{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T10:14:32Z","timestamp":1774520072896,"version":"3.50.1"},"reference-count":31,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"90th year Chulalongkorn Scholarship, Graduate School, Chulalongkorn University"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Veterinary Cardiology"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1016\/j.jvc.2014.05.003","type":"journal-article","created":{"date-parts":[[2014,7,28]],"date-time":"2014-07-28T07:30:13Z","timestamp":1406532613000},"page":"155-162","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Plasma and platelet serotonin concentrations in healthy dogs and dogs with myxomatous mitral valve disease"],"prefix":"10.1016","volume":"16","author":[{"given":"Tanawan","family":"Mangklabruks","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sirilak Disatian","family":"Surachetpong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jvc.2014.05.003_bib1","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1016\/j.cvsm.2004.05.002","article-title":"New insights into degenerative mitral valve disease in dogs","volume":"34","author":"H\u00e4ggstr\u00f6m","year":"2004","journal-title":"Vet Clin Small Anim"},{"key":"10.1016\/j.jvc.2014.05.003_bib2","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/j.cvsm.2010.03.008","article-title":"Canine degenerative myxomatous mitral valve disease: natural history, clinical presentation and therapy","volume":"40","author":"Borgarelli","year":"2010","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"10.1016\/j.jvc.2014.05.003_bib3","first-page":"75","article-title":"Chronic valvular disease (endocardiosis) in dogs","volume":"21","author":"Buchanan","year":"1997","journal-title":"Adv Vet Sci Comp Med"},{"key":"10.1016\/j.jvc.2014.05.003_bib4","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/S0008-6363(00)00113-9","article-title":"Mitral valve prolapse in the dog: a model of mitral valve prolapse in man","volume":"47","author":"Pedersen","year":"2000","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.jvc.2014.05.003_bib5","series-title":"Manual of canine and feline cardiology","first-page":"110","article-title":"Acquired valvular disease","author":"Abbott","year":"2008"},{"key":"10.1016\/j.jvc.2014.05.003_bib6","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.2460\/ajvr.67.8.1307","article-title":"Genomic expression pattern of mitral valve tissue from dogs with degenerative mitral valve disease","volume":"67","author":"Oyama","year":"2006","journal-title":"Am J Vet Res"},{"key":"10.1016\/j.jvc.2014.05.003_bib7","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1111\/j.1939-1676.2009.0378.x","article-title":"Serum serotonin concentrations in dogs with degenerative mitral valve disease","volume":"23","author":"Arndt","year":"2009","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.jvc.2014.05.003_bib8","doi-asserted-by":"crossref","first-page":"988","DOI":"10.2353\/ajpath.2009.081101","article-title":"Fenfluramine disrupts the mitral valve interstitial cell response to serotonin","volume":"175","author":"Connolly","year":"2009","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jvc.2014.05.003_bib9","first-page":"44","article-title":"Autocrine serotonin and transforming growth factor \u00df1 signaling mediates spontaneous myxomatous mitral valve disease","volume":"18","author":"Disatian","year":"2009","journal-title":"J Heart Valve Dis"},{"key":"10.1016\/j.jvc.2014.05.003_bib10","first-page":"1","article-title":"Insights into serotonin signaling mechanisms associated with canine degenerative mitral valve disease","volume":"23","author":"Oyama","year":"2009","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.jvc.2014.05.003_bib11","first-page":"R454","article-title":"Comparative study of platelet dense granule constituents","volume":"243","author":"Meyers","year":"1982","journal-title":"Am J Physiol"},{"key":"10.1016\/j.jvc.2014.05.003_bib12","series-title":"Veterinary echocardiography","first-page":"267","article-title":"Acquired valvular disease","author":"Boon","year":"2011"},{"key":"10.1016\/j.jvc.2014.05.003_bib13","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1111\/j.1939-1676.2009.0392.x","article-title":"Guidelines for diagnosis and treatment of canine chronic valvular heart disease","volume":"23","author":"Atkins","year":"2009","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.jvc.2014.05.003_bib14","series-title":"Manual of canine and feline cardiology","first-page":"78","article-title":"Echocardiography and Doppler ultrasound","author":"Fuentes","year":"2008"},{"key":"10.1016\/j.jvc.2014.05.003_bib15","series-title":"Proceeding of instructions for use serotonin (research) ELISA","author":"Immuno-biological laboratories, Inc","year":"2009"},{"key":"10.1016\/j.jvc.2014.05.003_bib16","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/978-1-60761-500-2_20","article-title":"The serotonin hypothesis of pulmonary hypertension revisited","volume":"661","author":"Maclean","year":"2010","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.jvc.2014.05.003_bib17","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1161\/01.CIR.0000159356.42064.48","article-title":"Long-term serotonin administration induces heart valve disease in