{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T04:25:15Z","timestamp":1793161515058,"version":"4.5.0"},"reference-count":51,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,8,4]],"date-time":"2021-08-04T00:00:00Z","timestamp":1628035200000},"content-version":"vor","delay-in-days":34,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","valueinhealthjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Value in Health"],"published-print":{"date-parts":[[2021,7]]},"DOI":"10.1016\/j.jval.2021.01.008","type":"journal-article","created":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T22:06:48Z","timestamp":1617314808000},"page":"939-947","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"title":["Cost-Effectiveness of Propofol (Diprivan) Versus Inhalational Anesthetics to Maintain General Anesthesia in Noncardiac Surgery in the United States"],"prefix":"10.1016","volume":"24","author":[{"given":"Tim","family":"Kampmeier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Rehberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdul Jabbar","family":"Omar Alsaleh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Schraag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny","family":"Pham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Westphal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jval.2021.01.008_bib1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S2214-109X(15)70087-2","article-title":"Estimated need for surgery worldwide based on prevalence of diseases: a modelling strategy for the WHO Global Health Estimate","volume":"3","author":"Rose","year":"2015","journal-title":"Lancet Glob Health"},{"issue":"Suppl 1","key":"10.1016\/j.jval.2021.01.008_bib3","first-page":"e90","article-title":"Influence of propofol-based total intravenous anaesthesia on peri-operative outcome measures: a narrative review","volume":"75","author":"Irwin","year":"2020","journal-title":"Anaesthesia"},{"issue":"4","key":"10.1016\/j.jval.2021.01.008_bib4","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1213\/ANE.0000000000001504","article-title":"Does propofol anesthesia lead to less postoperative pain compared with inhalational anesthesia? a systematic review and meta-analysis","volume":"123","author":"Peng","year":"2016","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jval.2021.01.008_bib5","article-title":"Intravenous versus inhalational maintenance of anaesthesia for postoperative cognitive outcomes in elderly people undergoing non-cardiac surgery","volume":"8","author":"Miller","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jval.2021.01.008_bib6","article-title":"Effects of sevoflurane versus other general anaesthesia on emergence agitation in children","volume":"9","author":"Costi","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"issue":"1","key":"10.1016\/j.jval.2021.01.008_bib7","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1186\/s12871-018-0632-3","article-title":"Propofol vs. inhalational agents to maintain general anaesthesia in ambulatory and in-patient surgery: a systematic review and meta-analysis","volume":"18","author":"Schraag","year":"2018","journal-title":"BMC Anesthesiol"},{"issue":"10","key":"10.1016\/j.jval.2021.01.008_bib8","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1001\/jama.287.10.1233","article-title":"Postoperative nausea and vomiting\u2014can it be eliminated?","volume":"287","author":"Gan","year":"2002","journal-title":"JAMA"},{"issue":"5","key":"10.1016\/j.jval.2021.01.008_bib9","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1093\/bja\/aes276","article-title":"Evidence-based analysis of risk factors for postoperative nausea and vomiting","volume":"109","author":"Apfel","year":"2012","journal-title":"Br J Anaesth"},{"issue":"3","key":"10.1016\/j.jval.2021.01.008_bib10","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/aas.12651","article-title":"Enhanced Recovery After Surgery (ERAS) for gastrointestinal surgery, part 2: consensus statement for anaesthesia practice","volume":"60","author":"Feldheiser","year":"2016","journal-title":"Acta Anaesthesiol Scand"},{"issue":"8","key":"10.1016\/j.jval.2021.01.008_bib11","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1111\/j.1365-2044.1990.tb14399.x","article-title":"A\u00a0postoperative analysis of the patient\u2019s view of anaesthesia in a Netherlands teaching hospital","volume":"45","author":"van Wijk","year":"1990","journal-title":"Anaesthesia"},{"issue":"2","key":"10.1016\/j.jval.2021.01.008_bib12","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1213\/00000539-200102000-00022","article-title":"How much are patients willing to pay to avoid postoperative nausea and vomiting?","volume":"92","author":"Gan","year":"2001","journal-title":"Anesth