{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:32:43Z","timestamp":1790775163982,"version":"4.1.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["jto.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Thoracic Oncology"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.jtho.2021.07.004","type":"journal-article","created":{"date-parts":[[2021,7,10]],"date-time":"2021-07-10T19:17:56Z","timestamp":1625944676000},"page":"1936-1945","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["The International Thymic Malignancy Interest Group Classification of Thymoma Recurrence: Survival Analysis and Perspectives"],"prefix":"10.1016","volume":"16","author":[{"given":"Marco","family":"Chiappetta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Lococo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edoardo","family":"Zanfrini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rossana","family":"Moroni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vittorio","family":"Aprile","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Guerrera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dania","family":"Nachira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Teresa","family":"Congedo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcello Carlo","family":"Ambrogi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stylianos","family":"Korasidis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Lucchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pier Luigi","family":"Filosso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Ruffini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella","family":"Sperduti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Meacci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Margaritora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"suppl 4","key":"10.1016\/j.jtho.2021.07.004_bib1","doi-asserted-by":"crossref","first-page":"S318","DOI":"10.1097\/JTO.0b013e3181f20dab","article-title":"Evaluation and treatment of stage I and II thymoma","volume":"5","author":"Detterbeck","year":"2010","journal-title":"J\u00a0Thorac Oncol"},{"key":"10.1016\/j.jtho.2021.07.004_bib2","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1186\/s13019-016-0533-9","article-title":"The clinical features, diagnosis and management of recurrent thymoma","volume":"11","author":"Luo","year":"2016","journal-title":"J\u00a0Cardiothorac Surg"},{"key":"10.1016\/j.jtho.2021.07.004_bib3","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1097\/JTO.0000000000000378","article-title":"Surgical management of recurrent thymic epithelial tumors a retrospective analysis based on the Japanese nationwide database","volume":"10","author":"Mizuno","year":"2015","journal-title":"J\u00a0Thorac Oncol"},{"key":"10.1016\/j.jtho.2021.07.004_bib4","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1016\/j.athoracsur.2014.04.028","article-title":"A\u00a0meta-analysis of surgical versus nonsurgical management of recurrent thymoma","volume":"98","author":"Hamaji","year":"2014","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtho.2021.07.004_bib5","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jtcvs.2009.03.033","article-title":"Comparison of patterns of relapse in thymic carcinoma and thymoma","volume":"138","author":"Huang","year":"2009","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtho.2021.07.004_bib6","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1016\/j.jtcvs.2005.07.026","article-title":"Predictors of recurrence in thymic tumors: importance of invasion, World Health Organization histology, and size","volume":"130","author":"Wright","year":"2005","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtho.2021.07.004_bib7","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.thorsurg.2008.09.005","article-title":"The role of surgery in recurrent thymic tumors","volume":"19","author":"Ruffini","year":"2009","journal-title":"Thorac Surg Clin"},{"key":"10.1016\/j.jtho.2021.07.004_bib8","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1016\/S0003-4975(03)01020-8","article-title":"Long-term outcome after multimodality treatment for stage III thymic tumors","volume":"76","author":"Venuta","year":"2003","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtho.2021.07.004_bib9","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1016\/j.athoracsur.2003.10.001","article-title":"Thymic tumors","volume":"77","author":"Detterbeck","year":"2004","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtho.2021.07.004_bib10","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/0003-4975(95)00669-C","article-title":"Thymoma: a multivariate analysis of factors predicting survival","volume":"60","author":"Blumberg","year":"1995","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtho.2021.07.004_bib11","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.lungcan.2019.09.024","article-title":"Prognostic factors after treatment for iterative thymoma recurrences: a multicentric