{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T10:33:58Z","timestamp":1791282838515,"version":"4.1.0"},"reference-count":263,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Ocular Surface"],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1016\/j.jtos.2012.01.005","type":"journal-article","created":{"date-parts":[[2012,2,16]],"date-time":"2012-02-16T16:36:07Z","timestamp":1329410167000},"page":"67-83","source":"Crossref","is-referenced-by-count":155,"title":["Corneal Neovascularization and the Utility of Topical VEGF Inhibition: Ranibizumab (Lucentis) Vs Bevacizumab (Avastin)"],"prefix":"10.1016","volume":"10","author":[{"given":"William","family":"Stevenson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng-Fu","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad H.","family":"Dastjerdi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulio","family":"Ferrari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reza","family":"Dana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtos.2012.01.005_bib1","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.semcdb.2007.08.014","article-title":"Maintaining transparency: a review of the developmental physiology and pathophysiology of two avascular tissues","volume":"19","author":"Beebe","year":"2008","journal-title":"Semin Cell Dev Biol"},{"key":"10.1016\/j.jtos.2012.01.005_bib2","first-page":"264","article-title":"Corneal angiogenic privilege: angiogenic and antiangiogenic factors in corneal avascularity, vasculogenesis, and wound healing (American Ophthalmological Society thesis)","volume":"104","author":"Azar","year":"2006","journal-title":"Trans Am Ophthalmol Soc"},{"key":"10.1016\/j.jtos.2012.01.005_bib3","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1097\/ICO.0b013e318201405a","article-title":"Treatments for corneal neovascularization: a review","volume":"30","author":"Gupta","year":"2011","journal-title":"Cornea"},{"issue":"7347","key":"10.1016\/j.jtos.2012.01.005_bib4","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1038\/nature10144","article-title":"Molecular mechanisms and clinical applications of angiogenesis","volume":"473","author":"Carmeliet","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.jtos.2012.01.005_bib5","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.ophtha.2005.11.019","article-title":"Intravitreal bevacizumab (Avastin) for neovascular age related macular degeneration","volume":"113","author":"Avery","year":"2006","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jtos.2012.01.005_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.ophtha.2006.05.064","article-title":"Intravitreal bevacizumab (Avastin) in the treatment of proliferative diabetic retinopathy","volume":"113","author":"Avery","year":"2006","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jtos.2012.01.005_bib7","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1007\/s00347-007-1512-2","article-title":"Inhibition of angiogenesis in the anterior chamber of the eye","volume":"104","author":"Bock","year":"2007","journal-title":"Ophthalmologe"},{"key":"10.1016\/j.jtos.2012.01.005_bib8","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1001\/jama.2011.51","article-title":"Treatment-related mortality with bevacizumab in cancer patients: a meta-analysis","volume":"305","author":"Ranpura","year":"2011","journal-title":"JAMA"},{"key":"10.1016\/j.jtos.2012.01.005_bib9","unstructured":"WHO releases the new global estimates on visual impairment. World Health Organization Web site. 2010. Available at: http:\/\/www.who.int\/blindness\/en. Accessed August 2, 2011"},{"key":"10.1016\/j.jtos.2012.01.005_bib10","first-page":"214","article-title":"Corneal blindness: a global perspective","volume":"79","author":"Whitcher","year":"2001","journal-title":"Bull World Health Organ"},{"key":"10.1016\/j.jtos.2012.01.005_bib11","unstructured":"Program for the prevention of blindness and deafness: data available on blindness. World Health Organization Web site. 2006. Available at: http:\/\/www.who.int\/blindness\/publications\/global_data.pdf. Accessed August 2, 2011"},{"key":"10.1016\/j.jtos.2012.01.005_bib12","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0039-6257(98)00035-6","article-title":"Ocular neovascularization: an epidemiologic review","volume":"43","author":"Lee","year":"1998","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib13","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1097\/00003226-198706040-00004","article-title":"Corneal neovascularization. Pathogenesis and inhibition","volume":"6","author":"Epstein","year":"1987","journal-title":"Cornea"},{"key":"10.1016\/j.jtos.2012.01.005_bib14","unstructured":"Report of the global scientific meeting on future approaches to trachoma control. Geneva, 17\u201320 June 1996. World Health Organization. 1997. Available at: http:\/\/whqlibdoc.who.int\/hq\/1996\/WHO_PBL_96.56.pdf. Accessed August 2, 2011"},{"key":"10.1016\/j.jtos.2012.01.005_bib15","series-title":"Trachoma control: a guide for programme managers","author":"Solomon","year":"2006"},{"key":"10.1016\/j.jtos.2012.01.005_bib16","unstructured":"Water sanitation and health. World Health Organization Web site. 2001. Available at: http:\/\/www.who.int\/water_sanitation_health\/diseases\/oncho\/en. Accessed August 2, 2011"},{"key":"10.1016\/j.jtos.2012.01.005_bib17","unstructured":"African Programme for Onchocerciasis Control (APOC): Ouagadougou (Burkina Faso): APOC; 2005. Final communiqu\u00e9 of the 11th session of the Joint Action Forum (JAF) of APOC, Paris, France, 6\u20139 December 2005"},{"key":"10.1016\/j.jtos.2012.01.005_bib18","unstructured":"World Health Organization. Geneva: World Health Organization; 1995. Onchocerciasis and its control. Report of a WHO expert committee on onchocerciasis control. WHO Technical Report Series 1995;852:110"},{"key":"10.1016\/j.jtos.2012.01.005_bib19","doi-asserted-by":"crossref","first-page":"e217","DOI":"10.1371\/journal.pntd.0000217","article-title":"Of mice, cattle, and humans: the immunology and treatment of river blindness","volume":"2","author":"Allen","year":"2008","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.jtos.2012.01.005_bib20","series-title":"U.S. Census Bureau Announces 2010 Census Population Counts \u2013 Apportionment Counts Delivered to President","year":"2010"},{"key":"10.1016\/j.jtos.2012.01.005_bib21","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1001\/archopht.1989.01070020221029","article-title":"Epidemiology of ocular herpes simplex. Incidence in Rochester, Minn, 1950 through 1982","volume":"107","author":"Liesegang","year":"1989","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib22","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/S0161-6420(92)31921-9","article-title":"Biology and molecular aspects of herpes simplex and varicella-zoster virus infections","volume":"99","author":"Liesegang","year":"1992","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jtos.2012.01.005_bib23","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1076\/opep.5.3.143.8364","article-title":"The global impact of eye injuries","volume":"5","author":"Negrel","year":"1998","journal-title":"Ophthalmic Epidemiol"},{"key":"10.1016\/j.jtos.2012.01.005_bib24","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1080\/08820530902801478","article-title":"Limbal stem cell deficiency and corneal neovascularization","volume":"24","author":"Lim","year":"2009","journal-title":"Semin Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib25","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S1542-0124(12)70144-1","article-title":"Aniridia and the ocular surface","volume":"2","author":"Murube","year":"2004","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jtos.2012.01.005_bib26","first-page":"330","article-title":"Comparison of topical interleukin-1 vs tumor necrosis factor-alpha blockade with corticosteroid therapy on murine corneal inflammation, neovascularization, and transplant survival (an American Ophthalmological Society thesis)","volume":"105","author":"Dana","year":"2007","journal-title":"Trans Am Ophthalmol Soc"},{"key":"10.1016\/j.jtos.2012.01.005_bib27","unstructured":"Cornea donation & transplantation statistics. Eye Bank Association of America Web site. Available at: http:\/\/www.restoresight.org\/about-us\/understanding-donation\/cornea-donation-transplantation-statistics. Accessed September 6, 2011"},{"key":"10.1016\/j.jtos.2012.01.005_bib28","first-page":"604","article-title":"Corneal neovascularization after penetrating keratoplasty","volume":"14","author":"Dana","year":"1995","journal-title":"Cornea"},{"key":"10.1016\/j.jtos.2012.01.005_bib29","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1442-9071.1987.tb00300.x","article-title":"Hierarchy of prognostic factors for corneal allograft survival","volume":"15","author":"Volker-Dieben","year":"1987","journal-title":"Aust N Z J Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib30","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1615\/CritRevImmunol.v18.i4.20","article-title":"The immunology of corneal graft rejection","volume":"18","author":"Rocha","year":"1998","journal-title":"Crit Rev Immunol"},{"key":"10.1016\/j.jtos.2012.01.005_bib31","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1001\/archopht.1992.01080220054021","article-title":"Effectiveness of histocompatibility matching in high-risk corneal transplantation. The Collaborative Corneal Transplantation Studies Research Group","volume":"110","year":"1992","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib32","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1016\/j.ophtha.2010.01.039","article-title":"Corneal neovascularization as a risk factor for graft failure and rejection after keratoplasty: