{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T12:09:46Z","timestamp":1793189386042,"version":"4.5.0"},"reference-count":69,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T00:00:00Z","timestamp":1736553600000},"content-version":"am","delay-in-days":285,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["PO1HL107147"],"award-info":[{"award-number":["PO1HL107147"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"publisher","award":["P30EY07551"],"award-info":[{"award-number":["P30EY07551"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"publisher","award":["R01EY029289"],"award-info":[{"award-number":["R01EY029289"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"publisher","award":["RO1EY033024"],"award-info":[{"award-number":["RO1EY033024"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Ocular Surface"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1016\/j.jtos.2023.12.007","type":"journal-article","created":{"date-parts":[[2023,12,25]],"date-time":"2023-12-25T18:28:54Z","timestamp":1703528934000},"page":"26-38","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Endogenous TSG-6 modulates corneal inflammation following chemical injury"],"prefix":"10.1016","volume":"32","author":[{"given":"Sudhir","family":"Verma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel Y.","family":"Moreno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cassio","family":"Prinholato da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingxia","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuhong","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarsis F.","family":"Gesteira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5848-0225","authenticated-orcid":false,"given":"Vivien J.","family":"Coulson- Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtos.2023.12.007_bib1","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1083\/jcb.116.2.545","article-title":"A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44","volume":"116","author":"Lee","year":"1992","journal-title":"JCB (J Cell Biol)"},{"key":"10.1016\/j.jtos.2023.12.007_bib2","doi-asserted-by":"crossref","DOI":"10.1074\/jbc.M115.710673","article-title":"Tumor necrosis factor-stimulated gene-6 (TSG-6) is constitutively expressed in adult central nervous system (CNS) and associated with astrocyte-mediated glial scar formation following spinal cord injury","volume":"291","author":"Coulson-Thomas","year":"2016","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jtos.2023.12.007_bib3","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/j.1468-3083.2010.03792.x","article-title":"Characterization of hyaluronan and TSG\u20106 in skin scarring: differential distribution in keloid scars, normal scars and unscarred skin","volume":"25","author":"Tan","year":"2011","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.jtos.2023.12.007_bib4","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1007\/s11892-012-0297-0","article-title":"The role of hyaluronan and the extracellular matrix in islet inflammation and immune regulation","volume":"12","author":"Bollyky","year":"2012","journal-title":"Curr Diab Rep"},{"key":"10.1016\/j.jtos.2023.12.007_bib5","doi-asserted-by":"crossref","first-page":"2727","DOI":"10.2337\/db13-1658","article-title":"Hyaluronan and hyaluronan-binding proteins accumulate in both human type 1 diabetic islets and lymphoid tissues and associate with inflammatory cells in insulitis","volume":"63","author":"Bogdani","year":"2014","journal-title":"Diabetes"},{"key":"10.1016\/j.jtos.2023.12.007_bib6","doi-asserted-by":"crossref","first-page":"12433","DOI":"10.1074\/jbc.M112.342873","article-title":"Constitutive expression of inter-\u03b1-inhibitor (I\u03b1I) family proteins and tumor necrosis factor-stimulated gene-6 (TSG-6) by human amniotic membrane epithelial and stromal cells supporting formation of the heavy chain-hyaluronan (HC-HA) complex","volume":"287","author":"Zhang","year":"2012","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jtos.2023.12.007_bib7","doi-asserted-by":"crossref","first-page":"23559","DOI":"10.1074\/jbc.M111.222026","article-title":"TSG-6 protein, a negative regulator of inflammatory arthritis, forms a ternary complex with murine mast cell tryptases and heparin","volume":"286","author":"Nagyeri","year":"2011","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jtos.2023.12.007_bib8","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1189\/jlb.0608345","article-title":"Coregulation in human leukocytes of the long pentraxin PTX3 and TSG-6","volume":"86","author":"Maina","year":"2009","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.jtos.2023.12.007_bib9","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1242\/jcs.00407","article-title":"TSG-6: a multifunctional protein associated with inflammation","volume":"116","author":"Milner","year":"2003","journal-title":"J Cell