{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T05:39:17Z","timestamp":1740202757066,"version":"3.37.3"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Urology"],"published-print":{"date-parts":[[2010,8]]},"DOI":"10.1016\/j.juro.2010.03.104","type":"journal-article","created":{"date-parts":[[2010,6,21]],"date-time":"2010-06-21T00:47:06Z","timestamp":1277081226000},"page":"783-789","source":"Crossref","is-referenced-by-count":9,"title":["Spinal Effects of the Fesoterodine Metabolite 5-Hydroxymethyl Tolterodine and\/or Doxazosin in Rats With or Without Partial Urethral Obstruction"],"prefix":"10.1097","volume":"184","author":[{"given":"Claudius","family":"F\u00fcllhase","sequence":"first","affiliation":[{"name":"Wake Forest Institute for Regenerative Medicine, Wake Forest University, Winston-Salem, North Carolina"},{"name":"Department of Urology, University Hospital Grosshadern, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Soler","sequence":"additional","affiliation":[{"name":"Wake Forest Institute for Regenerative Medicine, Wake Forest University, Winston-Salem, North Carolina"},{"name":"Division of Urology, Federal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Gratzke","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital Grosshadern, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Brodsky","sequence":"additional","affiliation":[{"name":"Pfizer, Inc., New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George J.","family":"Christ","sequence":"additional","affiliation":[{"name":"Wake Forest Institute for Regenerative Medicine, Wake Forest University, Winston-Salem, North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl-Erik","family":"Andersson","sequence":"additional","affiliation":[{"name":"Wake Forest Institute for Regenerative Medicine, Wake Forest University, Winston-Salem, North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"10.1016\/j.juro.2010.03.104_bib1","doi-asserted-by":"crossref","first-page":"2319","DOI":"10.1001\/jama.296.19.2319","article-title":"Tolterodine and tamsulosin for treatment of men with lower urinary tract symptoms and overactive bladder: a randomized controlled trial","volume":"296","author":"Kaplan","year":"2006","journal-title":"JAMA"},{"key":"10.1016\/j.juro.2010.03.104_bib2","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1111\/j.1464-410X.2004.05039.x","article-title":"Comparison of doxazosin with or without tolterodine in men with symptomatic bladder outlet obstruction and an overactive bladder","volume":"94","author":"Lee","year":"2004","journal-title":"BJU Int"},{"key":"10.1016\/j.juro.2010.03.104_bib3","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1097\/00029330-200703010-00004","article-title":"Efficacy and safety of combined therapy with terazosin and tolterodine for patients with lower urinary tract symptoms associated with benign prostatic hyperplasia: a prospective study","volume":"120","author":"Yang","year":"2007","journal-title":"Chin Med J (Engl)"},{"key":"10.1016\/j.juro.2010.03.104_bib4","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/j.1742-1241.2007.01625.x","article-title":"Effects of oxybutynin transdermal system on health-related quality of life and safety in men with overactive bladder and prostate conditions","volume":"62","author":"Staskin","year":"2008","journal-title":"Int J Clin Pract"},{"key":"10.1016\/j.juro.2010.03.104_bib5","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1016\/j.eururo.2006.09.019","article-title":"Population-based survey of urinary incontinence, overactive bladder, and other lower urinary tract symptoms in five countries: results of the EPIC study","volume":"50","author":"Irwin","year":"2006","journal-title":"Eur Urol"},{"key":"10.1016\/j.juro.2010.03.104_bib6","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.eururo.2008.03.109","article-title":"Lower urinary tract symptoms revisited: a broader clinical perspective","volume":"54","author":"Chapple","year":"2008","journal-title":"Eur Urol"},{"key":"10.1016\/j.juro.2010.03.104_bib7","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1111\/j.1464-410X.2007.07205.x","article-title":"Muscarinic receptor antagonists for overactive bladder","volume":"100","author":"Abrams","year":"2007","journal-title":"BJU Int"},{"key":"10.1016\/j.juro.2010.03.104_bib8","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1038\/ncpuro0836","article-title":"Pharmacology of alpha1-adrenoceptor antagonists in the lower urinary tract and central nervous system","volume":"4","author":"Andersson","year":"2007","journal-title":"Nat Clin Pract Urol"},{"key":"10.1016\/j.juro.2010.03.104_bib9","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1002\/nau.20500","article-title":"LUTS treatment: future treatment options","volume":"26","author":"Andersson","year":"2007","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.juro.2010.03.104_bib10","doi-asserted-by":"crossref","first-page":"2595","DOI":"10.2165\/00003495-200363230-00003","article-title":"CNS involvement in overactive bladder: pathophysiology and opportunities for pharmacological intervention","volume":"63","author":"Andersson","year":"2003","journal-title":"Drugs"},{"key":"10.1016\/j.juro.2010.03.104_bib11","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1111\/j.1476-5381.1996.tb15288.x","article-title":"Micturition in conscious rats with and without bladder outlet obstruction: role of spinal alpha 1-adrenoceptors","volume":"117","author":"Ishizuka","year":"1996","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.juro.2010.03.104_bib12","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1111\/j.1464-410X.2007.07358.x","article-title":"Pharmacological