{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T17:05:58Z","timestamp":1793120758715,"version":"4.5.0"},"reference-count":120,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32260814"],"award-info":[{"award-number":["32260814"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013072","name":"Major Science and Technology Project of Hainan Province","doi-asserted-by":"publisher","award":["ZDYF2025XDNY068"],"award-info":[{"award-number":["ZDYF2025XDNY068"]}],"id":[{"id":"10.13039\/501100013072","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFF0724701"],"award-info":[{"award-number":["2023YFF0724701"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Thermal Biology"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.jtherbio.2025.104264","type":"journal-article","created":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T15:55:21Z","timestamp":1757001321000},"page":"104264","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Integration of multi-omics resources reveals genetic features associated with environmental adaptation in the Wuzhishan pig genome"],"prefix":"10.1016","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9655-3595","authenticated-orcid":false,"given":"Ziqi","family":"Zhong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinfeng","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deyou","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtherbio.2025.104264_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2019.134399","article-title":"Herbs as thermoregulatory agents in poultry: an overview","volume":"703","author":"Abd El-Hack","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.jtherbio.2025.104264_bib2","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/s41586-020-2371-0","article-title":"Mapping and characterization of structural variation in 17,795 human genomes","volume":"583","author":"Abel","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.jtherbio.2025.104264_bib3","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1101\/gr.114876.110","article-title":"CNVnator: an approach to discover, genotype, and characterize typical and atypical CNVs from family and population genome sequencing","volume":"21","author":"Abyzov","year":"2011","journal-title":"Genome Res."},{"key":"10.1016\/j.jtherbio.2025.104264_bib4","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0056001","article-title":"Genetic diversity, linkage disequilibrium and selection signatures in Chinese and Western pigs revealed by genome-wide SNP markers","volume":"8","author":"Ai","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jtherbio.2025.104264_bib5","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1101\/gr.094052.109","article-title":"Fast model-based estimation of ancestry in unrelated individuals","volume":"19","author":"Alexander","year":"2009","journal-title":"Genome Res."},{"key":"10.1016\/j.jtherbio.2025.104264_bib6","doi-asserted-by":"crossref","first-page":"6078","DOI":"10.1038\/s41467-021-26360-2","article-title":"PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC","volume":"12","author":"Appel","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jtherbio.2025.104264_bib7","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25179397","article-title":"Genetic diversity, selection signatures, and genome-wide Association Study identify candidate genes related to litter size in Hu sheep","volume":"25","author":"Bao","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jtherbio.2025.104264_bib8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0239143","article-title":"Genetic variations (eQTLs) in muscle transcriptome and mitochondrial genes, and trans-eQTL molecular pathways in feed efficiency from Danish breeding pigs","volume":"15","author":"Carmelo","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.jtherbio.2025.104264_bib9","article-title":"TBtools-II: a \"one for all, all for one\" bioinformatics platform for biological big-data mining","volume":"22","author":"Chen","year":"2023","journal-title":"Mol. Plant"},{"key":"10.1016\/j.jtherbio.2025.104264_bib10","doi-asserted-by":"crossref","first-page":"i884","DOI":"10.1093\/bioinformatics\/bty560","article-title":"Fastp: an ultra-fast all-in-one FASTQ preprocessor","volume":"34","author":"Chen","year":"2018","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jtherbio.2025.104264_bib11","doi-asserted-by":"crossref","first-page":"2445","DOI":"10.1042\/CS20190654","article-title":"The immune niche of the liver","volume":"135","author":"Cheng","year":"2021","journal-title":"Clin. Sci. (Lond.)"