{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T14:51:21Z","timestamp":1782139881412,"version":"3.54.5"},"reference-count":28,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003593","name":"National Council for Scientific and Technological Development","doi-asserted-by":"publisher","award":["409707\/2016-3"],"award-info":[{"award-number":["409707\/2016-3"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Vascular Nursing"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.jvn.2025.09.002","type":"journal-article","created":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T23:17:17Z","timestamp":1759792637000},"page":"1-5","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Light physical activity and sedentary time are associated with multiple comorbid conditions in patients with peripheral artery disease"],"prefix":"10.1016","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8559-7752","authenticated-orcid":false,"given":"Alu\u00edsio","family":"Andrade-Lima","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2286-5892","authenticated-orcid":false,"given":"Breno Quintella","family":"Farah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0327-4739","authenticated-orcid":false,"given":"Antonio Henrique","family":"Germano-Soares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0406-6504","authenticated-orcid":false,"given":"H\u00e9lcio","family":"Kanegusuku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelson","family":"Wolosker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8983-3433","authenticated-orcid":false,"given":"Marilia de Almeida","family":"Correia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7883-6746","authenticated-orcid":false,"given":"Raphael Mendes","family":"Ritti-Dias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.jvn.2025.09.002_bib0001","doi-asserted-by":"crossref","first-page":"e721","DOI":"10.1016\/S2214-109X(20)30117-0","article-title":"Global and regional prevalence, burden, and risk factors for carotid atherosclerosis: a systematic review, meta-analysis, and modelling study","volume":"8","author":"Song","year":"2020","journal-title":"Lancet Glob Health"},{"issue":"9901","key":"10.1016\/j.jvn.2025.09.002_bib0002","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/S0140-6736(13)61249-0","article-title":"Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysis","volume":"382","author":"Fowkes","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.jvn.2025.09.002_bib0003","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.atherosclerosis.2019.09.012","article-title":"Morbidity and mortality associated with atherosclerotic peripheral artery disease: a systematic review","volume":"293","author":"Agnelli","year":"2020","journal-title":"Atherosclerosis"},{"issue":"4","key":"10.1016\/j.jvn.2025.09.002_bib0004","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1016\/j.jvs.2020.09.039","article-title":"A systematic review and meta-analysis of gender differences in long-term mortality and cardiovascular events in peripheral artery disease","volume":"73","author":"Parvar","year":"2021","journal-title":"J Vasc Surg"},{"issue":"3","key":"10.1016\/j.jvn.2025.09.002_bib0005","first-page":"410","article-title":"Physical Activity Levels in Peripheral Artery Disease Patients","volume":"113","author":"Gerage","year":"2019","journal-title":"Arq Bras Cardiol"},{"issue":"1","key":"10.1016\/j.jvn.2025.09.002_bib0006","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jvs.2007.09.033","article-title":"Physical activity is a predictor of all-cause mortality in patients with intermittent claudication","volume":"47","author":"Gardner","year":"2008","journal-title":"J Vasc Surg"},{"issue":"3","key":"10.1016\/j.jvn.2025.09.002_bib0007","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1161\/CIRCULATIONAHA.105.605246","article-title":"Physical activity during daily life and mortality in patients with peripheral arterial disease","volume":"114","author":"Garg","year":"2006","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.jvn.2025.09.002_bib0008","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1177\/1358863X15626521","article-title":"Community walking speed, sedentary or lying down time, and mortality in peripheral artery disease","volume":"21","author":"McDermott","year":"2016","journal-title":"Vasc Med"},{"issue":"4","key":"10.1016\/j.jvn.2025.09.002_bib0009","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1249\/MSS.0000000000002526","article-title":"Association between physical activity and mortality in patients with claudication","volume":"53","author":"Gardner","year":"2021","journal-title":"Med Sci Sports Exerc"},{"issue":"5","key":"10.1016\/j.jvn.2025.09.002_bib0010","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1016\/j.jvs.2021.12.071","article-title":"Light and moderate intensity physical activity are associated with better ambulation, quality of life, and vascular measurements in patients with claudication","volume":"75","author":"Gardner","year":"2022","journal-title":"J Vasc Surg"},{"issue":"4","key":"10.1016\/j.jvn.2025.09.002_bib0011","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1123\/jpah.2020-0487","article-title":"Reallocating time from sedentary behavior to physical activity in patients with peripheral artery disease: analyzing the effects on walking capacity using compositional data analysis","volume":"18","author":"Germano-Soares","year":"2021","journal-title":"J Phys Act Health"},{"issue":"6","key":"10.1016\/j.jvn.2025.09.002_bib0012","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/j.ejvs.2016.07.082","article-title":"Factors associated with sedentary behavior in patients with intermittent claudication","volume":"52","author":"Farah","year":"2016","journal-title":"Eur J Vasc Endovasc Surg"},{"issue":"3","key":"10.1016\/j.jvn.2025.09.002_bib0013","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1007\/s12529-021-10014-0","article-title":"Impact and determinants of structural barriers on physical activity in people with