{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T00:18:13Z","timestamp":1783124293570,"version":"3.54.6"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004748","name":"Mashhad University of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004748","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Virological Methods"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.jviromet.2026.115404","type":"journal-article","created":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T06:28:39Z","timestamp":1778480919000},"page":"115404","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Preliminary screening reveals HPV-derived cDNA in the HNCF-PI 52 cell line originally derived from normal cervical tissue"],"prefix":"10.1016","volume":"344","author":[{"given":"Zahra","family":"Meshkat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Keramati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir Hossein","family":"Esfandiari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam Sadat","family":"Nabavinia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roghayeh","family":"Teimourpour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Reza","family":"Abbaszadegan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6399-1612","authenticated-orcid":false,"given":"Aida","family":"Gholoobi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jviromet.2026.115404_bib1","doi-asserted-by":"crossref","first-page":"93","DOI":"10.3389\/fonc.2019.00093","article-title":"Putative Role of Circulating Human Papillomavirus DNA in the Development of Primary Squamous Cell Carcinoma of the Middle Rectum: A Case Report","volume":"9","author":"Ambrosio","year":"2019","journal-title":"Front Oncol."},{"issue":"1","key":"10.1016\/j.jviromet.2026.115404_bib2","first-page":"266","article-title":"In-vitro Pro Apoptotic Effect of Crude Saponin from Ophiocoma erinaceus against Cervical Cancer","volume":"16","author":"Amini","year":"2017","journal-title":"Iran. J. Pharm. Res"},{"issue":"1","key":"10.1016\/j.jviromet.2026.115404_bib3","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1186\/s12967-025-06470-x","article-title":"Human papilloma virus (HPV) mediated cancers: an insightful update","volume":"23","author":"Baba","year":"2025","journal-title":"J. Transl. Med"},{"issue":"4","key":"10.1016\/j.jviromet.2026.115404_bib4","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1128\/jvi.61.4.962-971.1987","article-title":"Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines","volume":"61","author":"Baker","year":"1987","journal-title":"J. Virol."},{"issue":"3","key":"10.1016\/j.jviromet.2026.115404_bib5","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1128\/jcm.33.3.690-695.1995","article-title":"Nested PCR approach for detection and typing of epidermodysplasia verruciformis-associated human papillomavirus types in cutaneous cancers from renal transplant recipients","volume":"33","author":"Berkhout","year":"1995","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.jviromet.2026.115404_bib6","unstructured":"Cellosaurus. HNCF-PI-52. 2024 [cited 13 July 2024 13 July 2024]; Available from: \u3008https:\/\/www.cellosaurus.org\/CVCL_9V83\u3009."},{"issue":"5","key":"10.1016\/j.jviromet.2026.115404_bib7","doi-asserted-by":"crossref","first-page":"741","DOI":"10.2144\/000112016","article-title":"Infectious pathogen detection arrays: viral detection in cell lines and postmortem brain tissue","volume":"39","author":"Conejero-Goldberg","year":"2005","journal-title":"BioTechniques"},{"issue":"5","key":"10.1016\/j.jviromet.2026.115404_bib8","doi-asserted-by":"crossref","DOI":"10.1099\/jmm.0.001833","article-title":"Dengue: A review of laboratory diagnostics in the vaccine age","volume":"73","author":"Frazer","year":"2024","journal-title":"J. Med. Microbiol."},{"issue":"2","key":"10.1016\/j.jviromet.2026.115404_bib9","doi-asserted-by":"crossref","DOI":"10.5812\/jjm.8939","article-title":"Comparison of culture and PCR methods for diagnosis of Mycobacterium tuberculosis in different clinical specimens","volume":"7","author":"Gholoobi","year":"2014","journal-title":"Jundishapur J. Microbiol."