an evidence-based meta-analysis","volume":"117","author":"Bachmann","year":"2010","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jtos.2012.01.005_bib33","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1080\/08820530500509358","article-title":"Angiogenesis and lymphangiogenesis-implications for corneal immunity","volume":"21","author":"Dana","year":"2006","journal-title":"Semin Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib34","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1097\/00003226-199811000-00008","article-title":"Angiogenesis in corneal diseases: histopathologic evaluation of 254 human corneal buttons with neovascularization","volume":"17","author":"Cursiefen","year":"1998","journal-title":"Cornea"},{"key":"10.1016\/j.jtos.2012.01.005_bib35","unstructured":"Barr J. 2004 Annual Report. Contact Lens Spectrum 2005, January"},{"key":"10.1016\/j.jtos.2012.01.005_bib36","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/S0896-1549(03)00056-7","article-title":"Contact lens complications","volume":"16","author":"Suchecki","year":"2003","journal-title":"Ophthalmol Clin North Am"},{"key":"10.1016\/j.jtos.2012.01.005_bib37","series-title":"Essentials in ophthalmology","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/3-540-31226-9_7","article-title":"Cornea and external eye disease","author":"Cursiefen","year":"2006"},{"key":"10.1016\/j.jtos.2012.01.005_bib38","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1080\/02713680902919557","article-title":"Mediators of neovascularization and the hypoxic cornea","volume":"34","author":"Safvati","year":"2009","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.jtos.2012.01.005_bib39","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/0002-9394(77)90200-8","article-title":"Deep corneal vascularization caused by aphakic soft contact lens wear","volume":"83","author":"Weinberg","year":"1977","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib40","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1016\/S0161-6420(91)32048-7","article-title":"Contact lens-related deep stromal intracorneal hemorrhage","volume":"98","author":"Donnenfeld","year":"1991","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jtos.2012.01.005_bib41","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1038\/nm0603-653","article-title":"Angiogenesis in health and disease","volume":"9","author":"Carmeliet","year":"2003","journal-title":"Nat Med"},{"key":"10.1016\/j.jtos.2012.01.005_bib42","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1161\/01.RES.85.3.221","article-title":"Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization","volume":"85","author":"Asahara","year":"1999","journal-title":"Circ Res"},{"key":"10.1016\/j.jtos.2012.01.005_bib43","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1089\/152581602753658385","article-title":"Endothelial progenitor cells for vascular regeneration","volume":"11","author":"Asahara","year":"2002","journal-title":"J\u00a0Hematother Stem Cell Res"},{"key":"10.1016\/j.jtos.2012.01.005_bib44","doi-asserted-by":"crossref","first-page":"C572","DOI":"10.1152\/ajpcell.00330.2003","article-title":"Endothelial progenitor cells for postnatal vasculogenesis","volume":"287","author":"Asahara","year":"2004","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1016\/j.jtos.2012.01.005_bib45","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1097\/00003226-198501000-00008","article-title":"Experimental corneal neovascularization: biomicroscopic, angiographic, and morphologic correlation","volume":"4","author":"Burger","year":"1985","journal-title":"Cornea"},{"key":"10.1016\/j.jtos.2012.01.005_bib46","doi-asserted-by":"crossref","first-page":"3502","DOI":"10.1167\/iovs.05-0309","article-title":"Contribution of bone marrow-derived pericyte precursor cells to corneal vasculogenesis","volume":"46","author":"Ozerdem","year":"2005","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib47","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/nm0195-27","article-title":"Angiogenesis in cancer, vascular, rheumatoid and other disease","volume":"1","author":"Folkman","year":"1995","journal-title":"Nat Med"},{"key":"10.1016\/j.jtos.2012.01.005_bib48","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/S0092-8674(00)80108-7","article-title":"Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis","volume":"86","author":"Hanahan","year":"1996","journal-title":"Cell"},{"key":"10.1016\/j.jtos.2012.01.005_bib49","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1096\/fasebj.13.1.9","article-title":"Vascular endothelial growth factor (VEGF) and its receptors","volume":"13","author":"Neufeld","year":"1999","journal-title":"FASEB J"},{"key":"10.1016\/j.jtos.2012.01.005_bib50","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1002\/iub.234","article-title":"Structure and function of VEGF receptors","volume":"61","author":"Stuttfeld","year":"2009","journal-title":"IUBMB Life"},{"key":"10.1016\/j.jtos.2012.01.005_bib51","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1038\/nrc2505","article-title":"VEGF-A splicing: the key to antiangiogenic therapeutics?","volume":"8","author":"Harper","year":"2008","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.jtos.2012.01.005_bib52","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1001\/archsurg.134.12.1325","article-title":"Proinflammatory mediators stimulate neutrophil-directed angiogenesis","volume":"134","author":"McCourt","year":"1999","journal-title":"Arch Surg"},{"issue":"6398","key":"10.1016\/j.jtos.2012.01.005_bib53","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1038\/359843a0","article-title":"Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis","volume":"359","author":"Shweiki","year":"1992","journal-title":"Nature"},{"key":"10.1016\/j.jtos.2012.01.005_bib54","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1350-9462(02)00043-5","article-title":"Vascular endothelial growth factors and angiogenesis in eye disease","volume":"22","author":"Witmer","year":"2003","journal-title":"Prog Retin Eye Res"},{"key":"10.1016\/j.jtos.2012.01.005_bib55","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1038\/nm0603-669","article-title":"The biology of VEGF and its receptors","volume":"9","author":"Ferrara","year":"2003","journal-title":"Nat Med"},{"key":"10.1016\/j.jtos.2012.01.005_bib56","first-page":"581","article-title":"Regulation of microvascular permeability by vascular endothelial growth factors","volume":"200","author":"Bates","year":"2002","journal-title":"J\u00a0Anat"},{"issue":"3 Pt 2","key":"10.1016\/j.jtos.2012.01.005_bib57","first-page":"H1054","article-title":"VEGF upregulates ecNOS message, protein, and NO production in human endothelial cells","volume":"274","author":"Hood","year":"1998","journal-title":"Am J Physiol"},{"key":"10.1016\/j.jtos.2012.01.005_bib58","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1002\/j.1460-2075.1996.tb00359.x","article-title":"A\u00a0novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases","volume":"15","author":"Joukov","year":"1996","journal-title":"EMBO J"},{"key":"10.1016\/j.jtos.2012.01.005_bib59","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1073\/pnas.95.2.548","article-title":"Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)","volume":"95","author":"Achen","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jtos.2012.01.005_bib60","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1038\/nm731","article-title":"Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1","volume":"8","author":"Luttun","year":"2002","journal-title":"Nat Med"},{"key":"10.1016\/j.jtos.2012.01.005_bib61","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1172\/JCI20465","article-title":"VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment","volume":"113","author":"Cursiefen","year":"2004","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.jtos.2012.01.005_bib62","first-page":"18","article-title":"Requirement for vascular endothelial growth factor in wound- and inflammation-related corneal neovascularization","volume":"39","author":"Amano","year":"1998","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib63","first-page":"2514","article-title":"Expression of vascular endothelial growth factor and its receptors in inflamed and vascularized human corneas","volume":"41","author":"Philipp","year":"2000","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib64","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1097\/ICO.0b013e31817786ad","article-title":"Subconjunctival bevacizumab for corneal neovascularization","volume":"27","author":"Doctor","year":"2008","journal-title":"Cornea"},{"key":"10.1016\/j.jtos.2012.01.005_bib65","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1097\/ICO.0b013e31819839f9","article-title":"Subconjunctival and intracorneal bevacizumab injection for corneal neovascularization in lipid keratopathy","volume":"28","author":"Oh","year":"2009","journal-title":"Cornea"},{"key":"10.1016\/j.jtos.2012.01.005_bib66","doi-asserted-by":"crossref","first-page":"34226","DOI":"10.1074\/jbc.M303183200","article-title":"Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs","volume":"278","author":"Olsen","year":"2003","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jtos.2012.01.005_bib67","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.tig.2004.08.007","article-title":"Evolution of the Fgf and Fgfr gene families","volume":"20","author":"Itoh","year":"2004","journal-title":"Trends Genet"},{"key":"10.1016\/j.jtos.2012.01.005_bib68","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1038\/nrd2792","article-title":"The FGF family: biology, pathophysiology and therapy","volume":"8","author":"Beenken","year":"2009","journal-title":"Nat Rev Drug