{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T17:21:10Z","timestamp":1762017670213,"version":"3.44.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["22510091"],"award-info":[{"award-number":["22510091"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Virological Methods"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1016\/j.jviromet.2013.08.007","type":"journal-article","created":{"date-parts":[[2013,8,27]],"date-time":"2013-08-27T15:18:11Z","timestamp":1377616691000},"page":"154-160","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Application of electrolysis for inactivation of an antiviral drug that is one of possible selection pressure to drug-resistant influenza viruses"],"prefix":"10.1016","volume":"194","author":[{"given":"Toyohide","family":"Kobayashi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Hirose","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kouichi","family":"Sano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiro","family":"Katsumata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Tsujibo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Nakano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jviromet.2013.08.007_bib0005","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/j.chemosphere.2010.02.022","article-title":"Dissipation and removal of oseltamivir (Tamiflu) in different aquatic environments","volume":"79","author":"Accinelli","year":"2010","journal-title":"Chemosphere"},{"key":"10.1016\/j.jviromet.2013.08.007_bib0010","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.chemosphere.2010.06.074","article-title":"Removal of oseltamivir (Tamiflu) and other selected pharmaceuticals from wastewater using a granular bioplastic formulation entrapping propagules of phanerochaete chrysosporium","volume":"81","author":"Accinelli","year":"2010","journal-title":"Chemosphere"},{"key":"10.1016\/j.jviromet.2013.08.007_bib0015","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.scitotenv.2008.06.032","article-title":"The environmental fate of the antiviral drug oseltamivir carboxylate in different waters","volume":"405","author":"Bartels","year":"2008","journal-title":"Sci. Total Environ."},{"issue":"10","key":"10.1016\/j.jviromet.2013.08.007_bib0020","doi-asserted-by":"crossref","first-page":"e986","DOI":"10.1371\/journal.pone.0000986","article-title":"Antiviral oseltamivir is not removed or degraded in normal sewage water treatment: implications for development of resistance by influenza A virus","volume":"2","author":"Fick","year":"2007","journal-title":"PLoS ONE"},{"key":"10.1016\/j.jviromet.2013.08.007_bib0025","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1289\/ehp.0900930","article-title":"Oseltamivir carboxylate, the active metabolite of oseltamivir phosphate (Tamiflu), detected in sewage discharge and river water in Japan","volume":"118","author":"Ghosh","year":"2010","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.jviromet.2013.08.007_bib0030","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.chemosphere.2010.07.023","article-title":"Occurrence and fate of oseltamivir carboxylate (Tamiflu) and amantadine in sewage treatment plants","volume":"81","author":"Ghosh","year":"2010","journal-title":"Chemosphere"},{"key":"10.1016\/j.jviromet.2013.08.007_bib0035","doi-asserted-by":"crossref","first-page":"4307","DOI":"10.1021\/es1032629","article-title":"Photofate of oseltamivir (Tamiflu) and oseltamivir carboxylate under natural and simulated solar irradiation: kinetics, identification of the transformation products, and environmental occurrence","volume":"45","author":"Gon\u00e7alves","year":"2011","journal-title":"Environ. Sci. Technol."},{"issue":"10 Suppl.","key":"10.1016\/j.jviromet.2013.08.007_bib0040","first-page":"S58","article-title":"Antivirals in the management of an influenza pandemic","volume":"185","author":"Harrod","year":"2006","journal-title":"Med. J. Aust."},{"key":"10.1016\/j.jviromet.2013.08.007_bib0045","doi-asserted-by":"crossref","first-page":"471","DOI":"10.2165\/00003088-199937060-00003","article-title":"Clinical pharmacokinetics of the prodrug oseltamivir and its active metabolite Ro 64-0802","volume":"37","author":"He","year":"1999","journal-title":"Clin. Pharmacokinet."