},{"key":"10.1016\/j.jviromet.2026.115404_bib10","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/j.molstruc.2017.04.024","article-title":"Biopolymer-mediated synthesis of Fe3O4 nanoparticles and investigation of their in vitro cytotoxicity effects","volume":"1141","author":"Gholoobi","year":"2017","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.jviromet.2026.115404_bib11","series-title":"Aptamers for targeting hpv16-positive tumor cells","author":"Gholoobi","year":"2022"},{"issue":"15","key":"10.1016\/j.jviromet.2026.115404_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e35063","article-title":"Extracellular vesicles and macrophages in tumor microenvironment: Impact on cervical cancer","volume":"10","author":"Guo","year":"2024","journal-title":"Heliyon"},{"key":"10.1016\/j.jviromet.2026.115404_bib13","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.mrrev.2016.07.002","article-title":"Human papillomavirus molecular biology","volume":"772","author":"Harden","year":"2017","journal-title":"Mutat. Res Rev. Mutat. Res"},{"key":"10.1016\/j.jviromet.2026.115404_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.virol.2025.110445","article-title":"Human viruses: An ever-increasing list","volume":"604","author":"He","year":"2025","journal-title":"Virology"},{"key":"10.1016\/j.jviromet.2026.115404_bib15","unstructured":"Iran, P.Io. General Cell Collection. (n.d.)[cited 2019 2\/12\/2019]; Available from: \u3008http:\/\/fa.pasteur.ac.ir\/visitLink.aspx?id=C491\u3009."},{"issue":"sup2","key":"10.1016\/j.jviromet.2026.115404_bib16","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1080\/21691401.2018.1468770","article-title":"The combinational effect of E6\/E7 siRNA and anti-miR-182 on apoptosis induction in HPV16-positive cervical cells","volume":"46","author":"Javadi","year":"2018","journal-title":"Artif. Cells Nanomed. Biotechnol."},{"issue":"1","key":"10.1016\/j.jviromet.2026.115404_bib17","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.ejogrb.2011.06.021","article-title":"Prevalence and risk factors for human papillomavirus DNA in cervical cytology","volume":"159","author":"Kasap","year":"2011","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"issue":"10","key":"10.1016\/j.jviromet.2026.115404_bib18","first-page":"13777","article-title":"Relationship between hWAPL polymorphisms and cervical cancer susceptibility","volume":"8","author":"Li","year":"2015","journal-title":"Int. J. Clin. Exp. Pathol."},{"issue":"1","key":"10.1016\/j.jviromet.2026.115404_bib19","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1080\/17458080.2021.2013470","article-title":"Pectin mediated green synthesis of CuO nanoparticles: evaluation of its cytotoxicity, antioxidant and anti-human cervical cancer properties","volume":"17","author":"Liang","year":"2022","journal-title":"J. Exp. Nanosci."},{"issue":"4","key":"10.1016\/j.jviromet.2026.115404_bib20","doi-asserted-by":"crossref","first-page":"326","DOI":"10.4103\/0019-5154.113949","article-title":"No Evidence of Human Papillomaviruses in Non-genital Seborrheic Keratosis","volume":"58","author":"Meibodi","year":"2013","journal-title":"Indian J. Dermatol."},{"issue":"3","key":"10.1016\/j.jviromet.2026.115404_bib21","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1159\/000018489","article-title":"Frequency and spectrum of HPV types detected in cutaneous squamous-cell carcinomas depend on the HPV detection system: a comparison of four PCR assays","volume":"201","author":"Meyer","year":"2000","journal-title":"Dermatology"},{"issue":"7","key":"10.1016\/j.jviromet.2026.115404_bib22","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1099\/jmm.0.057521-0","article-title":"Normal and tumour cervical cells respond differently to vaginal lactobacilli, independent of pH and lactate","volume":"62","author":"Motevaseli","year":"2013","journal-title":"J. Med. Microbiol."},{"issue":"3","key":"10.1016\/j.jviromet.2026.115404_bib23","doi-asserted-by":"crossref","first-page":"199","DOI":"10.5812\/ircmj.3533","article-title":"Differences in vaginal lactobacilli composition of Iranian healthy and bacterial vaginosis infected women: a comparative analysis of their cytotoxic effects with commercial vaginal probiotics","volume":"15","author":"Motevaseli","year":"2013","journal-title":"Iran. Red. Crescent Med J."