Discov"},{"key":"10.1016\/j.jtos.2012.01.005_bib69","doi-asserted-by":"crossref","first-page":"2260","DOI":"10.1128\/MCB.20.6.2260-2268.2000","article-title":"Compensation by fibroblast growth factor 1 (FGF1) does not account for the mild phenotypic defects observed in FGF2 null mice","volume":"20","author":"Miller","year":"2000","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.jtos.2012.01.005_bib70","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1038\/nm0297-158","article-title":"Angiogenesis in ischemic heart disease","volume":"3","author":"Ware","year":"1997","journal-title":"Nat Med"},{"issue":"5075","key":"10.1016\/j.jtos.2012.01.005_bib71","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1126\/science.1382313","article-title":"Salvage of infarcted myocardium by angiogenic action of basic fibroblast growth factor","volume":"257","author":"Yanagisawa-Miwa","year":"1992","journal-title":"Science"},{"key":"10.1016\/j.jtos.2012.01.005_bib72","doi-asserted-by":"crossref","first-page":"3355","DOI":"10.1172\/JCI35298","article-title":"The FGF system has a key role in regulating vascular integrity","volume":"118","author":"Murakami","year":"2008","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.jtos.2012.01.005_bib73","first-page":"961","article-title":"In situ injury-induced release of basic-fibroblast growth factor from corneal epithelial cells","volume":"139","author":"Adamis","year":"1991","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jtos.2012.01.005_bib74","first-page":"393","article-title":"A\u00a0heparin-binding angiogenic protein\u2013basic fibroblast growth factor\u2013is stored within basement membrane","volume":"130","author":"Folkman","year":"1988","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jtos.2012.01.005_bib75","first-page":"323","article-title":"Binding of basic fibroblast growth factor to normal and neovascularized rabbit cornea","volume":"31","author":"Soubrane","year":"1990","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib76","doi-asserted-by":"crossref","first-page":"8718","DOI":"10.1167\/iovs.11-7871","article-title":"Corneal penetration of topical and subconjunctival bevacizumab (Avastin)","volume":"52","author":"Dastjerdi","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib77","doi-asserted-by":"crossref","first-page":"4769","DOI":"10.1242\/dev.00721","article-title":"Roles of PDGF in animal development","volume":"130","author":"Hoch","year":"2003","journal-title":"Development"},{"key":"10.1016\/j.jtos.2012.01.005_bib78","doi-asserted-by":"crossref","first-page":"3469","DOI":"10.1242\/dev.00574","article-title":"PVF1, a PDGF\/VEGF homolog, is sufficient to guide border cells and interacts genetically with Taiman","volume":"130","author":"McDonald","year":"2003","journal-title":"Development"},{"key":"10.1016\/j.jtos.2012.01.005_bib79","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1093\/embo-reports\/kvf242","article-title":"PVF2, a PDGF\/VEGF-like growth factor, induces hemocyte proliferation in Drosophila larvae","volume":"3","author":"Munier","year":"2002","journal-title":"EMBO Rep"},{"key":"10.1016\/j.jtos.2012.01.005_bib80","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.cytogfr.2004.03.007","article-title":"The PDGF family: four gene products form five dimeric isoforms","volume":"15","author":"Fredriksson","year":"2004","journal-title":"Cytokine Growth Factor Rev"},{"key":"10.1016\/j.jtos.2012.01.005_bib81","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1101\/gad.8.16.1875","article-title":"Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities","volume":"8","author":"Lev\u00e9en","year":"1994","journal-title":"Genes Dev"},{"key":"10.1016\/j.jtos.2012.01.005_bib82","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1101\/gad.8.16.1888","article-title":"Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice","volume":"8","author":"Soriano","year":"1994","journal-title":"Genes Dev"},{"issue":"5323","key":"10.1016\/j.jtos.2012.01.005_bib83","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1126\/science.277.5323.242","article-title":"Pericyte loss and microaneurysm formation in PDGF-B-deficient mice","volume":"277","author":"Lindahl","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.jtos.2012.01.005_bib84","doi-asserted-by":"crossref","first-page":"3047","DOI":"10.1242\/dev.126.14.3047","article-title":"Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse","volume":"126","author":"Hellstr\u00f6m","year":"1999","journal-title":"Development"},{"key":"10.1016\/j.jtos.2012.01.005_bib85","first-page":"1364","article-title":"Effect of PDGF, IL-1alpha, and BMP2\/4 on corneal fibroblast chemotaxis: expression of the platelet-derived growth factor system in the cornea","volume":"40","author":"Kim","year":"1999","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib86","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1076\/ceyr.16.8.825.8984","article-title":"Platelet-derived growth factor-BB (PDGF-BB) in tear fluid: a potential modulator of corneal wound healing following photorefractive keratectomy","volume":"16","author":"Vesaluoma","year":"1997","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.jtos.2012.01.005_bib87","first-page":"637","article-title":"Platelet-derived growth factor: receptor expression in corneas and effects on corneal cells","volume":"34","author":"Hoppenreijs","year":"1993","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib88","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1167\/iovs.05-1071","article-title":"The role of PDGF receptor inhibitors and PI3-kinase signaling in the pathogenesis of corneal neovascularization","volume":"47","author":"Dell","year":"2006","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib89","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1038\/nrm2639","article-title":"Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system","volume":"10","author":"Augustin","year":"2009","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.jtos.2012.01.005_bib90","doi-asserted-by":"crossref","first-page":"1904","DOI":"10.1073\/pnas.96.5.1904","article-title":"Angiopoietins 3 and 4: diverging gene counterparts in mice and humans","volume":"96","author":"Valenzuela","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"5322","key":"10.1016\/j.jtos.2012.01.005_bib91","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1126\/science.277.5322.55","article-title":"Angiopoietin-2, a natural antagonist for Tie2 that disrupts in\u00a0vivo angiogenesis","volume":"277","author":"Maisonpierre","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.jtos.2012.01.005_bib92","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1016\/S0092-8674(00)81813-9","article-title":"Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis","volume":"87","author":"Suri","year":"1996","journal-title":"Cell"},{"issue":"5-6","key":"10.1016\/j.jtos.2012.01.005_bib93","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0945-053X(01)00149-4","article-title":"Angiopoietin and Tie signaling pathways in vascular development","volume":"20","author":"Loughna","year":"2001","journal-title":"Matrix Biol"},{"key":"10.1016\/j.jtos.2012.01.005_bib94","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1161\/01.RES.83.3.233","article-title":"Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularization","volume":"83","author":"Asahara","year":"1998","journal-title":"Circ Res"},{"key":"10.1016\/j.jtos.2012.01.005_bib95","doi-asserted-by":"crossref","first-page":"11205","DOI":"10.1073\/pnas.172161899","article-title":"Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in\u00a0vivo","volume":"99","author":"Lobov","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jtos.2012.01.005_bib96","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1615\/CritRevEukarGeneExpr.v18.i3.30","article-title":"Matrix metalloproteinase control of capillary morphogenesis","volume":"18","author":"Ghajar","year":"2008","journal-title":"Crit Rev Eukaryot Gene Expr"},{"key":"10.1016\/j.jtos.2012.01.005_bib97","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1083\/jcb.108.2.671","article-title":"In\u00a0vitro angiogenesis on the human amniotic membrane: requirement for basic fibroblast growth factor-induced proteinases","volume":"108","author":"Mignatti","year":"1989","journal-title":"J\u00a0Cell Biol"},{"key":"10.1016\/j.jtos.2012.01.005_bib98","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1111\/1523-1747.ep12317080","article-title":"Human dermal microvascular endothelial cells produce matrix metalloproteinases in response to angiogenic factors and migration","volume":"105","author":"Cornelius","year":"1995","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jtos.2012.01.005_bib99","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1042\/bj2960803","article-title":"Regulation of matrix metalloproteinase expression in human vein and microvascular endothelial cells","volume":"296","author":"Hanemaaijer","year":"1993","journal-title":"Biochem J"},{"key":"10.1016\/j.jtos.2012.01.005_bib100","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S0021-9258(19)40250-0","article-title":"Vectorial secretion of extracellular matrix proteins, matrix-degrading proteinases, and tissue inhibitor of metalloproteinases by endothelial cells","volume":"265","author":"Unemori","year":"1990","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jtos.2012.01.005_bib101","first-page":"1048","article-title":"Reduced angiogenesis and tumor progression in gelatinase A-deficient mice","volume":"58","author":"Itoh","year":"1998","journal-title":"Cancer