},{"key":"10.1016\/j.jtherbio.2025.104264_bib12","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1038\/s41586-020-2287-8","article-title":"A structural variation reference for medical and population genetics","volume":"581","author":"Collins","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.jtherbio.2025.104264_bib13","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/j.1439-0388.2012.01003.x","article-title":"Estimation of historical effective population size using linkage disequilibria with marker data","volume":"129","author":"Corbin","year":"2012","journal-title":"J. Anim. Breed. Genet."},{"key":"10.1016\/j.jtherbio.2025.104264_bib14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0218862","article-title":"Indel detection from Whole Genome Sequencing data and association with lipid metabolism in pigs","volume":"14","author":"Crespo-Piazuelo","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.jtherbio.2025.104264_bib15","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/978-981-15-0602-4_27","article-title":"Autophagy and the immune response","volume":"1206","author":"Cui","year":"2019","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.jtherbio.2025.104264_bib16","doi-asserted-by":"crossref","first-page":"2156","DOI":"10.1093\/bioinformatics\/btr330","article-title":"The variant call format and VCFtools","volume":"27","author":"Danecek","year":"2011","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jtherbio.2025.104264_bib17","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1007\/s11250-022-03428-9","article-title":"Estimation of genetic parameters and inbreeding depression in Piau pig breed","volume":"55","author":"De Oliveira","year":"2023","journal-title":"Trop. Anim. Health Prod."},{"key":"10.1016\/j.jtherbio.2025.104264_bib18","doi-asserted-by":"crossref","first-page":"6424","DOI":"10.1016\/j.cell.2024.10.026","article-title":"The chromosome folding problem and how cells solve it","volume":"187","author":"Dekker","year":"2024","journal-title":"Cell"},{"key":"10.1016\/j.jtherbio.2025.104264_bib19","doi-asserted-by":"crossref","first-page":"P3","DOI":"10.1186\/gb-2003-4-5-p3","article-title":"DAVID: database for annotation, visualization, and integrated discovery","volume":"4","author":"Dennis","year":"2003","journal-title":"Genome Biol."},{"key":"10.1016\/j.jtherbio.2025.104264_bib20","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.3390\/genes14071503","article-title":"Identification of ROH Islands conserved through generations in pigs belonging to the nero Lucano Breed","volume":"14","author":"Di Gregorio","year":"2023","journal-title":"Genes"},{"key":"10.1016\/j.jtherbio.2025.104264_bib21","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1111\/nph.14103","article-title":"Transcriptome response of Lolium arundinaceum to its fungal endophyte Epichloe coenophiala","volume":"213","author":"Dinkins","year":"2017","journal-title":"New Phytol."},{"key":"10.1016\/j.jtherbio.2025.104264_bib22","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.antiviral.2019.02.018","article-title":"African swine fever","volume":"165","author":"Dixon","year":"2019","journal-title":"Antivir. Res."},{"key":"10.1016\/j.jtherbio.2025.104264_bib23","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-12573-3","article-title":"LRRC25 functions as an inhibitor of NF-\u03baB signaling pathway by promoting p65\/RelA for Autophagic Degradation","volume":"7","author":"Feng","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jtherbio.2025.104264_bib122","unstructured":"Food and Agriculture Organization of the United Nations (FAO), 2000. Secondary guidelines for development of national farm animal genetic resources management plans: Management of small populations at risk. Food and Agriculture Organization of the United Nations, Rome."},{"key":"10.1016\/j.jtherbio.2025.104264_bib24","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1186\/1471-2164-14-784","article-title":"Genome wide analysis reveals single nucleotide polymorphisms associated with fatness and putative novel copy number variants in three pig breeds","volume":"14","author":"Fowler","year":"2013","journal-title":"BMC Genom."},{"key":"10.1016\/j.jtherbio.2025.104264_bib25","doi-asserted-by":"crossref","first-page":"D1312","DOI":"10.1093\/nar\/gkac936","article-title":"IAnimal: a cross-species omics knowledgebase for animals","volume":"51","author":"Fu","year":"2023","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jtherbio.2025.104264_bib26","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1186\/1471-2105-10-131","article-title":"SNEP: simultaneous detection of nucleotide and expression polymorphisms using Affymetrix GeneChip","volume":"10","author":"Fujisawa","year":"2009","journal-title":"BMC Bioinf."},{"key":"10.1016\/j.jtherbio.2025.104264_bib27","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/1471-2164-10-550","article-title":"A whole genome Bayesian scan for adaptive genetic divergence in West African cattle","volume":"10","author":"Gautier","year":"2009","journal-title":"BMC Genom."