{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T11:03:14Z","timestamp":1790420594223,"version":"4.1.0"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Urology"],"published-print":{"date-parts":[[2008,7]]},"DOI":"10.1016\/j.juro.2008.03.038","type":"journal-article","created":{"date-parts":[[2008,5,16]],"date-time":"2008-05-16T16:36:14Z","timestamp":1210955774000},"page":"110-115","source":"Crossref","is-referenced-by-count":58,"title":["Can Early Single Dose Instillation of Epirubicin Improve Bacillus Calmette-Guerin Efficacy in Patients With Nonmuscle Invasive High Risk Bladder Cancer? Results From a Prospective, Randomized, Double-Blind Controlled Study"],"prefix":"10.1097","volume":"180","author":[{"given":"Tommaso","family":"Cai","sequence":"first","affiliation":[{"name":"Department of Urology, University of Florence, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriella","family":"Nesi","sequence":"additional","affiliation":[{"name":"Department of Pathology and Oncology, University of Florence, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Galliano","family":"Tinacci","sequence":"additional","affiliation":[{"name":"Department of Pathology, Santa Maria Annunziata Hospital, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enzo","family":"Zini","sequence":"additional","affiliation":[{"name":"Department of Pathology, Santa Maria Annunziata Hospital, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Mondaini","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Florence, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vieri","family":"Boddi","sequence":"additional","affiliation":[{"name":"Department of Public Health and Epidemiology, University of Florence, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Mazzoli","sequence":"additional","affiliation":[{"name":"STDs Center, Santa Maria Annunziata Hospital, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Bartoletti","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Florence, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"10.1016\/j.juro.2008.03.038_bib1","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3322\/canjclin.57.1.43","article-title":"Cancer statistics, 2007","volume":"57","author":"Jemal","year":"2007","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.juro.2008.03.038_bib2","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.eururo.2005.12.031","article-title":"Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables: a combined analysis of 2596 patients from seven EORTC trials","volume":"49","author":"Sylvester","year":"2006","journal-title":"Eur Urol"},{"key":"10.1016\/j.juro.2008.03.038_bib3","doi-asserted-by":"crossref","first-page":"2186","DOI":"10.1097\/01.ju.0000125486.92260.b2","article-title":"A single immediate postoperative instillation of chemotherapy decreases the risk of recurrence in patients with stage Ta T1 bladder cancer: a meta-analysis of published results of randomized clinical trials","volume":"171","author":"Sylvester","year":"2004","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2008.03.038_bib4","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0302-2838(01)00026-4","article-title":"Guidelines on bladder cancer","volume":"41","author":"Oosterlinck","year":"2002","journal-title":"Eur Urol"},{"key":"10.1016\/j.juro.2008.03.038_bib5","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/S0022-5347(05)65966-6","volume":"166","author":"van der Meijden","year":"2001","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2008.03.038_bib6","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1046\/j.1464-410x.2001.02306.x","article-title":"A systematic review of intravesical bacillus Calmette-Gu\u00e9rin plus transurethral resection vs transhuretral resection alone in Ta and T1 bladder cancer","volume":"88","author":"Shelley","year":"2001","journal-title":"BJU Int"},{"key":"10.1016\/j.juro.2008.03.038_bib7","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.urology.2006.01.041","article-title":"The management of superficial transitional cell carcinoma of the bladder","volume":"67","author":"Segupta","year":"2006","journal-title":"Urology"},{"key":"10.1016\/j.juro.2008.03.038_bib8","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0302-2838(02)00260-9","article-title":"Factors explaining recurrence in patients undergoing chemoimmunotherapy regimens for frequently recurring superficial bladder carcinoma","volume":"42","author":"Kaasinen","year":"2002","journal-title":"Eur Urol"},{"key":"10.1016\/j.juro.2008.03.038_bib9","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0022-5347(05)67446-0","article-title":"Alternating mitomycin C and bacillus Calmette-Guerin instillation prophylaxis for recurrent papillary (stages Ta to T1) superficial bladder cancer","volume":"164","author":"Rintala","year":"2000","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2008.03.038_bib10","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/S0302-2838(03)00140-4","article-title":"Alternating mitomycin C and BCG instillations versus BCG alone in treatment of carcinoma in situ of the urinary bladder: a nordic study","volume":"43","author":"Kaasinen","year":"2003","journal-title":"Eur Urol"},{"key":"10.1016\/j.juro.2008.03.038_bib11","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1016\/S0022-5347(01)61606-9","article-title":"Effectiveness of a single immediate mitomycin C instillation in patients with low risk superficial bladder cancer: short and long-term followup","volume":"161","author":"Solsona","year":"1999","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2008.03.038_bib12","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/S0022-5347(17)36198-0","volume":"149","author":"Oosterlinck","year":"1993","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2008.03.038_bib13","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1097\/01.ju.0000056727.30546.b7","article-title":"Patterns of care for the treatment of bladder cancer","volume":"169","author":"Snyder","year":"2003","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2008.03.038_bib14","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.urolonc.2007.05.002","article-title":"Difficult decisions in urologic oncology: management of high-grade T1 transitional cell carcinoma of the bladder","volume":"25","author":"Soloway","year":"2007","journal-title":"Urol Oncol"},{"key":"10.1016\/j.juro.2008.03.038_bib15","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/S0022-5347(05)67707-5","article-title":"Maintenance BCG immunotherapy for recurrent Ta, T1 and Tis transitional cell carcinoma of the bladder: a randomized prospective Southwest Oncology Group study","volume":"163","author":"Lamm","year":"2000","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2008.03.038_bib16","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1016\/S0022-5347(05)68208-0","article-title":"Bladder cancer clinical guidelines panel summary report on the management of non-invasive bladder cancer (stage Ta, T1 and TIS)","volume":"162","author":"Smith","year":"1999","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2008.03.038_bib17","series-title":"Biostatistical Analysis","author":"Zar","year":"1974"},{"key":"10.1016\/j.juro.2008.03.038_bib18","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.eururo.2004.05.003","article-title":"One immediate postoperative instillation of chemotherapy in low risk Ta, T1 bladder cancer patients","volume":"46","author":"Oddens","year":"2004","journal-title":"Eur Urol"},{"key":"10.1016\/j.juro.2008.03.038_bib19","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1097\/01.ju.0000100386.07370.0a","article-title":"A randomized controlled trial of short-term versus long-term prophylactic intravesical instillation chemotherapy for recurrence after transurethral resection of Ta\/T1 transitional cell carcinoma of the bladder","volume":"171","author":"Koga","year":"2004","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2008.03.038_bib20","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/S0022-5347(05)64556-9","article-title":"Perioperative single dose instillation of epirubicin or interferon-alpha after transurethral resection for the prophylaxis of primary superficial bladder cancer recurrencea prospective randomized multicenter study\u2013FinnBladder III long-term results","volume":"168","author":"Rajala","year":"2002","journal-title":"J Urol"}],"container-title":["Journal of Urology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0022534708005958?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0022534708005958?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.jurology.com\/doi\/pdf\/10.1016\/j.juro.2008.03.038","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T01:27:11Z","timestamp":1651195631000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jurology.com\/doi\/10.1016\/j.juro.2008.03.038"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,7]]}},"alternative-id":["10.1016\/j.juro.2008.03.038"],"URL":"https:\/\/doi.org\/10.1016\/j.juro.2008.03.038","relation":{},"ISSN":["0022-5347","1527-3792"],"issn-type":[{"value":"0022-5347","type":"print"},{"value":"1527-3792","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,7]]}}}