{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T18:19:04Z","timestamp":1790187544597,"version":"4.1.0"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,3,28]],"date-time":"2023-03-28T00:00:00Z","timestamp":1679961600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81970765"],"award-info":[{"award-number":["81970765"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81973351"],"award-info":[{"award-number":["81973351"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82171250"],"award-info":[{"award-number":["82171250"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Ocular Surface"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.jtos.2023.03.002","type":"journal-article","created":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T15:57:59Z","timestamp":1679932679000},"page":"131-140","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":67,"special_numbering":"C","title":["MicroRNAs of extracellular vesicles derived from mesenchymal stromal cells alleviate inflammation in dry eye disease by targeting the IRAK1\/TAB2\/NF-\u03baB pathway"],"prefix":"10.1016","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4237-0865","authenticated-orcid":false,"given":"Leying","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueyao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiankun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenyu","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xizhan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deqiang","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuheng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiguo","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0000-3167","authenticated-orcid":false,"given":"Qingfeng","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtos.2023.03.002_bib1","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.jtos.2017.05.011","article-title":"TFOS DEWS II pathophysiology report","volume":"15","author":"Bron","year":"2017","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jtos.2023.03.002_bib2","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.ajo.2017.06.033","article-title":"Prevalence of diagnosed dry eye disease in the United States among adults aged 18 years and older","volume":"182","author":"Farrand","year":"2017","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jtos.2023.03.002_bib3","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.jtos.2017.05.003","article-title":"TFOS DEWS II epidemiology report","volume":"15","author":"Stapleton","year":"2017","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jtos.2023.03.002_bib4","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jtos.2021.08.002","article-title":"Relationship between screen time and dry eye symptoms in pediatric population during the COVID-19 pandemic","volume":"22","author":"Elhusseiny","year":"2021","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jtos.2023.03.002_bib5","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1097\/ICO.0000000000001216","article-title":"Patients' perceived treatment effectiveness in dry eye disease","volume":"36","author":"Kheirkhah","year":"2017","journal-title":"Cornea"},{"key":"10.1016\/j.jtos.2023.03.002_bib6","doi-asserted-by":"crossref","first-page":"3203","DOI":"10.1167\/iovs.08-2476","article-title":"Production and activity of matrix metalloproteinase-9 on the ocular surface increase in dysfunctional tear syndrome","volume":"50","author":"Chotikavanich","year":"2009","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2023.03.002_bib7","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.jtos.2017.05.006","article-title":"TFOS DEWS II management and therapy report","volume":"15","author":"Jones","year":"2017","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jtos.2023.03.002_bib8","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1111\/jgh.14081","article-title":"A study about immunomodulatory effect and efficacy and prognosis of human umbilical cord mesenchymal stem cells in patients with chronic hepatitis B-induced decompensated liver cirrhosis","volume":"33","author":"Fang","year":"2018","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.jtos.2023.03.002_bib9","doi-asserted-by":"crossref","first-page":"F31","DOI":"10.1152\/ajprenal.00007.2005","article-title":"Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms","volume":"289","author":"Togel","year":"2005","journal-title":"Am J Physiol Ren Physiol"},{"key":"10.1016\/j.jtos.2023.03.002_bib10","doi-asserted-by":"crossref","first-page":"2116","DOI":"10.1002\/stem.1481","article-title":"Transplantation of human umbilical mesenchymal stem cells cures the corneal defects of mucopolysaccharidosis VII mice","volume":"31","author":"Coulson-Thomas","year":"2013","journal-title":"Stem Cell"},{"key":"10.1016\/j.jtos.2023.03.002_bib11","article-title":"Role of mesenchymal stem cells on cornea wound healing induced by acute alkali