},{"key":"10.1016\/j.jtherbio.2025.104264_bib28","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1093\/hmg\/ddi493","article-title":"Extended tracts of homozygosity in outbred human populations","volume":"15","author":"Gibson","year":"2006","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.jtherbio.2025.104264_bib29","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s12711-020-00599-7","article-title":"A publicly available repository of ROH islands reveals signatures of selection in different livestock and pet species","volume":"53","author":"Gorssen","year":"2021","journal-title":"Genet. Sel. Evol."},{"key":"10.1016\/j.jtherbio.2025.104264_bib30","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s12863-017-0473-y","article-title":"Genetic diversity, extent of linkage disequilibrium and persistence of gametic phase in Canadian pigs","volume":"18","author":"Grossi","year":"2017","journal-title":"BMC Genet."},{"key":"10.1016\/j.jtherbio.2025.104264_bib31","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1186\/s12885-022-09410-w","article-title":"Systematic analysis of the expression and prognostic value of ITPR1 and correlation with tumor infiltrating immune cells in breast cancer","volume":"22","author":"Han","year":"2022","journal-title":"BMC Cancer"},{"key":"10.1016\/j.jtherbio.2025.104264_bib32","doi-asserted-by":"crossref","DOI":"10.1093\/gpbjnl\/qzaf016","article-title":"PIGOME: an integrated and comprehensive multi-omics database for Pig functional genomics studies","author":"Han","year":"2025","journal-title":"Genom. Proteom. Bioinform."},{"key":"10.1016\/j.jtherbio.2025.104264_bib33","doi-asserted-by":"crossref","first-page":"699","DOI":"10.3390\/ani14050699","article-title":"Unveiling the genetic secrets of chinese indigenous pigs from guizhou province: diversity, evolution and candidate genes affecting pig coat color","volume":"14","author":"Hu","year":"2024","journal-title":"Animals"},{"key":"10.1016\/j.jtherbio.2025.104264_bib34","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1186\/s12864-022-08583-9","article-title":"Genome-wide detection of genetic structure and runs of homozygosity analysis in Anhui indigenous and Western commercial pig breeds using PorcineSNP80k data","volume":"23","author":"Jiang","year":"2022","journal-title":"BMC Genom."},{"key":"10.1016\/j.jtherbio.2025.104264_bib35","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.708908","article-title":"PI3K in T cell adhesion and trafficking","volume":"12","author":"Johansen","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jtherbio.2025.104264_bib36","doi-asserted-by":"crossref","DOI":"10.15252\/embr.201947963","article-title":"Arpin is critical for phagocytosis in macrophages and is targeted by human rhinovirus","volume":"21","author":"Jubrail","year":"2020","journal-title":"EMBO Rep."},{"key":"10.1016\/j.jtherbio.2025.104264_bib37","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1095\/biolreprod.108.073866","article-title":"CABS1 is a novel calcium-binding protein specifically expressed in elongate spermatids of mice","volume":"80","author":"Kawashima","year":"2009","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.jtherbio.2025.104264_bib38","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1038\/s41588-021-00924-w","article-title":"A compendium of uniformly processed human gene expression and splicing quantitative trait loci","volume":"53","author":"Kerimov","year":"2021","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jtherbio.2025.104264_bib39","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1080\/10495398.2021.1972005","article-title":"Physiological dynamics in broiler chickens under heat stress and possible mitigation strategies","volume":"34","author":"Khan","year":"2023","journal-title":"Anim. Biotechnol."},{"key":"10.1016\/j.jtherbio.2025.104264_bib40","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.3390\/biom10111525","article-title":"Hyaluronan: metabolism and function","volume":"10","author":"Kobayashi","year":"2020","journal-title":"Biomolecules"},{"key":"10.1016\/j.jtherbio.2025.104264_bib41","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1093\/molbev\/msw054","article-title":"MEGA7: molecular evolutionary genetics analysis version 7.0 for bigger datasets","volume":"33","author":"Kumar","year":"2016","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.jtherbio.2025.104264_bib42","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2020.538640","article-title":"Whole genome sequence data provides novel insights into the genetic Architecture of meat quality traits in beef","volume":"11","author":"Leal-Guti\u00e9rrez","year":"2020","journal-title":"Front. Genet."