cancer","volume":"29","author":"Depenbusch","year":"2022","journal-title":"Int J Behav Med"},{"issue":"4","key":"10.1016\/j.jvn.2025.09.002_bib0014","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1161\/01.ATV.0000158311.24443.af","article-title":"Physical inactivity increases oxidative stress, endothelial dysfunction, and atherosclerosis","volume":"25","author":"Laufs","year":"2005","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"3","key":"10.1016\/j.jvn.2025.09.002_bib0015","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.jvs.2015.09.018","article-title":"Sedentary behavior is associated with impaired biomarkers in claudicants","volume":"63","author":"Farah","year":"2016","journal-title":"J Vasc Surg"},{"issue":"1","key":"10.1016\/j.jvn.2025.09.002_bib0016","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1123\/jpah.2019-0377","article-title":"Sedentary behavior and chronic disease: mechanisms and future directions","volume":"17","author":"Dempsey","year":"2020","journal-title":"J Phys Act Health"},{"issue":"4","key":"10.1016\/j.jvn.2025.09.002_bib0017","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1152\/physrev.00019.2016","article-title":"Role of inactivity in chronic diseases: evolutionary insight and pathophysiological mechanisms","volume":"97","author":"Booth","year":"2017","journal-title":"Physiol Rev"},{"key":"10.1016\/j.jvn.2025.09.002_bib0018","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.atherosclerosis.2018.01.009","article-title":"Association of time spent in physical activities and sedentary behaviors with carotid-femoral pulse wave velocity: a systematic review and meta-analysis","volume":"269","author":"Germano-Soares","year":"2018","journal-title":"Atherosclerosis"},{"issue":"10","key":"10.1016\/j.jvn.2025.09.002_bib0019","doi-asserted-by":"crossref","first-page":"e297","DOI":"10.1371\/journal.pmed.0040297","article-title":"Strengthening the reporting of observational studies in epidemiology (STROBE): explanation and elaboration","volume":"4","author":"Vandenbroucke","year":"2007","journal-title":"PLoS Med"},{"issue":"24","key":"10.1016\/j.jvn.2025.09.002_bib0020","doi-asserted-by":"crossref","first-page":"2890","DOI":"10.1161\/CIR.0b013e318276fbcb","article-title":"Measurement and interpretation of the ankle-brachial index: a scientific statement from the American Heart Association","volume":"126","author":"Aboyans","year":"2012","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.jvn.2025.09.002_bib0021","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/j.jvs.2008.06.050","article-title":"Corridor-based functional performance measures correlate better with physical activity during daily life than treadmill measures in persons with peripheral arterial disease","volume":"48","author":"McDermott","year":"2008","journal-title":"J Vasc Surg"},{"issue":"2","key":"10.1016\/j.jvn.2025.09.002_bib0022","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1249\/MSS.0b013e3181ed61a3","article-title":"Validation of accelerometer wear and nonwear time classification algorithm","volume":"43","author":"Choi","year":"2011","journal-title":"Med Sci Sports Exerc"},{"issue":"1","key":"10.1016\/j.jvn.2025.09.002_bib0023","first-page":"17","article-title":"Accelerometer assessment of physical activity in active, healthy older adults","volume":"17","author":"Copeland","year":"2009","journal-title":"J Aging Phys Act"},{"issue":"23","key":"10.1016\/j.jvn.2025.09.002_bib0024","doi-asserted-by":"crossref","first-page":"2356","DOI":"10.1016\/j.jacc.2010.12.038","article-title":"Greater sedentary hours and slower walking speed outside the home predict faster declines in functioning and adverse calf muscle changes in peripheral arterial disease","volume":"57","author":"McDermott","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jvn.2025.09.002_bib0025","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.physbeh.2015.08.016","article-title":"Sedentary behavior and medical multimorbidity","volume":"151","author":"Loprinzi","year":"2015","journal-title":"Physiol Behav"},{"key":"10.1016\/j.jvn.2025.09.002_bib0026","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.maturitas.2020.01.007","article-title":"Physical multimorbidity and sedentary behavior in older adults: findings from the Irish longitudinal study on ageing (TILDA)","volume":"134","author":"Kandola","year":"2020","journal-title":"Maturitas"},{"issue":"1","key":"10.1016\/j.jvn.2025.09.002_bib0027","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1007\/s12529-014-9408-4","article-title":"Barriers to physical activity in patients with intermittent claudication","volume":"22","author":"Barbosa","year":"2015","journal-title":"Int J Behav Med"},{"issue":"4","key":"10.1016\/j.jvn.2025.09.002_bib0028","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1177\/0890117118796459","article-title":"Light-intensity physical activity and cardiometabolic risk among older adults with multiple chronic conditions","volume":"33","author":"Li","year":"2019","journal-title":"Am J Health Promot"}],"container-title":["Journal of Vascular Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1062030325001049?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1062030325001049?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T14:45:48Z","timestamp":1782139548000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1062030325001049"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["S1062030325001049"],"URL":"https:\/\/doi.org\/10.1016\/j.jvn.2025.09.002","relation":{},"ISSN":["1062-0303"],"issn-type":[{"value":"1062-0303","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Light physical activity and sedentary time are associated with multiple comorbid conditions in patients with peripheral artery disease","name":"articletitle","label":"Article Title"},{"value":"Journal of Vascular Nursing","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jvn.2025.09.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Society for Vascular Nursing, Inc. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}