burn","volume":"7","author":"Yao","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jtos.2023.03.002_bib12","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1111\/j.1755-3768.2009.01812.x","article-title":"Corneal surface reconstruction using adult mesenchymal stem cells in experimental limbal stem cell deficiency in rabbits","volume":"89","author":"Reinshagen","year":"2011","journal-title":"Acta Ophthalmol"},{"key":"10.1016\/j.jtos.2023.03.002_bib13","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1186\/s13287-018-1023-x","article-title":"Mesenchymal stem cell transplantation ameliorates Sjogren's syndrome via suppressing IL-12 production by dendritic cells","volume":"9","author":"Shi","year":"2018","journal-title":"Stem Cell Res Ther"},{"key":"10.1016\/j.jtos.2023.03.002_bib14","article-title":"Delivery of bone marrow-derived mesenchymal stem cells improves tear production in a mouse model of Sjogren's syndrome","volume":"2017","author":"Aluri","year":"2017","journal-title":"Stem Cell Int"},{"key":"10.1016\/j.jtos.2023.03.002_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2019.116733","article-title":"Human umbilical cord mesenchymal stem cells derived-exosomes in diseases treatment","volume":"233","author":"Yaghoubi","year":"2019","journal-title":"Life Sci"},{"key":"10.1016\/j.jtos.2023.03.002_bib16","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-54840-5","article-title":"MSC transplantation improves lacrimal gland regeneration after surgically induced dry eye disease in mice","volume":"9","author":"Dietrich","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.jtos.2023.03.002_bib17","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.3389\/fimmu.2020.01509","article-title":"Recent advances in the use of exosomes in Sjogren's syndrome","volume":"11","author":"Huang","year":"2020","journal-title":"Front Immunol"},{"key":"10.1016\/j.jtos.2023.03.002_bib18","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/scrt216","article-title":"Mesenchymal stem cells generate a CD4+CD25+Foxp3+ regulatory T cell population during the differentiation process of Th1 and Th17 cells","volume":"4","author":"Luz-Crawford","year":"2013","journal-title":"Stem Cell Res Ther"},{"key":"10.1016\/j.jtos.2023.03.002_bib19","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.stem.2012.03.007","article-title":"Mesenchymal-stem-cell-induced immunoregulation involves FAS-ligand-\/FAS-mediated T cell apoptosis","volume":"10","author":"Akiyama","year":"2012","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.jtos.2023.03.002_bib20","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.684712","article-title":"Mini review: current trends and understanding of exosome therapeutic potential in corneal diseases","volume":"12","author":"Tiwari","year":"2021","journal-title":"Front Pharmacol"},{"key":"10.1016\/j.jtos.2023.03.002_bib21","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1038\/s41581-018-0023-5","article-title":"Immunoregulatory mechanisms of mesenchymal stem and stromal cells in inflammatory diseases","volume":"14","author":"Shi","year":"2018","journal-title":"Nat Rev Nephrol"},{"key":"10.1016\/j.jtos.2023.03.002_bib22","doi-asserted-by":"crossref","first-page":"3365","DOI":"10.1242\/jcs.113.19.3365","article-title":"Exosome: from internal vesicle of the multivesicular body to intercellular signaling device","volume":"113 Pt 19","author":"Denzer","year":"2000","journal-title":"J Cell Sci"},{"key":"10.1016\/j.jtos.2023.03.002_bib23","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1042\/BST20180079","article-title":"MSC exosome works through a protein-based mechanism of action","volume":"46","author":"Toh","year":"2018","journal-title":"Biochem Soc Trans"},{"key":"10.1016\/j.jtos.2023.03.002_bib24","doi-asserted-by":"crossref","first-page":"5911","DOI":"10.2147\/IJN.S249129","article-title":"Umbilical cord-derived mesenchymal stem cell-derived exosomes combined pluronic F127 hydrogel promote chronic diabetic wound healing and complete skin regeneration","volume":"15","author":"Yang","year":"2020","journal-title":"Int J Nanomed"},{"key":"10.1016\/j.jtos.2023.03.002_bib25","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abj9617","article-title":"miR-204-containing exosomes ameliorate GVHD-associated dry eye disease","volume":"8","author":"Zhou","year":"2022","journal-title":"Sci Adv"},{"key":"10.1016\/j.jtos.2023.03.002_bib26","doi-asserted-by":"crossref","first-page":"5248","DOI":"10.7150\/thno.54550","article-title":"Exosomal miR-125b-5p deriving from mesenchymal stem cells promotes tubular repair by suppression of p53 in ischemic acute kidney injury","volume":"11","author":"Cao","year":"2021","journal-title":"Theranostics"},{"key":"10.1016\/j.jtos.2023.03.002_bib27","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/scrt194","article-title":"Exosomes released by human umbilical cord mesenchymal stem cells protect against cisplatin-induced renal oxidative stress and apoptosis in vivo and in vitro","volume":"4","author":"Zhou","year":"2013","journal-title":"Stem