{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T21:04:21Z","timestamp":1784927061017,"version":"3.55.0"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2008,5,1]],"date-time":"2008-05-01T00:00:00Z","timestamp":1209600000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Urology"],"published-print":{"date-parts":[[2008,5]]},"DOI":"10.1016\/j.juro.2008.01.047","type":"journal-article","created":{"date-parts":[[2008,3,19]],"date-time":"2008-03-19T08:43:36Z","timestamp":1205916216000},"page":"1850-1856","source":"Crossref","is-referenced-by-count":65,"title":["Urine Markers Do Not Predict Biopsy Findings or Presence of Bladder Ulcers in Interstitial Cystitis\/Painful Bladder Syndrome"],"prefix":"10.1097","volume":"179","author":[{"given":"Deborah R.","family":"Erickson","sequence":"first","affiliation":[{"name":"Department of Surgery, Division of Urology, University of Kentucky College of Medicine, Lexington, Kentucky"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John E.","family":"Tomaszewski","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Pennsylvania School of Medicine, Philadelphia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allen R.","family":"Kunselman","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina M.","family":"Stetter","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth M.","family":"Peters","sequence":"additional","affiliation":[{"name":"Department of Urology, William Beaumont Hospital, Royal Oak, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric S.","family":"Rovner","sequence":"additional","affiliation":[{"name":"Department of Urology, Medical University of South Carolina, Charleston, South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence M.","family":"Demers","sequence":"additional","affiliation":[{"name":"Departments of Pathology and Medicine, Pennsylvania State University College of Medicine, Hershey, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcia A.","family":"Wheeler","sequence":"additional","affiliation":[{"name":"Department of Surgery, Section of Urology, Yale University School of Medicine, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan K.","family":"Keay","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Infectious Diseases, University of Maryland School of Medicine and VA Medical Center, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"10.1016\/j.juro.2008.01.047_bib1","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1097\/01.ju.0000146466.71311.ab","article-title":"Do the National Institute of Diabetes and Digestive and Kidney Diseases cystoscopic criteria associate with other clinical and objective features of interstitial cystitis?","volume":"173","author":"Erickson","year":"2005","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2008.01.047_bib2","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/S0022-5347(01)61948-7","article-title":"The diagnosis of interstitial cystitis revisited: lessons learned from the National Institutes of Health Interstitial Cystitis Database Study","volume":"161","author":"Hanno","year":"1999","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2008.01.047_bib3","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1016\/S0022-5347(05)65005-7","article-title":"A comparison of multiple urine markers for interstitial cystitis","volume":"167","author":"Erickson","year":"2002","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2008.01.047_bib4","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0090-4295(01)01166-9","article-title":"Biopsy features are associated with primary symptoms in interstitial cystitis: results from the interstitial cystitis database study","volume":"57","author":"Tomaszewski","year":"2001","journal-title":"Urology"},{"key":"10.1016\/j.juro.2008.01.047_bib5","doi-asserted-by":"crossref","first-page":"2470","DOI":"10.1016\/S0022-5347(05)65006-9","article-title":"Toward a precise definition of interstitial cystitis: further evidence of differences in classic and nonulcer disease","volume":"167","author":"Peeker","year":"2002","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2008.01.047_bib6","doi-asserted-by":"crossref","first-page":"2748","DOI":"10.1172\/JCI24274","article-title":"Mast cell CD30 ligand is upregulated in cutaneous inflammation and mediates degranulation-independent chemokine secretion","volume":"116","author":"Fischer","year":"2006","journal-title":"J Clin Invest"},{"key":"10.1016\/j.juro.2008.01.047_bib7","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/S0022-5347(05)64750-7","article-title":"Mast cell activation triggers a urothelial inflammatory response mediated by tumor necrosis factor-alpha","volume":"168","author":"Batler","year":"2002","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2008.01.047_bib8","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1111\/j.1440-1681.1992.tb00402.x","article-title":"Origin of urinary epidermal