Analg"},{"issue":"1","key":"10.1016\/j.jval.2021.01.008_bib13","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1093\/oxfordjournals.bja.a013366","article-title":"Validity and reliability of a postoperative quality of recovery score: the QoR-40","volume":"84","author":"Myles","year":"2000","journal-title":"Br J Anaesth"},{"issue":"3","key":"10.1016\/j.jval.2021.01.008_bib14","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1097\/EJA.0b013e328357e584","article-title":"Predictors of patient satisfaction with anaesthesia and surgery care: a cohort study using the Postoperative Quality of Recovery Scale","volume":"30","author":"Royse","year":"2013","journal-title":"Eur J Anaesthesiol"},{"issue":"5","key":"10.1016\/j.jval.2021.01.008_bib15","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1592\/phco.21.6.540.34543","article-title":"Impact of antiemetic selection on postoperative nausea and vomiting and patient satisfaction","volume":"21","author":"Darkow","year":"2001","journal-title":"Pharmacotherapy"},{"issue":"6","key":"10.1016\/j.jval.2021.01.008_bib16","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1185\/030079906X104830","article-title":"Postoperative nausea and vomiting following inpatient surgeries in a teaching hospital: a retrospective database analysis","volume":"22","author":"Habib","year":"2006","journal-title":"Curr Med Res Opin"},{"issue":"5","key":"10.1016\/j.jval.2021.01.008_bib17","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1213\/ANE.0000000000003334","article-title":"Cost-effectiveness research in anesthesiology","volume":"127","author":"Teja","year":"2018","journal-title":"Anesth Analg"},{"issue":"23","key":"10.1016\/j.jval.2021.01.008_bib18","doi-asserted-by":"crossref","first-page":"323","DOI":"10.2165\/00019053-200523040-00003","article-title":"Pharmacoeconomic analyses using discrete event simulation","volume":"4","author":"Caro","year":"2005","journal-title":"Pharmacoeconomics"},{"issue":"3","key":"10.1016\/j.jval.2021.01.008_bib19","doi-asserted-by":"crossref","first-page":"319","DOI":"10.4103\/0259-1162.143122","article-title":"Comparison of vital capacity induction with sevoflurane to intravenous induction with propofol in adult patients","volume":"8","author":"Dongare","year":"2014","journal-title":"Anesth Essays Res"},{"issue":"2","key":"10.1016\/j.jval.2021.01.008_bib20","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1034\/j.1399-6576.2003.00041.x","article-title":"Different benefit of bispectal index (BIS) in desflurane and propofol anesthesia","volume":"47","author":"Luginb\u00fchl","year":"2003","journal-title":"Acta Anaesthesiol Scand"},{"issue":"4","key":"10.1016\/j.jval.2021.01.008_bib21","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1213\/ANE.0000000000001124","article-title":"Economic and environmental considerations during low fresh gas flow volatile agent administration after change to a nonreactive carbon dioxide absorbent","volume":"122","author":"Epstein","year":"2016","journal-title":"Anesth Analg"},{"issue":"11","key":"10.1016\/j.jval.2021.01.008_bib22","doi-asserted-by":"crossref","first-page":"743","DOI":"10.3390\/medicina46110105","article-title":"The effects of sevoflurane and propofol on cerebral hemodynamics during intracranial tumors surgery under monitoring the depth of anesthesia","volume":"46","author":"Banevi\u010dius","year":"2010","journal-title":"Medicina (Kaunas)"},{"issue":"4","key":"10.1016\/j.jval.2021.01.008_bib23","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1213\/01.ANE.0000130616.57678.80","article-title":"Tactile assessment for the reversibility of rocuronium-induced neuromuscular blockade during propofol or sevoflurane anesthesia","volume":"99","author":"Kim","year":"2004","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jval.2021.01.008_bib24","author":"Higgins"},{"issue":"1","key":"10.1016\/j.jval.2021.01.008_bib27","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1186\/s12871-018-0563-z","article-title":"Cost-effectiveness of anesthesia maintained with sevoflurane or propofol with and without additional monitoring: a prospective, randomized controlled trial","volume":"18","author":"Bocskai","year":"2018","journal-title":"BMC Anesthesiol"},{"issue":"2","key":"10.1016\/j.jval.2021.01.008_bib28","first-page":"115","article-title":"Cost-effectiveness and high patient satisfaction in the elderly: sevoflurane versus propofol anaesthesia","volume":"21","author":"Luntz","year":"2004","journal-title":"Eur J Anaesthesiol"},{"issue":"2","key":"10.1016\/j.jval.2021.01.008_bib29","doi-asserted-by":"crossref","first-page":"155","DOI":"10.4103\/0259-1162.156290","article-title":"Comparative evaluation of cost effectiveness and recovery profile between propofol and sevoflurane in laparoscopic cholecystectomy","volume":"9","author":"Singh","year":"2015","journal-title":"Anesth