.1747-0803.2008.00173.x","article-title":"Argatroban anticoagulation for cardiac surgery with cardiopulmonary bypass in an infant with double outlet right ventricle and a history of heparin-induced thrombocytopenia","volume":"3","author":"Ciccolo","year":"2008","journal-title":"Congenit Heart Dis"},{"key":"10.1016\/j.jtha.2026.06.005_bib15","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1111\/j.1460-9592.2005.01417.x","article-title":"Argatroban for anticoagulation during cardiopulmonary bypass in an infant","volume":"15","author":"Dyke","year":"2005","journal-title":"Paediatr Anaesth"},{"key":"10.1016\/j.jtha.2026.06.005_bib16","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1016\/S0003-4975(02)04782-3","article-title":"Successful use of argatroban as a heparin substitute during cardiopulmonary bypass: heparin-induced thrombocytopenia in a high-risk cardiac surgical patient","volume":"75","author":"Edwards","year":"2003","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtha.2026.06.005_bib17","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1177\/0267659118813043","article-title":"A 24-hour perioperative case study on argatroban use for left ventricle assist device insertion during cardiopulmonary bypass and veno-arterial extracorporeal membrane oxygenation","volume":"34","author":"Fernandes","year":"2019","journal-title":"Perfusion"},{"key":"10.1016\/j.jtha.2026.06.005_bib18","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1510\/icvts.2009.215848","article-title":"Argatroban as a substitute of heparin during cardiopulmonary bypass: a safe alternative?","volume":"10","author":"Follis","year":"2010","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"10.1016\/j.jtha.2026.06.005_bib19","first-page":"383","article-title":"Open heart surgery using cardiopulmonary bypass in a patient with heparin-induced thrombocytopenia","volume":"66","author":"Furukawa","year":"2013","journal-title":"Jpn J Thorac Surg"},{"key":"10.1016\/j.jtha.2026.06.005_bib20","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1067\/mtc.2001.116940","article-title":"The use of argatroban as an anticoagulant for cardiopulmonary bypass in cardiac operations","volume":"122","author":"Furukawa","year":"2001","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtha.2026.06.005_bib21","doi-asserted-by":"crossref","first-page":"e89","DOI":"10.1016\/j.athoracsur.2004.04.037","article-title":"Severe argatroban-induced coagulopathy in a patient with a history of heparin-induced thrombocytopenia","volume":"78","author":"Gasparovic","year":"2004","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtha.2026.06.005_bib22","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1111\/j.1537-2995.2009.02531.x","article-title":"Prolonged elevation of plasma argatroban in a cardiac transplant patient with a suspected history of heparin-induced thrombocytopenia with thrombosis","volume":"50","author":"Genzen","year":"2010","journal-title":"Transfusion"},{"key":"10.1016\/j.jtha.2026.06.005_bib23","first-page":"397","article-title":"Argatroban for a hemodialysis patient with HIT undergoing CABG using argatroban","volume":"61","author":"Goto","year":"2012","journal-title":"Masui"},{"key":"10.1016\/j.jtha.2026.06.005_bib24","article-title":"Anticoagulation with argatroban in a patient with heparin-induced thrombocytopenia and renal insufficiency undergoing orthotopic heart transplantation","volume":"1","author":"Green","year":"2021","journal-title":"Case Rep Anesthesiol"},{"key":"10.1016\/j.jtha.2026.06.005_bib25","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1053\/j.jvca.2018.09.028","article-title":"Rotational thromboelastometry for coagulation management during cardiopulmonary bypass using argatroban","volume":"33","author":"Hirasaki","year":"2019","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10.1016\/j.jtha.2026.06.005_bib26","first-page":"428","article-title":"case of extracorporeal circulation using argatroban for antibody positive heparin-induced thrombocytopenia type II","volume":"42","author":"Horiguchi","year":"2015","journal-title":"Jpn J Extra Corpor Technol"},{"key":"10.1016\/j.jtha.2026.06.005_bib27","first-page":"122","article-title":"Use of argatroban during cardiopulmonary bypass for atrial septal defect with heparin-induced thrombocytopenia after introduction of dialysis","volume":"62","author":"Ishida","year":"2009","journal-title":"Jpn J Thorac Surg"},{"key":"10.1016\/j.jtha.2026.06.005_bib28","doi-asserted-by":"crossref","first-page":"133","DOI":"10.7130\/hokkaidoshakai.35.133","article-title":"A method of extracorporeal circulation for the case of heparin-induced thrombocytopenia","volume":"35","author":"Kashiwa","year":"2008","journal-title":"J Extra Corpor Technol"},{"key":"10.1016\/j.jtha.2026.06.005_bib29","first-page":"112","article-title":"A case of reoperation for paravalvular leak using argatroban for heparin-induced thrombocytopenia","volume":"40","author":"Kato","year":"2011","journal-title":"Jpn