Res"},{"key":"10.1016\/j.jtos.2012.01.005_bib102","doi-asserted-by":"crossref","first-page":"3884","DOI":"10.1073\/pnas.97.8.3884","article-title":"Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model","volume":"97","author":"Fang","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jtos.2012.01.005_bib103","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1038\/35036374","article-title":"Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis","volume":"2","author":"Bergers","year":"2000","journal-title":"Nat Cell Biol"},{"key":"10.1016\/j.jtos.2012.01.005_bib104","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1083\/jcb.200409115","article-title":"Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors","volume":"169","author":"Lee","year":"2005","journal-title":"J\u00a0Cell Biol"},{"key":"10.1016\/j.jtos.2012.01.005_bib105","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1096\/fj.04-2140fje","article-title":"Contribution of host MMP-2 and MMP-9 to promote tumor vascularization and invasion of malignant keratinocytes","volume":"19","author":"Masson","year":"2005","journal-title":"FASEB J"},{"key":"10.1016\/j.jtos.2012.01.005_bib106","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1023\/A:1009065709676","article-title":"Induction of membrane-type matrix metalloproteinase-1 stimulates angiogenic activities of bovine aortic endothelial cells","volume":"3","author":"Jeong","year":"1999","journal-title":"Angiogenesis"},{"key":"10.1016\/j.jtos.2012.01.005_bib107","doi-asserted-by":"crossref","first-page":"4052","DOI":"10.1073\/pnas.060037197","article-title":"Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I","volume":"97","author":"Zhou","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jtos.2012.01.005_bib108","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1083\/jcb.200405001","article-title":"MT1-MMP-dependent neovessel formation within the confines of the three-dimensional extracellular matrix","volume":"167","author":"Chun","year":"2004","journal-title":"J\u00a0Cell Biol"},{"key":"10.1016\/j.jtos.2012.01.005_bib109","first-page":"913","article-title":"Expression of gelatinases A and B, and TIMPs 1 and 2 during corneal wound healing","volume":"39","author":"Ye","year":"1998","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib110","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0014-5793(01)02897-6","article-title":"Diminished corneal angiogenesis in gelatinase A-deficient mice","volume":"508","author":"Kato","year":"2001","journal-title":"FEBS Lett"},{"key":"10.1016\/j.jtos.2012.01.005_bib111","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.exer.2004.08.023","article-title":"Delayed inflammation-associated corneal neovascularization in MMP-2-deficient mice","volume":"80","author":"Samolov","year":"2005","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.jtos.2012.01.005_bib112","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1159\/000226222","article-title":"MT1-MMP-mediated cleavage of decorin in corneal angiogenesis","volume":"46","author":"Mimura","year":"2009","journal-title":"J\u00a0Vasc Res"},{"key":"10.1016\/j.jtos.2012.01.005_bib113","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1080\/02713680802461106","article-title":"Effect of MT1-MMP deficiency and overexpression in corneal keratocytes on vascular endothelial cell migration and proliferation","volume":"33","author":"Azar","year":"2008","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.jtos.2012.01.005_bib114","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1097\/ICO.0b013e3181b1165d","article-title":"Corneal epithelial MT1-MMP inhibits vascular endothelial cell proliferation and migration","volume":"29","author":"Azar","year":"2010","journal-title":"Cornea"},{"key":"10.1016\/j.jtos.2012.01.005_bib115","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1074\/jbc.270.1.308","article-title":"Induction of vascular endothelial growth factor gene expression by interleukin-1 beta in rat aortic smooth muscle cells","volume":"270","author":"Li","year":"1995","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jtos.2012.01.005_bib116","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1074\/jbc.271.2.736","article-title":"Interleukin 6 induces the expression of vascular endothelial growth factor","volume":"271","author":"Cohen","year":"1996","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jtos.2012.01.005_bib117","doi-asserted-by":"crossref","first-page":"28220","DOI":"10.1074\/jbc.271.45.28220","article-title":"Induction of vascular endothelial growth factor by tumor necrosis factor alpha in human glioma cells. Possible roles of SP-1","volume":"271","author":"Ryuto","year":"1996","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jtos.2012.01.005_bib118","doi-asserted-by":"crossref","first-page":"6271","DOI":"10.1016\/S0021-9258(17)37365-9","article-title":"Vascular endothelial growth factor is induced in response to transforming growth factor-beta in fibroblastic and epithelial cells","volume":"269","author":"Pertovaara","year":"1994","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jtos.2012.01.005_bib119","doi-asserted-by":"crossref","first-page":"3369","DOI":"10.4049\/jimmunol.170.6.3369","article-title":"IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis","volume":"170","author":"Li","year":"2003","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.jtos.2012.01.005_bib120","first-page":"985132","article-title":"Matrix metalloproteinases and tissue inhibitor of metalloproteinases are essential for the inflammatory response in cancer cells","volume":"2010","author":"Sun","year":"2010","journal-title":"J\u00a0Signal Transduct"},{"key":"10.1016\/j.jtos.2012.01.005_bib121","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1001\/archopht.125.6.783","article-title":"Very late antigen 1 blockade markedly promotes survival of corneal allografts","volume":"125","author":"Chen","year":"2007","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib122","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0002-9440(10)64363-5","article-title":"The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis","volume":"160","author":"Senger","year":"2002","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jtos.2012.01.005_bib123","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.2353\/ajpath.2007.070172","article-title":"Dexamethasone inhibits interleukin-1beta induced corneal neovascularization: role of nuclear factor-kappaB-activated stromal cells in inflammatory angiogenesis","volume":"171","author":"Nakao","year":"2007","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jtos.2012.01.005_bib124","doi-asserted-by":"crossref","first-page":"4935","DOI":"10.1167\/iovs.05-1651","article-title":"Triamcinolone acetonide inhibits IL-6- and VEGF-induced angiogenesis downstream of the IL-6 and VEGF receptors","volume":"47","author":"Ebrahem","year":"2006","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"7114","key":"10.1016\/j.jtos.2012.01.005_bib125","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1038\/nature05249","article-title":"Corneal avascularity is due to soluble VEGF receptor-1","volume":"443","author":"Ambati","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.jtos.2012.01.005_bib126","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1136\/bjo.2006.107417","article-title":"Soluble vascular endothelial growth factor receptor-1 contributes to the corneal antiangiogenic barrier","volume":"91","author":"Ambati","year":"2007","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib127","doi-asserted-by":"crossref","first-page":"10705","DOI":"10.1073\/pnas.90.22.10705","article-title":"Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor","volume":"90","author":"Kendall","year":"1993","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jtos.2012.01.005_bib128","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1006\/bbrc.1996.1355","article-title":"Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR","volume":"226","author":"Kendall","year":"1996","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.jtos.2012.01.005_bib129","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1038\/nm.2018","article-title":"Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth","volume":"15","author":"Albuquerque","year":"2009","journal-title":"Nat Med"},{"key":"10.1016\/j.jtos.2012.01.005_bib130","doi-asserted-by":"crossref","first-page":"11405","DOI":"10.1073\/pnas.0506112103","article-title":"Nonvascular VEGF receptor 3 expression by corneal epithelium maintains avascularity and vision","volume":"103","author":"Cursiefen","year":"2006","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jtos.2012.01.005_bib131","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.2353\/ajpath.2009.080515","article-title":"Contribution of macrophages to angiogenesis induced by vascular endothelial growth factor receptor-3-specific ligands","volume":"175","author":"Chung","year":"2009","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jtos.2012.01.005_bib132","doi-asserted-by":"crossref","first-page":"11131","DOI":"10.1073\/pnas.211268598","article-title":"Crystal structure of human PEDF, a potent antiangiogenic and neurite growth-promoting factor","volume":"98","author":"Simonovic","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jtos.2012.01.005_bib133","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1002\/jcb.22072","article-title":"Characterization of PEDF: a multi-functional serpin family protein","volume":"106","author":"Filleur","year":"2009","journal-title":"J\u00a0Cell Biochem"},{"issue":"5425","key":"10.1016\/j.jtos.2012.01.005_bib134","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1126\/science.285.5425.245","article-title":"Pigment epithelium-derived factor: a potent inhibitor of