{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T04:41:58Z","timestamp":1786941718885,"version":"build-2736575974"},"reference-count":49,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T00:00:00Z","timestamp":1771804800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006520","name":"Edwards Lifesciences Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006520","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","valueinhealthjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Value in Health"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.jval.2026.02.005","type":"journal-article","created":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T16:19:49Z","timestamp":1772036389000},"page":"1171-1179","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Cost-Effectiveness of TAVR Compared With Clinical Surveillance in Patients with Asymptomatic Severe Aortic Stenosis in the United States"],"prefix":"10.1016","volume":"29","author":[{"given":"Philippe","family":"G\u00e9n\u00e9reux","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew R.","family":"Reynolds","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcella A.","family":"Kelley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christin","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne J.","family":"Baron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9667","key":"10.1016\/j.jval.2026.02.005_bib1","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1016\/S0140-6736(09)60211-7","article-title":"Aortic stenosis","volume":"373","author":"Carabello","year":"2009","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.jval.2026.02.005_bib2","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0281811","article-title":"Racial and ethnic disparities in diagnosis, management and outcomes of aortic stenosis in the Medicare population","volume":"18","author":"Ahmed","year":"2023","journal-title":"PLOS One"},{"issue":"8","key":"10.1016\/j.jval.2026.02.005_bib3","doi-asserted-by":"crossref","first-page":"e41","DOI":"10.1161\/CIR.0000000000001303","article-title":"2025 heart disease and stroke statistics: a report of US and global data from the American Heart Association","volume":"151","author":"Martin","year":"2025","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.jval.2026.02.005_bib4","first-page":"e72","article-title":"ACC\/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association joint committee on clinical practice guidelines","volume":"143","author":"Otto","year":"2021","journal-title":"Circulation"},{"issue":"25","key":"10.1016\/j.jval.2026.02.005_bib5","doi-asserted-by":"crossref","first-page":"2683","DOI":"10.1016\/j.jacc.2012.09.018","article-title":"Cost-effectiveness of transcatheter aortic valve replacement compared with surgical aortic valve replacement in high-risk patients with severe aortic stenosis: results of the PARTNER (Placement of Aortic transcatheter Valves) trial (Cohort A)","volume":"60","author":"Reynolds","year":"2012","journal-title":"J Am Coll Cardiol"},{"issue":"7","key":"10.1016\/j.jval.2026.02.005_bib6","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1161\/CIRCULATIONAHA.118.035236","article-title":"Cost-effectiveness of transcatheter versus surgical aortic valve replacement in patients with severe aortic stenosis at intermediate risk","volume":"139","author":"Baron","year":"2019","journal-title":"Circulation"},{"issue":"21","key":"10.1016\/j.jval.2026.02.005_bib7","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1161\/CIRCULATIONAHA.122.062481","article-title":"Economic outcomes of transcatheter versus surgical aortic valve replacement in patients with severe aortic stenosis and low surgical risk: results from the PARTNER 3 trial","volume":"147","author":"Galper","year":"2023","journal-title":"Circulation"},{"issue":"3","key":"10.1016\/j.jval.2026.02.005_bib8","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.121.011295","article-title":"Contemporary costs associated with transcatheter versus surgical aortic valve replacement in Medicare beneficiaries","volume":"15","author":"Baron","year":"2022","journal-title":"Circ Cardiovasc Interv"},{"issue":"6","key":"10.1016\/j.jval.2026.02.005_bib9","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCOUTCOMES.116.003287","article-title":"Quantifying the shift toward transcatheter aortic valve replacement in low-risk patients: a meta-analysis","volume":"10","author":"De Sciscio","year":"2017","journal-title":"Circ Cardiovasc Qual