{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T16:11:28Z","timestamp":1770221488089,"version":"3.49.0"},"reference-count":47,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Veterinary Cardiology"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1016\/j.jvc.2017.08.005","type":"journal-article","created":{"date-parts":[[2017,9,25]],"date-time":"2017-09-25T11:17:32Z","timestamp":1506338252000},"page":"421-432","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Heart rate turbulence after ventricular premature beats in healthy Doberman pinschers and those with dilated cardiomyopathy"],"prefix":"10.1016","volume":"19","author":[{"given":"J.D.","family":"Harris","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.J.L.","family":"Little","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.M.","family":"Dennis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.W.","family":"Patteson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jvc.2017.08.005_bib1","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1161\/CIRCHEARTFAILURE.108.772756","article-title":"The \u201cModern\u201d view of heart failure: How did we get here?","volume":"1","author":"Katz","year":"2008","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.jvc.2017.08.005_bib2","series-title":"Heart Rate Variability","first-page":"3","article-title":"The control and physiologic importance of heart rate","author":"Hainsworth","year":"1995"},{"key":"10.1016\/j.jvc.2017.08.005_bib3","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1093\/oxfordjournals.eurheartj.a014868","article-title":"Heart rate variability: standards of measurement, physiological interpretation and clinical use","volume":"17","author":"Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology","year":"1996","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jvc.2017.08.005_bib4","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1136\/hrt.67.6.482","article-title":"Decreased cardiac parasympathetic activity in chronic heart failure and its relation to left ventricular function","volume":"67","author":"Nolan","year":"1992","journal-title":"Br Heart J"},{"key":"10.1016\/j.jvc.2017.08.005_bib5","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/0002-9149(87)90795-8","article-title":"Decreased heart rate variability and its association with increased mortality after acute myocardial infarction","volume":"59","author":"Kleiger","year":"1987","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jvc.2017.08.005_bib6","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/0735-1097(91)90602-6","article-title":"Parasympathetic withdrawal is an integral component of autonomic imbalance in congestive heart failure: demonstration in human subjects and verification in a paced canine model of ventricular failure","volume":"18","author":"Binkley","year":"1991","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jvc.2017.08.005_bib7","article-title":"Heart rate variability in the dog: is it too variable?","volume":"61","author":"Minors","year":"1997","journal-title":"Can J Vet Res"},{"key":"10.1016\/j.jvc.2017.08.005_bib8","doi-asserted-by":"crossref","first-page":"506","DOI":"10.2460\/ajvr.2000.61.506","article-title":"Heart rate variability in Doberman pinschers with and without echocardiographic evidence of dilated cardiomyopathy","volume":"61","author":"Calvert","year":"2000","journal-title":"Am J Vet Res"},{"key":"10.1016\/j.jvc.2017.08.005_bib9","doi-asserted-by":"crossref","first-page":"534","DOI":"10.2460\/javma.2004.224.534","article-title":"Assessment of heart rate variability in boxers with arrhythmogenic right ventricular cardiomyopathy","volume":"224","author":"Spier","year":"2004","journal-title":"J Am Vet Med Assoc"},{"key":"10.1016\/j.jvc.2017.08.005_bib10","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1016\/S0195-5616(98)50129-5","article-title":"Heart rate variability","volume":"28","author":"Calvert","year":"1998","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"10.1016\/j.jvc.2017.08.005_bib11","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.jacc.2009.03.061","article-title":"Sympathetic nervous system activation in human heart failure","volume":"54","author":"Floras","year":"2009","journal-title":"J Am Coll Card"},{"key":"10.1016\/j.jvc.2017.08.005_bib12","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1016\/S0140-6736(98)08428-1","article-title":"Heart-rate turbulence after ventricular premature beats as a predictor of mortality after acute myocardial infarction","volume":"353","author":"Schmidt","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.jvc.2017.08.005_bib13","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1161\/01.CIR.11.2.240","article-title":"The effect of ventricular systole on auricular rhythm in auriculoventricular block","volume":"11","author":"Rosenbaum","year":"1955","journal-title":"Circulation"},{"key":"10.1016\/j.jvc.2017.08.005_bib14","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1093\/eurheartj\/8.7.762","article-title":"Time course of vagal effects studied in clinical electrocardiograms","volume":"8","author":"Jedlicka","year":"1987","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jvc.2017.08.005_bib15","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S0002-9149(01)02198-1","article-title":"Heart rate turbulence-based predictors of fatal and nonfatal cardiac arrest (The Autonomic Tone and Reflexes after Myocardial Infarction substudy)","volume":"89","author":"Ghuran","year":"2002","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jvc.2017.08.005_bib16","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1081\/CEH-48872","article-title":"Correlation