{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T15:36:37Z","timestamp":1792856197075,"version":"4.5.0"},"reference-count":142,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014717","name":"Youth Science Fund Project","doi-asserted-by":"publisher","award":["82204780"],"award-info":[{"award-number":["82204780"]}],"id":[{"id":"10.13039\/100014717","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Thermal Biology"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.jtherbio.2026.104579","type":"journal-article","created":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T15:04:17Z","timestamp":1790348657000},"page":"104579","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Skin thermal damage as an independent pathophysiological entity: Molecular mechanisms distinct from photoaging and implications for systemic conditioning strategies"],"prefix":"10.1016","volume":"141","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-6549-654X","authenticated-orcid":false,"given":"Huiting","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanbai","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yihao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weibo","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujing","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangzhou","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtherbio.2026.104579_bib1","doi-asserted-by":"crossref","first-page":"9602","DOI":"10.1039\/C6CP00865H","article-title":"Direct measurement of the tryptophan-mediated photocleavage kinetics of a protein disulfide bond","volume":"18","author":"Abaskharon","year":"2016","journal-title":"Phys. Chem. Chem. Phys. PCCP"},{"key":"10.1016\/j.jtherbio.2026.104579_bib2","doi-asserted-by":"crossref","first-page":"RP95618","DOI":"10.7554\/eLife.95618.4","article-title":"Diverging roles of TRPV1 and TRPM2 in warm-temperature detection","volume":"13","author":"Abd El Hay","year":"2025","journal-title":"eLife"},{"key":"10.1016\/j.jtherbio.2026.104579_bib3","doi-asserted-by":"crossref","DOI":"10.1242\/jcs.245589","article-title":"Perinuclear mitochondrial clustering, increased ROS levels, and HIF1 are required for the activation of HSF1 by heat stress","volume":"133","author":"Agarwal","year":"2020","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.jtherbio.2026.104579_bib5","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.3390\/cimb46030126","article-title":"Ultraviolet radiation biological and medical implications","volume":"46","author":"Al-Sadek","year":"2024","journal-title":"Curr. Issues Mol. Biol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib4","doi-asserted-by":"crossref","first-page":"448","DOI":"10.3390\/antiox9050448","article-title":"Oxidative stress and photodynamic therapy of skin cancers: mechanisms, challenges and promising developments","volume":"9","author":"Allegra","year":"2020","journal-title":"Antioxidants"},{"key":"10.1016\/j.jtherbio.2026.104579_bib6","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkaf463","article-title":"XPC-RAD23B enhances UV-DDB binding to DNA to facilitate lesion search in nucleotide excision repair","volume":"53","author":"An","year":"2025","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jtherbio.2026.104579_bib8","doi-asserted-by":"crossref","first-page":"460","DOI":"10.3390\/s26020460","article-title":"Dynamic infrared thermographic evaluation of facial thermal response during face mask wearing","volume":"26","author":"Angelova","year":"2026","journal-title":"Sensors"},{"key":"10.1016\/j.jtherbio.2026.104579_bib9","doi-asserted-by":"crossref","first-page":"3974","DOI":"10.3390\/ijms22083974","article-title":"Inflammatory molecules associated with ultraviolet radiation-mediated skin aging","volume":"22","author":"Ansary","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jtherbio.2026.104579_bib10","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1113\/EP093011","article-title":"Sweat evaporation in humans: a molecular and thermodynamic perspective","volume":"111","author":"Ashworth","year":"2026","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.vibspec.2021.103250","article-title":"The problem of manifestation of tertiary structure in the vibrational spectra of proteins","volume":"114","author":"Balakhnina","year":"2021","journal-title":"Vib. Spectrosc."},{"key":"10.1016\/j.jtherbio.2026.104579_bib12","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1111\/php.13470","article-title":"Photosensitization reactions of biomolecules: definition, targets and mechanisms","volume":"97","author":"Baptista","year":"2021","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib13","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1017\/S0033583502003815","article-title":"What vibrations tell us about proteins","volume":"35","author":"Barth","year":"2002","journal-title":"Q. Rev. Biophys."},{"key":"10.1016\/j.jtherbio.2026.104579_bib14","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2023.1131683","article-title":"Involvement of heat shock proteins HSP70 in the mechanisms of endogenous neuroprotection: the prospect of using HSP70 modulators","volume":"17","author":"Belenichev","year":"2023","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.jtherbio.2026.104579_bib15","doi-asserted-by":"crossref","first-page":"6343","DOI":"10.1039\/C5AN00979K","article-title":"Evaluation of UV radiation-induced toxicity and biophysical changes in various skin cells with photo-shielding molecules","volume":"140","author":"Bennet","year":"2015","journal-title":"The Analyst"},{"key":"10.1016\/j.jtherbio.2026.104579_bib16","first-page":"3079","article-title":"Wavelength dependence of ultraviolet radiation-induced DNA damage as determined by laser irradiation suggests that cyclobutane pyrimidine dimers are the principal DNA lesions produced by terrestrial sunlight","volume":"25","author":"Besaratinia","year":"2011","journal-title":"FASEB J. Off. Publ. Fed. Am. Soc. Exp. Biol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.jphotobiol.2024.113070","article-title":"Comparison of the mechanisms of DNA damage following photoexcitation and chemiexcitation","volume":"262","author":"Boaro","year":"2025","journal-title":"J. Photochem. Photobiol., B"},{"key":"10.1016\/j.jtherbio.2026.104579_bib18","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/8549532","article-title":"Xeroderma Pigmentosum: a genetic condition skin cancer Correlated-A systematic review","author":"Brambullo","year":"2022","journal-title":"BioMed Res. Int."