Cell Res Ther"},{"key":"10.1016\/j.jtos.2023.03.002_bib28","doi-asserted-by":"crossref","DOI":"10.1080\/20013078.2018.1535750","article-title":"Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines","volume":"7","author":"Thery","year":"2018","journal-title":"J Extracell Vesicles"},{"key":"10.1016\/j.jtos.2023.03.002_bib29","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1080\/02713683.2017.1297462","article-title":"Comparison of 0.3% hypotonic and isotonic sodium hyaluronate eye drops in the treatment of experimental dry eye","volume":"42","author":"Li","year":"2017","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.jtos.2023.03.002_bib30","doi-asserted-by":"crossref","first-page":"W521","DOI":"10.1093\/nar\/gkaa309","article-title":"miEAA 2.0: integrating multi-species microRNA enrichment analysis and workflow management systems","volume":"48","author":"Kern","year":"2020","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jtos.2023.03.002_bib31","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.05005","article-title":"Predicting effective microRNA target sites in mammalian mRNAs","volume":"4","author":"Agarwal","year":"2015","journal-title":"Elife"},{"key":"10.1016\/j.jtos.2023.03.002_bib32","article-title":"Dry eye disease in patients with schizophrenia: a case-control study","volume":"9","author":"Chen","year":"2022","journal-title":"Front Med (Lausanne)"},{"key":"10.1016\/j.jtos.2023.03.002_bib33","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.jcyt.2014.08.009","article-title":"Discarded Wharton jelly of the human umbilical cord: a viable source for mesenchymal stromal cells","volume":"17","author":"Watson","year":"2015","journal-title":"Cytotherapy"},{"key":"10.1016\/j.jtos.2023.03.002_bib34","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.3390\/cells8121605","article-title":"Mesenchymal stem cell-derived exosomes and other extracellular vesicles as new remedies in the therapy of inflammatory diseases","volume":"8","author":"Harrell","year":"2019","journal-title":"Cells"},{"key":"10.1016\/j.jtos.2023.03.002_bib35","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1186\/s13287-019-1372-0","article-title":"Recent advances of exosomes in immune-mediated eye diseases","volume":"10","author":"Li","year":"2019","journal-title":"Stem Cell Res Ther"},{"key":"10.1016\/j.jtos.2023.03.002_bib36","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.3390\/cells9102271","article-title":"Therapeutic miRNA-enriched extracellular vesicles: current approaches and future prospects","volume":"9","author":"Munir","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.jtos.2023.03.002_bib37","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.3390\/biom10091353","article-title":"MiRNA profiles of extracellular vesicles secreted by mesenchymal stromal cells-can they predict potential off-target effects?","volume":"10","author":"Nazari-Shafti","year":"2020","journal-title":"Biomolecules"},{"key":"10.1016\/j.jtos.2023.03.002_bib38","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1507\/endocrj.EJ20-0619","article-title":"Exosomes from mesenchymal stem cells expressing microribonucleic acid-125b inhibit the progression of diabetic nephropathy via the tumour necrosis factor receptor-associated factor 6\/Akt axis","volume":"68","author":"Cai","year":"2021","journal-title":"Endocr J"},{"key":"10.1016\/j.jtos.2023.03.002_bib39","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.14336\/AD.2021.0621","article-title":"Identification of molecules responsible for therapeutic effects of extracellular vesicles produced from iPSC-derived MSCs on Sjo gren's syndrome","volume":"12","author":"Kim","year":"2021","journal-title":"Aging Dis"},{"key":"10.1016\/j.jtos.2023.03.002_bib40","doi-asserted-by":"crossref","first-page":"6882","DOI":"10.1038\/s41598-019-42601-3","article-title":"MicroRNA-125b-5p regulates IL-1beta induced inflammatory genes via targeting TRAF6-mediated MAPKs and NF-kappaB signaling in human osteoarthritic chondrocytes","volume":"9","author":"Rasheed","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.jtos.2023.03.002_bib41","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1016\/j.ymthe.2020.04.020","article-title":"Comprehensive molecular profiles of functionally effective MSC-derived extracellular vesicles in immunomodulation","volume":"28","author":"Kim","year":"2020","journal-title":"Mol Ther"},{"key":"10.1016\/j.jtos.2023.03.002_bib42","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.neo.2018.06.004","article-title":"Snail-overexpressing cancer cells promote M2-like polarization of tumor-associated macrophages by delivering MiR-21-abundant exosomes","volume":"20","author":"Hsieh","year":"2018","journal-title":"Neoplasia"},{"key":"10.1016\/j.jtos.2023.03.002_bib43","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0056709","article-title":"Let-7b is involved in the inflammation and immune responses associated with Helicobacter pylori