{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T23:29:24Z","timestamp":1793316564991,"version":"4.5.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Vascular and Interventional Radiology"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1016\/j.jvir.2016.01.147","type":"journal-article","created":{"date-parts":[[2016,4,9]],"date-time":"2016-04-09T12:30:33Z","timestamp":1460205033000},"page":"812-821.e2","source":"Crossref","is-referenced-by-count":47,"title":["Outcomes of Radioembolization in the Treatment of Hepatocellular Carcinoma with Portal Vein Invasion: Resin versus Glass Microspheres"],"prefix":"10.1016","volume":"27","author":[{"given":"Derek M.","family":"Biederman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph J.","family":"Titano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nora E.","family":"Tabori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa S.","family":"Pierobon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0549-157X","authenticated-orcid":false,"given":"Kutaiba","family":"Alshebeeb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myron","family":"Schwartz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo E.","family":"Facciuto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ganesh","family":"Gunasekaran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sander","family":"Florman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron M.","family":"Fischman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul S.","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis S.","family":"Nowakowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8050-2366","authenticated-orcid":false,"given":"Edward","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jvir.2016.01.147_bib1","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/s004320050189","article-title":"Portal vein thrombosis in hepatocellular carcinoma: age and sex distribution in an autopsy study","volume":"124","author":"Pirisi","year":"1998","journal-title":"J Cancer Res Clin Oncol"},{"key":"10.1016\/j.jvir.2016.01.147_bib2","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1002\/hep.24812","article-title":"Extrahepatic metastases occur in a minority of hepatocellular carcinoma patients treated with locoregional therapies: analyzing patterns of progression in 285 patients","volume":"55","author":"Senthilnathan","year":"2012","journal-title":"Hepatology"},{"key":"10.1016\/j.jvir.2016.01.147_bib3","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1007\/s12072-010-9165-7","article-title":"Asian Pacific Association for the Study of the Liver consensus recommendations on hepatocellular carcinoma","volume":"4","author":"Omata","year":"2010","journal-title":"Hepatol Int"},{"issue":"Suppl 5","key":"10.1016\/j.jvir.2016.01.147_bib4","doi-asserted-by":"crossref","first-page":"v59","DOI":"10.1093\/annonc\/mdq166","article-title":"ESMO Guidelines Working Group. Hepatocellular carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up","volume":"21","author":"Jelic","year":"2010","journal-title":"Ann Oncol"},{"key":"10.1016\/j.jvir.2016.01.147_bib5","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1053\/j.gastro.2009.09.006","article-title":"Radioembolization for hepatocellular carcinoma using Yttrium-90 microspheres: a comprehensive report of long-term outcomes","volume":"138","author":"Salem","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jvir.2016.01.147_bib6","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1053\/j.gastro.2010.10.049","article-title":"Radioembolization results in longer time-to-progression and reduced toxicity compared with chemoembolization in patients with hepatocellular carcinoma","volume":"140","author":"Salem","year":"2011","journal-title":"Gastroenterology"},{"issue":"5 Suppl 1","key":"10.1016\/j.jvir.2016.01.147_bib7","doi-asserted-by":"crossref","first-page":"S194","DOI":"10.1053\/j.gastro.2004.09.034","article-title":"Yttrium-90 microspheres for the treatment of hepatocellular carcinoma","volume":"127","author":"Geschwind","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jvir.2016.01.147_bib8","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.jhep.2012.09.003","article-title":"Radioembolization for hepatocellular carcinoma with portal vein thrombosis: impact of liver function on systemic treatment options at disease progression","volume":"58","author":"Memon","year":"2013","journal-title":"J Hepatol"},{"key":"10.1016\/j.jvir.2016.01.147_bib9","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1159\/000348325","article-title":"Treatment for hepatocellular carcinoma with portal vein tumor thrombosis: the emerging role for radioembolization using yttrium-90","volume":"84","author":"Lau","year":"2013","journal-title":"Oncology"},{"key":"10.1016\/j.jvir.2016.01.147_bib10","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1002\/hep.21980","article-title":"Safety and efficacy of 90Y radiotherapy for hepatocellular carcinoma with and without portal vein thrombosis","volume":"47","author":"Kulik","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.jvir.2016.01.147_bib11","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1097\/01.RVI.0000233785.75257.9A","article-title":"Radioembolization with 90Yttrium microspheres: a state-of-the-art brachytherapy treatment for primary and secondary liver malignancies. Part 1: technical and methodologic considerations","volume":"17","author":"Salem","year":"2006","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2016.01.147_bib12","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1002\/hep.27057","article-title":"Unresectable solitary hepatocellular carcinoma not amenable to radiofrequency ablation: multicenter radiology-pathology correlation and survival of radiation