},{"key":"10.1016\/j.jtherbio.2026.104579_bib19","doi-asserted-by":"crossref","first-page":"920","DOI":"10.3389\/fphar.2018.00920","article-title":"Targeting mitochondrial oxidative stress to mitigate UV-Induced skin damage","volume":"9","author":"Brand","year":"2018","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib20","first-page":"1816","article-title":"Formation of UV-induced DNA damage contributing to skin cancer development","volume":"17","author":"Cadet","year":"2018","journal-title":"Photochem. Photobiol. Sci. Off. J. Eur. Photochem. Assoc. Eur. Soc. Photobiol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.jphotobiol.2024.113088","article-title":"Novel peptide inhibitor of matrix Metalloproteinases-1 from pufferfish skin collagen hydrolysates and its potential photoprotective activity via the MAPK\/AP-1 signaling pathway","volume":"262","author":"Chen","year":"2025","journal-title":"J. Photochem. Photobiol., B"},{"key":"10.1016\/j.jtherbio.2026.104579_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2024.108581","article-title":"Exposure to ambient temperature and heat index in relation to DNA methylation age: a population-based study in Taiwan","volume":"186","author":"Chiu","year":"2024","journal-title":"Environ. Int."},{"key":"10.1016\/j.jtherbio.2026.104579_bib23","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1038\/jidsymp.2009.7","article-title":"Effects of infrared radiation and heat on human skin aging in vivo","volume":"14","author":"Cho","year":"2009","journal-title":"J. Invest. Dermatol. Symp. Proc."},{"key":"10.1016\/j.jtherbio.2026.104579_bib24","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.adr0616","article-title":"Ambient outdoor heat and accelerated epigenetic aging among older adults in the US","volume":"11","author":"Choi","year":"2025","journal-title":"Sci. Adv."},{"key":"10.1016\/j.jtherbio.2026.104579_bib25","doi-asserted-by":"crossref","DOI":"10.1038\/srep33112","article-title":"Temperature-sensitive gating of TRPV1 channel as probed by atomistic simulations of its trans- and juxtamembrane domains","volume":"6","author":"Chugunov","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jtherbio.2026.104579_bib26","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0050733","article-title":"UV-Light exposure of insulin: pharmaceutical implications upon covalent insulin dityrosine dimerization and disulphide bond photolysis","volume":"7","author":"Correia","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jtherbio.2026.104579_bib27","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/978-3-319-56017-5_2","article-title":"Ultraviolet light induced generation of reactive oxygen species","volume":"996","author":"de Jager","year":"2017","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib28","doi-asserted-by":"crossref","first-page":"662","DOI":"10.3390\/antiox14060662","article-title":"MAPK signaling in the interplay between oxidative stress and autophagy","volume":"14","author":"Desideri","year":"2025","journal-title":"Antioxidants"},{"key":"10.1016\/j.jtherbio.2026.104579_bib29","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.3390\/antiox14091140","article-title":"Sheng mai san mitigates heat stress-induced myocardial injury by coordinated regulation of the Keap1-Nrf2-HO-1 and Stub 1-HSF1 signaling pathways","volume":"14","author":"Dong","year":"2025","journal-title":"Antioxidants"},{"key":"10.1016\/j.jtherbio.2026.104579_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e37019","article-title":"Astragaloside IV ameliorates pressure overload-induced heart failure by enhancing angiogenesis through HSF1\/VEGF pathway","volume":"10","author":"Du","year":"2024","journal-title":"Heliyon"},{"key":"10.1016\/j.jtherbio.2026.104579_bib31","doi-asserted-by":"crossref","first-page":"3847","DOI":"10.1111\/jocd.16558","article-title":"Matrix metalloproteinases on skin photoaging","volume":"23","author":"Feng","year":"2024","journal-title":"J. Cosmet. Dermatol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib32","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1038\/jid.1966.15","article-title":"Erythema ab igne: a histopathological study","volume":"46","author":"Finlayson","year":"1966","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib33","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.3390\/cells12081189","article-title":"A preliminary study of mild heat stress on inflammasome activation in murine macrophages","volume":"12","author":"Foster","year":"2023","journal-title":"Cells"},{"key":"10.1016\/j.jtherbio.2026.104579_bib34","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1134\/S0026893324010047","article-title":"[Photochemical Processes of Cell DNA Damage by UV Radiation of Various Wavelengths: Biological Consequences]","volume":"58","author":"Fraikin","year":"2024","journal-title":"Mol. Biol. (Mosk.)"