{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T15:10:53Z","timestamp":1792595453443,"version":"4.5.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2007,10,1]],"date-time":"2007-10-01T00:00:00Z","timestamp":1191196800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Vascular and Interventional Radiology"],"published-print":{"date-parts":[[2007,10]]},"DOI":"10.1016\/j.jvir.2007.06.028","type":"journal-article","created":{"date-parts":[[2007,10,2]],"date-time":"2007-10-02T17:13:56Z","timestamp":1191345236000},"page":"1249-1257","source":"Crossref","is-referenced-by-count":69,"title":["A Comparison of Chemoembolization Endpoints Using Angiographic versus Transcatheter Intraarterial Perfusion\/MR Imaging Monitoring"],"prefix":"10.1016","volume":"18","author":[{"given":"Robert J.","family":"Lewandowski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dingxin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Gehl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bassel","family":"Atassi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert K.","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kent","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Albert A.","family":"Nemcek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank H.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary F.","family":"Mulcahy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Kulik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew C.","family":"Larson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riad","family":"Salem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reed A.","family":"Omary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jvir.2007.06.028_bib1","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1001\/archsurg.1996.01430150070014","article-title":"Multimodality treatment of hepatocellular carcinoma in a hepatobiliary specialty center","volume":"131","author":"Marcos-Alvarez","year":"1996","journal-title":"Arch Surg"},{"key":"10.1016\/j.jvir.2007.06.028_bib2","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1308\/003588403769162468","article-title":"Liver resection for colorectal metastases","volume":"85","author":"Bramhall","year":"2003","journal-title":"Ann R Coll Surg Engl"},{"key":"10.1016\/j.jvir.2007.06.028_bib3","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1002\/hep.1840160119","article-title":"Prognostic factors in patients with hepatocellular carcinoma receiving systemic chemotherapy","volume":"16","author":"Okada","year":"1992","journal-title":"Hepatology"},{"key":"10.1016\/j.jvir.2007.06.028_bib4","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1093\/oxfordjournals.annonc.a058560","article-title":"Prognostic factors in patients affected by hepatocellular carcinoma treated with systemic chemotherapy: the experience of the National Cancer Institute of Milan","volume":"4","author":"Colleoni","year":"1993","journal-title":"Ann Oncol"},{"key":"10.1016\/j.jvir.2007.06.028_bib5","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/s00280-002-0503-x","article-title":"Treatment of hepatocellular carcinoma (HCC) with systemic chemotherapy combining epirubicin, cisplatinum and infusional 5-fluorouracil (ECF regimen)","volume":"50","author":"Boucher","year":"2002","journal-title":"Cancer Chemother Pharmacol"},{"key":"10.1016\/j.jvir.2007.06.028_bib6","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1002\/hep.510310111","article-title":"Randomized controlled trial of interferon treatment for advanced hepatocellular carcinoma","volume":"31","author":"Llovet","year":"2000","journal-title":"Hepatology"},{"key":"10.1016\/j.jvir.2007.06.028_bib7","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1053\/jhep.2002.36824","article-title":"High-dose tamoxifen in the treatment of inoperable hepatocellular carcinoma: a multicenter randomized controlled trial","volume":"36","author":"Chow","year":"2002","journal-title":"Hepatology"},{"key":"10.1016\/j.jvir.2007.06.028_bib8","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1002\/1097-0142(19880801)62:3<479::AID-CNCR2820620306>3.0.CO;2-L","article-title":"Doxorubicin versus no antitumor therapy in inoperable hepatocellular carcinoma: a prospective randomized trial","volume":"62","author":"Lai","year":"1988","journal-title":"Cancer"},{"key":"10.1016\/j.jvir.2007.06.028_bib9","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/s11864-005-0045-7","article-title":"Management of hepatocellular cancer","volume":"6","author":"Mulcahy","year":"2005","journal-title":"Curr Treat Options