Sci"},{"key":"10.1016\/j.jtos.2023.12.007_bib10","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1074\/jbc.M112.389874","article-title":"TSG-6 protein is crucial for the development of pulmonary hyaluronan deposition, eosinophilia, and airway hyperresponsiveness in a murine model of asthma","volume":"288","author":"Swaidani","year":"2013","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jtos.2023.12.007_bib11","doi-asserted-by":"crossref","first-page":"6593","DOI":"10.4049\/jimmunol.151.11.6593","article-title":"TSG-6: a TNF-, IL-1-, and LPS-inducible secreted glycoprotein associated with arthritis","volume":"151","author":"Wisniewski","year":"1993","journal-title":"J Immunol"},{"key":"10.1016\/j.jtos.2023.12.007_bib12","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1002\/art.30201","article-title":"TSG-6 inhibits osteoclast activity via an autocrine mechanism and is functionally synergistic with osteoprotegerin","volume":"63","author":"Mahoney","year":"2011","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jtos.2023.12.007_bib13","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1161\/01.RES.81.3.289","article-title":"Growth factor and cytokine-regulated hyaluronan-binding protein TSG-6 is localized to the injury-induced rat neointima and confers enhanced growth in vascular smooth muscle cells","volume":"81","author":"Ye","year":"1997","journal-title":"Circ Res"},{"key":"10.1016\/j.jtos.2023.12.007_bib14","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S1359-6101(97)00008-7","article-title":"TSG-6: an IL-1\/TNF-inducible protein with anti-inflammatory activity","volume":"8","author":"Wisniewski","year":"1997","journal-title":"Cytokine Growth Factor Rev"},{"key":"10.1016\/j.jtos.2023.12.007_bib15","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.matbio.2018.01.011","article-title":"TSG-6: a multifunctional protein with anti-inflammatory and tissue-protective properties","volume":"78\u201379","author":"Day","year":"2019","journal-title":"Matrix Biol"},{"key":"10.1016\/j.jtos.2023.12.007_bib16","doi-asserted-by":"crossref","first-page":"16875","DOI":"10.1073\/pnas.1012451107","article-title":"Anti-inflammatory protein TSG-6 reduces inflammatory damage to the cornea following chemical and mechanical injury","volume":"107","author":"Oh","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jtos.2023.12.007_bib17","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1042\/BST0340446","article-title":"TSG-6: a pluripotent inflammatory mediator?","volume":"34","author":"Milner","year":"2006","journal-title":"Biochem Soc Trans"},{"key":"10.1016\/j.jtos.2023.12.007_bib18","doi-asserted-by":"crossref","first-page":"51068","DOI":"10.1074\/jbc.M205121200","article-title":"The Link module from human TSG-6 inhibits neutrophil migration in a hyaluronan- and inter-\u03b1-inhibitor-independent manner","volume":"277","author":"Getting","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jtos.2023.12.007_bib19","doi-asserted-by":"crossref","first-page":"3012","DOI":"10.1002\/art.20655","article-title":"Enhanced neutrophil extravasation and rapid progression of proteoglycan-induced arthritis in TSG-6-knockout mice","volume":"50","author":"Sz\u00e1nt\u00f3","year":"2004","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jtos.2023.12.007_bib20","doi-asserted-by":"crossref","first-page":"2668","DOI":"10.1002\/1529-0131(200012)43:12<2668::AID-ANR6>3.0.CO;2-E","article-title":"Amelioration of collagen-induced arthritis in DBA\/1J mice by recombinant TSG-6, a tumor necrosis factor\/interleukin-1-inducible protein","volume":"43","author":"Mindrescu","year":"2000","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jtos.2023.12.007_bib21","doi-asserted-by":"crossref","first-page":"2453","DOI":"10.1002\/art.10503","article-title":"Reduced susceptibility to collagen-induced arthritis in DBA\/1J mice expressing the TSG-6 transgene","volume":"46","author":"Mindrescu","year":"2002","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jtos.2023.12.007_bib22","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/s12865-021-00443-7","article-title":"Anti-inflammatory protein TNF\u03b1-stimulated gene-6 (TSG-6) reduces inflammatory response after brain injury in mice","volume":"22","author":"Mutoji","year":"2021","journal-title":"BMC Immunol"},{"key":"10.1016\/j.jtos.2023.12.007_bib23","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.nbd.2013.06.017","article-title":"Administration of TSG-6 improves memory after traumatic brain injury in mice","volume":"59","author":"Watanabe","year":"2013","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.jtos.2023.12.007_bib24","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.stem.2009.05.003","article-title":"Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6","volume":"5","author":"Lee","year":"2009","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.jtos.2023.12.007_bib25","doi-asserted-by":"crossref","first-page":"25952","DOI":"10.1074\/jbc.M802138200","article-title":"TSG-6 