Outcomes"},{"issue":"4","key":"10.1016\/j.jval.2026.02.005_bib10","doi-asserted-by":"crossref","first-page":"e25","DOI":"10.1016\/j.jacc.2020.11.018","article-title":"ACC\/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association joint committee on clinical practice guidelines","volume":"77","author":"Otto","year":"2021","journal-title":"J Am Coll Cardiol"},{"issue":"14","key":"10.1016\/j.jval.2026.02.005_bib11","doi-asserted-by":"crossref","first-page":"e1126","DOI":"10.4244\/EIJ-E-21-00009","article-title":"ESC\/EACTS Guidelines for the management of valvular heart disease","volume":"17","author":"Vahanian","year":"2022","journal-title":"EuroIntervention"},{"issue":"8","key":"10.1016\/j.jval.2026.02.005_bib12","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.jacc.2023.05.061","article-title":"ACC\/AHA and ESC\/EACTS guidelines for the management of valvular heart diseases: JACC guideline comparison","volume":"82","author":"Coisne","year":"2023","journal-title":"J Am Coll Cardiol"},{"issue":"3","key":"10.1016\/j.jval.2026.02.005_bib13","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1056\/NEJMoa2405880","article-title":"Transcatheter aortic-valve replacement for asymptomatic severe aortic stenosis","volume":"392","author":"G\u00e9n\u00e9reux","year":"2025","journal-title":"N Engl J Med"},{"issue":"9","key":"10.1016\/j.jval.2026.02.005_bib14","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1016\/j.jacc.2024.11.006","article-title":"Aortic valve replacement vs clinical surveillance in asymptomatic severe aortic stenosis: a systematic review and meta-analysis","volume":"85","author":"G\u00e9n\u00e9reux","year":"2025","journal-title":"J Am Coll Cardiol"},{"issue":"16","key":"10.1016\/j.jval.2026.02.005_bib15","article-title":"Early aortic valve replacement in asymptomatic severe aortic stenosis: a meta-analysis of randomized controlled trials","volume":"14","author":"Brar","year":"2025","journal-title":"Am J Cardiol"},{"issue":"2","key":"10.1016\/j.jval.2026.02.005_bib16","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1056\/NEJMoa1912846","article-title":"Early surgery or conservative care for asymptomatic aortic stenosis","volume":"382","author":"Kang","year":"2020","journal-title":"N Engl J Med"},{"issue":"9","key":"10.1016\/j.jval.2026.02.005_bib17","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1161\/CIRCULATIONAHA.121.057639","article-title":"Aortic valve replacement versus conservative treatment in asymptomatic severe aortic stenosis: the AVATAR trial","volume":"145","author":"Banovic","year":"2022","journal-title":"Circulation"},{"issue":"3","key":"10.1016\/j.jval.2026.02.005_bib18","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1001\/jama.2024.22730","article-title":"Early intervention in patients with asymptomatic severe aortic stenosis and myocardial fibrosis: the EVOLVED randomized clinical trial","volume":"333","author":"Loganath","year":"2025","journal-title":"JAMA"},{"key":"10.1016\/j.jval.2026.02.005_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijcard.2025.133269","article-title":"Early aortic valve replacement versus conservative management in asymptomatic severe aortic stenosis: meta-analysis of time-to-event data of randomized controlled trials","volume":"432","author":"Jacquemyn","year":"2025","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.jval.2026.02.005_bib20","series-title":"Medical Care in U.S. City Average, All Urban Consumers, not Seasonally Adjusted. Consumer Price Index for All Urban Consumers (CPI-U)","year":"2023"},{"issue":"21","key":"10.1016\/j.jval.2026.02.005_bib22","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.1056\/NEJMoa2307447","article-title":"Transcatheter aortic-valve replacement in low-risk patients at five years","volume":"389","author":"Mack","year":"2023","journal-title":"N Engl J Med"},{"issue":"3","key":"10.1016\/j.jval.2026.02.005_bib23","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.athoracsur.2014.09.030","article-title":"Very long-term outcomes of the Carpentier-Edwards Perimount valve in aortic position","volume":"99","author":"Bourguignon","year":"2015","journal-title":"Ann Thorac Surg"},{"issue":"4","key":"10.1016\/j.jval.2026.02.005_bib24","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.jcin.2018.11.008","article-title":"Impact of short-term complications on mortality and quality of life after transcatheter aortic valve replacement","volume":"12","author":"Arnold","year":"2019","journal-title":"JACC Cardiovasc Interv"},{"issue":"6","key":"10.1016\/j.jval.2026.02.005_bib25","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.jcin.2024.11.015","article-title":"1-year real-world outcomes of TAVR with the