},{"key":"10.1016\/j.jtherbio.2026.104579_bib35","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s12016-020-08824-3","article-title":"New insights on the role of TRP channels in calcium signalling and immunomodulation: review of pathways and implications for clinical practice","volume":"60","author":"Froghi","year":"2021","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib36","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.3390\/ijms23042040","article-title":"The thermal stability of the collagen triple helix is tuned according to the environmental temperature","volume":"23","author":"Fujii","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jtherbio.2026.104579_bib37","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1007\/s00294-021-01191-2","article-title":"Reversible protein aggregation as cytoprotective mechanism against heat stress","volume":"67","author":"Gallardo","year":"2021","journal-title":"Curr. Genet."},{"key":"10.1016\/j.jtherbio.2026.104579_bib38","doi-asserted-by":"crossref","first-page":"e236","DOI":"10.1097\/PEC.0000000000001460","article-title":"Erythema Ab igne in an adolescent with chronic pain: an alarming cutaneous eruption from heat exposure","volume":"36","author":"Gmuca","year":"2020","journal-title":"Pediatr. Emerg. Care"},{"key":"10.1016\/j.jtherbio.2026.104579_bib39","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1007\/s13238-017-0395-5","article-title":"TRPV1 and TRPA1 in cutaneous neurogenic and chronic inflammation: pro-inflammatory response induced by their activation and their sensitization","volume":"8","author":"Gouin","year":"2017","journal-title":"Protein Cell"},{"key":"10.1016\/j.jtherbio.2026.104579_bib40","first-page":"4602","article-title":"Epidermal keratinocyte polarity and motility require Ca2+ influx through TRPV1","volume":"126","author":"Graham","year":"2013","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.jtherbio.2026.104579_bib41","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1038\/nn.2552","article-title":"Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain","volume":"13","author":"Grandl","year":"2010","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.jtherbio.2026.104579_bib42","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1007\/s00403-014-1461-y","article-title":"Additive effect of heat on the UVB-induced tyrosinase activation and melanogenesis via ERK\/p38\/MITF pathway in human epidermal melanocytes","volume":"306","author":"Gu","year":"2014","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.jtherbio.2026.104579_bib43","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/j.tplants.2022.03.006","article-title":"How do humans and plants feel the heat?","volume":"27","author":"Guihur","year":"2022","journal-title":"Trends Plant Sci., Special issue: Climate change and sustainability I"},{"key":"10.1016\/j.jtherbio.2026.104579_bib44","article-title":"Erythema Ab igne: a rare presentation of toasted skin syndrome with the use of a space heater","volume":"13","author":"Haleem","year":"2021","journal-title":"Cureus"},{"key":"10.1016\/j.jtherbio.2026.104579_bib45","doi-asserted-by":"crossref","first-page":"E33","DOI":"10.12788\/cutis.0771","article-title":"Erythema Ab igne: a clinical review","volume":"111","author":"Harview","year":"2023","journal-title":"Cutis"},{"key":"10.1016\/j.jtherbio.2026.104579_bib46","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.bbrc.2016.06.106","article-title":"Nuclear DNA damage-triggered NLRP3 inflammasome activation promotes UVB-induced inflammatory responses in human keratinocytes","volume":"477","author":"Hasegawa","year":"2016","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jtherbio.2026.104579_bib48","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.ado3498","article-title":"Human heat sensation: a randomized crossover trial","volume":"10","author":"Heber","year":"2024","journal-title":"Sci. Adv."},{"key":"10.1016\/j.jtherbio.2026.104579_bib49","doi-asserted-by":"crossref","first-page":"4483","DOI":"10.3390\/ijms25084483","article-title":"Unlocking the power of light on the skin: a comprehensive review on photobiomodulation","volume":"25","author":"Hern\u00e1ndez-Bule","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jtherbio.2026.104579_bib50","doi-asserted-by":"crossref","first-page":"3800","DOI":"10.1093\/emboj\/20.14.3800","article-title":"Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1","volume":"20","author":"Holmberg","year":"2001","journal-title":"EMBO J."},{"key":"10.1016\/j.jtherbio.2026.104579_bib51","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1038\/jid.2010.79","article-title":"The other end of the rainbow: infrared and skin","volume":"130","author":"Holzer","year":"2010","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib52","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/s40560-025-00832-9","article-title":"Heat stress-induced mitochondrial damage and its impact on leukocyte function","volume":"13","author":"Iba","year":"2025","journal-title":"J. Intensiv. Care"},{"key":"10.1016\/j.jtherbio.2026.104579_bib53","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1111\/jpn.13966","article-title":"Protective effect of chlorogenic acid on liver injury in heat-stressed meat rabbits","volume":"108","author":"Ji","year":"2024","journal-title":"J. Anim. Physiol. Anim. Nutr."},{"key":"10.1016\/j.jtherbio.2026.104579_bib54","doi-asserted-by":"crossref","first-page":"32936","DOI":"10.1021\/acsomega.2c04424","article-title":"UVA radiation, DNA damage, and Melanoma","volume":"7","author":"Jin","year":"2022","journal-title":"ACS Omega"},{"key":"10.1016\/j.jtherbio.2026.104579_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.conb.2022.102591","article-title":"TRP channels in thermosensation","volume":"75","author":"Kashio","year":"2022","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib56","first-page":"6304","article-title":"Participation of p53 protein in the cellular response to DNA damage","volume":"51","author":"Kastan","year":"1991","journal-title":"Cancer Res."