regulates bone remodeling through inhibition of osteoblastogenesis and osteoclast activation","volume":"283","author":"Mahoney","year":"2008","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jtos.2023.12.007_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110266","article-title":"Inhibitory effect of the TSG-6 on the BMP-4\/Smad signaling pathway and odonto\/osteogenic differentiation of dental pulp stem cells","volume":"128","author":"Wang","year":"2020","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.jtos.2023.12.007_bib27","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1007\/s00441-017-2581-4","article-title":"TSG-6 secreted by mesenchymal stem cells suppresses immune reactions influenced by BMP-2 through p38 and MEK mitogen-activated protein kinase pathway","volume":"368","author":"Um","year":"2017","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.jtos.2023.12.007_bib28","doi-asserted-by":"crossref","first-page":"2177","DOI":"10.4049\/jimmunol.1300194","article-title":"TSG-6 inhibits neutrophil migration via direct interaction with the chemokine CXCL8","volume":"192","author":"Dyer","year":"2014","journal-title":"J Immunol"},{"key":"10.1016\/j.jtos.2023.12.007_bib29","doi-asserted-by":"crossref","first-page":"12627","DOI":"10.1074\/jbc.M116.720953","article-title":"The anti-inflammatory protein TSG-6 regulates chemokine function by inhibiting chemokine\/glycosaminoglycan interactions","volume":"291","author":"Dyer","year":"2016","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jtos.2023.12.007_bib30","doi-asserted-by":"crossref","first-page":"36","DOI":"10.7150\/thno.37301","article-title":"Liver-targeted delivery of TSG-6 by calcium phosphate nanoparticles for the management of liver fibrosis","volume":"10","author":"Wang","year":"2020","journal-title":"Theranostics"},{"key":"10.1016\/j.jtos.2023.12.007_bib31","doi-asserted-by":"crossref","first-page":"E8151","DOI":"10.1073\/pnas.1614935113","article-title":"TNF\u03b1-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury","volume":"113","author":"Mittal","year":"2016","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jtos.2023.12.007_bib32","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1186\/s12974-018-1279-1","article-title":"TSG-6 attenuates inflammation-induced brain injury via modulation of microglial polarization in SAH rats through the SOCS3\/STAT3 pathway","volume":"15","author":"Li","year":"2018","journal-title":"J Neuroinflammation"},{"key":"10.1016\/j.jtos.2023.12.007_bib33","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1053\/j.gastro.2015.03.013","article-title":"Mesenchymal stem cells reduce colitis in mice via release of TSG6, independently of their localization to the intestine","volume":"149","author":"Sala","year":"2015","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jtos.2023.12.007_bib34","doi-asserted-by":"crossref","first-page":"5175","DOI":"10.1167\/iovs.14-16307","article-title":"Topical TSG-6 administration protects the ocular surface in two mouse models of inflammation-related dry eye","volume":"56","author":"Lee","year":"2015","journal-title":"Investig Opthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2023.12.007_bib35","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jtos.2021.12.012","article-title":"The Link module of human TSG-6 (Link_TSG6) promotes wound healing, suppresses inflammation and improves glandular function in mouse models of Dry Eye Disease","volume":"24","author":"Oh","year":"2022","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jtos.2023.12.007_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.joca.2023.05.013","article-title":"The recombinant Link module of human TSG-6 suppresses cartilage damage in models of osteoarthritis: a potential disease-modifying OA drug","author":"Drummond","year":"2023","journal-title":"Osteoarth Cartil"},{"key":"10.1016\/j.jtos.2023.12.007_bib37","doi-asserted-by":"crossref","first-page":"5619","DOI":"10.1074\/jbc.M113.542357","article-title":"A refined model for the TSG-6 Link module in complex with hyaluronan","volume":"289","author":"Higman","year":"2014","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jtos.2023.12.007_bib38","doi-asserted-by":"crossref","DOI":"10.3390\/biom10111525","article-title":"Hyaluronan: metabolism and function","volume":"10","author":"Kobayashi","year":"2020","journal-title":"Biomolecules"},{"key":"10.1016\/j.jtos.2023.12.007_bib39","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.carbpol.2016.07.125","article-title":"Is molecular size a discriminating factor in hyaluronan interaction with human cells?","volume":"157","author":"D'Agostino","year":"2017","journal-title":"Carbohydr Polym"},{"key":"10.1016\/j.jtos.2023.12.007_bib40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/bs.accb.2017.10.001","article-title":"Hyaluronan