{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T20:21:21Z","timestamp":1790713281994,"version":"4.1.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jvir.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Vascular and Interventional Radiology"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.jvir.2023.05.026","type":"journal-article","created":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T12:08:28Z","timestamp":1684411708000},"page":"1547-1555","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Radioembolization with Yttrium-90 Glass Microspheres as a First-Line Treatment for Unresectable Intrahepatic Cholangiocarcinoma\u2014A Prospective Feasibility Study"],"prefix":"10.1016","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8898-650X","authenticated-orcid":false,"given":"Bela","family":"Kis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravi","family":"Shridhar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul","family":"Mhaskar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6237-6175","authenticated-orcid":false,"given":"Marcell","family":"Gyano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1901-0933","authenticated-orcid":false,"given":"Jessica M.","family":"Frakes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghassan","family":"El-Haddad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junsung","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard D.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah E.","family":"Hoffe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jvir.2023.05.026_bib1","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.canlet.2015.09.008","article-title":"Intrahepatic cholangiocarcinoma: epidemiology, risk factors, diagnosis and surgical management","volume":"379","author":"Zhang","year":"2016","journal-title":"Cancer Lett"},{"key":"10.1016\/j.jvir.2023.05.026_bib2","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1245\/s10434-007-9627-x","article-title":"Surgical management of intrahepatic cholangiocarcinoma\u2014a population-based study","volume":"15","author":"Tan","year":"2008","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jvir.2023.05.026_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1056\/EVIDoa2200015","article-title":"Durvalumab plus gemcitabine and cisplatin in advanced biliary tract cancer","volume":"1","author":"Oh","year":"2022","journal-title":"NEJM Evid"},{"key":"10.1016\/j.jvir.2023.05.026_bib4","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1016\/j.jvir.2020.02.008","article-title":"Yttrium-90 radioembolization in intrahepatic cholangiocarcinoma: a multicenter retrospective analysis","volume":"31","author":"Buettner","year":"2020","journal-title":"J\u00a0Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2023.05.026_bib5","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1016\/j.jvir.2018.04.001","article-title":"Intrahepatic cholangiocarcinoma treated with transarterial yttrium-90 glass microsphere radioembolization: results of a single institution retrospective study","volume":"29","author":"Gangi","year":"2018","journal-title":"J\u00a0Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2023.05.026_bib6","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.jvir.2022.10.042","article-title":"Survival and toxicities after yttrium-90 transarterial radioembolization of cholangiocarcinoma in the RESiN registry","volume":"34","author":"Robinson","year":"2023","journal-title":"J\u00a0Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2023.05.026_bib7","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1007\/s00270-017-1871-2","article-title":"Prognostic factors in overall survival of patients with unresectable intrahepatic cholangiocarcinoma treated by means of yttrium-90 radioembolization: results in therapy-naive patients","volume":"41","author":"Reimer","year":"2018","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.jvir.2023.05.026_bib8","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1007\/s00270-020-02569-4","article-title":"Yttrium-90 radioembolization in unresectable intrahepatic cholangiocarcinoma: results of a multicenter retrospective study","volume":"43","author":"Bargellini","year":"2020","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.jvir.2023.05.026_bib9","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1007\/s00270-022-03183-2","article-title":"Yttrium-90 radioembolization of unresectable intrahepatic cholangiocarcinoma: long-term follow-up for a 136-patient cohort","volume":"45","author":"Gupta","year":"2022","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.jvir.2023.05.026_bib10","doi-asserted-by":"crossref","first-page":"529","DOI":"10.2967\/jnumed.122.264598","article-title":"Real-life experience in the treatment of intrahepatic cholangiocarcinoma by 90Y radioembolization: a multicenter retrospective study","volume":"64","author":"Schaarschmidt","year":"2023","journal-title":"J\u00a0Nucl Med"},{"key":"10.1016\/j.jvir.2023.05.026_bib11","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1001\/jamaoncol.2019.3702","article-title":"Radioembolization plus chemotherapy for first-line treatment of locally advanced intrahepatic cholangiocarcinoma: a phase 2 clinical trial","volume":"6","author":"Edeline","year":"2020","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.jvir.2023.05.026_bib12","first-page":"200","article-title":"Advanced intrahepatic cholangiocarcinoma: post hoc analysis of the ABC-01, -02, and -03 clinical trials","volume":"112","author":"Lamarca","year":"2020","journal-title":"J\u00a0Natl Cancer Inst"},{"key":"10.1016\/j.jvir.2023.05.026_bib13","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1053\/j.tvir.2007.08.001","article-title":"Technical aspects of radioembolization with 90Y