},{"key":"10.1016\/j.jtherbio.2026.104579_bib57","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.1755","article-title":"HSP47 in human diseases: navigating pathophysiology, diagnosis and therapy","volume":"14","author":"Khan","year":"2024","journal-title":"Clin. Transl. Med."},{"key":"10.1016\/j.jtherbio.2026.104579_bib58","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s41116-025-00040-5","article-title":"Solar irradiance measurements","volume":"22","author":"Kopp","year":"2025","journal-title":"Living Rev. Sol. Phys."},{"key":"10.1016\/j.jtherbio.2026.104579_bib59","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.jdermsci.2013.07.015","article-title":"Solar-simulated radiation and heat treatment induced metalloproteinase-1 expression in cultured dermal fibroblasts via distinct pathways: implications on reduction of sun-associated aging","volume":"72","author":"Lan","year":"2013","journal-title":"J. Dermatol. Sci."},{"key":"10.1016\/j.jtherbio.2026.104579_bib60","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1002\/jcp.21729","article-title":"A novel role for the TRPV1 channel in UV-induced matrix metalloproteinase (MMP)-1 expression in HaCaT cells","volume":"219","author":"Lee","year":"2009","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib61","doi-asserted-by":"crossref","DOI":"10.1002\/bies.202400047","article-title":"Unlocking the therapeutic potential of TRPV3: insights into thermosensation, channel modulation, and skin homeostasis involving TRPV3","volume":"46","author":"Lei","year":"2024","journal-title":"BioEssays News Rev. Mol. Cell. Dev. Biol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib62","doi-asserted-by":"crossref","first-page":"673","DOI":"10.3390\/e20090673","article-title":"Molecules and the eigenstate thermalization hypothesis","volume":"20","author":"Leitner","year":"2018","journal-title":"Entropy"},{"key":"10.1016\/j.jtherbio.2026.104579_bib63","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1080\/02656730310001637334","article-title":"Role of nuclear protein denaturation and aggregation in thermal radiosensitization","volume":"20","author":"Lepock","year":"2004","journal-title":"Int. J. Hyperth. Off. J. Eur. Soc. Hyperthermic Oncol. North Am. Hyperth. Group"},{"key":"10.1016\/j.jtherbio.2026.104579_bib64","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/st9.0000000000000062","article-title":"Promoting international acceptance of clinical studies about traditional Chinese medicine interventions","volume":"3","author":"Li","year":"2025","journal-title":"Sci. Tradit. Chin. Med."},{"key":"10.1016\/j.jtherbio.2026.104579_bib65","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1038\/sj.jid.5700880","article-title":"Transient receptor potential vanilloid-1 mediates heat-shock-induced matrix metalloproteinase-1 expression in human epidermal keratinocytes","volume":"127","author":"Li","year":"2007","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib66","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1007\/s00223-018-0425-1","article-title":"Glycyrrhizin suppresses RANKL-Induced osteoclastogenesis and oxidative stress through inhibiting NF-\u03baB and MAPK and activating AMPK\/Nrf2","volume":"103","author":"Li","year":"2018","journal-title":"Calcif. Tissue Int."},{"key":"10.1016\/j.jtherbio.2026.104579_bib67","doi-asserted-by":"crossref","first-page":"25661","DOI":"10.1039\/D0CP04557H","article-title":"Experimental and theoretical studies on thymine photodimerization mediated by oxidatively generated DNA lesions and epigenetic intermediates","volume":"22","author":"Lineros-Rosa","year":"2020","journal-title":"Phys. Chem. Chem. Phys. PCCP"},{"key":"10.1016\/j.jtherbio.2026.104579_bib68","doi-asserted-by":"crossref","first-page":"5681","DOI":"10.1039\/D4SC00595C","article-title":"A near-IR ratiometric fluorescent probe for the precise tracking of senescence: a multidimensional sensing assay of biomarkers in cell senescence pathways","volume":"15","author":"Liu","year":"2024","journal-title":"Chem. Sci."},{"key":"10.1016\/j.jtherbio.2026.104579_bib69","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1097\/st9.0000000000000073","article-title":"Network pharmacology: advancing the application of large language models in traditional Chinese medicine research","volume":"3","author":"Liu","year":"2025","journal-title":"Sci. Tradit. Chin. Med."},{"key":"10.1016\/j.jtherbio.2026.104579_bib70","article-title":"Interplay between MAPK signaling pathway and autophagy in skin aging: mechanistic insights and therapeutic implications","volume":"13","author":"Liu","year":"2025","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib71","doi-asserted-by":"crossref","first-page":"3466","DOI":"10.1021\/acs.chemrev.9b00449","article-title":"Infrared difference spectroscopy of proteins: from bands to bonds","volume":"120","author":"Lorenz-Fonfria","year":"2020","journal-title":"Chem. Rev."