{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T20:12:12Z","timestamp":1760645532829},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Urology"],"published-print":{"date-parts":[[2008,8]]},"DOI":"10.1016\/j.juro.2008.03.188","type":"journal-article","created":{"date-parts":[[2008,6,14]],"date-time":"2008-06-14T08:32:43Z","timestamp":1213432363000},"page":"772-776","source":"Crossref","is-referenced-by-count":12,"title":["The Vasodilator Effect of Testosterone on the Human Internal Spermatic Vein and its Relation to Varicocele Grade"],"prefix":"10.1097","volume":"180","author":[{"given":"Hasan Cem","family":"Irkilata","sequence":"first","affiliation":[{"name":"Departments of Urology and Pharmacology (OY, MS), School of Medicine, Gulhane Military Medical Academy, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oguzhan","family":"Yildiz","sequence":"additional","affiliation":[{"name":"Departments of Urology and Pharmacology (OY, MS), School of Medicine, Gulhane Military Medical Academy, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrahim","family":"Yildirim","sequence":"additional","affiliation":[{"name":"Departments of Urology and Pharmacology (OY, MS), School of Medicine, Gulhane Military Medical Academy, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melik","family":"Seyrek","sequence":"additional","affiliation":[{"name":"Departments of Urology and Pharmacology (OY, MS), School of Medicine, Gulhane Military Medical Academy, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seref","family":"Basal","sequence":"additional","affiliation":[{"name":"Departments of Urology and Pharmacology (OY, MS), School of Medicine, Gulhane Military Medical Academy, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat","family":"Dayanc","sequence":"additional","affiliation":[{"name":"Departments of Urology and Pharmacology (OY, MS), School of Medicine, Gulhane Military Medical Academy, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cunay","family":"Ulku","sequence":"additional","affiliation":[{"name":"Departments of Urology and Pharmacology (OY, MS), School of Medicine, Gulhane Military Medical Academy, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"10.1016\/j.juro.2008.03.188_bib1","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1210\/jcem-27-5-686","volume":"27","author":"Southren","year":"1967","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.juro.2008.03.188_bib2","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/S0094-0143(02)00075-7","article-title":"Varicocele: current concepts in pathophysiology, diagnosis, and treatment","volume":"29","author":"Fretz","year":"2002","journal-title":"Urol Clin North Am"},{"key":"10.1016\/j.juro.2008.03.188_bib3","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/s00240-003-0343-0","article-title":"Increased vasoconstrictor reactivity and decreased endothelial function in high grade varicocele: functional and morphological study","volume":"31","author":"Yildiz","year":"2003","journal-title":"Urol Res"},{"key":"10.1016\/j.juro.2008.03.188_bib4","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.1210\/me.2002-0070","article-title":"The roles of androgen receptors and androgen-binding proteins in nongenomic androgen actions","volume":"16","author":"Heinlein","year":"2002","journal-title":"Mol Endocrinol"},{"key":"10.1016\/j.juro.2008.03.188_bib5","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1161\/01.CIR.91.4.1154","article-title":"Testosterone relaxes rabbit coronary arteries and aorta","volume":"91","author":"Yue","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.juro.2008.03.188_bib6","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1097\/00005344-200206000-00006","article-title":"Pulmonary vasodilatory action of testosterone: evidence of a calcium antagonistic action","volume":"39","author":"Jones","year":"2002","journal-title":"J Cardiovasc Pharmacol"},{"key":"10.1016\/j.juro.2008.03.188_bib7","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1254\/jphs.FP0060883","article-title":"Testosterone relaxes isolated human radial artery by potassium channel opening action","volume":"103","author":"Seyrek","year":"2007","journal-title":"J Pharmacol Sci"},{"key":"10.1016\/j.juro.2008.03.188_bib8","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1097\/01.fjc.0000161400.06704.1e","article-title":"Testosterone relaxes human internal mammary artery in vitro","volume":"45","author":"Yildiz","year":"2005","journal-title":"J