},{"issue":"5","key":"10.1016\/j.jviromet.2026.115404_bib24","doi-asserted-by":"crossref","first-page":"464","DOI":"10.3390\/pathogens14050464","article-title":"The Epithelial Immune Response to Human Papillomavirus Infection","volume":"14","author":"Roy-Biswas","year":"2025","journal-title":"Pathogens"},{"issue":"4","key":"10.1016\/j.jviromet.2026.115404_bib25","doi-asserted-by":"crossref","first-page":"426","DOI":"10.61186\/phypha.27.4.426","article-title":"Investigating the effects of Lactobacillus acidophilus and Lactobacillus paracasei supernatant on cervical cancer cells","volume":"27","author":"Samiei Mosleh","year":"2023","journal-title":"Physiol. Pharmacol."},{"issue":"5","key":"10.1016\/j.jviromet.2026.115404_bib26","doi-asserted-by":"crossref","DOI":"10.1098\/rsos.172472","article-title":"Screening for 15 pathogenic viruses in human cell lines registered at the JCRB Cell Bank: characterization of in vitro human cells by viral infection","volume":"5","author":"Shioda","year":"2018","journal-title":"R. Soc. Open Sci."},{"issue":"5","key":"10.1016\/j.jviromet.2026.115404_bib27","doi-asserted-by":"crossref","DOI":"10.1098\/rsos.172472","article-title":"Screening for 15 pathogenic viruses in human cell lines registered at the JCRB Cell Bank: characterization of in vitro human cells by viral infection","volume":"5","author":"Shioda","year":"2018","journal-title":"R. Soc. Open Sci."},{"issue":"2","key":"10.1016\/j.jviromet.2026.115404_bib28","doi-asserted-by":"crossref","first-page":"199","DOI":"10.32604\/biocell.2025.059322","article-title":"Assessing the Relationship between Lactobacilli and HPV: A Decade of Research","volume":"49","author":"Triggiano","year":"2025","journal-title":"Biocell"},{"key":"10.1016\/j.jviromet.2026.115404_bib29","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.ejogrb.2024.07.036","article-title":"Prognostic value of human papillomavirus cell-free DNA in cervical cancer patients: A systematic review and meta-analysis","volume":"300","author":"Wang","year":"2024","journal-title":"Eur. J. Obstet. & Gynecol. Reprod. Biol."},{"issue":"3","key":"10.1016\/j.jviromet.2026.115404_bib30","doi-asserted-by":"crossref","DOI":"10.1002\/rmv.2537","article-title":"Human papillomavirus infection: Epidemiology, biology, host interactions, cancer development, prevention, and therapeutics","volume":"34","author":"Wolf","year":"2024","journal-title":"Rev. Med. Virol."},{"key":"10.1016\/j.jviromet.2026.115404_bib31","article-title":"Unveiling the multifaceted realm of human papillomavirus: a comprehensive exploration of biology, interactions, and advances in cancer management","volume":"15","author":"Wu","year":"2024","journal-title":"Front. Immunol."},{"issue":"3","key":"10.1016\/j.jviromet.2026.115404_bib32","first-page":"361","article-title":"Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines","volume":"119","author":"Yee","year":"1985","journal-title":"Am. J. Pathol."},{"issue":"6","key":"10.1016\/j.jviromet.2026.115404_bib33","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19061706","article-title":"High-Risk Human Papillomaviral Oncogenes E6 and E7 Target Key Cellular Pathways to Achieve Oncogenesis","volume":"19","author":"Yeo-Teh","year":"2018","journal-title":"Int J. Mol. Sci."},{"issue":"5","key":"10.1016\/j.jviromet.2026.115404_bib34","doi-asserted-by":"crossref","DOI":"10.1128\/mbio.00729-24","article-title":"HPV oncogenes expressed from only one of multiple integrated HPV DNA copies drive clonal cell expansion in cervical cancer","volume":"15","author":"Yu","year":"2024","journal-title":"mBio"}],"container-title":["Journal of Virological Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166093426000698?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166093426000698?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T23:31:33Z","timestamp":1783121493000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166093426000698"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":34,"alternative-id":["S0166093426000698"],"URL":"https:\/\/doi.org\/10.1016\/j.jviromet.2026.115404","relation":{},"ISSN":["0166-0934"],"issn-type":[{"value":"0166-0934","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Preliminary screening reveals HPV-derived cDNA in the HNCF-PI 52 cell line originally derived from normal cervical tissue","name":"articletitle","label":"Article Title"},{"value":"Journal of Virological Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jviromet.2026.115404","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"115404"}}