J Thorac Surg"},{"key":"10.1016\/j.jtha.2026.06.005_bib30","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s40981-020-0310-6","article-title":"Use of argatroban in combination with nafamostat mesilate in open-heart surgery for a pediatric patient with heparin-induced thrombocytopenia type II: a case report","volume":"6","author":"Kawamoto","year":"2020","journal-title":"JA Clin Rep"},{"key":"10.1016\/j.jtha.2026.06.005_bib31","first-page":"366","article-title":"Management of cardiopulmonary bypass during cardiac surgery for patients with heparin-induced thrombocytopenia","volume":"66","author":"Kondo","year":"2013","journal-title":"Kyobu-Geka: Jpn J Thorac Surg"},{"key":"10.1016\/j.jtha.2026.06.005_bib32","doi-asserted-by":"crossref","first-page":"216","DOI":"10.23736\/S0394-9508.19.04962-3","article-title":"Open-heart surgery in a patient with severe heart failure with heparin-induced thrombocytopenia","volume":"33","author":"Konishi","year":"2020","journal-title":"Chirurgia"},{"key":"10.1016\/j.jtha.2026.06.005_bib33","first-page":"245","article-title":"Cardiac surgery in a patient with heparin-induced thrombocytopenia\u2014cautions with use of the direct thrombin inhibitor, argatroban","volume":"70","author":"Kurup","year":"2006","journal-title":"Conn Med"},{"key":"10.1016\/j.jtha.2026.06.005_bib34","first-page":"365","article-title":"Open heart surgery undergoing cardiopulmonary bypass for the patient with heparin induced thrombocytopenia","volume":"36","author":"Kusano","year":"2009","journal-title":"J Extra Corpor Technol"},{"key":"10.1016\/j.jtha.2026.06.005_bib35","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1177\/1089253215624766","article-title":"Challenging argatroban management of a child on extracorporeal support and subsequent heart transplant","volume":"20","author":"Latham","year":"2016","journal-title":"Semin Cardiothorac Vasc Anesth"},{"key":"10.1016\/j.jtha.2026.06.005_bib36","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1097\/00000542-200402000-00038","article-title":"Argatroban as anticoagulant in cardiopulmonary bypass in an infant and attempted reversal with recombinant activated factor VII","volume":"100","author":"Malherbe","year":"2004","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jtha.2026.06.005_bib37","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1600-0609.2006.00786.x","article-title":"Laber D.A.Argatroban for anticoagulation during cardiac surgery","volume":"78","author":"Martin","year":"2006","journal-title":"Eur J Haematol"},{"key":"10.1016\/j.jtha.2026.06.005_bib38","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1051\/ject\/200537303","article-title":"Cardiopulmonary bypass using argatroban as an anticoagulant for a 6.0-kg pediatric patient","volume":"37","author":"Mejak","year":"2005","journal-title":"J Extra Corpor Technol"},{"key":"10.1016\/j.jtha.2026.06.005_bib39","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1055\/s-0028-1086080","article-title":"Efficacy of argatroban on heparin-induced thrombocytopenia in Japan","volume":"34","author":"Miyata","year":"2008","journal-title":"Semin Thromb Hemost"},{"key":"10.1016\/j.jtha.2026.06.005_bib40","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1016\/j.ejcts.2008.07.035","article-title":"Use of argatroban for anticoagulation during cardiopulmonary bypass in a patient with heparin allergy","volume":"34","author":"Smith","year":"2008","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.jtha.2026.06.005_bib41","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1007\/s00540-013-1629-1","article-title":"Non-recovery of ACT in a patient with heparin-induced thrombocytopenia type II during mitral valve replacement using argatroban anticoagulation","volume":"27","author":"Tanigawa","year":"2013","journal-title":"J Anesth"},{"key":"10.1016\/j.jtha.2026.06.005_bib42","first-page":"1126","article-title":"Aprotinin prolongs activated and nonactivated whole blood clotting time and potentiates the effect of heparin in vitro","volume":"82","author":"Despotis","year":"1996","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jtha.2026.06.005_bib43","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/j.1527-3466.1995.tb00213.x","article-title":"Nafamostat mesilate","volume":"13","author":"Okajima","year":"1995","journal-title":"Cardiovasc Drug Rev"},{"key":"10.1016\/j.jtha.2026.06.005_bib44","doi-asserted-by":"crossref","first-page":"3360","DOI":"10.1182\/bloodadvances.2018024489","article-title":"American Society of Hematology 2018 guidelines for management of venous thromboembolism: heparin-induced thrombocytopenia","volume":"2","author":"Cuker","year":"2018","journal-title":"Blood Adv"},{"key":"10.1016\/j.jtha.2026.06.005_bib45","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1016\/j.jtcvs.2010.07.003","article-title":"Heparinized cardiopulmonary bypass circuits and low systemic anticoagulation: an analysis of nearly 6000 patients undergoing coronary artery bypass