},{"key":"10.1016\/j.jtherbio.2026.104579_bib72","article-title":"Guarding skin under PPE: mechanistic insights and technological innovations","volume":"29","author":"Lu","year":"2023","journal-title":"Skin Res. Technol. Off. J. Int. Soc. Bioeng. Skin ISBS Int. Soc. Digit. Imaging Skin ISDIS Int. Soc. Skin Imaging"},{"key":"10.1016\/j.jtherbio.2026.104579_bib73","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1080\/23328940.2021.1983354","article-title":"A molecular perspective on identifying TRPV1 thermosensitive regions and disentangling polymodal activation","volume":"10","author":"Luu","year":"2023","journal-title":"Temperature (Austin)"},{"key":"10.1016\/j.jtherbio.2026.104579_bib74","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1038\/s41423-025-01310-w","article-title":"NF-\u03baB in inflammation and cancer","volume":"22","author":"Mao","year":"2025","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib75","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/php.12533","article-title":"UV-induced DNA damage: the role of electronic excited States","volume":"92","author":"Markovitsi","year":"2016","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib76","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1111\/j.1365-2133.2004.06173.x","article-title":"Photostability of sunscreen products influences the efficiency of protection with regard to UV-induced genotoxic or photoageing-related endpoints","volume":"151","author":"Marrot","year":"2004","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib77","doi-asserted-by":"crossref","first-page":"d765","DOI":"10.2741\/matsumur","article-title":"Molecular mechanisms of photocarcinogenesis","volume":"7","author":"Matsumura","year":"2002","journal-title":"Front. Biosci. J. Virtual Libr."},{"key":"10.1016\/j.jtherbio.2026.104579_bib78","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejcb.2020.151108","article-title":"Aging of the cells: insight into cellular senescence and detection methods","volume":"99","author":"Mohamad Kamal","year":"2020","journal-title":"Eur. J. Cell Biol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib79","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2023.1267409","article-title":"Damaging effects of UVA, blue light, and infrared radiation: in vitro assessment on a reconstructed full-thickness human skin","volume":"10","author":"Montero","year":"2023","journal-title":"Front. Med."},{"key":"10.1016\/j.jtherbio.2026.104579_bib80","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2300305120","article-title":"A suicidal mechanism for the exquisite temperature sensitivity of TRPV1","volume":"120","author":"Mugo","year":"2023","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jtherbio.2026.104579_bib81","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1113\/JP280518","article-title":"Exertional heat stroke leads to concurrent long-term epigenetic memory, immunosuppression and altered heat shock response in female mice","volume":"599","author":"Murray","year":"2021","journal-title":"J. Physiol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib82","doi-asserted-by":"crossref","first-page":"144","DOI":"10.3390\/cosmetics12040144","article-title":"Decoding skin aging: a review of mechanisms, markers, and modern therapies","volume":"12","author":"Naharro-Rodriguez","year":"2025","journal-title":"Cosmetics"},{"key":"10.1016\/j.jtherbio.2026.104579_bib83","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2023.108109","article-title":"Associations between medium- and long-term exposure to air temperature and epigenetic age acceleration","volume":"178","author":"Ni","year":"2023","journal-title":"Environ. Int."},{"key":"10.1016\/j.jtherbio.2026.104579_bib84","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1146\/annurev-biochem-052621-091205","article-title":"Transcription-coupled nucleotide excision repair and the transcriptional response to UV-Induced DNA damage","volume":"92","author":"Nieto Moreno","year":"2023","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.jtherbio.2026.104579_bib85","doi-asserted-by":"crossref","first-page":"8684","DOI":"10.3390\/ijms22168684","article-title":"Role of nuclear factor of activated T cells (NFAT) pathway in regulating autophagy and inflammation in retinal pigment epithelial cells","volume":"22","author":"Pan","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jtherbio.2026.104579_bib86","doi-asserted-by":"crossref","first-page":"195","DOI":"10.3389\/fimmu.2020.00195","article-title":"The role of Calcium-Calcineurin-NFAT signaling pathway in health and autoimmune diseases","volume":"11","author":"Park","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib87","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1001\/jamadermatol.2017.2021","article-title":"The evolving nomenclature of erythema Ab igne-redness from fire","volume":"153","author":"Patel","year":"2017","journal-title":"JAMA Dermatol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib88","doi-asserted-by":"crossref","first-page":"88","DOI":"10.3390\/cells15010088","article-title":"Photobiomodulation activates coordinated signaling networks to modulate inflammation, adaptive stress, and tissue healing via redox-mediated NF\u03baB-TGF-\u03b21-ATF-4 axis","volume":"15","author":"Ponnusamy","year":"2026","journal-title":"Cells"},{"key":"10.1016\/j.jtherbio.2026.104579_bib89","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1111\/php.12687","article-title":"Crosstalk among UV-Induced inflammatory mediators, DNA damage and epigenetic regulators facilitates suppression of the immune system","volume":"93","author":"Prasad","year":"2017","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib90","series-title":"Sunlight, Vitamin D and Skin Cancer, Advances in Experimental Medicine and Biology","first-page":"162","article-title":"UV damage and DNA repair in malignant melanoma and nonmelanoma skin cancer","author":"Rass","year":"2008"},{"key":"10.1016\/j.jtherbio.2026.104579_bib91","doi-asserted-by":"crossref","DOI":"10.4061\/2010\/592980","article-title":"Molecular mechanisms of ultraviolet radiation-induced DNA damage and repair","volume":"2010","author":"Rastogi","year":"2010","journal-title":"J. Nucleic Acids"},{"key":"10.1016\/j.jtherbio.2026.104579_bib92","doi-asserted-by":"crossref","first-page":"4777","DOI":"10.1021\/acs.biochem.6b00420","article-title":"Photooxidation of tryptophan and tyrosine residues in human serum albumin sensitized by pterin: a model for globular protein