microspheres","volume":"10","author":"Salem","year":"2007","journal-title":"Tech Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2023.05.026_bib14","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.jvir.2010.10.029","article-title":"Research reporting standards for radioembolization of hepatic malignancies","volume":"22","author":"Salem","year":"2011","journal-title":"J\u00a0Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2023.05.026_bib15","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1002\/jso.24093","article-title":"Multimodality treatment of intrahepatic cholangiocarcinoma: a review","volume":"113","author":"Simo","year":"2016","journal-title":"J\u00a0Surg Oncol"},{"key":"10.1016\/j.jvir.2023.05.026_bib16","doi-asserted-by":"crossref","first-page":"298","DOI":"10.5009\/gnl.2009.3.4.298","article-title":"Natural history and prognostic factors of advanced cholangiocarcinoma without surgery, chemotherapy, or radiotherapy: a large-scale observational study","volume":"3","author":"Park","year":"2009","journal-title":"Gut Liver"},{"key":"10.1016\/j.jvir.2023.05.026_bib17","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.crad.2010.11.002","article-title":"Transarterial chemoembolization versus supportive therapy in the palliative treatment of unresectable intrahepatic cholangiocarcinoma","volume":"66","author":"Park","year":"2011","journal-title":"Clin Radiol"},{"key":"10.1016\/j.jvir.2023.05.026_bib18","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1056\/NEJMoa0908721","article-title":"Cisplatin plus gemcitabine versus\u00a0gemcitabine for biliary tract cancer","volume":"362","author":"Valle","year":"2010","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jvir.2023.05.026_bib19","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1007\/s10620-007-9885-2","article-title":"Phase-II study of gemcitabine and cisplatin in patients with metastatic biliary and gallbladder cancer","volume":"53","author":"Meyerhardt","year":"2008","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.jvir.2023.05.026_bib20","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.jhep.2020.03.007","article-title":"Molecular targeted therapies: ready for \u201cprime time\u201d in biliary tract cancer","volume":"73","author":"Lamarca","year":"2020","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jvir.2023.05.026_bib21","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1159\/000525489","article-title":"Selective internal radiation therapy with yttrium-90 resin microspheres followed by gemcitabine plus cisplatin for unresectable intrahepatic cholangiocarcinoma: a phase 2 single-arm multicenter clinical trial","volume":"11","author":"Chan","year":"2022","journal-title":"Liver Cancer"},{"key":"10.1016\/j.jvir.2023.05.026_bib22","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1148\/rg.293085729","article-title":"Varying appearances of cholangiocarcinoma: radiologic-pathologic correlation","volume":"29","author":"Chung","year":"2009","journal-title":"Radiographics"},{"key":"10.1016\/j.jvir.2023.05.026_bib23","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.jvir.2013.10.056","volume":"25","author":"Camacho","year":"2014","journal-title":"J\u00a0Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2023.05.026_bib24","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1148\/radiol.12112142","article-title":"Intrahepatic cholangiocarcinoma treated with local-regional therapy: quantitative volumetric apparent diffusion coefficient maps for assessment of tumor response","volume":"264","author":"Halappa","year":"2012","journal-title":"Radiology"},{"key":"10.1016\/j.jvir.2023.05.026_bib25","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1016\/j.jvir.2013.02.031","article-title":"Yttrium-90 radioembolization for intrahepatic cholangiocarcinoma: safety, response, and survival analysis","volume":"24","author":"Mouli","year":"2013","journal-title":"J\u00a0Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2023.05.026_bib26","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1016\/j.jvir.2021.08.009","article-title":"Neoadjuvant yttrium-90 transarterial radioembolization with resin microspheres prescribed using the medical internal radiation dose model for intrahepatic cholangiocarcinoma","volume":"32","author":"Sarwar","year":"2021","journal-title":"J\u00a0Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2023.05.026_bib27","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/j.jvir.2022.12.017","article-title":"Yttrium-90 radioembolization and concomitant systemic gemcitabine, cisplatin, and capecitabine as the first-line therapy for locally advanced intrahepatic cholangiocarcinoma","volume":"34","author":"Ahmed","year":"2023","journal-title":"J\u00a0Vasc Interv Radiol"}],"container-title":["Journal of Vascular and Interventional Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1051044323003718?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1051044323003718?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T06:10:11Z","timestamp":1760940611000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1051044323003718"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":27,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["S1051044323003718"],"URL":"https:\/\/doi.org\/10.1016\/j.jvir.2023.05.026","relation":{},"ISSN":["1051-0443"],"issn-type":[{"value":"1051-0443","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Radioembolization with Yttrium-90 Glass Microspheres as a First-Line Treatment for Unresectable Intrahepatic Cholangiocarcinoma\u2014A Prospective Feasibility Study","name":"articletitle","label":"Article Title"},{"value":"Journal of Vascular and Interventional Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jvir.2023.05.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 SIR, 2023","name":"copyright","label":"Copyright"}]}}