growth factor in humans: excretion of endogenous EGF and infused [131I]-human EGF and kidney histochemistry","volume":"19","author":"Lev-Ran","year":"1992","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"10.1016\/j.juro.2008.01.047_bib9","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/BF02405045","article-title":"Salmon calcitonin and cGMP production by human kidney: studies in vivo and in vitro","volume":"35","author":"Gennari","year":"1983","journal-title":"Calcif Tissue Int"},{"key":"10.1016\/j.juro.2008.01.047_bib10","doi-asserted-by":"crossref","first-page":"2261","DOI":"10.1097\/01.ju.0000144761.69398.be","article-title":"Nitric oxide as an objective marker for evaluation of treatment response in patients with classic interstitial cystitis","volume":"172","author":"Hosseini","year":"2004","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2008.01.047_bib11","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1152\/physiolgenomics.00055.2003","article-title":"Changes in human bladder epithelial cell gene expression associated with interstitial cystitis or antiproliferative factor treatment","volume":"14","author":"Keay","year":"2003","journal-title":"Physiol Genomics"},{"key":"10.1016\/j.juro.2008.01.047_bib12","doi-asserted-by":"crossref","first-page":"2382","DOI":"10.1097\/01.ju.0000180417.11976.99","article-title":"Regulation of tight junction proteins and bladder epithelial paracellular permeability by an antiproliferative factor from patients with interstitial cystitis","volume":"174","author":"Zhang","year":"2005","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2008.01.047_bib13","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1016\/S0022-5347(05)66980-7","article-title":"Bladder epithelial cells from patients with interstitial cystitis produce an inhibitor of heparin-binding epidermal growth factor-like growth factor production","volume":"164","author":"Keay","year":"2000","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2008.01.047_bib14","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1097\/01.ju.0000118938.09119.a5","article-title":"Abnormal expression of molecular markers for bladder impermeability and differentiation in the urothelium of patients with interstitial cystitis","volume":"171","author":"Slobodov","year":"2004","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2008.01.047_bib15","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0090-4295(99)80329-X","article-title":"Interstitial cystitis: a critique of current concepts with a new proposal for pathologic diagnosis and pathogenesis","volume":"49","author":"Elbadawi","year":"1997","journal-title":"Urology"},{"key":"10.1016\/j.juro.2008.01.047_bib16","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1016\/j.juro.2007.05.125","article-title":"Uroplakin III-delta4 messenger RNA as a promising marker to identify nonulcerative interstitial cystitis","volume":"178","author":"Zeng","year":"2007","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2008.01.047_bib17","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/BF02222214","article-title":"Histamine and mucosal mast cells in interstitial cystitis","volume":"27","author":"Enerback","year":"1989","journal-title":"Agents Actions"},{"key":"10.1016\/j.juro.2008.01.047_bib18","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1471-2490-5-7","article-title":"APF, HB-EGF, and EGF biomarkers in patients with ulcerative vs. non-ulcerative interstitial cystitis","volume":"5","author":"Zhang","year":"2005","journal-title":"BMC Urol"},{"key":"10.1016\/j.juro.2008.01.047_bib19","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/S0022-5347(05)66093-4","article-title":"Use of the neodymium: YAG laser for interstitial cystitis: a prospective study","volume":"166","author":"Rofeim","year":"2001","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2008.01.047_bib20","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1097\/01.ju.0000153612.14639.19","article-title":"Efficacy of prednisone for severe refractory ulcerative interstitial cystitis","volume":"173","author":"Soucy","year":"2005","journal-title":"J Urol"}],"container-title":["Journal of Urology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0022534708000906?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0022534708000906?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.jurology.com\/doi\/pdf\/10.1016\/j.juro.2008.01.047","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T20:11:46Z","timestamp":1784923906000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.1016\/j.juro.2008.01.047"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["10.1016\/j.juro.2008.01.047"],"URL":"https:\/\/doi.org\/10.1016\/j.juro.2008.01.047","relation":{},"ISSN":["0022-5347","1527-3792"],"issn-type":[{"value":"0022-5347","type":"print"},{"value":"1527-3792","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,5]]}}}