photodamage in skin","volume":"55","author":"Reid","year":"2016","journal-title":"Biochemistry"},{"key":"10.1016\/j.jtherbio.2026.104579_bib93","first-page":"689","article-title":"Resveratrol inhibits NF-kB signaling through suppression of p65 and IkappaB kinase activities","volume":"68","author":"Ren","year":"2013","journal-title":"Pharm. Times"},{"key":"10.1016\/j.jtherbio.2026.104579_bib94","doi-asserted-by":"crossref","first-page":"iii","DOI":"10.2144\/000113198","article-title":"Functional assessment of temperature-gated ion-channel activity using a real-time PCR machine","volume":"47","author":"Reubish","year":"2009","journal-title":"Biotechniques"},{"key":"10.1016\/j.jtherbio.2026.104579_bib95","doi-asserted-by":"crossref","first-page":"35356","DOI":"10.1021\/acsomega.4c00875","article-title":"The photophysics and photochemistry of phenylalanine, tyrosine, and tryptophan: a CASSCF\/CASPT2 study","volume":"9","author":"Salmahaminati","year":"2024","journal-title":"ACS Omega"},{"key":"10.1016\/j.jtherbio.2026.104579_bib96","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1007\/s12551-025-01275-0","article-title":"Impact of ecological UV radiation on the photochemistry of nuclear DNA","volume":"17","author":"S\u00e1nchez","year":"2025","journal-title":"Biophys. Rev."},{"key":"10.1016\/j.jtherbio.2026.104579_bib97","doi-asserted-by":"crossref","first-page":"835","DOI":"10.3390\/molecules25040835","article-title":"Ginseng extract ameliorates the negative physiological effects of heat stress by supporting heat shock response and improving intestinal barrier integrity: evidence from studies with heat-stressed Caco-2 cells, C. elegans and growing broilers","volume":"25","author":"Sandner","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.jtherbio.2026.104579_bib98","doi-asserted-by":"crossref","first-page":"4624","DOI":"10.3390\/ijerph17134624","article-title":"Facial skin temperature and discomfort when wearing protective face masks: thermal infrared imaging evaluation and hands moving the mask","volume":"17","author":"Scarano","year":"2020","journal-title":"Int. J. Environ. Res. Public. Health"},{"key":"10.1016\/j.jtherbio.2026.104579_bib99","doi-asserted-by":"crossref","first-page":"4357","DOI":"10.3390\/molecules24234357","article-title":"Thiyl radical reactions in the chemical degradation of pharmaceutical proteins","volume":"24","author":"Sch\u00f6neich","year":"2019","journal-title":"Molecules"},{"key":"10.1016\/j.jtherbio.2026.104579_bib100","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.freeradbiomed.2017.01.029","article-title":"Sunlight damage to cellular DNA: focus on oxidatively generated lesions","volume":"107","author":"Schuch","year":"2017","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.jtherbio.2026.104579_bib101","doi-asserted-by":"crossref","DOI":"10.3390\/ijms251910439","article-title":"pH-Responsive collagen hydrogels prepared by UV irradiation in the presence of riboflavin","volume":"25","author":"Setoyama","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jtherbio.2026.104579_bib102","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1097\/st9.0000000000000089","article-title":"Polyphenolic compounds: alleviating osteoarthritis by regulating inflammation and oxidative stress","volume":"3","author":"Sheng","year":"2025","journal-title":"Sci. Tradit. Chin. Med."},{"key":"10.1016\/j.jtherbio.2026.104579_bib103","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.3390\/ijms20092126","article-title":"Molecular mechanisms of dermal aging and antiaging approaches","volume":"20","author":"Shin","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jtherbio.2026.104579_bib104","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.mad.2012.01.006","article-title":"Chronic heat treatment causes skin wrinkle formation and oxidative damage in hairless mice","volume":"133","author":"Shin","year":"2012","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.jtherbio.2026.104579_bib105","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/B978-0-12-405881-1.00002-1","article-title":"Reactive oxygen species in the activation of MAP kinases","volume":"528","author":"Son","year":"2013","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib106","doi-asserted-by":"crossref","DOI":"10.3389\/fmolb.2025.1564364","article-title":"Heat shock proteins in hypothermia: a review","volume":"12","author":"Song","year":"2025","journal-title":"Front. Mol. Biosci."},{"key":"10.1016\/j.jtherbio.2026.104579_bib107","doi-asserted-by":"crossref","first-page":"774","DOI":"10.3390\/biology14070774","article-title":"HSP70-Mediated autophagy-apoptosis-inflammation network and neuroprotection induced by heat acclimatization","volume":"14","author":"Su","year":"2025","journal-title":"Biology"},{"key":"10.1016\/j.jtherbio.2026.104579_bib108","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.jep.2010.03.039","article-title":"Anti-nociceptive mechanism of baicalin involved in intervention of TRPV1 in DRG neurons in vitro","volume":"129","author":"Sui","year":"2010","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib109","doi-asserted-by":"crossref","first-page":"394","DOI":"10.3390\/biology13060394","article-title":"Harnessing mitochondrial stress for health and disease: opportunities and challenges","volume":"13","author":"Sun","year":"2024","journal-title":"Biology"},{"key":"10.1016\/j.jtherbio.2026.104579_bib110","doi-asserted-by":"crossref","first-page":"7902","DOI":"10.3390\/molecules28237902","article-title":"Thermodynamic and vibrational aspects of peptide bond hydrolysis and their potential relationship to the harmfulness of infrared radiation","volume":"28","author":"Tsioptsias","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.jtherbio.2026.104579_bib111","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2025.1675619","article-title":"Photobiomodulation