and hyaluronan fragments","volume":"74","author":"Cowman","year":"2017","journal-title":"Adv Carbohydr Chem Biochem"},{"key":"10.1016\/j.jtos.2023.12.007_bib41","doi-asserted-by":"crossref","first-page":"2452","DOI":"10.1016\/j.bbagen.2014.02.001","article-title":"Hyaluronan: biosynthesis and signaling","volume":"1840","author":"Vigetti","year":"2014","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.jtos.2023.12.007_bib42","doi-asserted-by":"crossref","first-page":"25675","DOI":"10.1074\/jbc.M111.247395","article-title":"The inflammation-associated protein TSG-6 cross-links hyaluronan via hyaluronan-induced TSG-6 oligomers","volume":"286","author":"Baranova","year":"2011","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jtos.2023.12.007_bib43","doi-asserted-by":"crossref","first-page":"25745","DOI":"10.1074\/jbc.M313319200","article-title":"TSG-6 modulates the interaction between hyaluronan and cell surface CD44","volume":"279","author":"Lesley","year":"2004","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jtos.2023.12.007_bib44","doi-asserted-by":"crossref","first-page":"28708","DOI":"10.1074\/jbc.M115.669838","article-title":"Metal ion-dependent heavy chain transfer activity of TSG-6 mediates assembly of the cumulus-oocyte matrix","volume":"290","author":"Briggs","year":"2015","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jtos.2023.12.007_bib45","doi-asserted-by":"crossref","first-page":"25674","DOI":"10.1074\/jbc.M501332200","article-title":"Characterization of complexes formed between TSG-6 andInter-\u03b1-inhibitor that act as intermediates in the covalent transfer of heavy chains onto Hyaluronan","volume":"280","author":"Rugg","year":"2005","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jtos.2023.12.007_bib46","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1167\/iovs.64.13.48","article-title":"Characterization of the limbal epithelial stem cell niche","volume":"64","author":"Moreno","year":"2023","journal-title":"Investig Opthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2023.12.007_bib47","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.jtos.2021.03.010","article-title":"A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells","volume":"21","author":"Collin","year":"2021","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jtos.2023.12.007_bib48","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1167\/iovs.63.13.6","article-title":"Hyaluronan modulates the biomechanical properties of the cornea","volume":"63","author":"Lin","year":"2022","journal-title":"Investig Opthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2023.12.007_bib49","doi-asserted-by":"crossref","first-page":"23465","DOI":"10.1074\/jbc.M114.557447","article-title":"Umbilical cord mesenchymal stem cells suppress host rejection","volume":"289","author":"Coulson-Thomas","year":"2014","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jtos.2023.12.007_bib50","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1095\/biolreprod65.1.301","article-title":"TSG-6 is concentrated in the extracellular matrix of mouse cumulus oocyte complexes through hyaluronan and inter-alpha-inhibitor Binding1","volume":"65","author":"Carrette","year":"2001","journal-title":"Biol Reprod"},{"key":"10.1016\/j.jtos.2023.12.007_bib51","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1016\/S0002-9440(10)62575-8","article-title":"Induction of the hyaluronic acid-binding protein, tumor necrosis factor-stimulated gene-6, in cervical smooth muscle cells by tumor necrosis factor-\u03b1 and prostaglandin E2","volume":"160","author":"Fujimoto","year":"2002","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jtos.2023.12.007_bib52","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1186\/s13287-022-03084-8","article-title":"Hyaluronan supports the limbal stem cell phenotype during ex vivo culture","volume":"13","author":"Puri","year":"2022","journal-title":"Stem Cell Res Ther"},{"key":"10.1016\/j.jtos.2023.12.007_bib53","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1167\/iovs.04-0528","article-title":"Characterization of growth and differentiation in a telomerase-immortalized human corneal epithelial cell line","volume":"46","author":"Robertson","year":"2005","journal-title":"Investig Opthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2023.12.007_bib54","doi-asserted-by":"crossref","DOI":"10.1038\/srep42057","article-title":"Lumican peptides: rational design targeting ALK5\/TGFBRI","volume":"7","author":"Gesteira","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.jtos.2023.12.007_bib55","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.jtos.2023.09.007","article-title":"Rational design and synthesis of lumican stapled peptides for promoting corneal wound healing","author":"Verma","year":"2023","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jtos.2023.12.007_bib56","series-title":"Characterization