grafting","volume":"141","author":"\u00d8vrum","year":"2011","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtha.2026.06.005_bib46","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s00414-016-1480-7","article-title":"Survival after intravenous thrombin prior to cardiopulmonary bypass","volume":"131","author":"Nielsen","year":"2017","journal-title":"Int J Legal Med"},{"key":"10.1016\/j.jtha.2026.06.005_bib47","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1051\/ject\/200537296","article-title":"Use of bivalirudin as an anticoagulant during cardiopulmonary bypass","volume":"37","author":"Veale","year":"2005","journal-title":"J Extra Corpor Technol"},{"key":"10.1016\/j.jtha.2026.06.005_bib48","first-page":"383","article-title":"Bivalirudin monitored with the ecarin clotting time for anticoagulation during cardiopulmonary bypass","volume":"96","author":"Koster","year":"2003","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jtha.2026.06.005_bib49","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1111\/jth.12960","article-title":"Selective disruption of heparin and antithrombin-mediated regulation of human factor IX.","volume":"13","author":"Westmark","year":"2015","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.jtha.2026.06.005_bib50","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1111\/j.1538-7836.2006.01896.x","article-title":"Disposition of tissue factor pathway inhibitor during cardiopulmonary bypass","volume":"4","author":"Donahue","year":"2006","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.jtha.2026.06.005_bib51","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1213\/ANE.0000000000006019","article-title":"Rivaroxaban reduces the dabigatran dose required for anticoagulation during simulated cardiopulmonary bypass","volume":"135","author":"Nadtochiy","year":"2022","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jtha.2026.06.005_bib52","doi-asserted-by":"crossref","first-page":"4443","DOI":"10.1111\/bcp.15431","article-title":"A systematic review and meta-analysis of dabigatran peak and trough concentration in adults","volume":"88","author":"Ng","year":"2022","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.jtha.2026.06.005_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.thromres.2025.109524","article-title":"In vitro anticoagulant effect of nafamostat mesylate in andexanet-induced heparin resistance","volume":"256","author":"Okada","year":"2025","journal-title":"Thromb Res"},{"key":"10.1016\/j.jtha.2026.06.005_bib55","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1213\/ANE.0b013e3181e9ead3","article-title":"A thrombus in the venous reservoir while using bivalirudin in a patient with heparin-induced thrombocytopenia undergoing heart transplantation","volume":"111","author":"Wong","year":"2010","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jtha.2026.06.005_bib56","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1021\/acsptsci.4c00352","article-title":"Anticoagulation during extracorporeal membrane oxygenation (ECMO): a selective inhibitor of activated factor XII compared to heparin in an ex vivo model","volume":"8","author":"Gandini","year":"2025","journal-title":"ACS Pharmacol Transl Sci"},{"key":"10.1016\/j.jtha.2026.06.005_bib57","doi-asserted-by":"crossref","first-page":"3429","DOI":"10.1053\/j.jvca.2020.01.054","article-title":"Perioperative applications of therapeutic plasma exchange in cardiac surgery: a narrative review","volume":"34","author":"Grazioli","year":"2020","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10.1016\/j.jtha.2026.06.005_bib58","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1182\/blood-2014-07-590844","article-title":"Plasma exchange to remove HIT antibodies: dissociation between enzyme-immunoassay and platelet activation test reactivities","volume":"125","author":"Warkentin","year":"2015","journal-title":"Blood"}],"container-title":["Journal of Thrombosis and Haemostasis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538783626003843?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538783626003843?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T15:29:24Z","timestamp":1787153364000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1538783626003843"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":57,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["S1538783626003843"],"URL":"https:\/\/doi.org\/10.1016\/j.jtha.2026.06.005","relation":{},"ISSN":["1538-7836"],"issn-type":[{"value":"1538-7836","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Use of argatroban as a heparin alternative in cardiac surgery\u2014a rapid review of case reports and series","name":"articletitle","label":"Article Title"},{"value":"Journal of Thrombosis and Haemostasis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtha.2026.06.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 International Society on Thrombosis and Haemostasis. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}