{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T20:54:31Z","timestamp":1790801671812,"version":"4.1.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"vor","delay-in-days":731,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jvascsurg.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Vascular Surgery"],"published-print":{"date-parts":[[2018,3]]},"DOI":"10.1016\/j.jvs.2017.07.112","type":"journal-article","created":{"date-parts":[[2017,10,12]],"date-time":"2017-10-12T14:58:47Z","timestamp":1507820327000},"page":"809-816.e1","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Atherosclerotic plaque characteristics are not associated with future cardiovascular events in patients undergoing iliofemoral endarterectomy"],"prefix":"10.1016","volume":"67","author":[{"given":"Steven T.W.","family":"van Haelst","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saskia","family":"Haitjema","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wouter","family":"Derksen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"van Koeverden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Paul P.M.","family":"de Vries","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frans L.","family":"Moll","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hester M.","family":"den Ruijter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerard","family":"Pasterkamp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gert J.","family":"de Borst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jvs.2017.07.112_bib1","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1177\/1526602815592206","article-title":"An update on methods for revascularization and expansion of the TASC lesion classification to include below-the-knee arteries: a supplement to the Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II)","volume":"22","author":"Jaff","year":"2015","journal-title":"J\u00a0Endovasc Ther"},{"issue":"Suppl 1","key":"10.1016\/j.jvs.2017.07.112_bib2","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.ejvs.2006.09.024","article-title":"Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II)","volume":"33","author":"Norgren","year":"2007","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.jvs.2017.07.112_bib3","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1253\/circj.CJ-15-0199","article-title":"Primary stenting in femoropopliteal occlusive disease: what is the appropriate role?","volume":"79","author":"Yiu","year":"2015","journal-title":"Circ J"},{"key":"10.1016\/j.jvs.2017.07.112_bib4","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/S0140-6736(13)61249-0","article-title":"Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysis","volume":"382","author":"Fowkes","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.jvs.2017.07.112_bib5","doi-asserted-by":"crossref","first-page":"2197","DOI":"10.1016\/S0140-6736(12)61689-4","article-title":"Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010","volume":"380","author":"Murray","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.jvs.2017.07.112_bib6","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1001\/jama.300.2.197","article-title":"Ankle brachial index combined with framingham risk score to predict cardiovascular events and mortality: a meta-analysis","volume":"300","author":"Fowkes","year":"2008","journal-title":"JAMA"},{"key":"10.1016\/j.jvs.2017.07.112_bib7","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1177\/1089253210371518","article-title":"New predictors of adverse cardiovascular events following vascular surgery","volume":"14","author":"Van Lammeren","year":"2010","journal-title":"Semin Cardiothorac Vasc Anesth"},{"key":"10.1016\/j.jvs.2017.07.112_bib8","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1161\/01.CIR.0000087481.55887.C9","article-title":"From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: part II","volume":"108","author":"Naghavi","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.jvs.2017.07.112_bib9","first-page":"2984","article-title":"Requiem for the \u201cvulnerable plaque.\u201d","volume":"36","author":"Libby","year":"2015","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jvs.2017.07.112_bib10","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1161\/CIRCULATIONAHA.109.887497","article-title":"Composition of carotid atherosclerotic plaque is associated with cardiovascular outcome: a prognostic study","volume":"121","author":"Hellings","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.jvs.2017.07.112_bib11","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1161\/ATVBAHA.109.194944","article-title":"Local atherosclerotic plaques are a source of prognostic biomarkers for adverse cardiovascular events","volume":"30","author":"De Kleijn","year":"2010","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jvs.2017.07.112_bib12","doi-asserted-by":"crossref","first-page":"2320","DOI":"10.1161\/CIRCULATIONAHA.105.589044","article-title":"Histological assessment of 526 symptomatic carotid plaques in relation to the nature and timing of ischemic symptoms: the Oxford Plaque Study","volume":"113","author":"Redgrave","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.jvs.2017.07.112_bib13","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1001\/jama.299.5.547","article-title":"Atherosclerotic plaque composition and occurrence of restenosis after carotid endarterectomy","volume":"299","author":"Hellings","year":"2008","journal-title":"JAMA"},{"key":"10.1016\/j.jvs.2017.07.112_bib14","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/j.jvs.2010.03.063","article-title":"Histologic