angiogenesis","volume":"285","author":"Dawson","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.jtos.2012.01.005_bib135","doi-asserted-by":"crossref","first-page":"3912","DOI":"10.1167\/iovs.05-1267","article-title":"Pigment epithelial growth factor suppresses inflammation by modulating macrophage activation","volume":"47","author":"Zamiri","year":"2006","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib136","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/978-1-4615-5391-5_21","article-title":"Structure-function studies on PEDF. A noninhibitory serpin with neurotrophic activity","volume":"425","author":"Becerra","year":"1997","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.jtos.2012.01.005_bib137","first-page":"821","article-title":"Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth","volume":"43","author":"Duh","year":"2002","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib138","first-page":"2428","article-title":"Regression of ocular neovascularization in response to increased expression of pigment epithelium-derived factor","volume":"43","author":"Mori","year":"2002","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib139","first-page":"154","article-title":"Localization of pigment epithelium derived factor (PEDF) in developing and adult human ocular tissues","volume":"7","author":"Karakousis","year":"2001","journal-title":"Mol Vis"},{"key":"10.1016\/j.jtos.2012.01.005_bib140","first-page":"1168","article-title":"Expression of pigment epithelium-derived factor in normal adult rat eye and experimental choroidal neovascularization","volume":"43","author":"Ogata","year":"2002","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib141","doi-asserted-by":"crossref","first-page":"45400","DOI":"10.1074\/jbc.M208339200","article-title":"Mapping the type I collagen-binding site on pigment epithelium-derived factor. Implications for its antiangiogenic activity","volume":"277","author":"Meyer","year":"2002","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jtos.2012.01.005_bib142","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1097\/ICO.0b013e3181cc7987","article-title":"Inhibition of chemical cautery-induced corneal neovascularization by topical pigment epithelium-derived factor eyedrops","volume":"29","author":"Jin","year":"2010","journal-title":"Cornea"},{"key":"10.1016\/j.jtos.2012.01.005_bib143","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/0092-8674(94)90200-3","article-title":"Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma","volume":"79","author":"O\u2019Reilly","year":"1994","journal-title":"Cell"},{"key":"10.1016\/j.jtos.2012.01.005_bib144","doi-asserted-by":"crossref","first-page":"28823","DOI":"10.1074\/jbc.272.46.28823","article-title":"Angiostatin-converting enzyme activities of human matrilysin (MMP-7) and gelatinase B\/type IV collagenase (MMP-9)","volume":"272","author":"Patterson","year":"1997","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jtos.2012.01.005_bib145","doi-asserted-by":"crossref","first-page":"2811","DOI":"10.1073\/pnas.96.6.2811","article-title":"Angiostatin binds ATP synthase on the surface of human endothelial cells","volume":"96","author":"Moser","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jtos.2012.01.005_bib146","doi-asserted-by":"crossref","first-page":"6656","DOI":"10.1073\/pnas.131067798","article-title":"Endothelial cell surface F1-F0 ATP synthase is active in ATP synthesis and is inhibited by angiostatin","volume":"98","author":"Moser","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jtos.2012.01.005_bib147","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1083\/jcb.152.6.1247","article-title":"Angiomotin: an angiostatin binding protein that regulates endothelial cell migration and tube formation","volume":"152","author":"Troyanovsky","year":"2001","journal-title":"J\u00a0Cell Biol"},{"key":"10.1016\/j.jtos.2012.01.005_bib148","doi-asserted-by":"crossref","first-page":"39562","DOI":"10.1074\/jbc.M101815200","article-title":"Specific interaction of angiostatin with integrin alpha(v)beta(3) in endothelial cells","volume":"276","author":"Tarui","year":"2001","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jtos.2012.01.005_bib149","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1182\/blood-2002-02-0582","article-title":"Angiostatin selectively inhibits signaling by hepatocyte growth factor in endothelial and smooth muscle cells","volume":"101","author":"Wajih","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.jtos.2012.01.005_bib150","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1042\/bj3350001","article-title":"Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation","volume":"335","author":"Coffer","year":"1998","journal-title":"Biochem J"},{"key":"10.1016\/j.jtos.2012.01.005_bib151","first-page":"279","article-title":"Oncogenic transformation of cells by a conditionally active form of the protein kinase Akt\/PKB","volume":"11","author":"Mirza","year":"2000","journal-title":"Cell Growth Differ"},{"key":"10.1016\/j.jtos.2012.01.005_bib152","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/1479-5876-7-5","article-title":"Angiostatin antiangiogenesis requires IL-12: the innate immune system as a key target","volume":"7","author":"Albini","year":"2009","journal-title":"J\u00a0Transl Med"},{"key":"10.1016\/j.jtos.2012.01.005_bib153","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1096\/fj.01-0651fje","article-title":"Neutrophils as a key cellular target for angiostatin: implications for regulation of angiogenesis and inflammation","volume":"16","author":"Benelli","year":"2002","journal-title":"FASEB J"},{"key":"10.1016\/j.jtos.2012.01.005_bib154","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1182\/blood-2004-01-0166","article-title":"Angiostatin is a novel anti-inflammatory factor by inhibiting leukocyte recruitment","volume":"105","author":"Chavakis","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.jtos.2012.01.005_bib155","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1076\/ceyr.18.3.186.5367","article-title":"Diurnal variations in angiostatin in human tear fluid: a possible role in prevention of corneal neovascularization","volume":"18","author":"Sack","year":"1999","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.jtos.2012.01.005_bib156","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.exer.2003.09.005","article-title":"Antiangiogenic role of angiostatin during corneal wound healing","volume":"78","author":"Gabison","year":"2004","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.jtos.2012.01.005_bib157","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1001\/archopht.120.8.1063","article-title":"Angiostatin inhibits and regresses corneal neovascularization","volume":"120","author":"Ambati","year":"2002","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib158","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0092-8674(00)81848-6","article-title":"Endostatin: an endogenous inhibitor of angiogenesis and tumor growth","volume":"88","author":"O\u2019Reilly","year":"1997","journal-title":"Cell"},{"issue":"19","key":"10.1016\/j.jtos.2012.01.005_bib159","doi-asserted-by":"crossref","first-page":"8763","DOI":"10.1073\/pnas.92.19.8763","article-title":"Mouse Col18a1 is expressed in a tissue-specific manner as three alternative variants and is localized in basement membrane zones","volume":"92","author":"Muragaki","year":"1995","journal-title":"Proc Natl Acad Sci U\u00a0S A"},{"key":"10.1016\/j.jtos.2012.01.005_bib160","doi-asserted-by":"crossref","first-page":"4234","DOI":"10.1073\/pnas.91.10.4234","article-title":"Alpha 1(XVIII), a collagen chain with frequent interruptions in the collagenous sequence, a distinct tissue distribution, and homology with type XV collagen","volume":"91","author":"Rehn","year":"1994","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"19","key":"10.1016\/j.jtos.2012.01.005_bib161","doi-asserted-by":"crossref","first-page":"13929","DOI":"10.1016\/S0021-9258(17)36737-6","article-title":"Primary structure of the alpha 1 chain of mouse type XVIII collagen, partial structure of the corresponding gene, and comparison of the alpha 1(XVIII) chain with its homologue, the alpha 1(XV) collagen chain","volume":"269","author":"Rehn","year":"1994","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jtos.2012.01.005_bib162","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/S0002-9440(10)65603-9","article-title":"The short and long forms of type XVIII collagen show clear tissue specificities in their expression and location in basement membrane zones in humans","volume":"153","author":"Saarela","year":"1998","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jtos.2012.01.005_bib163","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0014-5793(00)02249-3","article-title":"Generation and degradation of human endostatin proteins by various proteinases","volume":"486","author":"Ferreras","year":"2000","journal-title":"FEBS Lett"},{"issue":"31","key":"10.1016\/j.jtos.2012.01.005_bib164","doi-asserted-by":"crossref","first-page":"27872","DOI":"10.1074\/jbc.M202771200","article-title":"Endostatin blocks vascular endothelial growth factor-mediated signaling via direct interaction with KDR\/Flk-1","volume":"277","author":"Kim","year":"2002","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jtos.2012.01.005_bib165","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1093\/hmg\/9.13.2051","article-title":"Collagen XVIII, containing an endogenous inhibitor of angiogenesis and tumor growth, plays a critical role in the maintenance of retinal structure and in neural tube closure (Knobloch syndrome)","volume":"9","author":"Serti\u00e9","year":"2000","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.jtos.2012.01.005_bib166","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1093\/emboj\/21.7.1535","article-title":"Lack