characterization of a novel investigational antimuscarinic drug, fesoterodine, in vitro and in vivo","volume":"101","author":"Ney","year":"2008","journal-title":"BJU Int"},{"key":"10.1016\/j.juro.2010.03.104_bib13","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/j.urology.2005.06.070","article-title":"Evaluation of two techniques of partial urethral obstruction in the male rat model of bladder outlet obstruction","volume":"66","author":"Melman","year":"2005","journal-title":"Urology"},{"key":"10.1016\/j.juro.2010.03.104_bib14","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1016\/S0022-5347(17)44485-5","article-title":"Cystometrical evaluation of bladder instability in rats with infravesical outflow obstruction","volume":"137","author":"Malmgren","year":"1987","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2010.03.104_bib15","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1016\/0031-9384(76)90029-9","article-title":"Chronic catheterization of the spinal subarachnoid space","volume":"17","author":"Yaksh","year":"1976","journal-title":"Physiol Behav"},{"key":"10.1016\/j.juro.2010.03.104_bib16","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1002\/(SICI)1520-6777(1997)16:3<191::AID-NAU8>3.0.CO;2-9","article-title":"Effects of spinal alpha 1-adrenoceptor antagonism on bladder activity induced by apomorphine in conscious rats with and without bladder outlet obstruction","volume":"16","author":"Ishizuka","year":"1997","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.juro.2010.03.104_bib17","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1097\/01.ju.0000070926.39442.4c","article-title":"Bladder overactivity in mice after 1 week of outlet obstruction","volume":"170","author":"Schr\u00f6der","year":"2003","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2010.03.104_bib18","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1016\/S0022-5347(17)38477-X","article-title":"The guinea pig as a model of gradual urethral obstruction","volume":"145","author":"Mostwin","year":"1991","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2010.03.104_bib19","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/S0022-3565(24)29617-8","article-title":"Central muscarinic mechanisms regulating voiding in rats","volume":"297","author":"Ishiura","year":"2001","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.juro.2010.03.104_bib20","doi-asserted-by":"crossref","DOI":"10.1111\/j.1464-410X.2009.08515.x","article-title":"Effects of cholinesterase inhibition in supraspinal and spinal neural pathways on the micturition reflex in rats","author":"Masuda","year":"2009","journal-title":"BJU Int"},{"key":"10.1016\/j.juro.2010.03.104_bib21","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1007\/PL00005014","article-title":"Stimulation of bladder activity by volume, L-dopa and capsaicin in normal conscious rats\u2013effects of spinal alpha 1-adrenoceptor blockade","volume":"355","author":"Ishizuka","year":"1997","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"10.1016\/j.juro.2010.03.104_bib22","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/j.eururo.2007.01.016","article-title":"The influence of alpha1-adrenoreceptors on neuropeptide release from primary sensory neurons of the lower urinary tract","volume":"52","author":"Trevisani","year":"2007","journal-title":"Eur Urol"},{"key":"10.1016\/j.juro.2010.03.104_bib23","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1002\/nau.20253","article-title":"Improvement of bladder storage function by alpha1-blocker depends on the suppression of C-fiber afferent activity in rats","volume":"25","author":"Yokoyama","year":"2006","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.juro.2010.03.104_bib24","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/S0022-3565(25)22656-8","article-title":"Micturition in the unanesthetized rat: spinal vs. peripheral pharmacology of the adrenergic system","volume":"245","author":"Durant","year":"1988","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.juro.2010.03.104_bib25","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/S0022-5347(09)61950-9","article-title":"Effects of fesoterodine, a novel antimuscarinic, alone and in combination with an \u03b1-receptor blocker, doxazosin, on bladder function in obstructed rats","volume":"181","author":"Fullhase","year":"2009","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2010.03.104_bib26","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/S0022-5347(09)60241-X","article-title":"Assessment of central nervous system access of a new antimuscarinic drug, fesoterodine","volume":"181","author":"Kay","year":"2009","journal-title":"J Urol"}],"container-title":["Journal of Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022534710032027?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022534710032027?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.jurology.com\/doi\/pdf\/10.1016\/j.juro.2010.03.104","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T02:52:49Z","timestamp":1740192769000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jurology.com\/doi\/10.1016\/j.juro.2010.03.104"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,8]]}},"alternative-id":["10.1016\/j.juro.2010.03.104"],"URL":"https:\/\/doi.org\/10.1016\/j.juro.2010.03.104","relation":{},"ISSN":["0022-5347","1527-3792"],"issn-type":[{"type":"print","value":"0022-5347"},{"type":"electronic","value":"1527-3792"}],"subject":[],"published":{"date-parts":[[2010,8]]}}}