},{"key":"10.1016\/j.jviromet.2013.08.007_bib0050","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1124\/dmd.30.1.13","article-title":"The anti-influenza drug oseltamivir exhibits low potential to induce pharmacokinetic drug interactions via renal secretion-correlation of in vivo and in vitro studies","volume":"30","author":"Hill","year":"2002","journal-title":"Drug Metab. Dispos."},{"key":"10.1016\/j.jviromet.2013.08.007_bib0055","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1016\/j.chemosphere.2005.01.024","article-title":"Inactivation of antineoplastics in clinical wastewater by electrolysis","volume":"60","author":"Hirose","year":"2005","journal-title":"Chemosphere"},{"issue":"9","key":"10.1016\/j.jviromet.2013.08.007_bib0060","doi-asserted-by":"crossref","first-page":"e24742","DOI":"10.1371\/journal.pone.0024742","article-title":"Environmental levels of the antiviral oseltamivir induce development of resistance mutation H274Y in influenza A\/H1N1 virus in Mallards","volume":"6","author":"J\u00e4rhult","year":"2011","journal-title":"PLoS ONE"},{"key":"10.1016\/j.jviromet.2013.08.007_bib0065","first-page":"18385","article-title":"Oseltamivir (Tamiflu\u00ae) in the environment, resistance development in influenza A viruses of dabbling ducks and the risk of transmission of an oseltamivir-resistant virus to humans \u2013 a review","volume":"2","author":"J\u00e4rhult","year":"2012","journal-title":"Infect. Ecol. Epidemiol."},{"key":"10.1016\/j.jviromet.2013.08.007_bib0070","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1016\/j.jpba.2007.04.002","article-title":"Development and validation of a rapid HPLC method for the determination of oseltamivir phosphate in Tamiflu and genetic versions","volume":"44","author":"Joseph-Charles","year":"2007","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jviromet.2013.08.007_bib0075","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.chemosphere.2008.02.020","article-title":"Evaluation of electrolysis apparatus for inactivating antineoplastics in clinical wastewater","volume":"72","author":"Kobayashi","year":"2008","journal-title":"Chemosphere"},{"key":"10.1016\/j.jviromet.2013.08.007_bib0080","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.ecoenv.2011.11.028","article-title":"Application of electrolysis for detoxification of an antineoplastic in urine","volume":"78","author":"Kobayashi","year":"2012","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.jviromet.2013.08.007_bib0085","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1128\/AAC.42.3.647","article-title":"Identification of GS 4104 as an orally bioavailable prodrug of the influenza virus neuraminidase inhibitor GS 4071","volume":"42","author":"Li","year":"1998","journal-title":"Antimicrob. Agents Chemother."},{"year":"2008","series-title":"Water Environment Division, Environmental Management Bureau","author":"Manual on analysis of investigated items (water, soil, aquatic organism)","key":"10.1016\/j.jviromet.2013.08.007_bib0090"},{"key":"10.1016\/j.jviromet.2013.08.007_bib0100","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.ecoenv.2012.12.017","article-title":"Application of electrolysis inactivation to antibacterials in clinical use","volume":"90","author":"Nakano","year":"2013","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.jviromet.2013.08.007_bib0105","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0165-1161(85)90062-7","article-title":"Evaluation of the new system (Umu-test) for the detection of environmental mutagenicity and carcinogens","volume":"147","author":"Oda","year":"1985","journal-title":"Mutat. Res."},{"key":"10.1016\/j.jviromet.2013.08.007_bib0110","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1126\/science.1122438","article-title":"Global patterns of influenza a virus in wild birds","volume":"312","author":"Olsen","year":"2006","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.jviromet.2013.08.007_bib0115","doi-asserted-by":"crossref","first-page":"e16028","DOI":"10.1371\/journal.pone.0016028","article-title":"Detection of resistance mutations to Antivirals oseltamivir and zanamivir in avian influenza a viruses isolated from wild birds","volume":"6","author":"Orozovic","year":"2011","journal-title":"PLoS ONE"},{"key":"10.1016\/j.jviromet.2013.08.007_bib0120","doi-asserted-by":"crossref","first-page":"6541","DOI":"10.1021\/cr9001319","article-title":"Direct and mediated anodic oxidation of organic pollutants","volume":"109","author":"Panizza","year":"2009","journal-title":"Chem. Rev."