of heart rate turbulence with sympathovagal balance in patients with acute myocardial infarction","volume":"27","author":"Iwasaki","year":"2005","journal-title":"Clin Exp Hypertens"},{"key":"10.1016\/j.jvc.2017.08.005_bib17","doi-asserted-by":"crossref","first-page":"469","DOI":"10.2478\/v10181-012-0072-9","article-title":"Heart rate turbulence in healthy dogs and dogs with dilated cardiomyopathy","volume":"15","author":"Noszczyk-Nowak","year":"2012","journal-title":"Pol J Vet Sci"},{"key":"10.1016\/j.jvc.2017.08.005_bib18","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1111\/j.1939-1676.2010.0575.x","article-title":"Use of Simpson's method of disc to detect early echocardiographic changes in Doberman pinschers with dilated cardiomyopathy","volume":"24","author":"Wess","year":"2010","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.jvc.2017.08.005_bib19","doi-asserted-by":"crossref","first-page":"782","DOI":"10.2460\/javma.2001.219.782","article-title":"Results of ambulatory electrocardiography in overtly healthy Doberman pinschers with equivocal evidence of dilated cardiomyopathy","volume":"219","author":"Calvert","year":"2001","journal-title":"J Am Vet Med Assoc"},{"key":"10.1016\/j.jvc.2017.08.005_bib20","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1111\/j.1939-1676.2012.01026.x","article-title":"Efficacy of pimobendan in the prevention of congestive heart failure or sudden death in Doberman pinschers with preclinical dilated cardiomyopathy (The PROTECT Study)","volume":"26","author":"Summerfield","year":"2012","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.jvc.2017.08.005_bib21","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1046\/j.1540-8167.2003.03085.x","article-title":"Prognostic significance of heart rate turbulence following ventricular premature beats in patients with idiopathic dilated cardiomyopathy","volume":"14","author":"Grimm","year":"2003","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.jvc.2017.08.005_bib22","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1093\/europace\/eul059","article-title":"Heart rate turbulence and heart rate variability in patients with mitral valve prolapse","volume":"8","author":"Gunduz","year":"2006","journal-title":"Europace"},{"key":"10.1016\/j.jvc.2017.08.005_bib23","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1016\/j.hrthm.2008.04.017","article-title":"Heart rate turbulence predicts all-cause mortality and sudden death in congestive heart failure patients","volume":"5","author":"Cygankiewicz","year":"2008","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.jvc.2017.08.005_bib24","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1016\/j.jacc.2008.07.041","article-title":"Heart rate turbulence: standards of measurement, physiological interpretation, and clinical use: International Society for Holter and Noninvasive Electrophysiology Consensus","volume":"52","author":"Bauer","year":"2008","journal-title":"JACC"},{"key":"10.1016\/j.jvc.2017.08.005_bib25","series-title":"Clinical Guide to Cardiac Autonomic Tests","first-page":"3","article-title":"Physiology of the cardiac autonomic nervous system","author":"Hainsworth","year":"1998"},{"key":"10.1016\/j.jvc.2017.08.005_bib26","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S1760-2734(06)70047-9","article-title":"Proposed guidelines for the diagnosis of canine idiopathic dilated cardiomyopathy","volume":"5","author":"Dukes McEwan","year":"2003","journal-title":"J Vet Cardiol"},{"key":"10.1016\/j.jvc.2017.08.005_bib27","series-title":"Textbook of Veterinary Internal Medicine","first-page":"p1320","article-title":"Myocardial disease: canine","author":"Meurs","year":"2010"},{"key":"10.1016\/j.jvc.2017.08.005_bib28","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1111\/jvim.13941","article-title":"Predictors of sudden cardiac death in Doberman pinschers with dilated cardiomyopathy","volume":"30","author":"Kl\u00fcser","year":"2016","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.jvc.2017.08.005_bib29","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1111\/j.1939-1676.2010.0479.x","article-title":"Prevalence of dilated cardiomyopathy in Doberman Pinschers in various age groups","volume":"24","author":"Wess","year":"2010","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.jvc.2017.08.005_bib30","first-page":"199","article-title":"The prevalence of dilated cardiomyopathy in Doberman Pinschers: a 4.5 year follow-up","volume":"12","author":"O'Grady","year":"1998","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.jvc.2017.08.005_bib31","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.2460\/javma.2001.219.1084","article-title":"Effect of severity of myocardial failure on heart rate variability in Doberman pinschers with and without echocardiographic evidence of dilated cardiomyopathy","volume":"219","author":"Calvert","year":"2001","journal-title":"J Am Vet Med Assoc"},{"key":"10.1016\/j.jvc.2017.08.005_bib32","first-page":"H758","article-title":"Real-time measurement of cardiac vagal tone in conscious dogs","volume":"276","author":"Little","year":"1999","journal-title":"Am J Physiol"},{"key":"10.1016\/j.jvc.2017.08.005_bib33","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1136\/vr.156.4.101","article-title":"Non-invasive real-time measurements of cardiac vagal tone in dogs with cardiac disease","volume":"156","author":"Little","year":"2005","journal-title":"Vet