},{"key":"10.1016\/j.jtherbio.2025.104264_bib43","doi-asserted-by":"crossref","first-page":"W293","DOI":"10.1093\/nar\/gkab301","article-title":"Interactive Tree of Life (iTOL) v5: an online tool for phylogenetic tree display and annotation","volume":"49","author":"Letunic","year":"2021","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jtherbio.2025.104264_bib44","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1093\/bioinformatics\/btp324","article-title":"Fast and accurate short read alignment with Burrows-Wheeler transform","volume":"25","author":"Li","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jtherbio.2025.104264_bib45","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1093\/bioinformatics\/btp352","article-title":"The Sequence Alignment\/Map format and SAMtools","volume":"25","author":"Li","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jtherbio.2025.104264_bib46","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.jgg.2023.11.005","article-title":"Characterizing structural variants based on graph-genotyping provides insights into pig domestication and local adaption","volume":"51","author":"Li","year":"2024","journal-title":"J Genet Genomics"},{"key":"10.1016\/j.jtherbio.2025.104264_bib47","doi-asserted-by":"crossref","DOI":"10.1093\/jas\/skae189","article-title":"Estimation of genotype by environmental interaction for litter traits by reaction norm model in Taiwan Landrace sows","volume":"102","author":"Lin","year":"2024","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.jtherbio.2025.104264_bib48","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2201129119","article-title":"Sialic acids on B cells are crucial for their survival and provide protection against apoptosis","volume":"119","author":"Linder","year":"2022","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jtherbio.2025.104264_bib49","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0243911","article-title":"The pharmacodynamic and differential gene expression analysis of PPAR \u03b1\/\u03b4 agonist GFT505 in CDAHFD-induced NASH model","volume":"15","author":"Liu","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.jtherbio.2025.104264_bib50","article-title":"Variant callers for next-generation sequencing data: a comparison study","volume":"8","author":"Liu","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jtherbio.2025.104264_bib51","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/4091978","article-title":"The overexpression of SLC25A13 predicts poor prognosis and is correlated with immune cell infiltration in patients with skin cutaneous Melanoma","volume":"2022","author":"Lv","year":"2022","journal-title":"Dis. Markers"},{"key":"10.1016\/j.jtherbio.2025.104264_bib52","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1095\/biolreprod.107.064659","article-title":"KATP channel subunits are expressed in the epididymal epithelium in several mammalian species","volume":"79","author":"Lybaert","year":"2008","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.jtherbio.2025.104264_bib53","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/j.omtn.2019.10.030","article-title":"Whole-Transcriptome analysis of APP\/PS1 mouse brain and identification of circRNA-miRNA-mRNA networks to investigate AD pathogenesis","volume":"18","author":"Ma","year":"2019","journal-title":"Mol. Ther. Nucleic Acids"},{"key":"10.1016\/j.jtherbio.2025.104264_bib54","doi-asserted-by":"crossref","DOI":"10.1093\/jas\/skae030","article-title":"Investigating intestinal mast cell dynamics during acute heat stress in growing pigs","volume":"102","author":"Mayorga","year":"2024","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.jtherbio.2025.104264_bib55","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.theriogenology.2020.05.023","article-title":"Biology of heat stress; the nexus between intestinal hyperpermeability and swine reproduction","volume":"154","author":"Mayorga","year":"2020","journal-title":"Theriogenology"},{"key":"10.1016\/j.jtherbio.2025.104264_bib56","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1101\/gr.107524.110","article-title":"The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data","volume":"20","author":"Mckenna","year":"2010","journal-title":"Genome Res."},{"key":"10.1016\/j.jtherbio.2025.104264_bib57","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.ajhg.2008.08.007","article-title":"Runs of homozygosity in European populations","volume":"83","author":"Mcquillan","year":"2008","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.jtherbio.2025.104264_bib58","doi-asserted-by":"crossref","first-page":"6820","DOI":"10.1158\/0008-5472.CAN-14-0303","article-title":"ITPR1 protects renal cancer cells against natural killer cells by inducing autophagy","volume":"74","author":"Messai","year":"2014","journal-title":"Cancer Res."