segmentectomy","volume":"60","author":"Vouche","year":"2014","journal-title":"Hepatology"},{"key":"10.1016\/j.jvir.2016.01.147_bib13","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1007\/s00330-008-1211-7","article-title":"Yttrium-90 microsphere radioembolization for the treatment of liver malignancies: a structured meta-analysis","volume":"19","author":"Vente","year":"2009","journal-title":"Eur Radiol"},{"key":"10.1016\/j.jvir.2016.01.147_bib14","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1002\/hep.24199","article-title":"Management of hepatocellular carcinoma: an update","volume":"53","author":"Bruix","year":"2011","journal-title":"Hepatology"},{"key":"10.1016\/j.jvir.2016.01.147_bib15","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1002\/hep.20933","article-title":"Management of hepatocellular carcinoma","volume":"42","author":"Bruix","year":"2005","journal-title":"Hepatology"},{"key":"10.1016\/j.jvir.2016.01.147_bib16","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.jvir.2010.10.029","article-title":"Research reporting standards for radioembolization of hepatic malignancies","volume":"22","author":"Salem","year":"2011","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2016.01.147_bib17","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1007\/s00270-007-9064-z","article-title":"Radioembolization with 90Y microspheres: angiographic and technical considerations","volume":"30","author":"Lewandowski","year":"2007","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.jvir.2016.01.147_bib18","first-page":"37s","article-title":"MIRD pamphlet no. 16: techniques for quantitative radiopharmaceutical biodistribution data acquisition and analysis for use in human radiation dose estimates","volume":"40","author":"Siegel","year":"1999","journal-title":"J Nucl Med"},{"key":"10.1016\/j.jvir.2016.01.147_bib19","series-title":"Common terminology criteria for adverse events (CTCAE), version 4.03","year":"2010"},{"key":"10.1016\/j.jvir.2016.01.147_bib20","unstructured":"Centers for Disease Control and Prevention. National death index. 2014. Available at: http:\/\/www.cdc.gov\/nchs\/ndi.htm. Accessed September 1, 2014."},{"key":"10.1016\/j.jvir.2016.01.147_bib21","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1080\/01621459.1999.10474144","article-title":"A proportional hazards model for the subdistribution of a competing risk","volume":"94","author":"Fine","year":"1999","journal-title":"J Am Stat Assoc"},{"key":"10.1016\/j.jvir.2016.01.147_bib22","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1046\/j.1440-1746.2001.02496.x","article-title":"Radiation therapy in combination with transcatheter arterial chemoembolization for hepatocellular carcinoma with extensive portal vein involvement","volume":"16","author":"Tazawa","year":"2001","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.jvir.2016.01.147_bib23","doi-asserted-by":"crossref","first-page":"28","DOI":"10.3748\/wjg.v7.i1.28","article-title":"Multimodality treatment in hepatocellular carcinoma patients with tumor thrombi in portal vein","volume":"7","author":"Fan","year":"2001","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.jvir.2016.01.147_bib24","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1002\/hep.24451","article-title":"European Network on Radioembolization with Yttrium-90 Resin Microspheres (ENRY). Survival after yttrium-90 resin microsphere radioembolization of hepatocellular carcinoma across Barcelona clinic liver cancer stages: a European evaluation","volume":"54","author":"Sangro","year":"2011","journal-title":"Hepatology"},{"key":"10.1016\/j.jvir.2016.01.147_bib25","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1002\/hep.22747","article-title":"Radiologic-pathologic correlation of hepatocellular carcinoma treated with internal radiation using yttrium-90 microspheres","volume":"49","author":"Riaz","year":"2009","journal-title":"Hepatology"},{"key":"10.1016\/j.jvir.2016.01.147_bib26","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1002\/hep.23944","article-title":"Radioembolization with yttrium-90 glass microspheres in hepatocellular carcinoma: European experience on safety and long-term survival","volume":"52","author":"Hilgard","year":"2010","journal-title":"Hepatology"},{"key":"10.1016\/j.jvir.2016.01.147_bib27","doi-asserted-by":"crossref","first-page":"2164","DOI":"10.1002\/cncr.29275","article-title":"Open-label prospective study of the safety and efficacy of glass-based yttrium 90 radioembolization for infiltrative hepatocellular carcinoma with portal vein thrombosis","volume":"121","author":"Kokabi","year":"2015","journal-title":"Cancer"},{"key":"10.1016\/j.jvir.2016.01.147_bib28","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1007\/s00270-013-0579-1","article-title":"Root cause analysis of gastroduodenal ulceration after yttrium-90 radioembolization","volume":"36","author":"Lam","year":"2013","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.jvir.2016.01.147_bib29","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/s13550-015-0133-z","article-title":"Evaluation of the delivered activity of yttrium-90 resin microspheres using sterile water and 5% glucose during administration","volume":"5","author":"Ahmadzadehfar","year":"2015","journal-title":"EJNMMI Res"}],"container-title":["Journal of Vascular and Interventional Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1051044316002013?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1051044316002013?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,13]],"date-time":"2018-09-13T10:22:43Z","timestamp":1536834163000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1051044316002013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["S1051044316002013"],"URL":"https:\/\/doi.org\/10.1016\/j.jvir.2016.01.147","relation":{},"ISSN":["1051-0443"],"issn-type":[{"value":"1051-0443","type":"print"}],"subject":[],"published":{"date-parts":[[2016,6]]}}}