Essays Res"},{"issue":"3","key":"10.1016\/j.jval.2021.01.008_bib30","first-page":"207","article-title":"Use of a remifentanil and propofol combination in outpatients to facilitate rapid discharge home","volume":"73","author":"Brady","year":"2005","journal-title":"AANA J"},{"issue":"5","key":"10.1016\/j.jval.2021.01.008_bib31","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1046\/j.1365-2044.2003.03125.x","article-title":"Clinical and economic choices in anaesthesia for day surgery: a prospective randomised controlled trial","volume":"58","author":"Elliott","year":"2003","journal-title":"Anaesthesia"},{"key":"10.1016\/j.jval.2021.01.008_bib32","unstructured":"Fresenius Kabi. Internal analysis of propofol prices using IQVIA (IMS) 2006-2019 US data. Updated\u00a02020."},{"issue":"3","key":"10.1016\/j.jval.2021.01.008_bib33","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1097\/ALN.0b013e3182655eb2","article-title":"Cost-effectiveness analysis of goal-directed hemodynamic treatment of elderly hip fracture patients: before clinical research starts","volume":"117","author":"Bartha","year":"2012","journal-title":"Anesthesiology"},{"issue":"5","key":"10.1016\/j.jval.2021.01.008_bib34","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1097\/CCM.0000000000000164","article-title":"A\u00a0cost-effectiveness analysis of postoperative goal-directed therapy for high-risk surgical patients","volume":"42","author":"Ebm","year":"2014","journal-title":"Crit Care Med"},{"issue":"6","key":"10.1016\/j.jval.2021.01.008_bib35","doi-asserted-by":"crossref","first-page":"R296","DOI":"10.1186\/cc10592","article-title":"A\u00a0pragmatic multi-centre randomised controlled trial of fluid loading in high-risk surgical patients undergoing major elective surgery: the FOCCUS study","volume":"15","author":"Cuthbertson","year":"2011","journal-title":"Crit Care"},{"issue":"2","key":"10.1016\/j.jval.2021.01.008_bib36","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s00590-013-1170-9","article-title":"The cost-effectiveness of multi-component interventions to prevent delirium in older people undergoing surgical repair of hip fracture","volume":"24","author":"Akunne","year":"2014","journal-title":"Eur J Orthop Surg Traumatol"},{"issue":"4","key":"10.1016\/j.jval.2021.01.008_bib37","doi-asserted-by":"crossref","first-page":"326.e1","DOI":"10.1016\/j.ajog.2011.05.043","article-title":"Cost-effectiveness of general anesthesia vs spinal anesthesia in fast-track abdominal benign hysterectomy","volume":"205","author":"Borendal Wodlin","year":"2011","journal-title":"Am J Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.jval.2021.01.008_bib38","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1086\/663704","article-title":"Cost-effectiveness of preoperative nasal mupirocin treatment in preventing surgical site infection in patients undergoing total hip and knee arthroplasty: a cost-effectiveness analysis","volume":"33","author":"Courville","year":"2012","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"11","key":"10.1016\/j.jval.2021.01.008_bib39","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1086\/656591","article-title":"The economic effect of screening orthopedic surgery patients preoperatively for methicillin-resistant Staphylococcus aureus","volume":"31","author":"Lee","year":"2010","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"8","key":"10.1016\/j.jval.2021.01.008_bib40","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1001\/jamasurg.2019.0995","article-title":"Association between use of enhanced recovery after surgery protocol and postoperative complications in colorectal surgery: the Postoperative Outcomes Within Enhanced Recovery After Surgery Protocol (POWER) Study","volume":"154","author":"Ripoll\u00e9s-Melchor","year":"2019","journal-title":"JAMA Surg"},{"issue":"3","key":"10.1016\/j.jval.2021.01.008_bib41","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1001\/jamasurg.2016.4952","article-title":"Enhanced recovery after surgery: a review","volume":"152","author":"Ljungqvist","year":"2017","journal-title":"JAMA Surg"},{"key":"10.1016\/j.jval.2021.01.008_bib42","doi-asserted-by":"crossref","DOI":"10.1213\/ANE.0000000000004833","article-title":"Fourth consensus guidelines for the management of postoperative nausea and vomiting","author":"Gan","year":"2020","journal-title":"Anesth Analg"},{"issue":"5","key":"10.1016\/j.jval.2021.01.008_bib43","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1093\/bja\/88.5.659","article-title":"Volatile anaesthetics may be the main cause of early but not delayed postoperative vomiting: a randomized controlled trial of factorial design","volume":"88","author":"Apfel","year":"2002","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.jval.2021.01.008_bib44","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.clnesp.2019.08.010","article-title":"Nausea