{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:39:38Z","timestamp":1792726778524,"version":"4.5.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jvir.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Vascular and Interventional Radiology"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.jvir.2026.109022","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T15:36:07Z","timestamp":1786548967000},"page":"109022","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Imipenem\/Cilastatin Versus Imipenem\/Cilastatin Plus Ethiodized Oil in Genicular Artery Embolization: Safety and Clinical Success in a Comparative Cohort Study"],"prefix":"10.1016","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1484-4496","authenticated-orcid":false,"given":"Samet","family":"Genez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamza","family":"\u00d6zer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunus","family":"Y\u0131lmazsoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2183-7080","authenticated-orcid":false,"given":"Oya","family":"Kalayc\u0131o\u011flu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0281-1128","authenticated-orcid":false,"given":"\u00d6mer Faruk","family":"Ate\u015f","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Ta\u015f\u00e7\u0131","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jvir.2026.109022_bib1","doi-asserted-by":"crossref","first-page":"9332","DOI":"10.1073\/pnas.1703856114","article-title":"Knee osteoarthritis has doubled in prevalence since the mid-20th century","volume":"114","author":"Wallace","year":"2017","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jvir.2026.109022_bib2","article-title":"Global, regional prevalence, incidence and risk factors of knee osteoarthritis in population-based studies","volume":"29\u201330","author":"Cui","year":"2020","journal-title":"EClinicalMedicine"},{"key":"10.1016\/j.jvir.2026.109022_bib3","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1002\/art.41142","article-title":"2019 American college of rheumatology\/arthritis foundation guideline for the management of osteoarthritis of the hand, hip, and knee","volume":"72","author":"Kolasinski","year":"2020","journal-title":"Arthritis Rheumatol"},{"key":"10.1016\/j.jvir.2026.109022_bib4","doi-asserted-by":"crossref","first-page":"919.e1","DOI":"10.1016\/j.jvir.2021.03.409","article-title":"Percutaneous management of osteoarthritis in the knee: proceedings from the society of interventional radiology research consensus panel","volume":"32","author":"Ahmed","year":"2021","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2026.109022_bib5","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.joca.2014.01.003","article-title":"OARSI guidelines for the non-surgical management of knee osteoarthritis","volume":"22","author":"McAlindon","year":"2014","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.jvir.2026.109022_bib6","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1055\/s-0037-1604152","article-title":"Pain control in total knee arthroplasty","volume":"31","author":"Elmallah","year":"2018","journal-title":"J Knee Surg"},{"key":"10.1016\/j.jvir.2026.109022_bib7","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/j.diii.2021.05.012","article-title":"Minimally invasive loco-regional treatments for painful knee osteoarthritis: the time has come","volume":"102","author":"Spiliopoulos","year":"2021","journal-title":"Diagn Interv Imaging"},{"key":"10.1016\/j.jvir.2026.109022_bib8","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1007\/s00270-014-0944-8","article-title":"Transcatheter arterial embolization as a treatment for medial knee pain in patients with mild to moderate osteoarthritis","volume":"38","author":"Okuno","year":"2015","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.jvir.2026.109022_bib9","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.1016\/j.jvir.2023.08.029","article-title":"Genicular artery embolization for treatment of knee osteoarthritis: interim analysis of a prospective pilot trial including effect on serum osteoarthritis-associated biomarkers","volume":"34","author":"Taslakian","year":"2023","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2026.109022_bib10","article-title":"Pathophysiology of knee osteoarthritis and mechanisms of genicular artery embolization for interventional radiologists","volume":"37","author":"Sajan","year":"2025","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2026.109022_bib11","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/j.jvir.2017.02.033","article-title":"Midterm clinical outcomes and MR imaging changes after transcatheter arterial embolization as a treatment for mild to moderate radiographic knee osteoarthritis resistant to conservative treatment","volume":"28","author":"Okuno","year":"2017","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2026.109022_bib12","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1007\/s00270-025-04188-3","article-title":"Genicular artery embolization for symptomatic knee osteoarthritis: a comprehensive review of techniques and clinical outcomes","volume":"48","author":"Ahmed","year":"2025","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.jvir.2026.109022_bib13","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1016\/j.jvir.2024.04.018","article-title":"Society of interventional radiology research reporting standards for genicular artery embolization","volume":"35","author":"Ahmed","year":"2024","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2026.109022_bib14","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1007\/s00117-024-01388-9","article-title":"Knee pain improvement after genicular artery embolization for the management of knee osteoarthritis: an updated systematic review and meta-analysis of 21 studies","volume":"64","author":"Chlorogiannis","year":"2024","journal-title":"Radiologie (Heidelb)"},{"key":"10.1016\/j.jvir.2026.109022_bib15","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.1007\/s00270-024-03752-7","article-title":"Genicular artery embolisation in patients with osteoarthritis of the knee (GENESIS) using permanent microspheres: long-term results","volume":"47","author":"Little","year":"2024","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.jvir.2026.109022_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejrad.2024.111443","article-title":"Genicular artery embolization for the treatment of knee pain secondary to mild to severe knee osteoarthritis: one year clinical