Cardiovasc Pharmacol"},{"key":"10.1016\/j.juro.2008.03.188_bib9","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/S0015-0282(16)54796-7","article-title":"Deterioration of semen parameters over time in men with untreated varicocele: evidence of progressive testicular damage","volume":"57","author":"Chehval","year":"1992","journal-title":"Fertil Steril"},{"key":"10.1016\/j.juro.2008.03.188_bib10","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1016\/S0022-5347(01)66776-4","article-title":"The effect of varicocelectomy on serum testosterone levels in infertile men with varicoceles","volume":"154","author":"Su","year":"1995","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2008.03.188_bib11","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1046\/j.1464-410x.1999.00353.x","article-title":"The effect of microsurgical varicocelectomy on serum follicle stimulating hormone, testosterone and free testosterone levels in infertile men with varicocele","volume":"84","author":"Cayan","year":"1999","journal-title":"BJU Int"},{"key":"10.1016\/j.juro.2008.03.188_bib12","first-page":"200","article-title":"Andrological parameters in patients with varicocele and fertility disorders treated by high ligation of the left spermatic vein","volume":"31","author":"Segenreich","year":"1986","journal-title":"Int J Fertil"},{"key":"10.1016\/j.juro.2008.03.188_bib13","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.fertnstert.2004.06.047","article-title":"Semen quality and oxidative stress scores in fertile and infertile patients with varicocele","volume":"83","author":"Pasqualotto","year":"2007","journal-title":"Fertil Steril"},{"key":"10.1016\/j.juro.2008.03.188_bib14","doi-asserted-by":"crossref","first-page":"149","DOI":"10.3109\/01485018908986765","article-title":"Biochemical changes in testicular varicocele","volume":"22","author":"Fujisawa","year":"1989","journal-title":"Arch Androl"},{"key":"10.1016\/j.juro.2008.03.188_bib15","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1046\/j.1464-410X.2000.00853.x","article-title":"The role of adrenomedullin in varicocele and impotence","volume":"86","author":"Ozbek","year":"2000","journal-title":"BJU Int"},{"key":"10.1016\/j.juro.2008.03.188_bib16","doi-asserted-by":"crossref","first-page":"173","DOI":"10.3109\/01485018308987560","article-title":"FSH, LH, E2, progesterone, and testosterone in peripheral blood, spermatic vein, and semen of subfertile men with varicocele","volume":"10","author":"Ibrahim","year":"1983","journal-title":"Arch Androl"},{"issue":"suppl.","key":"10.1016\/j.juro.2008.03.188_bib17","first-page":"78","article-title":"Testosterone and testosterone precursors in the spermatic vein of young and old men","volume":"208","author":"Pirke","year":"1977","journal-title":"Acta Endocrinol"},{"key":"10.1016\/j.juro.2008.03.188_bib18","first-page":"353","article-title":"Concentrations de sept steroides dans la veine spermatique de l'homme","volume":"36","author":"Scholler","year":"1975","journal-title":"Ann Endocrinol (Paris)"},{"key":"10.1016\/j.juro.2008.03.188_bib19","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1046\/j.1464-410X.2000.00735.x","article-title":"The prevalence of varicocele and varicocele-related testicular atrophy in Turkish children and adolescents","volume":"86","author":"Akbay","year":"2000","journal-title":"BJU Int"},{"key":"10.1016\/j.juro.2008.03.188_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1055\/s-2007-949657","article-title":"Vasodilating mechanisms of testosterone","volume":"115","author":"Y\u0131ld\u0131z","year":"2007","journal-title":"Exp Clin Endocrinol Diabetes"}],"container-title":["Journal of Urology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0022534708009294?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0022534708009294?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.jurology.com\/doi\/pdf\/10.1016\/j.juro.2008.03.188","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T01:16:12Z","timestamp":1651194972000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jurology.com\/doi\/10.1016\/j.juro.2008.03.188"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,8]]}},"alternative-id":["10.1016\/j.juro.2008.03.188"],"URL":"https:\/\/doi.org\/10.1016\/j.juro.2008.03.188","relation":{},"ISSN":["0022-5347","1527-3792"],"issn-type":[{"value":"0022-5347","type":"print"},{"value":"1527-3792","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,8]]}}}