},{"key":"10.1016\/j.jtherbio.2025.104264_bib59","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1186\/s12885-019-5867-y","article-title":"APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression","volume":"19","author":"Mohamed","year":"2019","journal-title":"BMC Cancer"},{"key":"10.1016\/j.jtherbio.2025.104264_bib60","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1002\/cm.21471","article-title":"APC2 associates with the actin cortex through a multipart mechanism to regulate cortical actin organization and dynamics in the Drosophila ovary","volume":"75","author":"Molinar-Inglis","year":"2018","journal-title":"Cytoskeleton"},{"key":"10.1016\/j.jtherbio.2025.104264_bib61","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.exphem.2005.10.012","article-title":"Acetylsalicylic acid-induced release of HSP70 from mast cells results in cell activation through TLR pathway","volume":"34","author":"Mortaz","year":"2006","journal-title":"Exp. Hematol."},{"key":"10.1016\/j.jtherbio.2025.104264_bib62","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1385\/IR:31:3:189","article-title":"Immunologic roles of hyaluronan","volume":"31","author":"Mummert","year":"2005","journal-title":"Immunol. Res."},{"key":"10.1016\/j.jtherbio.2025.104264_bib63","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1097\/SHK.0000000000001846","article-title":"Therapeutic effects of hyaluronic acid against cytotoxic extracellular vesicles released during Pseudomonas Aeruginosa Pneumonia","volume":"57","author":"Naito","year":"2022","journal-title":"Shock"},{"key":"10.1016\/j.jtherbio.2025.104264_bib64","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1038\/s10038-022-01112-2","article-title":"The mutation spectrum of SLC25A13 gene in citrin deficiency: identification of novel mutations in Vietnamese pediatric cohort with neonatal intrahepatic cholestasis","volume":"68","author":"Nguyen","year":"2023","journal-title":"J. Hum. Genet."},{"key":"10.1016\/j.jtherbio.2025.104264_bib65","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1080\/1744666X.2021.1945443","article-title":"Phosphatidylinositol 3-kinase signaling and immune regulation: insights into disease pathogenesis and clinical implications","volume":"17","author":"Nguyen","year":"2021","journal-title":"Expert Rev Clin Immunol"},{"key":"10.1016\/j.jtherbio.2025.104264_bib66","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1186\/s12864-021-07610-5","article-title":"Characterization of a haplotype-reference panel for genotyping by low-pass sequencing in Swiss large white pigs","volume":"22","author":"Noskova","year":"2021","journal-title":"BMC Genom."},{"key":"10.1016\/j.jtherbio.2025.104264_bib67","doi-asserted-by":"crossref","first-page":"2670","DOI":"10.1172\/JCI97944","article-title":"Phospholipid signaling in innate immune cells","volume":"128","author":"O'Donnell","year":"2018","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.jtherbio.2025.104264_bib68","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/s12864-017-4365-3","article-title":"Assessment of runs of homozygosity islands and estimates of genomic inbreeding in Gyr (Bos indicus) dairy cattle","volume":"19","author":"Peripolli","year":"2018","journal-title":"BMC Genom."},{"key":"10.1016\/j.jtherbio.2025.104264_bib69","first-page":"777","article-title":"Obesity significantly alters the human sperm proteome, with potential implications for fertility","volume":"37","author":"Pini","year":"2020","journal-title":"J. Anim. Breed. Genet."},{"key":"10.1016\/j.jtherbio.2025.104264_bib70","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1086\/519795","article-title":"PLINK: a tool set for whole-genome association and population-based linkage analyses","volume":"81","author":"Purcell","year":"2007","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.jtherbio.2025.104264_bib71","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-52837-8","article-title":"LncRNA GABPB1-AS1 and GABPB1 regulate oxidative stress during erastin-induced ferroptosis in HepG2 hepatocellular carcinoma cells","volume":"9","author":"Qi","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jtherbio.2025.104264_bib72","doi-asserted-by":"crossref","first-page":"i333","DOI":"10.1093\/bioinformatics\/bts378","article-title":"DELLY: structural variant discovery by integrated paired-end and split-read analysis","volume":"28","author":"Rausch","year":"2012","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jtherbio.2025.104264_bib73","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1186\/s12711-021-00664-9","article-title":"A genome-wide scan to identify signatures of selection in two Iranian indigenous chicken ecotypes","volume":"53","author":"Rostamzadeh Mahdabi","year":"2021","journal-title":"Genet. Sel. Evol."},{"key":"10.1016\/j.jtherbio.2025.104264_bib74","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2212124120","article-title":"Biodiversity and pollination benefits trade off against profit in an intensive farming system","volume":"120","author":"Scheper","year":"2023","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jtherbio.2025.104264_bib75","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/j.1439-0388.2010.00887.x","article-title":"Candidate gene expression and intramuscular fat content in pigs","volume":"128","author":"Serao","year":"2011","journal-title":"J. Anim. Breed. Genet."