of collagen XVIII\/endostatin results in eye abnormalities","volume":"21","author":"Fukai","year":"2002","journal-title":"EMBO J"},{"key":"10.1016\/j.jtos.2012.01.005_bib167","first-page":"2517","article-title":"Matrilysin cleavage of corneal collagen type XVIII NC1 domain and generation of a 28-kDa fragment","volume":"42","author":"Lin","year":"2001","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib168","doi-asserted-by":"crossref","first-page":"8005","DOI":"10.1073\/pnas.0402551101","article-title":"E-selectin is required for the antiangiogenic activity of endostatin","volume":"101","author":"Yu","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"17","key":"10.1016\/j.jtos.2012.01.005_bib169","doi-asserted-by":"crossref","first-page":"3601","DOI":"10.1016\/j.febslet.2005.05.043","article-title":"Functional characterization of neostatins, the MMP-derived, enzymatic cleavage products of type XVIII collagen","volume":"579","author":"Chang","year":"2005","journal-title":"FEBS Lett"},{"issue":"17","key":"10.1016\/j.jtos.2012.01.005_bib170","doi-asserted-by":"crossref","first-page":"2515","DOI":"10.1016\/j.febslet.2008.06.014","article-title":"Neostatin-7 regulates bFGF-induced corneal lymphangiogenesis","volume":"582","author":"Kojima","year":"2008","journal-title":"FEBS Lett"},{"issue":"2-3","key":"10.1016\/j.jtos.2012.01.005_bib171","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.mvr.2007.05.005","article-title":"Type IV collagen-derived angiogenesis inhibitors","volume":"74","author":"Mundel","year":"2007","journal-title":"Microvasc Res"},{"key":"10.1016\/j.jtos.2012.01.005_bib172","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1159\/000322804","article-title":"Inhibitory effect of canstatin in alkali burn-induced corneal neovascularization","volume":"46","author":"Wang","year":"2011","journal-title":"Ophthalmic Res"},{"key":"10.1016\/j.jtos.2012.01.005_bib173","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0304-3835(01)00772-8","article-title":"MMP-7 (matrilysin) accelerated growth of human umbilical vein endothelial cells","volume":"177","author":"Huo","year":"2002","journal-title":"Cancer Lett"},{"key":"10.1016\/j.jtos.2012.01.005_bib174","doi-asserted-by":"crossref","first-page":"7194","DOI":"10.1038\/sj.onc.1210535","article-title":"The VEGF angiogenic switch of fibroblasts is regulated by MMP-7 from cancer cells","volume":"26","author":"Ito","year":"2007","journal-title":"Oncogene"},{"key":"10.1016\/j.jtos.2012.01.005_bib175","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.1182\/blood-2008-08-172742","article-title":"Degradation of soluble VEGF receptor-1 by MMP-7 allows VEGF access to endothelial cells","volume":"113","author":"Ito","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.jtos.2012.01.005_bib176","first-page":"20","article-title":"Immunolocalization and gene expression of matrilysin during corneal wound healing","volume":"40","author":"Lu","year":"1999","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib177","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1167\/iovs.01-1058","article-title":"Corneal neovascularization after excimer keratectomy wounds in matrilysin-deficient mice","volume":"44","author":"Kure","year":"2003","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib178","doi-asserted-by":"crossref","first-page":"799","DOI":"10.3109\/02713683.2010.494239","article-title":"MMP-7 knock-in corneal fibroblast cell lines secrete MMP-7 with proteolytic activity towards collagen XVIII","volume":"35","author":"Yeh","year":"2010","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.jtos.2012.01.005_bib179","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/S0022-2143(97)90141-4","article-title":"Endothelial cell mitogenesis induced by LPA: inhibition by thrombospondin-1 and thrombospondin-2","volume":"129","author":"Panetti","year":"1997","journal-title":"J\u00a0Lab Clin Med"},{"key":"10.1016\/j.jtos.2012.01.005_bib180","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1083\/jcb.111.2.765","article-title":"Platelet thrombospondin modulates endothelial cell adhesion, motility, and growth: a potential angiogenesis regulatory factor","volume":"111","author":"Taraboletti","year":"1990","journal-title":"J\u00a0Cell Biol"},{"key":"10.1016\/j.jtos.2012.01.005_bib181","doi-asserted-by":"crossref","first-page":"5026","DOI":"10.1073\/pnas.88.11.5026","article-title":"Thrombospondin exerts an antiangiogenic effect on cord formation by endothelial cells in\u00a0vitro","volume":"88","author":"Iruela-Arispe","year":"1991","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jtos.2012.01.005_bib182","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/71517","article-title":"Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1","volume":"6","author":"Jim\u00e9nez","year":"2000","journal-title":"Nat Med"},{"key":"10.1016\/j.jtos.2012.01.005_bib183","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1007\/s004410050877","article-title":"Immunolocalisation of thrombospondin 1 in human, bovine and rabbit cornea","volume":"289","author":"Hiscott","year":"1997","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.jtos.2012.01.005_bib184","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1167\/iovs.03-0940","article-title":"Roles of thrombospondin-1 and -2 in regulating corneal and iris angiogenesis","volume":"45","author":"Cursiefen","year":"2004","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib185","doi-asserted-by":"crossref","first-page":"4356","DOI":"10.1167\/iovs.05-1656","article-title":"Activation of CD36 inhibits and induces regression of inflammatory corneal neovascularization","volume":"47","author":"Mwaikambo","year":"2006","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib186","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1084\/jem.20092277","article-title":"Thrombospondin 1 inhibits inflammatory lymphangiogenesis by CD36 ligation on monocytes","volume":"208","author":"Cursiefen","year":"2011","journal-title":"J\u00a0Exp Med"},{"key":"10.1016\/j.jtos.2012.01.005_bib187","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1097\/ICO.0b013e31817780b6","article-title":"Genetic ablation of CD36 induces age-related corneal neovascularization","volume":"27","author":"Mwaikambo","year":"2008","journal-title":"Cornea"},{"issue":"5239","key":"10.1016\/j.jtos.2012.01.005_bib188","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1126\/science.270.5239.1189","article-title":"Fas ligand-induced apoptosis as a mechanism of immune privilege","volume":"270","author":"Griffith","year":"1995","journal-title":"Science"},{"key":"10.1016\/j.jtos.2012.01.005_bib189","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S1074-7613(00)80305-2","article-title":"CD95-induced apoptosis of lymphocytes in an immune privileged site induces immunological tolerance","volume":"5","author":"Griffith","year":"1996","journal-title":"Immunity"},{"key":"10.1016\/j.jtos.2012.01.005_bib190","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1167\/iovs.02-0299","article-title":"FasL-Fas interactions regulate neovascularization in the cornea","volume":"44","author":"Stuart","year":"2003","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib191","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1146\/annurev.immunol.26.021607.090331","article-title":"PD-1 and its ligands in tolerance and immunity","volume":"26","author":"Keir","year":"2008","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.jtos.2012.01.005_bib192","doi-asserted-by":"crossref","first-page":"1922","DOI":"10.1016\/j.ajpath.2010.12.027","article-title":"A\u00a0novel function for programmed death ligand-1 regulation of angiogenesis","volume":"178","author":"Jin","year":"2011","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jtos.2012.01.005_bib193","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1097\/00055735-200108000-00002","article-title":"Corneal neovascularization","volume":"12","author":"Chang","year":"2001","journal-title":"Curr Opin Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib194","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1007\/s004170100313","article-title":"Impact of short-term versus long-term topical steroids on corneal neovascularization after non-high-risk keratoplasty","volume":"239","author":"Cursiefen","year":"2001","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib195","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1111\/j.1749-6632.1975.tb36064.x","article-title":"Corticosteroid inhibition of chemotactic lymphokine production by T and B lymphocytes","volume":"256","author":"Wahl","year":"1975","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib196","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1056\/NEJM197208242870806","article-title":"Corticosteroids and lymphoid cells","volume":"287","author":"Claman","year":"1972","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jtos.2012.01.005_bib197","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.4049\/jimmunol.129.5.1803","article-title":"Corticosteroids inhibit murine macrophage Ia expression and interleukin 1 production","volume":"129","author":"Snyder","year":"1982","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.jtos.2012.01.005_bib198","doi-asserted-by":"crossref","first-page":"2439","DOI":"10.1002\/eji.1830201112","article-title":"Glucocorticoids inhibit the production of IL6 from monocytes, endothelial cells and fibroblasts","volume":"20","author":"Waage","year":"1990","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.jtos.2012.01.005_bib199","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/S0031-6989(81)80027-6","article-title":"Hydrocortisone inhibits platelet