{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T16:13:25Z","timestamp":1785860005959,"version":"3.56.0"},"reference-count":12,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jvoice.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Voice"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.jvoice.2025.04.004","type":"journal-article","created":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T15:47:20Z","timestamp":1745596040000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Buffered Lidocaine for Topical Nasal Anesthesia: A Double-Blind Randomized Controlled Trial"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4209-8846","authenticated-orcid":false,"given":"Kfir","family":"Siag","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9188-2480","authenticated-orcid":false,"given":"Miki","family":"Paker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2740-9792","authenticated-orcid":false,"given":"Yoni Evgeni","family":"Gutkovich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4555-8396","authenticated-orcid":false,"given":"Salim","family":"Mazzawi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jvoice.2025.04.004_bib1","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1002\/lary.23966","article-title":"A prospective, randomized, double-blind study comparing the efficacy of topical anesthetics in nasal endoscopy","volume":"123","author":"Gaviola","year":"2013","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jvoice.2025.04.004_bib2","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/0885-3924(94)00124-4","article-title":"Buffered lidocaine for skin infiltration prior to hemodialysis","volume":"10","author":"Richtsmeier","year":"1995","journal-title":"J Pain Symptom Manage"},{"key":"10.1016\/j.jvoice.2025.04.004_bib3","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0378-5173(99)00442-1","article-title":"Determination of baseline human nasal pH and the effect of intranasally administered buffers","volume":"198","author":"Washington","year":"2000","journal-title":"Int J Pharm"},{"key":"10.1016\/j.jvoice.2025.04.004_bib4","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.amjoto.2013.04.015","article-title":"Nasal pH in patients with chronic rhinosinusitis before and after endoscopic sinus surgery","volume":"34","author":"Kim","year":"2013","journal-title":"Am J Otolaryngol"},{"key":"10.1016\/j.jvoice.2025.04.004_bib5","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1046\/j.1365-2273.1999.00223.x","article-title":"Nasal pH measurement: a reliable and repeatable parameter","volume":"24","author":"England","year":"1999","journal-title":"Clin Otolaryngol All Sci"},{"key":"10.1016\/j.jvoice.2025.04.004_bib6","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/j.jhsa.2013.02.016","article-title":"The effect of buffered lidocaine in local anesthesia: a prospective, randomized, double-blind study","volume":"38","author":"Lee","year":"2013","journal-title":"J Hand Surg Am"},{"key":"10.1016\/j.jvoice.2025.04.004_bib7","first-page":"CD006581","article-title":"Adjusting the pH of lidocaine for reducing pain on injection","author":"Cepeda","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jvoice.2025.04.004_bib8","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1007\/s10006-018-0730-x","article-title":"\u201cSodium bicarbonate\u201d: an adjunct to painless palatal anesthesia","volume":"22","author":"Gupta","year":"2018","journal-title":"Oral Maxillofac Surg"},{"key":"10.1016\/j.jvoice.2025.04.004_bib9","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.adaj.2018.11.007","article-title":"Do buffered local anesthetics provide more successful anesthesia than nonbuffered solutions in patients with pulpally involved teeth requiring dental therapy? A systematic review","volume":"150","author":"Kattan","year":"2019","journal-title":"J Am Dent Assoc"},{"key":"10.1016\/j.jvoice.2025.04.004_bib10","first-page":"e1","article-title":"Novel direct injection chairside buffering technique for local anesthetic use in dentistry","volume":"40","author":"Goodchild","year":"2019","journal-title":"Compend Contin Educ Dent"},{"key":"10.1016\/j.jvoice.2025.04.004_bib11","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1111\/j.1365-2273.2004.00894.x","article-title":"\u201cMoffett\u2019s\u201d solution: a review of the evidence and scientific basis for the topical preparation of the nose","volume":"29","author":"Benjamin","year":"2004","journal-title":"Clin Otolaryngol Allied Sci"},{"key":"10.1016\/j.jvoice.2025.04.004_bib12","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1097\/00000542-194709000-00031","article-title":"Nasal analgesia by postural instillation","volume":"8","author":"Moffett","year":"1947","journal-title":"Anesthesiology"}],"container-title":["Journal of Voice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0892199725001535?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0892199725001535?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T12:50:26Z","timestamp":1777553426000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0892199725001535"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":12,"alternative-id":["S0892199725001535"],"URL":"https:\/\/doi.org\/10.1016\/j.jvoice.2025.04.004","relation":{},"ISSN":["0892-1997"],"issn-type":[{"value":"0892-1997","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Buffered Lidocaine for Topical Nasal Anesthesia: A Double-Blind Randomized Controlled Trial","name":"articletitle","label":"Article Title"},{"value":"Journal of Voice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jvoice.2025.04.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Voice Foundation. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}