outcomes","volume":"175","author":"Sun","year":"2024","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.jvir.2026.109022_bib17","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1055\/s-0044-1788029","article-title":"Genicular artery embolization: embolic material and imaging review","volume":"41","author":"Rouzbahani","year":"2024","journal-title":"Semin Intervent Radiol"},{"key":"10.1016\/j.jvir.2026.109022_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.jvir.2026.108803","article-title":"Society of interventional radiology position statement on genicular artery embolization for symptomatic knee osteoarthritis","volume":"37","author":"Ahmed","year":"2026","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2026.109022_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00270-020-02687-z","article-title":"Genicular artery embolization for osteoarthritis related knee pain: a systematic review and qualitative analysis of clinical outcomes","volume":"44","author":"Casadaban","year":"2021","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.jvir.2026.109022_bib20","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1007\/s00270-025-04243-z","article-title":"Imipenem\/cilastatin in embolization: from antibiotic to therapeutic agent","volume":"48","author":"Rouzbahani","year":"2025","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.jvir.2026.109022_bib21","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.diii.2023.12.003","article-title":"Genicular artery embolization for knee osteoarthritis: results of the LipioJoint-1 trial","volume":"105","author":"Sapoval","year":"2024","journal-title":"Diagn Interv Imaging"},{"key":"10.1016\/j.jvir.2026.109022_bib22","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1136\/ard.16.4.494","article-title":"Radiological assessment of osteo-arthrosis","volume":"16","author":"Kellgren","year":"1957","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jvir.2026.109022_bib23","first-page":"1833","article-title":"Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee","volume":"15","author":"Bellamy","year":"1988","journal-title":"J Rheumatol"},{"key":"10.1016\/j.jvir.2026.109022_bib24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jvir.2022.10.011","article-title":"Adverse event classification: clarification and validation of the society of interventional radiology specialty\u2013specific system","volume":"34","author":"Baerlocher","year":"2023","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2026.109022_bib25","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1007\/s00270-022-03089-z","article-title":"GAUCHO\u2014trial genicular artery embolization using imipenem\/cilastatin vs. microsphere for knee osteoarthritis: a randomized controlled trial","volume":"45","author":"Correa","year":"2022","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.jvir.2026.109022_bib26","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.critrevonc.2013.07.003","article-title":"Use of Lipiodol as a drug-delivery system for transcatheter arterial chemoembolization of hepatocellular carcinoma: a review","volume":"88","author":"Id\u00e9e","year":"2013","journal-title":"Crit Rev Oncol Hematol"},{"key":"10.1016\/j.jvir.2026.109022_bib27","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1007\/s00270-024-03836-4","article-title":"Lipiodol versus imipenem\/cilastatin in genicular artery embolization: a retrospective study on safety and clinical success","volume":"47","author":"Guzelbey","year":"2024","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.jvir.2026.109022_bib28","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1007\/s00270-025-04134-3","article-title":"Letter to the editor: genicular artery embolization using a Lipiodol-based emulsion","volume":"48","author":"Sapoval","year":"2025","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.jvir.2026.109022_bib29","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1007\/s00270-023-03422-0","article-title":"Genicular artery embolization as a treatment for osteoarthritis related knee pain: a systematic review and meta-analysis","volume":"46","author":"Epelboym","year":"2023","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.jvir.2026.109022_bib30","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.jvir.2021.12.019","article-title":"Cadaveric classification of the genicular arteries, with implications for the interventional radiologist","volume":"33","author":"Sighary","year":"2022","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2026.109022_bib31","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.jvir.2023.12.010","article-title":"Genicular artery embolization: a review of essential anatomic considerations","volume":"35","author":"Liu","year":"2024","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2026.109022_bib32","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1016\/j.jvir.2024.08.028","article-title":"Genicular artery embolization for treatment of symptomatic knee osteoarthritis: 2-year outcomes from a prospective IDE trial","volume":"35","author":"Cusumano","year":"2024","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvir.2026.109022_bib33","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1007\/s00270-019-02289-4","article-title":"Clinical outcomes of transcatheter arterial embolisation for chronic knee pain: mild-to-moderate versus severe knee osteoarthritis","volume":"42","author":"Lee","year":"2019","journal-title":"Cardiovasc Intervent Radiol"}],"container-title":["Journal of Vascular and Interventional Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S105104432601033X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S105104432601033X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:18:18Z","timestamp":1792725498000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S105104432601033X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":33,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["S105104432601033X"],"URL":"https:\/\/doi.org\/10.1016\/j.jvir.2026.109022","relation":{},"ISSN":["1051-0443"],"issn-type":[{"value":"1051-0443","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Imipenem\/Cilastatin Versus Imipenem\/Cilastatin Plus Ethiodized Oil in Genicular Artery Embolization: Safety and Clinical Success in a Comparative Cohort Study","name":"articletitle","label":"Article Title"},{"value":"Journal of Vascular and Interventional Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jvir.2026.109022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 SIR, 2026","name":"copyright","label":"Copyright"}],"article-number":"109022"}}