Rec"},{"key":"10.1016\/j.jvc.2017.08.005_bib34","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/j.1748-5827.1996.tb01941.x","article-title":"Heart rate variability in relation to severity of mitral regurgitation in Cavalier King Charles Spaniels","volume":"37","author":"Haggstrom","year":"1996","journal-title":"J Small Anim Pract"},{"key":"10.1016\/j.jvc.2017.08.005_bib35","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1111\/j.1748-5827.2008.00654.x","article-title":"The vasovagal tonus index as a prognostic indicator in dogs with dilated cardiomyopathy","volume":"49","author":"Martinez Pereira","year":"2008","journal-title":"J Small Anim Pract"},{"key":"10.1016\/j.jvc.2017.08.005_bib36","doi-asserted-by":"crossref","first-page":"477","DOI":"10.2478\/v10181-012-0073-8","article-title":"Heart rate turbulence in mild-to-moderate aortic stenosis in boxers","volume":"15","author":"Noszczyk-Nowak","year":"2012","journal-title":"Pol J Vet Sci"},{"key":"10.1016\/j.jvc.2017.08.005_bib37","first-page":"162","article-title":"Short-term heart rate turbulence analysis versus variability and baroreceptor sensitivity in patients with dilated cardiomyopathy","volume":"4","author":"Malberg","year":"2004","journal-title":"Indian Pacing Electrophysiol J"},{"key":"10.1016\/j.jvc.2017.08.005_bib38","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1253\/circj.66.902","article-title":"Evaluation of heart-rate turbulence as a new prognostic marker in patients with chronic heart failure","volume":"66","author":"Koyama","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.jvc.2017.08.005_bib39","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1023\/A:1007785314462","article-title":"Effects of long-term digoxin therapy on heart rate variability, baroreceptor sensitivity, and exercise capacity in patients with heart failure","volume":"12","author":"Vardas","year":"1998","journal-title":"Cardiovasc Drugs Ther"},{"key":"10.1016\/j.jvc.2017.08.005_bib40","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1046\/j.1540-8167.2004.03289.x","article-title":"Restoration of heart rate turbulence by titrated beta-blocker therapy in patients with advanced congestive heart failure: positive correlation with enhanced vagal modulation of heart rate","volume":"15","author":"Lin","year":"2004","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.jvc.2017.08.005_bib41","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/S0002-9149(03)00968-8","article-title":"Temporal changes and prognostic significance of measures of heart rate dynamics after acute myocardial infarction in the beta-blocking era","volume":"92","author":"Jokinen","year":"2003","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jvc.2017.08.005_bib42","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/S0735-1097(97)00554-8","article-title":"Twenty-four hour time domain variability and heart rate: relations to age and gender over nine decades","volume":"31","author":"Umentani","year":"1998","journal-title":"JACC"},{"issue":"Suppl. 1","key":"10.1016\/j.jvc.2017.08.005_bib43","doi-asserted-by":"crossref","first-page":"S198","DOI":"10.1111\/j.1540-8159.2005.00042.x","article-title":"Impact of age and basic heart rate on heart rate turbulence in healthy persons","volume":"28","author":"Schwab","year":"2005","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.jvc.2017.08.005_bib44","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S1760-2734(06)70029-7","article-title":"Heart rate variability in young, clinically healthy Dachshunds: influence of sex, mitral valve prolapse status, sampling period and time of day","volume":"1","author":"Olsen","year":"1999","journal-title":"J Vet Cardiol"},{"key":"10.1016\/j.jvc.2017.08.005_bib45","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1111\/jsap.12079","article-title":"Relationships between heart rate and age, bodyweight and breed in 10,849 dogs","volume":"54","author":"Hezzell","year":"2013","journal-title":"J Small Anim Pract"},{"key":"10.1016\/j.jvc.2017.08.005_bib46","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1161\/01.CIR.0000088783.34082.89","article-title":"Risk stratification after acute myocardial infarction by heart rate turbulence","volume":"108","author":"Barthel","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.jvc.2017.08.005_bib47","doi-asserted-by":"crossref","first-page":"31","DOI":"10.2143\/AC.62.1.2019368","article-title":"Prognostic value of heart rate turbulence and heart rate variability in children with dilated cardiomyopathy","volume":"62","author":"Karakurt","year":"2007","journal-title":"Acta Cardiol"}],"container-title":["Journal of Veterinary Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1760273416300868?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1760273416300868?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,10,3]],"date-time":"2019-10-03T19:13:16Z","timestamp":1570129996000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1760273416300868"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":47,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["S1760273416300868"],"URL":"https:\/\/doi.org\/10.1016\/j.jvc.2017.08.005","relation":{},"ISSN":["1760-2734"],"issn-type":[{"value":"1760-2734","type":"print"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Heart rate turbulence after ventricular premature beats in healthy Doberman pinschers and those with dilated cardiomyopathy","name":"articletitle","label":"Article Title"},{"value":"Journal of Veterinary Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jvc.2017.08.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}