fifth-generation balloon-expandable valve in the United States","volume":"18","author":"Kini","year":"2025","journal-title":"JACC Cardiovasc Interv"},{"issue":"3","key":"10.1016\/j.jval.2026.02.005_bib26","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1007\/s11136-020-02650-y","article-title":"US population norms for the EQ-5D-5L and comparison of norms from face-to-face and online samples","volume":"30","author":"Jiang","year":"2021","journal-title":"Qual Life Res"},{"issue":"3","key":"10.1016\/j.jval.2026.02.005_bib27","doi-asserted-by":"crossref","first-page":"191","DOI":"10.2165\/00019053-200321030-00004","article-title":"A meta-analysis of quality-of-life estimates for stroke","volume":"21","author":"Tengs","year":"2003","journal-title":"Pharmacoeconomics"},{"key":"10.1016\/j.jval.2026.02.005_bib28","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.xjon.2022.08.002","article-title":"Ten-year outcomes of surgical aortic valve replacement with a contemporary supra-annular porcine valve in a Medicare population","volume":"12","author":"Wiechmann","year":"2022","journal-title":"JTCVS Open"},{"key":"10.1016\/j.jval.2026.02.005_bib29","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.xjon.2023.07.026","article-title":"Impact of reintervention after index aortic valve replacement on the risk of subsequent mortality","volume":"16","author":"Shi","year":"2023","journal-title":"JTCVS Open"},{"key":"10.1016\/j.jval.2026.02.005_bib30","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.ahj.2023.10.002","article-title":"Long-term risk of reintervention after transcatheter aortic valve replacement","volume":"267","author":"Baron","year":"2024","journal-title":"Am Heart J"},{"key":"10.1016\/j.jval.2026.02.005_bib32","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.ahj.2025.07.001","article-title":"Incremental cost of complications after TAVR and SAVR in contemporary clinical practice","volume":"290","author":"Harvey","year":"2025","journal-title":"Am Heart J"},{"key":"10.1016\/j.jval.2026.02.005_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev-med-043015-123540","article-title":"Cardiac pacing and defibrillation devices: cost and effectiveness","volume":"68","author":"Groeneveld","year":"2017","journal-title":"Annu Rev Med"},{"issue":"10","key":"10.1016\/j.jval.2026.02.005_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.jstrokecerebrovasdis.2023.107333","article-title":"Healthcare expenditure trends among adult stroke patients in the United States, 2011-2020","volume":"32","author":"Ramamoorthy","year":"2023","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"10.1016\/j.jval.2026.02.005_bib35","series-title":"Medicare Standard Analytic Files 100% Fee for Service Database","year":"2019"},{"issue":"6","key":"10.1016\/j.jval.2026.02.005_bib37","article-title":"The cost of waiting for a transcatheter aortic valve replacement in Medicare beneficiaries with severe aortic stenosis","volume":"8","author":"Sethi","year":"2024","journal-title":"Struct Heart"},{"issue":"19","key":"10.1016\/j.jval.2026.02.005_bib38","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.125.043486","article-title":"Acute valve syndrome before aortic valve replacement: impact on clinical outcomes, health care costs, and resource use","volume":"14","author":"G\u00e9n\u00e9reux","year":"2025","journal-title":"J Am Heart Assoc"},{"issue":"5","key":"10.1016\/j.jval.2026.02.005_bib39","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.124.014945","article-title":"Health care cost and resource utilization after aortic valve replacement according to the extent of cardiac damage","volume":"18","author":"G\u00e9n\u00e9reux","year":"2025","journal-title":"Circ Cardiovasc Interv"},{"issue":"4","key":"10.1016\/j.jval.2026.02.005_bib40","article-title":"Acute valve syndrome in aortic stenosis","volume":"9","author":"G\u00e9n\u00e9reux","year":"2024","journal-title":"Struct Heart"},{"issue":"23","key":"10.1016\/j.jval.2026.02.005_bib41","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1161\/CIRCULATIONAHA.125.074251","article-title":"New classification to describe clinical presentation in aortic stenosis: stable, progressive, and acute valve syndrome","volume":"151","author":"G\u00e9n\u00e9reux","year":"2025","journal-title":"Circulation"},{"issue":"10","key":"10.1016\/j.jval.2026.02.005_bib21","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1001\/jama.2016.12195","article-title":"Recommendations for conduct, methodological practices, and reporting of cost-effectiveness analyses: second panel on cost-effectiveness in health and