{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:15:37Z","timestamp":1773011737973,"version":"3.50.1"},"reference-count":33,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,2,1]],"date-time":"2014-02-01T00:00:00Z","timestamp":1391212800000},"content-version":"vor","delay-in-days":731,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Vascular Surgery"],"published-print":{"date-parts":[[2012,2]]},"DOI":"10.1016\/j.jvs.2011.07.081","type":"journal-article","created":{"date-parts":[[2011,11,3]],"date-time":"2011-11-03T06:15:01Z","timestamp":1320300901000},"page":"489-496","source":"Crossref","is-referenced-by-count":32,"title":["Hypercholesterolemia and oxidative stress inhibit endothelial cell healing after arterial injury"],"prefix":"10.1016","volume":"55","author":[{"given":"Michael A.","family":"Rosenbaum","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiko","family":"Miyazaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda M.","family":"Graham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jvs.2011.07.081_bib1","first-page":"285","article-title":"Restenosis: relationship with thrombosis","volume":"2","author":"Sdringola","year":"2000","journal-title":"Curr Interv Cardiol Rep"},{"key":"10.1016\/j.jvs.2011.07.081_bib2","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1161\/01.ATV.12.10.1198","article-title":"Contribution of the endothelium to intimal thickening in normocholesterolemic and hypercholesterolemic rabbits","volume":"12","author":"Kisanuki","year":"1992","journal-title":"Arterioscler Thromb"},{"key":"10.1016\/j.jvs.2011.07.081_bib3","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S0008-6363(02)00409-1","article-title":"Hypercholesterolemia impairs vascular remodelling after porcine coronary angioplasty","volume":"55","author":"Theilmeier","year":"2002","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.jvs.2011.07.081_bib4","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0014-5793(90)80857-F","article-title":"Oxidized low-density lipoprotein is chemotactic for arterial smooth muscle cells in culture","volume":"277","author":"Autio","year":"1990","journal-title":"FEBS Lett"},{"key":"10.1016\/j.jvs.2011.07.081_bib5","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/BF00229586","article-title":"Role of oxidized human plasma low density lipoproteins in atherosclerosis: effects on smooth muscle cell proliferation","volume":"111","author":"Chatterjee","year":"1992","journal-title":"Mol Cell Biochem"},{"key":"10.1016\/j.jvs.2011.07.081_bib6","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1083\/jcb.120.4.1011","article-title":"Oxidized low density lipoprotein inhibits the migration of aortic endothelial cells in vitro","volume":"120","author":"Murugesan","year":"1993","journal-title":"J Cell Biol"},{"key":"10.1016\/j.jvs.2011.07.081_bib7","doi-asserted-by":"crossref","first-page":"2736","DOI":"10.1172\/JCI118728","article-title":"Role of lysophosphatidylcholine in the inhibition of endothelial cell motility by oxidized low density lipoprotein","volume":"97","author":"Murugesan","year":"1996","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jvs.2011.07.081_bib8","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1016\/j.jvs.2004.09.020","article-title":"Role of reactive oxygen species in inhibition of endothelial cell migration by oxidized low-density lipoprotein","volume":"40","author":"van Aalst","year":"2004","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.jvs.2011.07.081_bib9","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0300-483X(02)00382-7","article-title":"Role of antioxidants in paraquat toxicity","volume":"180","author":"Suntres","year":"2002","journal-title":"Toxicology"},{"key":"10.1016\/j.jvs.2011.07.081_bib10","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/0891-5849(89)90066-X","article-title":"The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid","volume":"6","author":"Aruoma","year":"1989","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.jvs.2011.07.081_bib11","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1046\/j.1523-1755.2003.00044.x","article-title":"AOPP-induced activation of human neutrophil and monocyte oxidative metabolism: a potential target for N-acetylcysteine treatment in dialysis patients","volume":"64","author":"Witko-Sarsat","year":"2003","journal-title":"Kidney Int"},{"key":"10.1016\/j.jvs.2011.07.081_bib12","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1161\/01.CIR.103.3.423","article-title":"Estradiol accelerates reendothelialization in mouse carotid artery through estrogen receptor-alpha but not estrogen receptor-beta","volume":"103","author":"Brouchet","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.jvs.2011.07.081_bib13","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1172\/JCI7811","article-title":"Decreased neointimal formation in Mac-1(\u2212\/\u2212) mice reveals a role for inflammation in vascular repair after angioplasty","volume":"105","author":"Simon","year":"2000","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jvs.2011.07.081_bib14","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1161\/01.RES.73.5.792","article-title":"Mouse model of arterial injury","volume":"73","author":"Lindner","year":"1993","journal-title":"Circ Res"},{"key":"10.1016\/j.jvs.2011.07.081_bib15","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/0006-2944(76)90049-1","article-title":"A simple fluorometric assay for lipoperoxide in blood plasma","volume":"15","author":"Yagi","year":"1976","journal-title":"Biochem Med"},{"key":"10.1016\/j.jvs.2011.07.081_bib16","doi-asserted-by":"crossref","first-page":"2520","DOI":"10.1172\/JCI117953","article-title":"Dietary Probucol preserves endothelial function in cholesterol-fed rabbits by limiting vascular oxidative stress and superoxide generation","volume":"95","author":"Keaney","year":"1995","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jvs.2011.07.081_bib17","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1161\/ATVBAHA.109.196592","article-title":"Increased