and vomiting in a colorectal ERAS program: impact on nutritional recovery and the length of hospital stay","volume":"34","author":"McLoughlin","year":"2019","journal-title":"Clin Nutr ESPEN"},{"key":"10.1016\/j.jval.2021.01.008_bib45","doi-asserted-by":"crossref","first-page":"353","DOI":"10.2147\/PROM.S156279","article-title":"The importance of patient-reported outcomes in clinical trials and strategies for future optimization","volume":"9","author":"Mercieca-Bebber","year":"2018","journal-title":"Patient Relat Outcome Meas"},{"issue":"40","key":"10.1016\/j.jval.2021.01.008_bib46","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000012699","article-title":"Patient quality of recovery on the day of surgery after propofol total intravenous anesthesia for vitrectomy: a randomized controlled trial","volume":"97","author":"Na","year":"2018","journal-title":"Medicine"},{"issue":"4","key":"10.1016\/j.jval.2021.01.008_bib47","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1093\/bja\/aeu405","article-title":"Type of anaesthesia and patient quality of recovery: a randomized trial comparing propofol-remifentanil total i.v. anaesthesia with desflurane anaesthesia","volume":"114","author":"Lee","year":"2015","journal-title":"Br J Anaesth"},{"issue":"2","key":"10.1016\/j.jval.2021.01.008_bib48","doi-asserted-by":"crossref","first-page":"308","DOI":"10.2478\/v10039-010-0033-4","article-title":"Propofol vs isoflurane anesthesia-incidence of PONV in patients at maxillofacial surgery","volume":"55","author":"Gecaj-Gashi","year":"2010","journal-title":"Adv Med Sci"},{"issue":"1","key":"10.1016\/j.jval.2021.01.008_bib49","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1097\/00000542-199907000-00034","article-title":"Recovery profile, costs, and patient satisfaction with propofol and sevoflurane for fast-track office-based anesthesia","volume":"91","author":"Tang","year":"1999","journal-title":"Anesthesiology"},{"issue":"5","key":"10.1016\/j.jval.2021.01.008_bib50","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1093\/bja\/aeg243","article-title":"Patient well-being after general anaesthesia: a prospective, randomized, controlled multi-centre trial comparing intravenous and inhalation anaesthesia","volume":"91","author":"Hofer","year":"2003","journal-title":"Br J Anaesth"},{"issue":"5","key":"10.1016\/j.jval.2021.01.008_bib51","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1111\/pan.12359","article-title":"Cost-effectiveness of intravenous acetaminophen for pediatric tonsillectomy","volume":"24","author":"Subramanyam","year":"2014","journal-title":"Paediatr Anaesth"},{"issue":"11","key":"10.1016\/j.jval.2021.01.008_bib52","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1046\/j.1365-2044.2000.01547.x","article-title":"Costing anaesthetic practice","volume":"55","author":"Kendell","year":"2000","journal-title":"Anaesthesia"},{"issue":"6","key":"10.1016\/j.jval.2021.01.008_bib53","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1080\/22201173.2012.10872871","article-title":"Calculation of comparative utilisation and cost: a South African perspective on intravenous vs. inhalational anaesthesia for procedures of differing duration","volume":"18","author":"Ryksen","year":"2014","journal-title":"South Afr J Anaesth Analg"},{"issue":"11","key":"10.1016\/j.jval.2021.01.008_bib54","first-page":"21266","article-title":"Cost of general anesthesia during radical gastrectomy using different specifications of propofol: cost-minimization analyses","volume":"8","author":"Hu","year":"2015","journal-title":"Int J Clin Exp Med"}],"container-title":["Value in Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S109830152100111X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S109830152100111X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T01:23:20Z","timestamp":1761096200000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S109830152100111X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":51,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["S109830152100111X"],"URL":"https:\/\/doi.org\/10.1016\/j.jval.2021.01.008","relation":{},"ISSN":["1098-3015"],"issn-type":[{"value":"1098-3015","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cost-Effectiveness of Propofol (Diprivan) Versus Inhalational Anesthetics to Maintain General Anesthesia in Noncardiac Surgery in the United States","name":"articletitle","label":"Article Title"},{"value":"Value in Health","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jval.2021.01.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 ISPOR-The Professional Society for Health Economics and Outcomes Research. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}