},{"key":"10.1016\/j.jtherbio.2025.104264_bib76","doi-asserted-by":"crossref","first-page":"9274","DOI":"10.1038\/s41467-024-53692-6","article-title":"Integrative 3D genomics with multi-omics analysis and functional validation of genetic regulatory mechanisms of abdominal fat deposition in chickens","volume":"15","author":"Shen","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jtherbio.2025.104264_bib77","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/s40104-020-00447-0","article-title":"Estimation of inbreeding and identification of regions under heavy selection based on runs of homozygosity in a large White pig population","volume":"11","author":"Shi","year":"2020","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.1016\/j.jtherbio.2025.104264_bib78","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1017\/S1751731120001263","article-title":"The effect of divergent selection for intramuscular fat on the domestic rabbit genome","volume":"14","author":"Sosa-Madrid","year":"2020","journal-title":"Animal"},{"key":"10.1016\/j.jtherbio.2025.104264_bib79","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2020.118974","article-title":"Intestinal sodium\/glucose cotransporter 3 expression is epithelial and downregulated in obesity","volume":"267","author":"Sotak","year":"2021","journal-title":"Life Sci."},{"key":"10.1016\/j.jtherbio.2025.104264_bib80","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1111\/jbg.12438","article-title":"Genome-wide association study for age at puberty in young Nelore bulls","volume":"137","author":"Stafuzza","year":"2020","journal-title":"J. Anim. Breed. Genet."},{"key":"10.1016\/j.jtherbio.2025.104264_bib81","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1262\/jrd.49.347","article-title":"Molecular mechanisms underlying pig oocyte maturation and fertilization","volume":"49","author":"Sun","year":"2003","journal-title":"J. Reprod. Dev."},{"key":"10.1016\/j.jtherbio.2025.104264_bib82","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.theriogenology.2014.08.003","article-title":"Thyroid hormone inhibits the proliferation of piglet Sertoli cell via PI3K signaling pathway","volume":"83","author":"Sun","year":"2015","journal-title":"Theriogenology"},{"key":"10.1016\/j.jtherbio.2025.104264_bib83","doi-asserted-by":"crossref","first-page":"2824","DOI":"10.1093\/molbev\/msu211","article-title":"Selscan: an efficient multithreaded program to perform EHH-based scans for positive selection","volume":"31","author":"Szpiech","year":"2014","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.jtherbio.2025.104264_bib84","doi-asserted-by":"crossref","DOI":"10.1111\/and.13778","article-title":"Verapamil-induced ion channel and miRNA expression changes in rat testis and\/or spermatozoa may be associated with male infertility","volume":"52","author":"Tektemur","year":"2020","journal-title":"Andrologia"},{"key":"10.1016\/j.jtherbio.2025.104264_bib85","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/s41588-023-01585-7","article-title":"A compendium of genetic regulatory effects across pig tissues","volume":"56","author":"Teng","year":"2024","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jtherbio.2025.104264_bib86","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s12711-016-0196-y","article-title":"Population structure and genome characterization of local pig breeds in Russia, Belorussia, Kazakhstan and Ukraine","volume":"48","author":"Traspov","year":"2016","journal-title":"Genet. Sel. Evol."},{"key":"10.1016\/j.jtherbio.2025.104264_bib87","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2021.129219","article-title":"Screening out important substances for distinguishing Chinese indigenous pork and hybrid pork and identifying different pork muscles by analyzing the fatty acid and nucleotide contents","volume":"350","author":"Tu","year":"2021","journal-title":"Food Chem."},{"key":"10.1016\/j.jtherbio.2025.104264_bib88","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.3390\/ani11051331","article-title":"The Nero Lucano pig breed: recovery and variability","volume":"11","author":"Valluzzi","year":"2021","journal-title":"Animals"},{"key":"10.1016\/j.jtherbio.2025.104264_bib89","doi-asserted-by":"crossref","first-page":"e41","DOI":"10.1371\/journal.pgen.0020041","article-title":"Assumption-free estimation of heritability from genome-wide identity-by-descent sharing between full siblings","volume":"2","author":"Visscher","year":"2006","journal-title":"PLoS Genet."