in fibroblasts: from light to healing through molecular pathways, omics and artificial intelligence","volume":"13","author":"Ucci","year":"2025","journal-title":"Front. Bioeng. Biotechnol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib112","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2025.1592751","article-title":"Targeting inflammatory macrophages with hyaluronan tetrasaccharide: effects on fibroblast collagen degradation and synthesis","volume":"16","author":"Uno","year":"2025","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib113","doi-asserted-by":"crossref","first-page":"142","DOI":"10.36849\/JDD.8102","article-title":"Sunscreens: mechanisms and safety in depth","volume":"24","author":"V Cha\u0142upczak","year":"2025","journal-title":"J. Drugs Dermatol. JDD"},{"key":"10.1016\/j.jtherbio.2026.104579_bib114","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.clindermatol.2016.05.022","article-title":"The dark side of the light: mechanisms of photocarcinogenesis","volume":"34","author":"Valejo Coelho","year":"2016","journal-title":"Clin. Dermatol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib115","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1111\/j.1476-5381.2011.01601.x","article-title":"The thermo-TRP ion channel family: properties and therapeutic implications","volume":"165","author":"Vay","year":"2012","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib116","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.3390\/biomedicines9111564","article-title":"UV radiation in DNA damage and repair involving DNA-photolyases and cryptochromes","volume":"9","author":"Vechtomova","year":"2021","journal-title":"Biomedicines"},{"key":"10.1016\/j.jtherbio.2026.104579_bib117","doi-asserted-by":"crossref","first-page":"3450","DOI":"10.1091\/mbc.e11-12-1009","article-title":"Dual effect of heat shock on DNA replication and genome integrity","volume":"23","author":"Velichko","year":"2012","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.jtherbio.2026.104579_bib118","doi-asserted-by":"crossref","first-page":"6309","DOI":"10.1093\/nar\/gkv573","article-title":"Mechanism of heat stress-induced cellular senescence elucidates the exclusive vulnerability of early S-phase cells to mild genotoxic stress","volume":"43","author":"Velichko","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jtherbio.2026.104579_bib119","doi-asserted-by":"crossref","first-page":"534","DOI":"10.3390\/cells15060534","article-title":"TRPC6-Mediated Ca2+ influx activates MAPK and NF\u03baB signaling and elicits pro-inflammatory and catabolic responses in human intervertebral disc cells","volume":"15","author":"Venkatachala Babu","year":"2026","journal-title":"Cells"},{"key":"10.1016\/j.jtherbio.2026.104579_bib120","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1021\/envhealth.4c00007","article-title":"Extreme heat exposure induced acute kidney injury through NLRP3 inflammasome activation in mice","volume":"2","author":"Wang","year":"2024","journal-title":"Environ. Health"},{"key":"10.1016\/j.jtherbio.2026.104579_bib121","article-title":"Research progress on traditional Chinese medicine compounds in autoimmune-related skin diseases","volume":"16","author":"Wang","year":"2025","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib122","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1002\/vms3.318","article-title":"Baicalin prevents the up-regulation of TRPV1 in dorsal root ganglion and attenuates chronic neuropathic pain","volume":"6","author":"Wang","year":"2020","journal-title":"Vet. Med. Sci."},{"key":"10.1016\/j.jtherbio.2026.104579_bib123","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1152\/jn.00638.2011","article-title":"Mitochondrial dysfunction induced by heat stress in cultured rat CNS neurons","volume":"108","author":"White","year":"2012","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib124","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2022.112686","article-title":"Liposome-templated gold nanoparticles for precisely temperature-controlled photothermal therapy based on heat shock protein expression","volume":"217","author":"Xia","year":"2022","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"10.1016\/j.jtherbio.2026.104579_bib125","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2023.1037925","article-title":"TRPV1: a promising therapeutic target for skin aging and inflammatory skin diseases","volume":"14","author":"Xiao","year":"2023","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib126","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1093\/nar\/gkq855","article-title":"Photosensitized [2 + 2] cycloaddition of N-acetylated cytosine affords stereoselective formation of cyclobutane pyrimidine dimer","volume":"39","author":"Yamamoto","year":"2011","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jtherbio.2026.104579_bib127","doi-asserted-by":"crossref","first-page":"554","DOI":"10.3390\/ijms21020554","article-title":"Riboflavin plays a pivotal role in the UVA-induced cytotoxicity of fibroblasts as a key molecule in the production of H2O2 by UVA radiation in collaboration with amino acids and vitamins","volume":"21","author":"Yoshimoto","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jtherbio.2026.104579_bib128","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1093\/jn\/nxaa201","article-title":"Curcumin ameliorates heat-induced injury through NADPH oxidase-dependent redox signaling and mitochondrial preservation in C2C12 myoblasts and mouse skeletal muscle","volume":"150","author":"Yu","year":"2020","journal-title":"J. Nutr."