{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T15:27:35Z","timestamp":1760369255810},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Urology"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1016\/j.juro.2015.12.033","type":"journal-article","created":{"date-parts":[[2015,12,15]],"date-time":"2015-12-15T18:15:34Z","timestamp":1450203334000},"page":"544-545","source":"Crossref","is-referenced-by-count":2,"title":["Urothelial Layers: Not All Created Equal"],"prefix":"10.1097","volume":"195","author":[{"given":"Lori","family":"Birder","sequence":"first","affiliation":[{"name":"Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"10.1016\/j.juro.2015.12.033_bib1","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.juro.2015.10.066","article-title":"Evidence of nonuniformity in urothelium barrier function between the upper urinary tract and bladder","volume":"195","author":"Williams","year":"2016","journal-title":"J Urol"},{"key":"10.1016\/j.juro.2015.12.033_bib2","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1208\/s12248-010-9219-8","article-title":"Bladder tissue pharmacokinetics of intravesical mitomycin C and suramin in dogs","volume":"12","author":"Hu","year":"2010","journal-title":"AAPS J"},{"key":"10.1016\/j.juro.2015.12.033_bib3","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1083\/jcb.200505035","article-title":"Cellular basis of urothelial squamous metaplasia: roles of lineage heterogeneity and cell replacement","volume":"171","author":"Liang","year":"2005","journal-title":"J\u00a0Cell Biol"},{"key":"10.1016\/j.juro.2015.12.033_bib4","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1152\/physrev.00030.2012","article-title":"Urothelial signaling","volume":"93","author":"Birder","year":"2013","journal-title":"Physiol Rev"},{"key":"10.1016\/j.juro.2015.12.033_bib5","doi-asserted-by":"crossref","first-page":"F1477","DOI":"10.1152\/ajprenal.00327.2009","article-title":"Cell biology and physiology of the uroepithelium","volume":"297","author":"Khandelwal","year":"2009","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1016\/j.juro.2015.12.033_bib6","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1038\/ki.2009.73","article-title":"Uroplakins in urothelial biology, function and disease","volume":"75","author":"Wu","year":"2009","journal-title":"Kidney Int"},{"key":"10.1016\/j.juro.2015.12.033_bib7","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1046\/j.1523-1755.2000.00251.x","article-title":"Cellular and molecular aspects of drug transport in the kidney","volume":"58","author":"Inui","year":"2000","journal-title":"Kidney Int"},{"key":"10.1016\/j.juro.2015.12.033_bib8","doi-asserted-by":"crossref","first-page":"e022755","DOI":"10.1371\/journal.pone.0122766","article-title":"Bladder uptake of liposomes after intravesical administration occurs by endocytosis","volume":"10","author":"Rajaganapathy","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.juro.2015.12.033_bib9","doi-asserted-by":"crossref","first-page":"473823","DOI":"10.1155\/2014\/473823","article-title":"Preparation and characterization of gelatin-based mucoadhesive nanocomposites as intravesical gene delivery scaffolds","volume":"2014","author":"Liu","year":"2014","journal-title":"BioMed Res Int"},{"key":"10.1016\/j.juro.2015.12.033_bib10","first-page":"3181","article-title":"State of the art in intravesical therapy for lower urinary tract symptoms","volume":"12","author":"Tyagi","year":"2010","journal-title":"Rev Urol"},{"key":"10.1016\/j.juro.2015.12.033_bib11","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s40846-015-0060-5","article-title":"Application of nanoparticles in urothelial cancer of the urinary bladder","volume":"35","author":"Chen","year":"2015","journal-title":"J Med Biol Eng"}],"container-title":["Journal of Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022534715054063?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022534715054063?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.jurology.com\/doi\/pdf\/10.1016\/j.juro.2015.12.033","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T04:02:16Z","timestamp":1651204936000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jurology.com\/doi\/10.1016\/j.juro.2015.12.033"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["10.1016\/j.juro.2015.12.033"],"URL":"https:\/\/doi.org\/10.1016\/j.juro.2015.12.033","relation":{},"ISSN":["0022-5347","1527-3792"],"issn-type":[{"value":"0022-5347","type":"print"},{"value":"1527-3792","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3]]}}}