Oncol"},{"key":"10.1016\/j.jvir.2007.06.028_bib10","doi-asserted-by":"crossref","first-page":"1734","DOI":"10.1016\/S0140-6736(02)08649-X","article-title":"Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial","volume":"359","author":"Llovet","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.jvir.2007.06.028_bib11","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1053\/jhep.2002.33156","article-title":"Randomized controlled trial of transarterial lipiodol chemoembolization for unresectable hepatocellular carcinoma","volume":"35","author":"Lo","year":"2002","journal-title":"Hepatology"},{"key":"10.1016\/j.jvir.2007.06.028_bib12","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1001\/jama.1988.03410070102037","article-title":"Regression of ocular melanoma metastatic to the liver after hepatic arterial chemoembolization with cisplatin and polyvinyl sponge","volume":"260","author":"Mavligit","year":"1988","journal-title":"JAMA"},{"key":"10.1016\/j.jvir.2007.06.028_bib13","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1002\/(SICI)1097-0142(19980401)82:7<1250::AID-CNCR7>3.0.CO;2-J","article-title":"Phase II trial of chemoembolization for the treatment of metastatic colorectal carcinoma to the liver and review of the literature","volume":"82","author":"Tellez","year":"1998","journal-title":"Cancer"},{"key":"10.1016\/j.jvir.2007.06.028_bib14","first-page":"77","article-title":"Chemoembolization of hepatic malignancies","volume":"8","author":"Soulen","year":"1994","journal-title":"Oncology (Williston Park)"},{"key":"10.1016\/j.jvir.2007.06.028_bib15","doi-asserted-by":"crossref","first-page":"173","DOI":"10.3816\/CCC.2002.n.022","article-title":"Randomized phase II trial of embolization therapy versus chemoembolization therapy in previously treated patients with colorectal carcinoma metastatic to the liver","volume":"2","author":"Salman","year":"2002","journal-title":"Clin Colorectal Cancer"},{"key":"10.1016\/j.jvir.2007.06.028_bib16","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1148\/radiology.189.2.7692465","article-title":"Transcatheter chemoembolization of progressive carcinoid liver metastasis","volume":"189","author":"Therasse","year":"1993","journal-title":"Radiology"},{"key":"10.1016\/j.jvir.2007.06.028_bib17","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S1051-0443(93)71871-0","article-title":"Hepatic arterial chemoembolization for metastatic endocrine tumors","volume":"4","author":"Stokes","year":"1993","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2007.06.028_bib18","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1097\/00130404-200307000-00008","article-title":"Hepatic artery embolization and chemoembolization for treatment of patients with metastatic carcinoid tumors: the M.D. Anderson experience","volume":"9","author":"Gupta","year":"2003","journal-title":"Cancer J"},{"key":"10.1016\/j.jvir.2007.06.028_bib19","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1097\/01.RVI.0000116190.44877.04","article-title":"Chemoembolization of liver metastasis from breast carcinoma","volume":"15","author":"Giroux","year":"2004","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2007.06.028_bib20","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S1051-0443(07)61824-7","article-title":"Sarcomas metastatic to the liver: response and survival after cisplatin, doxorubicin, mitomycin-C, Ethiodol, and polyvinyl alcohol chemoembolization","volume":"12","author":"Rajan","year":"2001","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2007.06.028_bib21","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1097\/01.RVI.0000196277.76812.A3","article-title":"Society of Interventional Radiology position statement on chemoembolization of hepatic malignancies","volume":"17","author":"Brown","year":"2006","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2007.06.028_bib22","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s00270-002-2524-6","article-title":"Transcatheter arterial chemoembolization of liver tumors: effects of embolization protocol on injectable volume of chemotherapy and subsequent arterial patency","volume":"26","author":"Geschwind","year":"2003","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.jvir.2007.06.028_bib23","unstructured":"Larson A WD, Atassi B, Sato K, et al. Transcatheter intraarterial first-pass perfusion (TRIP)\u2014MRI monitoring of chemoembolization for hepatocellular carcinoma. Radiology 2007 (in press)."