},{"key":"10.1016\/j.jtherbio.2026.104579_bib129","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s43556-024-00209-8","article-title":"Ultraviolet (UV) radiation: a double-edged sword in cancer development and therapy","volume":"5","author":"Yu","year":"2024","journal-title":"Mol. Biomed."},{"key":"10.1016\/j.jtherbio.2026.104579_bib130","doi-asserted-by":"crossref","DOI":"10.1111\/exd.70114","article-title":"Role of mitochondrial dysfunction in UV-Induced photoaging and skin cancers","volume":"34","author":"Yuan","year":"2025","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib131","doi-asserted-by":"crossref","first-page":"950","DOI":"10.3390\/life12070950","article-title":"Melatonin prevents UVB-Induced skin photoaging by inhibiting oxidative damage and MMP expression through JNK\/AP-1 signaling pathway in human dermal fibroblasts","volume":"12","author":"Yuksel Egrilmez","year":"2022","journal-title":"Life"},{"key":"10.1016\/j.jtherbio.2026.104579_bib132","doi-asserted-by":"crossref","first-page":"3351","DOI":"10.7150\/ijbs.110447","article-title":"HSF1 activation mechanisms, disease roles, and small molecule therapeutics","volume":"21","author":"Zhang","year":"2025","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.jtherbio.2026.104579_bib133","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1007\/s10103-024-04018-x","article-title":"A study of the biological effects of low-level light","volume":"39","author":"Zhang","year":"2024","journal-title":"Lasers Med. Sci."},{"key":"10.1016\/j.jtherbio.2026.104579_bib134","article-title":"Selected traditional Chinese herbal medicines for the treatment of atopic dermatitis - research progress on the effect and mechanism of actions","volume":"16","author":"Zhang","year":"2025","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib135","article-title":"Heat promotes melanogenesis by increasing the paracrine effects in keratinocytes via the TRPV3\/Ca2+\/Hh signaling pathway","volume":"26","author":"Zhang","year":"2023","journal-title":"iScience"},{"key":"10.1016\/j.jtherbio.2026.104579_bib136","article-title":"Sheng Mai San ameliorated heat stress-induced liver injury via regulating energy metabolism and AMPK\/Drp1-dependent autophagy process","volume":"97","author":"Zhang","year":"2022","journal-title":"Phytomedicine Int. J. Phytother. Phytopharm."},{"key":"10.1016\/j.jtherbio.2026.104579_bib137","doi-asserted-by":"crossref","first-page":"807","DOI":"10.3724\/abbs.2022054","article-title":"Nucleotide excision repair: a versatile and smart toolkit","volume":"54","author":"Zhang","year":"2022","journal-title":"Acta Biochim. Biophys. Sin."},{"key":"10.1016\/j.jtherbio.2026.104579_bib138","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1186\/s12986-025-01047-3","article-title":"From molecular mechanisms to translational applications: a parallel assessment of green and black tea modulation of oxidative stress","volume":"22","author":"Zhao","year":"2025","journal-title":"Nutr. Metab."},{"key":"10.1016\/j.jtherbio.2026.104579_bib139","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1080\/23328940.2019.1578634","article-title":"Heat activation mechanism of TRPV1: new insights from molecular dynamics simulation","volume":"6","author":"Zheng","year":"2019","journal-title":"Temperature (Austin)"},{"key":"10.1016\/j.jtherbio.2026.104579_bib140","article-title":"Role of autophagy in skin photoaging: a narrative review","volume":"103","author":"Zhong","year":"2024","journal-title":"Medicine (Baltim.)"},{"key":"10.1016\/j.jtherbio.2026.104579_bib141","doi-asserted-by":"crossref","first-page":"9313","DOI":"10.1038\/s41467-025-64380-4","article-title":"And-1 coordinates with polymerase \u03b4 to regulate nucleotide excision repair and UVB-induced skin tumorigenesis","volume":"16","author":"Zhou","year":"2025","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jtherbio.2026.104579_bib142","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/8798861","article-title":"Arbutin inhibited heat stress-induced apoptosis and promoted proliferation and migration of heat-injured dermal fibroblasts and keratinocytes by activating PI3K\/AKT signaling pathway","volume":"2022","author":"Zhu","year":"2022","journal-title":"Evid. Based Complement. Alternat. Med."},{"key":"10.1016\/j.jtherbio.2026.104579_bib143","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdsct.2025.100101","article-title":"Key targets and pathways in skin photoaging: a comprehensive review","volume":"2","author":"Zhu","year":"2025","journal-title":"J. Dermatol. Sci. Cosmet. Technol."},{"key":"10.1016\/j.jtherbio.2026.104579_bib144","doi-asserted-by":"crossref","DOI":"10.1111\/cbdd.14390","article-title":"Naringin acts as a TRPV1 antagonist to attenuate UVB-induced senescence and damage in HaCaT cells","volume":"103","author":"Zhu","year":"2024","journal-title":"Chem. Biol. Drug Des."}],"container-title":["Journal of Thermal Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306456526002123?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306456526002123?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T14:41:17Z","timestamp":1792852877000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306456526002123"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":142,"alternative-id":["S0306456526002123"],"URL":"https:\/\/doi.org\/10.1016\/j.jtherbio.2026.104579","relation":{},"ISSN":["0306-4565"],"issn-type":[{"value":"0306-4565","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Skin thermal damage as an independent pathophysiological entity: Molecular mechanisms distinct from photoaging and implications for systemic conditioning strategies","name":"articletitle","label":"Article Title"},{"value":"Journal of Thermal Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtherbio.2026.104579","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"104579"}}