},{"key":"10.1016\/j.jtherbio.2025.104264_bib90","doi-asserted-by":"crossref","first-page":"3620","DOI":"10.1038\/s41467-022-31388-z","article-title":"Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level","volume":"13","author":"Wang","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jtherbio.2025.104264_bib91","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.3390\/ani13111835","article-title":"Genome-Wide Re-Sequencing data reveals the population structure and selection signatures of Tunchang pigs in China","volume":"13","author":"Wang","year":"2023","journal-title":"Animals"},{"key":"10.1016\/j.jtherbio.2025.104264_bib92","article-title":"Estimation of genetic variability and identification of regions under selection based on runs of homozygosity in Beijing-You chickens","volume":"102","author":"Wang","year":"2023","journal-title":"Poult. Sci."},{"key":"10.1016\/j.jtherbio.2025.104264_bib93","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkq603","article-title":"ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data","volume":"38","author":"Wang","year":"2010","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jtherbio.2025.104264_bib94","article-title":"Whole-genome sequence analysis reveals selection signatures for important economic traits in Xiang pigs","volume":"12","author":"Wang","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jtherbio.2025.104264_bib95","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1111\/eva.13124","article-title":"Whole-genome SNP markers reveal conservation status, signatures of selection, and introgression in Chinese Laiwu pigs","volume":"14","author":"Wang","year":"2021","journal-title":"Evol Appl"},{"key":"10.1016\/j.jtherbio.2025.104264_bib96","article-title":"Genome-Wide assessment characteristics of genes overlapping copy number variation regions in duroc purebred population","volume":"12","author":"Wang","year":"2021","journal-title":"Front. Genet."},{"key":"10.1016\/j.jtherbio.2025.104264_bib97","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1111\/age.12993","article-title":"Whole-genome sequencing reveals breed-differential CNVs between Tongcheng and Large White pigs","volume":"51","author":"Wu","year":"2020","journal-title":"Anim. Genet."},{"key":"10.1016\/j.jtherbio.2025.104264_bib98","article-title":"Genome-Wide assessment of runs of homozygosity and estimates of genomic inbreeding in a Chinese composite pig breed","volume":"12","author":"Xu","year":"2021","journal-title":"Front. Genet."},{"key":"10.1016\/j.jtherbio.2025.104264_bib99","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.ajhg.2010.11.011","article-title":"GCTA: a tool for genome-wide complex trait analysis","volume":"88","author":"Yang","year":"2011","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.jtherbio.2025.104264_bib100","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1186\/s13059-024-03288-6","article-title":"Structural variant landscapes reveal convergent signatures of evolution in sheep and goats","volume":"25","author":"Yang","year":"2024","journal-title":"Genome Biol."},{"key":"10.1016\/j.jtherbio.2025.104264_bib101","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1186\/s13059-024-03253-3","article-title":"Mapping and functional characterization of structural variation in 1060 pig genomes","volume":"25","author":"Yang","year":"2024","journal-title":"Genome Biol."},{"key":"10.1016\/j.jtherbio.2025.104264_bib102","article-title":"Population genetic structure and selection signature analysis of Beijing Black pig","volume":"13","author":"Yang","year":"2022","journal-title":"Front. Genet."},{"key":"10.1016\/j.jtherbio.2025.104264_bib103","doi-asserted-by":"crossref","first-page":"13475","DOI":"10.1002\/ece3.8071","article-title":"Comparative transcriptome provides insights into the selection adaptation between wild and farmed foxes","volume":"11","author":"Yang","year":"2021","journal-title":"Ecol. Evol."},{"key":"10.1016\/j.jtherbio.2025.104264_bib104","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2022.910521","article-title":"Genetic diversity and population structure of Tongcheng pigs in China using whole-genome SNP chip","volume":"13","author":"Yuan","year":"2022","journal-title":"Front. Genet."},{"key":"10.1016\/j.jtherbio.2025.104264_bib105","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1093\/bioinformatics\/bty875","article-title":"PopLDdecay: a fast and effective tool for linkage disequilibrium decay analysis based on variant call format files","volume":"35","author":"Zhang","year":"2019","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jtherbio.2025.104264_bib106","article-title":"Identification of copy number variations and selection signatures in wannan spotted pigs by whole genome sequencing data: a preliminary Study","volume":"14","author":"Zhang","year":"2024","journal-title":"Animals"},{"key":"10.1016\/j.jtherbio.2025.104264_bib107","article-title":"Copy number variants selected during pig domestication inferred from whole genome resequencing","volume":"11","author":"Zhang","year":"2024","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.jtherbio.2025.104264_bib108","doi-asserted-by":"crossref","first-page":"712","DOI":"10.5713\/ajas.19.0289","article-title":"Genomic analysis reveals selection signatures of the Wannan Black pig during domestication and breeding","volume":"33","author":"Zhang","year":"2020","journal-title":"Asian-Australas. J. Anim. Sci."