},{"key":"10.1016\/j.jvir.2007.06.028_bib24","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1097\/01.RVI.0000195330.47954.48","article-title":"Quality improvement guidelines for transhepatic arterial chemoembolization, embolization, and chemotherapeutic infusion for hepatic malignancy","volume":"17","author":"Brown","year":"2006","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2007.06.028_bib25","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1097\/01.RVI.0000182185.47500.7A","article-title":"Safety and efficacy of transarterial chemoembolization in patients with unresectable hepatocellular carcinoma and portal vein thrombosis","volume":"16","author":"Georgiades","year":"2005","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2007.06.028_bib26","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S0168-8278(01)00130-1","article-title":"Clinical management of hepatocellular carcinoma","volume":"35","author":"Bruix","year":"2001","journal-title":"J Hepatol"},{"key":"10.1016\/j.jvir.2007.06.028_bib27","first-page":"1747","article-title":"Usefulness of alpha-fetoprotein in the diagnosis of hepatocellular carcinoma","volume":"23","author":"Soresi","year":"2003","journal-title":"Anticancer Res"},{"key":"10.1016\/j.jvir.2007.06.028_bib28","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1002\/mrm.10045","article-title":"Assessment of hepatic perfusion parameters with dynamic MRI","volume":"47","author":"Materne","year":"2002","journal-title":"Magn Reson Med"},{"key":"10.1016\/j.jvir.2007.06.028_bib29","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1056\/NEJM198504043121437","article-title":"The Thrombolysis in Myocardial Infarction (TIMI) trial","volume":"312","year":"1985","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jvir.2007.06.028_bib30","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1097\/01.RVI.0000182160.26798.A2","article-title":"Hepatic arterial chemoembolization for hepatocellular carcinoma: comparison of survival rates with different embolic agents","volume":"16","author":"Brown","year":"2005","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2007.06.028_bib31","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1097\/01.RVI.0000184535.26360.5A","article-title":"Effects of the type of embolization particles on carboplatin concentration in liver tumors after transcatheter arterial chemoembolization in a rabbit model of liver cancer","volume":"16","author":"Hong","year":"2005","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2007.06.028_bib32","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1478-3231.1999.tb00005.x","article-title":"Co-expression of Bcl-2 protein and vascular endothelial growth factor in hepatocellular carcinomas treated by chemoembolization","volume":"19","author":"Kobayashi","year":"1999","journal-title":"Liver"},{"key":"10.1016\/j.jvir.2007.06.028_bib33","first-page":"386","article-title":"Association between vascular endothelial growth factor and metastasis after transcatheter arterial chemoembolization in patients with hepatocellular carcinoma","volume":"3","author":"Xiong","year":"2004","journal-title":"Hepatobiliary Pancreat Dis Int"},{"key":"10.1016\/j.jvir.2007.06.028_bib34","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.jvir.2007.02.031","article-title":"Effect of transcatheter arterial embolization on levels of hypoxia inducible factor-1 alpha in rabbit VX2 liver tumors","volume":"18","author":"Rhee","year":"2007","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2007.06.028_bib35","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.jhep.2004.11.020","article-title":"Hypoxia stimulates proliferation of human hepatoma cells through the induction of hexokinase II expression","volume":"42","author":"Gwak","year":"2005","journal-title":"J Hepatol"},{"key":"10.1016\/j.jvir.2007.06.028_bib36","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.jvir.2006.10.019","article-title":"Intraarterial therapy with a new potent inhibitor of tumor metabolism (3-bromopyruvate): identification of therapeutic dose and method of injection in an animal model of liver cancer","volume":"18","author":"Vali","year":"2007","journal-title":"J Vasc Interv Radiol"}],"container-title":["Journal of Vascular and Interventional Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1051044307009773?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1051044307009773?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,3]],"date-time":"2019-05-03T13:37:45Z","timestamp":1556890665000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1051044307009773"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,10]]},"references-count":36,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2007,10]]}},"alternative-id":["S1051044307009773"],"URL":"https:\/\/doi.org\/10.1016\/j.jvir.2007.06.028","relation":{},"ISSN":["1051-0443"],"issn-type":[{"value":"1051-0443","type":"print"}],"subject":[],"published":{"date-parts":[[2007,10]]}}}