prostaglandin and endothelial prostacyclin production","volume":"13","author":"J\u00f8rgensen","year":"1981","journal-title":"Pharmacol Res Commun"},{"key":"10.1016\/j.jtos.2012.01.005_bib200","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1167\/iovs.02-0346","article-title":"Topical nepafenac inhibits ocular neovascularization","volume":"44","author":"Takahashi","year":"2003","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib201","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1136\/bjo.68.9.656","article-title":"Topical indomethacin effect on neovascularization of the cornea and on prostaglandin E2 levels","volume":"68","author":"Frucht","year":"1984","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib202","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/0002-9394(78)90289-1","article-title":"Neovasculogenic ability of prostaglandins, growth factors, and synthetic chemoattractants","volume":"86","author":"BenEzra","year":"1978","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib203","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1016\/S0161-6420(00)00538-8","article-title":"Keratitis, ulceration, and perforation associated with topical nonsteroidal anti-inflammatory drugs","volume":"108","author":"Guidera","year":"2001","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jtos.2012.01.005_bib204","unstructured":"Halldorsson T. Alteration of optical and thermal properties of blood by Nd:YAG laser irradiation. Proceedings of the 4th congress of the international society for laser surgery. Tokyo, Japan, Nov 23\u201327, 1981"},{"key":"10.1016\/j.jtos.2012.01.005_bib205","first-page":"595","article-title":"Laser photocoagulation for corneal stromal vascularization","volume":"90","author":"Nirankari","year":"1992","journal-title":"Trans Am Ophthalmol Soc"},{"key":"10.1016\/j.jtos.2012.01.005_bib206","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0161-6420(92)31996-7","article-title":"Corneal laser photocoagulation for treatment of neovascularization. Efficacy of 577 nm yellow dye laser","volume":"99","author":"Baer","year":"1992","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jtos.2012.01.005_bib207","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1097\/00003226-199405000-00013","article-title":"Hemorrhage complicating YAG laser feeder vessel coagulation of cornea vascularization","volume":"13","author":"Parsa","year":"1994","journal-title":"Cornea"},{"key":"10.1016\/j.jtos.2012.01.005_bib208","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1136\/bjo.60.6.464","article-title":"Corneal neovascularization treated with argon laser","volume":"60","author":"Cherry","year":"1976","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib209","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1136\/bjo.66.2.127","article-title":"Treatment of lipid keratopathy with argon laser","volume":"66","author":"Marsh","year":"1982","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib210","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1136\/bjo.72.12.900","article-title":"Argon laser treatment of lipid keratopathy","volume":"72","author":"Marsh","year":"1988","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib211","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1016\/S0161-6420(86)33581-4","article-title":"Corneal argon laser photocoagulation for neovascularization in penetrating keratoplasty","volume":"93","author":"Nirankari","year":"1986","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jtos.2012.01.005_bib212","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1097\/ICO.0b013e318180e50f","article-title":"Bevacizumab (avastin) and argon laser to treat neovascularization in corneal transplant surgery","volume":"27","author":"Gerten","year":"2008","journal-title":"Cornea"},{"key":"10.1016\/j.jtos.2012.01.005_bib213","first-page":"50","article-title":"Necrotizing scleritis following laser therapy for corneal vascularization","volume":"41","author":"Pai","year":"2009","journal-title":"Ann Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib214","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1002\/jpp.328","article-title":"Basic principles of photodynamic therapy","volume":"5","author":"Macdonald","year":"2001","journal-title":"J\u00a0Porphyrins Phthalocyanines"},{"key":"10.1016\/j.jtos.2012.01.005_bib215","first-page":"2326","article-title":"Identification of singlet oxygen as the cytotoxic agent in photo-inactivation of a murine tumor","volume":"36","author":"Weishaupt","year":"1976","journal-title":"Cancer Res"},{"key":"10.1016\/j.jtos.2012.01.005_bib216","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/0022-4804(88)90195-3","article-title":"The effect of photodynamic therapy on the microcirculation","volume":"45","author":"Reed","year":"1988","journal-title":"J\u00a0Surg Res"},{"key":"10.1016\/j.jtos.2012.01.005_bib217","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1089\/clm.1996.14.323","article-title":"Vascular effects of photodynamic therapy","volume":"14","author":"Fingar","year":"1996","journal-title":"J\u00a0Clin Laser Med Surg"},{"key":"10.1016\/j.jtos.2012.01.005_bib218","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1097\/00003226-200307000-00018","article-title":"Photodynamic therapy of corneal neovascularization with verteporfin","volume":"22","author":"Fossarello","year":"2003","journal-title":"Cornea"},{"key":"10.1016\/j.jtos.2012.01.005_bib219","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.ajo.2007.05.028","article-title":"Photodynamic therapy with verteporfin for corneal neovascularization","volume":"144","author":"Yoon","year":"2007","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib220","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1097\/00003226-200211000-00007","article-title":"Fluorescein-potentiated argon laser therapy improves symptoms and appearance of corneal neovascularization","volume":"21","author":"Gordon","year":"2002","journal-title":"Cornea"},{"key":"10.1016\/j.jtos.2012.01.005_bib221","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/j.ajo.2005.11.003","article-title":"Argon laser photodynamic therapy of human corneal neovascularization after intravenous administration of dihematoporphyrin ether","volume":"141","author":"Sheppard","year":"2006","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib222","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1001\/archopht.1989.01070020575043","article-title":"Promotion of graft survival by photothrombotic occlusion of corneal neovascularization","volume":"107","author":"Corrent","year":"1989","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib223","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1136\/bjo.2003.035071","article-title":"Photodynamic therapy for corneal neovascularisation and lipid degeneration","volume":"88","author":"Brooks","year":"2004","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib224","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1097\/ICO.0b013e3181dc81a0","article-title":"Photodynamic therapy with verteporfin combined with subconjunctival injection of bevacizumab for corneal neovascularization","volume":"30","author":"You","year":"2011","journal-title":"Cornea"},{"key":"10.1016\/j.jtos.2012.01.005_bib225","first-page":"2148","article-title":"Fine needle diathermy occlusion of corneal vessels","volume":"41","author":"Pillai","year":"2000","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib226","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1097\/01.ico.0000248383.09272.ee","article-title":"Electrolysis-needle cauterization of corneal vessels in patients with lipid keratopathy","volume":"26","author":"Wertheim","year":"2007","journal-title":"Cornea"},{"key":"10.1016\/j.jtos.2012.01.005_bib227","doi-asserted-by":"crossref","first-page":"23","DOI":"10.3126\/nepjoph.v3i1.4274","article-title":"Fine needle diathermy - A choice for managing corneal vascularization","volume":"3","author":"Thatte","year":"2011","journal-title":"Nepal J Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib228","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0161-6420(89)32833-8","article-title":"Limbal autograft transplantation for ocular surface disorders","volume":"96","author":"Kenyon","year":"1989","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jtos.2012.01.005_bib229","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/S0161-6420(02)00960-0","article-title":"Long-term outcome of keratolimbal allograft with or without penetrating keratoplasty for total limbal stem cell deficiency","volume":"109","author":"Solomon","year":"2002","journal-title":"Ophthalmology"},{"issue":"9057","key":"10.1016\/j.jtos.2012.01.005_bib230","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/S0140-6736(96)11188-0","article-title":"Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium","volume":"349","author":"Pellegrini","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.jtos.2012.01.005_bib231","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1016\/j.ophtha.2009.01.005","article-title":"Characterization of the corneal surface in limbal stem cell deficiency and after transplantation of cultivated limbal epithelium","volume":"116","author":"Pauklin","year":"2009","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jtos.2012.01.005_bib232","first-page":"1138","article-title":"Autologous transplantation of conjunctival epithelial cells cultured on amniotic membrane in a rabbit model","volume":"13","author":"Ono","year":"2007","journal-title":"Mol Vis"},{"key":"10.1016\/j.jtos.2012.01.005_bib233","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1167\/iovs.09-3379","article-title":"Cultivated human conjunctival epithelial transplantation for total limbal stem