},{"key":"10.1016\/j.jviromet.2013.08.007_bib0125","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.chemosphere.2008.11.060","article-title":"Environmental fate of the antiviral drug Tamiflu in two aquatic ecosystems","volume":"75","author":"Sacc\u00e0","year":"2009","journal-title":"Chemosphere"},{"key":"10.1016\/j.jviromet.2013.08.007_bib0130","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S1473-3099(06)70684-3","article-title":"WHO rapid advise guidelines for pharmacological management of sporadic human infection with avian influenza A (H5N1) virus","volume":"7","author":"Sch\u00fcnemann","year":"2007","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.jviromet.2013.08.007_bib0135","first-page":"2148","article-title":"Mutagenicity of several classes of antitumor agents to Salmonella Typhimurium TA98, TA100 and TA92","volume":"38","author":"Seino","year":"1978","journal-title":"Cancer Res."},{"key":"10.1016\/j.jviromet.2013.08.007_bib0140","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1289\/ehp.9574","article-title":"Potential risks associated with the proposed widespread use of Tamiflu","volume":"115","author":"Singer","year":"2007","journal-title":"Environ. Health Perspect."},{"issue":"6","key":"10.1016\/j.jviromet.2013.08.007_bib0145","doi-asserted-by":"crossref","first-page":"e6064","DOI":"10.1371\/journal.pone.0006064","article-title":"Detection of the antiviral drug oseltamivir in aquatic environments","volume":"4","author":"S\u00f6derstr\u00f6m","year":"2009","journal-title":"PLoS ONE"},{"key":"10.1016\/j.jviromet.2013.08.007_bib0150","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1016\/j.ecoenv.2008.09.011","article-title":"An environmental risk assessment for oseltamivir (Tamiflu) for sewage works and surface waters under seasonal-influenza- and pandemic-use conditions","volume":"72","author":"Straub","year":"2009","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.jviromet.2013.08.007_bib0155","unstructured":"Tamiflu interviewform, 2009. Chugai Pharmaceutical Co. Ltd. (in Japanese)."},{"key":"10.1016\/j.jviromet.2013.08.007_bib0160","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1038\/nrd2400","article-title":"The war against influenza: discovery and development of sialidase inhibitors","volume":"12","author":"von Itzstein","year":"2007","journal-title":"Nat. Rev. Drug Discov."},{"issue":"Suppl. 1","key":"10.1016\/j.jviromet.2013.08.007_bib0165","doi-asserted-by":"crossref","first-page":"i5","DOI":"10.1093\/jac\/dki018","article-title":"Oseltamivir (Tamiflu) and its potential for use in the event of an influenza pandemic","volume":"55","author":"Ward","year":"2005","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.jviromet.2013.08.007_bib0170","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1128\/JCM.41.2.742-750.2003","article-title":"Evaluation of neuraminidase enzyme assays using different substrates to measure susceptibility of influenza virus clinical isolates to neuraminidase inhibitors: report of the neuraminidase inhibitor susceptibility network","author":"Wetherall","year":"2003","journal-title":"J. Clin. Microbiol."},{"year":"2003","series-title":"Influenza (Seasonal). Fact Sheet No. 211","author":"WHO (World Health Organization)","key":"10.1016\/j.jviromet.2013.08.007_bib0175"}],"container-title":["Journal of Virological Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016609341300339X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016609341300339X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T10:49:17Z","timestamp":1759056557000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016609341300339X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":34,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["S016609341300339X"],"URL":"https:\/\/doi.org\/10.1016\/j.jviromet.2013.08.007","relation":{},"ISSN":["0166-0934"],"issn-type":[{"type":"print","value":"0166-0934"}],"subject":[],"published":{"date-parts":[[2013,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Application of electrolysis for inactivation of an antiviral drug that is one of possible selection pressure to drug-resistant influenza viruses","name":"articletitle","label":"Article Title"},{"value":"Journal of Virological Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jviromet.2013.08.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}