experience","volume":"138","author":"Chiappetta","year":"2019","journal-title":"Lung Cancer"},{"key":"10.1016\/j.jtho.2021.07.004_bib12","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/jso.1146","article-title":"Recurrence of thymoma: clinicopathological features, re-operation, and outcome","volume":"78","author":"Haniuda","year":"2001","journal-title":"J\u00a0Surg Oncol"},{"key":"10.1016\/j.jtho.2021.07.004_bib13","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.1002\/1097-0142(19811201)48:11<2485::AID-CNCR2820481123>3.0.CO;2-R","article-title":"Follow-up study of thymomas with special reference to their clinical stages","volume":"48","author":"Masaoka","year":"1981","journal-title":"Cancer"},{"key":"10.1016\/j.jtho.2021.07.004_bib14","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1111\/j.1440-1827.1994.tb02936.x","article-title":"A\u00a0review of 79 thymomas: modification of staging system and reappraisal of conventional division into invasive and non-invasive thymoma","volume":"44","author":"Koga","year":"1994","journal-title":"Pathol Int"},{"key":"10.1016\/j.jtho.2021.07.004_bib15","series-title":"TNM Classification of Malignant Tumours","author":"Brierley","year":"2017"},{"key":"10.1016\/j.jtho.2021.07.004_bib16","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1097\/JTO.0000000000000154","article-title":"ITMIG consensus statement on the use of the WHO histological classification of thymoma and thymic carcinoma: refined definitions, histological criteria, and reporting","volume":"9","author":"Marx","year":"2014","journal-title":"J\u00a0Thorac Oncol"},{"key":"10.1016\/j.jtho.2021.07.004_bib17","doi-asserted-by":"crossref","first-page":"875","DOI":"10.3349\/ymj.2013.54.4.875","article-title":"Predictors of recurrence after thymoma resection","volume":"54","author":"Bae","year":"2013","journal-title":"Yonsei Med J"},{"key":"10.1016\/j.jtho.2021.07.004_bib18","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1097\/JTO.0b013e3181f13682","article-title":"Standard outcome measures for thymic malignancies","volume":"5","author":"Huang","year":"2010","journal-title":"J\u00a0Thorac Oncol"},{"key":"10.1016\/j.jtho.2021.07.004_bib19","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1097\/JTO.0000000000000017","article-title":"The IASLC\/ITMIG thymic malignancies staging project: development of a stage classification for thymic malignancies","volume":"8","author":"Detterbeck","year":"2013","journal-title":"J\u00a0Thorac Oncol"},{"key":"10.1016\/j.jtho.2021.07.004_bib20","first-page":"894","article-title":"Single-centre 40-year results of redo operation for recurrent thymomas","volume":"40","author":"Margaritora","year":"2011","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.jtho.2021.07.004_bib21","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1093\/ejcts\/ezv086","article-title":"Surgical treatment of recurrent thymoma: is it worthwhile?","volume":"49","author":"Marulli","year":"2016","journal-title":"\u2020 Eur J Cardiothorac Surg"},{"key":"10.1016\/j.jtho.2021.07.004_bib22","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.athoracsur.2016.08.086","article-title":"Iterative surgical treatment for repeated recurrences after complete resection of thymic tumors","volume":"103","author":"Fiorelli","year":"2017","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtho.2021.07.004_bib23","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1097\/JTO.0b013e3182598a91","article-title":"Clinical outcomes and prognosis of recurrent thymoma management","volume":"7","author":"Bae","year":"2012","journal-title":"J\u00a0Thorac Oncol"},{"key":"10.1016\/j.jtho.2021.07.004_bib24","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.1097\/JTO.0000000000000370","article-title":"Long-term results after treatment for recurrent thymoma: a multicenter analysis","volume":"9","author":"Sandri","year":"2014","journal-title":"J\u00a0Thorac Oncol"}],"container-title":["Journal of Thoracic Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1556086421022966?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1556086421022966?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:48:29Z","timestamp":1761562109000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1556086421022966"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":24,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["S1556086421022966"],"URL":"https:\/\/doi.org\/10.1016\/j.jtho.2021.07.004","relation":{},"ISSN":["1556-0864"],"issn-type":[{"value":"1556-0864","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The International Thymic Malignancy Interest Group Classification of Thymoma Recurrence: Survival Analysis and Perspectives","name":"articletitle","label":"Article Title"},{"value":"Journal of Thoracic Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtho.2021.07.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Published by Elsevier Inc. on behalf of International Association for the Study of Lung Cancer.","name":"copyright","label":"Copyright"}]}}