infection by targeting Toll-like receptor 4","volume":"8","author":"Teng","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jtos.2023.03.002_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2021.111419","article-title":"Kaempferol alleviates human endothelial cell injury through circNOL12\/miR-6873-3p\/FRS2 axis","volume":"137","author":"Li","year":"2021","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.jtos.2023.03.002_bib45","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.bbrc.2020.02.109","article-title":"Circular RNA circ-RELL1 regulates inflammatory response by miR-6873-3p\/MyD88\/NF-kappaB axis in endothelial cells","volume":"525","author":"Huang","year":"2020","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.jtos.2023.03.002_bib46","doi-asserted-by":"crossref","first-page":"10855","DOI":"10.1111\/jcmm.15714","article-title":"Curcumin reinforces MSC-derived exosomes in attenuating osteoarthritis via modulating the miR-124\/NF-kB and miR-143\/ROCK1\/TLR9 signalling pathways","volume":"24","author":"Qiu","year":"2020","journal-title":"J Cell Mol Med"},{"key":"10.1016\/j.jtos.2023.03.002_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.111048","article-title":"Mesenchymal stem cell-derived extracellular vesicles promote microglial M2 polarization after subarachnoid hemorrhage in rats and involve the AMPK\/NF-kappaB signaling pathway","volume":"133","author":"Han","year":"2021","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.jtos.2023.03.002_bib48","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.jtos.2012.04.001","article-title":"Nuclear factor-kappaB: central regulator in ocular surface inflammation and diseases","volume":"10","author":"Lan","year":"2012","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jtos.2023.03.002_bib49","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-71337-8","article-title":"hADSCs derived extracellular vesicles inhibit NLRP3inflammasome activation and dry eye","volume":"10","author":"Yu","year":"2020","journal-title":"Sci Rep"},{"key":"10.1016\/j.jtos.2023.03.002_bib50","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1159\/000519458","article-title":"Exosomes derived from mouse adipose-derived mesenchymal stem cells alleviate benzalkonium chloride-induced mouse dry eye model via inhibiting NLRP3 inflammasome","volume":"65","author":"Wang","year":"2022","journal-title":"Ophthalmic Res"},{"key":"10.1016\/j.jtos.2023.03.002_bib51","doi-asserted-by":"crossref","first-page":"3328","DOI":"10.3390\/ijms20133328","article-title":"The NLRP3 inflammasome: an overview of mechanisms of activation and regulation","volume":"20","author":"Kelley","year":"2019","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jtos.2023.03.002_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.retram.2021.103286","article-title":"Extracellular vesicles isolated from mesenchymal stromal cells primed with neurotrophic factors and signaling modifiers as potential therapeutics for eurodegenerative diseases","volume":"69","author":"Teli","year":"2021","journal-title":"Curr Res Transl Med"},{"key":"10.1016\/j.jtos.2023.03.002_bib53","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/s11658-022-00359-z","article-title":"Therapeutic utility of mesenchymal stromal cell (MSC)-based approaches in chronic neurodegeneration: a glimpse into underlying mechanisms, current status, and prospects","volume":"27","author":"Rahbaran","year":"2022","journal-title":"Cell Mol Biol Lett"},{"key":"10.1016\/j.jtos.2023.03.002_bib54","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.3390\/cells9051157","article-title":"Mesenchymal stem\/stromal cell-derived exosomes for immunomodulatory therapeutics and skin regeneration","volume":"9","author":"Ha","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.jtos.2023.03.002_bib55","article-title":"Potential role of corneal epithelial cell-derived exosomes in corneal wound healing and neovascularization","volume":"7","author":"Han","year":"2017","journal-title":"Sci Rep"}],"container-title":["The Ocular Surface"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542012423000241?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542012423000241?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T18:48:53Z","timestamp":1716403733000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1542012423000241"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":55,"alternative-id":["S1542012423000241"],"URL":"https:\/\/doi.org\/10.1016\/j.jtos.2023.03.002","relation":{},"ISSN":["1542-0124"],"issn-type":[{"value":"1542-0124","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"MicroRNAs of extracellular vesicles derived from mesenchymal stromal cells alleviate inflammation in dry eye disease by targeting the IRAK1\/TAB2\/NF-\u03baB pathway","name":"articletitle","label":"Article Title"},{"value":"The Ocular Surface","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtos.2023.03.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}