cell deficiency","volume":"51","author":"Ang","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib234","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1097\/00055735-200108000-00006","article-title":"Amniotic membrane surgery","volume":"12","author":"Sippel","year":"2001","journal-title":"Curr Opin Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib235","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S1542-0124(12)70059-9","article-title":"How does amniotic membrane work?","volume":"2","author":"Tseng","year":"2004","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jtos.2012.01.005_bib236","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.ajo.2008.03.018","article-title":"A\u00a0systematic literature review of surgical interventions for limbal stem cell deficiency in humans","volume":"146","author":"Cauchi","year":"2008","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib237","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/j.ajo.2008.01.009","article-title":"Sutureless amniotic membrane transplantation for partial limbal stem cell deficiency","volume":"145","author":"Kheirkhah","year":"2008","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib238","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1038\/nrd1381","article-title":"Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer","volume":"3","author":"Ferrara","year":"2004","journal-title":"Nat Rev Drug Discov"},{"key":"10.1016\/j.jtos.2012.01.005_bib239","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1097\/00006982-200603000-00005","article-title":"Intravitreal bevacizumab (Avastin) treatment of macular edema in central retinal vein occlusion: a short-term study","volume":"26","author":"Iturralde","year":"2006","journal-title":"Retina"},{"key":"10.1016\/j.jtos.2012.01.005_bib240","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/j.ajo.2006.06.066","article-title":"Intravitreal bevacizumab (Avastin) in the treatment of neovascular glaucoma","volume":"142","author":"Iliev","year":"2006","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib241","series-title":"Avastin package insert","year":"2009"},{"key":"10.1016\/j.jtos.2012.01.005_bib242","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1046\/j.1365-2249.2002.01808.x","article-title":"Penetration of engineered antibody fragments into the eye","volume":"128","author":"Thiel","year":"2002","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.jtos.2012.01.005_bib243","first-page":"67","article-title":"Influence of format on in\u00a0vitro penetration of antibody fragments through porcine cornea","volume":"128","author":"Brereton","year":"2002","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.jtos.2012.01.005_bib244","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1001\/archopht.125.6.834","article-title":"Topical bevacizumab therapy for corneal neovascularization","volume":"125","author":"DeStafeno","year":"2007","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib245","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/s00417-007-0684-4","article-title":"Bevacizumab (Avastin) eye drops inhibit corneal neovascularization","volume":"246","author":"Bock","year":"2008","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib246","doi-asserted-by":"crossref","first-page":"e33","DOI":"10.1016\/j.ophtha.2008.02.013","article-title":"The effect of topical bevacizumab on corneal neovascularization","volume":"115","author":"Kim","year":"2008","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jtos.2012.01.005_bib247","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1001\/archophthalmol.2009.18","article-title":"Topical bevacizumab in the treatment of corneal neovascularization: results of a prospective, open-label, noncomparative study","volume":"127","author":"Dastjerdi","year":"2009","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib248","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1007\/s00417-009-1099-1","article-title":"Short- and long-term safety profile and efficacy of topical bevacizumab (Avastin) eye drops against corneal neovascularization","volume":"247","author":"Koenig","year":"2009","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib249","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1167\/iovs.04-0601","article-title":"Preclinical pharmacokinetics of Ranibizumab (rhuFabV2) after a single intravitreal administration","volume":"46","author":"Gaudreault","year":"2005","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib250","unstructured":"Ferrari G, Okanobo A, Dastjerdi M, et\u00a0al. Topical ranibizumab as a treatment of corneal neovascularization. Manuscript submitted for publication,\u00a02011."},{"key":"10.1016\/j.jtos.2012.01.005_bib251","article-title":"Sustained efficacy of topical bevacizumab in the treatment of corneal neovascularization (NV)","author":"Cheng","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2012.01.005_bib252","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1056\/NEJMoa1102673","article-title":"Ranibizumab and bevacizumab for neovascular age-related macular degeneration","volume":"364","author":"Group","year":"2011","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jtos.2012.01.005_bib253","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1056\/NEJMp068185","article-title":"The price of sight\u2013ranibizumab, bevacizumab, and the treatment of macular degeneration","volume":"355","author":"Steinbrook","year":"2006","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jtos.2012.01.005_bib254","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.expneurol.2004.01.022","article-title":"New roles for VEGF in nervous tissue\u2013beyond blood vessels","volume":"187","author":"Rosenstein","year":"2004","journal-title":"Exp Neurol"},{"key":"10.1016\/j.jtos.2012.01.005_bib255","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1097\/IAE.0b013e3182278ab4","article-title":"A\u00a0systematic review of the adverse events of intravitreal anti-vascular endothelial growth factor injections","volume":"31","author":"Van der Reis","year":"2011","journal-title":"Retina"},{"key":"10.1016\/j.jtos.2012.01.005_bib256","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1136\/bjo.2011.204701","article-title":"Consensus statement on indications for antiangiogenic therapy in the management of corneal diseases associated with neovascularisation: outcome of an expert roundtable","volume":"96","author":"Cursiefen","year":"2012","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib257","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1016\/j.ophtha.2011.03.020","article-title":"The 1-year results of CLEAR-IT 2, a phase 2 study of vascular endothelial growth factor trap-eye dosed as-needed after 12-week fixed dosing","volume":"118","author":"Heier","year":"2011","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jtos.2012.01.005_bib258","doi-asserted-by":"crossref","first-page":"375","DOI":"10.3109\/02713681003597230","article-title":"A\u00a0siRNA targeting vascular endothelial growth factor-A inhibiting experimental corneal neovascularization","volume":"35","author":"Zuo","year":"2010","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.jtos.2012.01.005_bib259","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1159\/000324994","article-title":"Inhibitory effects of SU5416, a selective vascular endothelial growth factor receptor tyrosine kinase inhibitor, on experimental corneal neovascularization","volume":"47","author":"Keskin","year":"2011","journal-title":"Ophthalmic Res"},{"key":"10.1016\/j.jtos.2012.01.005_bib260","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1007\/s00417-011-1709-6","article-title":"Combination of vascular endothelial growth factor receptor\/platelet-derived growth factor receptor inhibition markedly improves the antiangiogenic efficacy for advanced stage mouse corneal neovascularization","volume":"249","author":"Chaoran","year":"2011","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.jtos.2012.01.005_bib261","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.1158\/0008-5472.CAN-09-1977","article-title":"Complementary actions of inhibitors of angiopoietin-2 and VEGF on tumor angiogenesis and growth","volume":"70","author":"Hashizume","year":"2010","journal-title":"Cancer Res"},{"key":"10.1016\/j.jtos.2012.01.005_bib262","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1124\/jpet.108.147496","article-title":"Potent in\u00a0vivo antiangiogenic effects of GS-101 (5\u2019-TATCCGGAGGGCTCGCCATGCTGCT-3\u2019), an antisense oligonucleotide preventing the expression of insulin receptor substrate-1","volume":"329","author":"Al-Mahmood","year":"2009","journal-title":"J\u00a0Pharmacol Exp Ther"},{"key":"10.1016\/j.jtos.2012.01.005_bib263","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1016\/j.ophtha.2009.04.016","article-title":"GS-101 antisense oligonucleotide eye drops inhibit corneal neovascularization: interim results of a randomized phase II trial","volume":"116","author":"Cursiefen","year":"2009","journal-title":"Ophthalmology"}],"container-title":["The Ocular Surface"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S154201241200016X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S154201241200016X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T19:31:10Z","timestamp":1686771070000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S154201241200016X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4]]},"references-count":263,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["S154201241200016X"],"URL":"https:\/\/doi.org\/10.1016\/j.jtos.2012.01.005","relation":{},"ISSN":["1542-0124"],"issn-type":[{"value":"1542-0124","type":"print"}],"subject":[],"published":{"date-parts":[[2012,4]]}}}