medicine","volume":"316","author":"Sanders","year":"2016","journal-title":"JAMA"},{"issue":"9","key":"10.1016\/j.jval.2026.02.005_bib42","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1056\/NEJMp1405158","article-title":"Updating cost-effectiveness--the curious resilience of the $50,000-per-QALY threshold","volume":"371","author":"Neumann","year":"2014","journal-title":"N Engl J Med"},{"issue":"7","key":"10.1016\/j.jval.2026.02.005_bib44","article-title":"Aortic valve replacement in asymptomatic severe aortic stenosis: a systematic review and meta-analysis of observational studies and randomized trials","volume":"4","author":"G\u00e9n\u00e9reux","year":"2025","journal-title":"J Soc CardioVasc Angiogr Interv"},{"issue":"9","key":"10.1016\/j.jval.2026.02.005_bib45","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1161\/CIRCULATIONAHA.111.054072","article-title":"Cost-effectiveness of transcatheter aortic valve replacement compared with standard care among inoperable patients with severe aortic stenosis: results from the placement of aortic transcatheter valves (PARTNER) trial (Cohort B)","volume":"125","author":"Reynolds","year":"2012","journal-title":"Circulation"},{"issue":"9","key":"10.1016\/j.jval.2026.02.005_bib46","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1016\/j.jacc.2021.11.060","article-title":"Trends in utilization of aortic valve replacement for severe aortic stenosis","volume":"79","author":"Li","year":"2022","journal-title":"J Am Coll Cardiol"},{"issue":"45","key":"10.1016\/j.jval.2026.02.005_bib47","doi-asserted-by":"crossref","first-page":"3351","DOI":"10.1093\/eurheartj\/ehx381","article-title":"Staging classification of aortic stenosis based on the extent of cardiac damage","volume":"38","author":"G\u00e9n\u00e9reux","year":"2017","journal-title":"Eur Heart J"},{"issue":"5","key":"10.1016\/j.jval.2026.02.005_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.jacadv.2024.100959","article-title":"Cardiac damage staging predicts outcomes in aortic valve stenosis after aortic valve replacement: meta-analysis","volume":"3","author":"Abdelfattah","year":"2024","journal-title":"JACC Adv"},{"issue":"8","key":"10.1016\/j.jval.2026.02.005_bib49","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.jacc.2022.05.006","article-title":"Evolution and prognostic impact of cardiac damage after aortic valve replacement","volume":"80","author":"G\u00e9n\u00e9reux","year":"2022","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"10.1016\/j.jval.2026.02.005_bib50","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1186\/s12955-020-01508-8","article-title":"Impact of hospitalisation on health-related quality of life in patients with chronic heart failure","volume":"18","author":"Albuquerque de Almeida","year":"2020","journal-title":"Health Qual Life Outcomes"},{"issue":"19","key":"10.1016\/j.jval.2026.02.005_bib51","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.123.030766","article-title":"Impact of new cardiovascular events on quality of life and hospital costs in people with cardiovascular disease in the United Kingdom and United States","volume":"12","author":"Lui","year":"2023","journal-title":"J Am Heart Assoc"},{"issue":"6","key":"10.1016\/j.jval.2026.02.005_bib52","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1001\/archinternmed.2007.124","article-title":"Better outcomes for patients treated at hospitals that participate in clinical trials","volume":"168","author":"Majumdar","year":"2008","journal-title":"Arch Intern Med"}],"container-title":["Value in Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S109830152600077X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S109830152600077X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T21:03:48Z","timestamp":1782507828000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S109830152600077X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":49,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["S109830152600077X"],"URL":"https:\/\/doi.org\/10.1016\/j.jval.2026.02.005","relation":{},"ISSN":["1098-3015"],"issn-type":[{"value":"1098-3015","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cost-Effectiveness of TAVR Compared With Clinical Surveillance in Patients with Asymptomatic Severe Aortic Stenosis in the United States","name":"articletitle","label":"Article Title"},{"value":"Value in Health","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jval.2026.02.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 International Society for Pharmacoeconomics and Outcomes Research, Inc. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}