PAFAH and oxidized lipids are associated with inflammation and atherosclerosis in hypercholesterolemic pigs","volume":"29","author":"De Keyzer","year":"2009","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jvs.2011.07.081_bib18","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1161\/01.CIR.0000062682.40051.43","article-title":"Probucol promotes functional reendothelialization in balloon-injured rabbit aortas","volume":"107","author":"Lau","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.jvs.2011.07.081_bib19","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1161\/CIRCULATIONAHA.105.553917","article-title":"Notch signaling regulates endothelial progenitor cell activity during recovery from arterial injury in hypercholesterolemic mice","volume":"121","author":"Ii","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.jvs.2011.07.081_bib20","doi-asserted-by":"crossref","first-page":"3801","DOI":"10.1074\/jbc.R100057200","article-title":"Control of cholesterol turnover in the mouse","volume":"277","author":"Dietschy","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jvs.2011.07.081_bib21","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1161\/01.ATV.21.5.739","article-title":"Increased NAD(P)H oxidase and reactive oxygen species in coronary arteries after balloon injury","volume":"21","author":"Shi","year":"2001","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jvs.2011.07.081_bib22","doi-asserted-by":"crossref","first-page":"3593","DOI":"10.1161\/01.CIR.96.10.3593","article-title":"Vitamins C and E inhibit O2- production in the pig coronary artery","volume":"96","author":"Nunes","year":"1997","journal-title":"Circulation"},{"key":"10.1016\/j.jvs.2011.07.081_bib23","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1161\/01.RES.86.5.549","article-title":"Redox changes of cultured endothelial cells and actin dynamics","volume":"86","author":"Moldovan","year":"2000","journal-title":"Circ Res"},{"key":"10.1016\/j.jvs.2011.07.081_bib24","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1006\/bbrc.1995.2508","article-title":"N-acetylcysteine diminishes injury induced by balloon angioplasty of the carotid artery in rabbits","volume":"215","author":"Mass","year":"1995","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.jvs.2011.07.081_bib25","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1055\/s-0037-1615659","article-title":"N-acetyl-cysteine reduces neointimal thickening and procoagulant activity after balloon-induced injury in abdominal aortae of New Zealand White rabbits","volume":"85","author":"Ghigliotti","year":"2001","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jvs.2011.07.081_bib26","doi-asserted-by":"crossref","first-page":"1999","DOI":"10.1161\/01.CIR.0000031331.05368.9D","article-title":"Adenovirus-mediated extracellular superoxide dismutase gene therapy reduces neointima formation in balloon-denuded rabbit aorta","volume":"106","author":"Laukkanen","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.jvs.2011.07.081_bib27","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1476-511X-9-23","article-title":"Comparative antilipidemic effect of N-acetylcysteine and sesame oil administration in diet-induced hypercholesterolemic mice","volume":"9","author":"Korou","year":"2010","journal-title":"Lipids Health Dis"},{"key":"10.1016\/j.jvs.2011.07.081_bib28","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1096\/fj.00-0526hyp","article-title":"Protective effects of N-acetylcysteine on lung injury and red blood cell modification induced by carrageenan in the rat","volume":"15","author":"Cuzzocrea","year":"2001","journal-title":"FASEB J"},{"key":"10.1016\/j.jvs.2011.07.081_bib29","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1016\/j.healun.2007.09.008","article-title":"N-acetyl cysteine pre-treatment attenuates inflammatory changes in the warm ischemic murine lung","volume":"26","author":"Geudens","year":"2007","journal-title":"J Heart Lung Transp"},{"key":"10.1016\/j.jvs.2011.07.081_bib30","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1056\/NEJM199505043321804","article-title":"Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers","volume":"332","author":"Morrow","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jvs.2011.07.081_bib31","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1161\/01.CIR.96.1.25","article-title":"High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells","volume":"96","author":"Cosentino","year":"1997","journal-title":"Circulation"},{"key":"10.1016\/j.jvs.2011.07.081_bib32","doi-asserted-by":"crossref","first-page":"409","DOI":"10.3109\/10715769109093429","article-title":"Detection of free radicals and cholesterol hydroperoxides in blood taken from the coronary sinus of man during percutaneous transluminal coronary angioplasty","volume":"14","author":"Coghlan","year":"1991","journal-title":"Free Radic Res Commun"},{"key":"10.1016\/j.jvs.2011.07.081_bib33","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.prp.2005.12.011","article-title":"Different inflammatory response and oxidative stress in neointimal hyperplasia after balloon angioplasty and stent implantation in cholesterol-fed rabbits","volume":"202","author":"Kawamoto","year":"2006","journal-title":"Pathol Researc Practice"}],"container-title":["Journal of Vascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741521411018362?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741521411018362?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,19]],"date-time":"2019-06-19T01:10:11Z","timestamp":1560906611000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0741521411018362"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["S0741521411018362"],"URL":"https:\/\/doi.org\/10.1016\/j.jvs.2011.07.081","relation":{},"ISSN":["0741-5214"],"issn-type":[{"value":"0741-5214","type":"print"}],"subject":[],"published":{"date-parts":[[2012,2]]}}}