of the limbal epithelial stem cell niche","author":"Moreno","year":"2023"},{"key":"10.1016\/j.jtos.2023.12.007_bib57","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1167\/iovs.18-25920","article-title":"Hyaluronan derived from the limbus is a key regulator of corneal lymphangiogenesis","volume":"60","author":"Sun","year":"2019","journal-title":"Investig Opthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2023.12.007_bib58","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1002\/emmm.201200221","article-title":"Identification of the HSPB4\/TLR2\/NF\u2010\u03baB axis in macrophage as a therapeutic target for sterile inflammation of the cornea","volume":"4","author":"Oh","year":"2012","journal-title":"EMBO Mol Med"},{"key":"10.1016\/j.jtos.2023.12.007_bib59","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.exer.2014.01.004","article-title":"Integrin-dependent neutrophil migration in the injured mouse cornea","volume":"120","author":"Hanlon","year":"2014","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.jtos.2023.12.007_bib60","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1369\/0022155412457048","article-title":"Hyaluronan and hyaluronan binding proteins are normal components of mouse pancreatic islets and are differentially expressed by islet endocrine cell types","volume":"60","author":"Hull","year":"2012","journal-title":"J Histochem Cytochem"},{"key":"10.1016\/j.jtos.2023.12.007_bib61","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/j.jfo.2020.03.005","article-title":"Detection of TSG-6-like protein in human corneal epithelium. Simultaneous presence with CD44 and hyaluronic acid","volume":"43","author":"Lardner","year":"2020","journal-title":"J Fr Ophtalmol"},{"key":"10.1016\/j.jtos.2023.12.007_bib62","doi-asserted-by":"crossref","first-page":"4407","DOI":"10.1167\/iovs.17-22326","article-title":"Hyaluronan rich microenvironment in the limbal stem cell niche regulates limbal stem cell differentiation","volume":"58","author":"Gesteira","year":"2017","journal-title":"Investig Opthalmol Vis Sci"},{"key":"10.1016\/j.jtos.2023.12.007_bib63","doi-asserted-by":"crossref","first-page":"5708","DOI":"10.3390\/ijms22115708","article-title":"Extracellular matrix deposition and remodeling after corneal alkali burn in mice","volume":"22","author":"Mutoji","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jtos.2023.12.007_bib64","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.exer.2008.08.013","article-title":"BALB\/c and C57BL6 mouse strains vary in their ability to heal corneal epithelial debridement wounds","volume":"87","author":"Pal-Ghosh","year":"2008","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.jtos.2023.12.007_bib65","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1080\/02713683.2019.1597893","article-title":"Absence of therapeutic benefit of the anti-inflammatory protein TSG-6 for corneal alkali injury in a rat model","volume":"44","author":"Choi","year":"2019","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.jtos.2023.12.007_bib66","doi-asserted-by":"crossref","first-page":"3329","DOI":"10.3390\/ijms24043329","article-title":"Inflammation confers healing advantage to corneal epithelium following subsequent injury","volume":"24","author":"Ryu","year":"2023","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jtos.2023.12.007_bib67","series-title":"Management of traumatic cataract","author":"Zamora-de la Cruz","year":"2016"},{"key":"10.1016\/j.jtos.2023.12.007_bib68","doi-asserted-by":"crossref","first-page":"2687","DOI":"10.2147\/OPTH.S235873","article-title":"Management strategies of ocular chemical burns: current perspectives","volume":"14","author":"Soleimani","year":"2020","journal-title":"Clin Ophthalmol"},{"key":"10.1016\/j.jtos.2023.12.007_bib69","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2014\/196827","article-title":"The ocular surface chemical burns","volume":"2014","author":"Eslani","year":"2014","journal-title":"J Ophthalmol"}],"container-title":["The Ocular Surface"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542012423001581?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542012423001581?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T04:48:43Z","timestamp":1761540523000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1542012423001581"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":69,"alternative-id":["S1542012423001581"],"URL":"https:\/\/doi.org\/10.1016\/j.jtos.2023.12.007","relation":{},"ISSN":["1542-0124"],"issn-type":[{"value":"1542-0124","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Endogenous TSG-6 modulates corneal inflammation following chemical injury","name":"articletitle","label":"Article Title"},{"value":"The Ocular Surface","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtos.2023.12.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}