},{"key":"10.1016\/j.jtherbio.2025.104264_bib109","article-title":"Identification of signatures of selection by whole-genome resequencing of a Chinese native pig","volume":"11","author":"Zhang","year":"2020","journal-title":"Front. Genet."},{"key":"10.1016\/j.jtherbio.2025.104264_bib110","doi-asserted-by":"crossref","DOI":"10.3390\/genes13112026","article-title":"Population structure and selection signatures underlying domestication inferred from genome-wide copy number variations in Chinese Indigenous pigs","volume":"13","author":"Zhang","year":"2022","journal-title":"Genes"},{"key":"10.1016\/j.jtherbio.2025.104264_bib111","article-title":"Cabs1 maintains structural integrity of mouse sperm flagella during epididymal transit of sperm","volume":"22","author":"Zhang","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"7","key":"10.1016\/j.jtherbio.2025.104264_bib112","doi-asserted-by":"crossref","DOI":"10.1093\/g3journal\/jkac118","article-title":"Estimate of inbreeding depression on growth and reproductive traits in a large White pig population","volume":"12","author":"Zhang","year":"2022","journal-title":"G3 (Bethesda)"},{"key":"10.1016\/j.jtherbio.2025.104264_bib113","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.cell.2015.12.057","article-title":"NF-\u03baB restricts inflammasome activation via elimination of damaged mitochondria","volume":"164","author":"Zhong","year":"2016","journal-title":"Cell"},{"issue":"12","key":"10.1016\/j.jtherbio.2025.104264_bib114","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.3390\/ani13122010","article-title":"Evaluation of the genetic diversity, population structure and selection signatures of three native Chinese pig populations","volume":"13","author":"Zhong","year":"2023","journal-title":"Animals"},{"key":"10.1016\/j.jtherbio.2025.104264_bib115","doi-asserted-by":"crossref","DOI":"10.1016\/j.animal.2023.100882","article-title":"Genome-wide scans for selection signatures in indigenous pigs revealed candidate genes relating to heat tolerance","volume":"17","author":"Zhong","year":"2023","journal-title":"Animal"},{"key":"10.1016\/j.jtherbio.2025.104264_bib116","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2021.731355","article-title":"HandyCNV: standardized summary, annotation, comparison, and visualization of copy number variant, copy number variation Region, and runs of homozygosity","volume":"12","author":"Zhou","year":"2021","journal-title":"Front. Genet."},{"key":"10.1016\/j.jtherbio.2025.104264_bib117","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/s40104-023-00863-y","article-title":"Improving the accuracy of genomic prediction for meat quality traits using whole genome sequence data in pigs","volume":"14","author":"Zhuang","year":"2023","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.1016\/j.jtherbio.2025.104264_bib118","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1186\/s40104-023-00929-x","article-title":"Associations of genome-wide structural variations with phenotypic differences in cross-bred Eurasian pigs","volume":"14","author":"Zong","year":"2023","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.1016\/j.jtherbio.2025.104264_bib119","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/s12711-022-00718-6","article-title":"Genetic diversity and population structure of six autochthonous pig breeds from Croatia, Serbia, and Slovenia","volume":"54","author":"Zorc","year":"2022","journal-title":"Genet. Sel. Evol."}],"container-title":["Journal of Thermal Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306456525002219?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306456525002219?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T20:36:51Z","timestamp":1772829411000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306456525002219"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":120,"alternative-id":["S0306456525002219"],"URL":"https:\/\/doi.org\/10.1016\/j.jtherbio.2025.104264","relation":{},"ISSN":["0306-4565"],"issn-type":[{"value":"0306-4565","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Integration of multi-omics resources reveals genetic features associated with environmental adaptation in the Wuzhishan pig genome","name":"articletitle","label":"Article Title"},{"value":"Journal of Thermal Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtherbio.2025.104264","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"104264"}}