rats","volume":"111","author":"Gustafsson","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.jvc.2014.05.003_bib18","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.ijcard.2008.02.019","article-title":"Carcinoid heart disease","volume":"129","author":"Gustafsson","year":"2008","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.jvc.2014.05.003_bib19","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1517\/14740330902931524","article-title":"Serotonergic drugs and valvular heart disease","volume":"8","author":"Rothman","year":"2009","journal-title":"Expert Opin Drug Saf"},{"key":"10.1016\/j.jvc.2014.05.003_bib20","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.jvc.2011.12.002","article-title":"Static and cyclic tensile strain induces myxomatous effector proteins and serotonin in canine mitral valves","volume":"14","author":"Lacerda","year":"2012","journal-title":"J Vet Cardiol"},{"key":"10.1016\/j.jvc.2014.05.003_bib21","doi-asserted-by":"crossref","first-page":"H1983","DOI":"10.1152\/ajpheart.00987.2011","article-title":"Local serotonin mediates cyclic strain-induced phenotype transformation, matrix degradation, and glycosaminoglycan synthesis in cultured sheep mitral valves","volume":"302","author":"Lacerda","year":"2012","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.jvc.2014.05.003_bib22","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1111\/jvim.12137","article-title":"Serum serotonin concentration is associated with severity of myxomatous mitral valve disease in dogs","volume":"27","author":"Ljungvall","year":"2013","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.jvc.2014.05.003_bib23","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1177\/0192623307312707","article-title":"Cardiac valvular pathology: comparative pathology and animal models of acquired cardiac valvular disease","volume":"36","author":"Donnelly","year":"2008","journal-title":"Toxicol Pathol"},{"key":"10.1016\/j.jvc.2014.05.003_bib24","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.jvc.2011.12.001","article-title":"Signaling pathways in mitral valve degeneration","volume":"14","author":"Orton","year":"2012","journal-title":"J Vet Cardiol"},{"key":"10.1016\/j.jvc.2014.05.003_bib25","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1007\/s10517-009-0527-x","article-title":"Increased concentrations of serotonin and 5-hydroxyindoleacetic acid in blood plasma from patients with pulmonary hypertension due to mitral valve disease","volume":"147","author":"Kitillova","year":"2009","journal-title":"Bull Exp Biol Med"},{"key":"10.1016\/j.jvc.2014.05.003_bib26","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1212\/WNL.33.3.384","article-title":"Platelet activation and mitral valve prolapse","volume":"33","author":"Fisher","year":"1983","journal-title":"Neurology"},{"key":"10.1016\/j.jvc.2014.05.003_bib27","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/j.1939-1676.2001.tb02313.x","article-title":"Increased platelet aggregation response in Cavalier King Charles spaniels with mitral valve prolapse","volume":"15","author":"Olsen","year":"2001","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.jvc.2014.05.003_bib28","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1146\/annurev.ph.44.030182.001413","article-title":"The fate of circulating amines within the pulmonary circulation","volume":"44","author":"Gillis","year":"1982","journal-title":"Annu Rev Physiol"},{"key":"10.1016\/j.jvc.2014.05.003_bib29","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.yjmcc.2008.12.019","article-title":"Platelet derived serotonin drives the activation of rat cardiac fibroblasts by 5-HT2A receptors","volume":"46","author":"Yabanoglu","year":"2009","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.jvc.2014.05.003_bib30","doi-asserted-by":"crossref","first-page":"198","DOI":"10.2460\/ajvr.2004.65.198","article-title":"Identification of surface morphologic changes in the mitral valve leaflets and chordae tendinae of dogs with myxomatous degeneration","volume":"65","author":"Corcoran","year":"2004","journal-title":"Am J Vet Res"},{"key":"10.1016\/j.jvc.2014.05.003_bib31","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/0002-9149(89)90543-2","article-title":"Scanning electron microscopy of operatively excised severely regurgitant floppy mitral valves","volume":"64","author":"Stein","year":"1989","journal-title":"Am J Cardiol"}],"container-title":["Journal of Veterinary Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1760273414000472?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1760273414000472?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T09:26:58Z","timestamp":1538386018000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1760273414000472"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":31,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["S1760273414000472"],"URL":"https:\/\/doi.org\/10.1016\/j.jvc.2014.05.003","relation":{},"ISSN":["1760-2734"],"issn-type":[{"value":"1760-2734","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Plasma and platelet serotonin concentrations in healthy dogs and dogs with myxomatous mitral valve disease","name":"articletitle","label":"Article Title"},{"value":"Journal of Veterinary Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jvc.2014.05.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}