atherosclerotic plaque characteristics are associated with restenosis rates after endarterectomy of the common and superficial femoral arteries","volume":"52","author":"Derksen","year":"2010","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2017.07.112_bib15","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.atherosclerosis.2012.05.023","article-title":"Plaque characteristics and arterial remodeling in coronary and peripheral arterial systems","volume":"223","author":"Matsuo","year":"2012","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jvs.2017.07.112_bib16","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.jvs.2007.10.037","article-title":"Plaque in superficial femoral arteries indicates generalized atherosclerosis and vulnerability to coronary death: an autopsy study","volume":"47","author":"Dalager","year":"2008","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2017.07.112_bib17","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.advms.2015.03.003","article-title":"Histomorphological evaluation of atherosclerotic lesions in patients with peripheral artery occlusive disease","volume":"60","author":"Zimmermann","year":"2015","journal-title":"Adv Med Sci"},{"key":"10.1016\/j.jvs.2017.07.112_bib18","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0735-1097(10)80071-3","article-title":"Primary peripheral arterial stenoses and restenoses excised by transluminal atherectomy: a histopathologic study","volume":"15","author":"Johnson","year":"1990","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jvs.2017.07.112_bib19","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1016\/j.jvs.2008.11.096","article-title":"Characterization of primary and restenotic atherosclerotic plaque from the superficial femoral artery: potential role of Smad3 in regulation of SMC proliferation","volume":"49","author":"Edlin","year":"2009","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2017.07.112_bib20","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.jvs.2016.06.110","article-title":"Patients with diabetes differ in atherosclerotic plaque characteristics and have worse clinical outcome after iliofemoral endarterectomy compared with patients without diabetes","volume":"65","author":"Van Haelst","year":"2016","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2017.07.112_bib21","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.atherosclerosis.2014.08.034","article-title":"High-risk plaque in the superficial femoral artery of people with peripheral artery disease: prevalence and associated clinical characteristics","volume":"237","author":"Polonsky","year":"2014","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jvs.2017.07.112_bib22","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1007\/s10554-012-0124-3","article-title":"Association between conventional risk factors and different ultrasound-based markers of atherosclerosis at carotid and femoral levels in a middle-aged population","volume":"29","author":"Yerly","year":"2013","journal-title":"Int J Cardiovasc Imaging"},{"key":"10.1016\/j.jvs.2017.07.112_bib23","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s12410-012-9175-z","article-title":"MRI in lower extremity peripheral arterial disease: recent advancements","volume":"6","author":"Pollak","year":"2013","journal-title":"Curr Cardiovasc Imaging Rep"},{"key":"10.1016\/j.jvs.2017.07.112_bib24","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1161\/STROKEAHA.107.496703","article-title":"Histological characterization of restenotic carotid plaques in relation to recurrence interval and clinical presentation: a cohort study","volume":"39","author":"Hellings","year":"2008","journal-title":"Stroke"},{"key":"10.1016\/j.jvs.2017.07.112_bib25","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1007\/s10564-004-2304-6","article-title":"Athero-express: differential atherosclerotic plaque expression of mRNA and protein in relation to cardiovascular events and patient characteristics. Rationale and design","volume":"19","author":"Verhoeven","year":"2004","journal-title":"Eur J Epidemiol"},{"key":"10.1016\/j.jvs.2017.07.112_bib26","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.atherosclerosis.2016.10.039","article-title":"Time-dependent changes in femoral artery plaque characteristics of peripheral arterial disease patients","volume":"255","author":"Haitjema","year":"2016","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jvs.2017.07.112_bib27","doi-asserted-by":"crossref","first-page":"e115907","DOI":"10.1371\/journal.pone.0115907","article-title":"High reproducibility of histological characterization by whole virtual slide quantification; an example using carotid plaque specimens","volume":"9","author":"Vrijenhoek","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jvs.2017.07.112_bib28","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1016\/j.jvs.2007.08.018","article-title":"Intraobserver and interobserver variability and spatial differences in histologic examination of carotid endarterectomy specimens","volume":"46","author":"Hellings","year":"2007","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2017.07.112_bib29","first-page":"CD005263","article-title":"Supervised exercise therapy versus non-supervised exercise therapy for intermittent claudication","author":"Fokkenrood","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jvs.2017.07.112_bib30","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/S0140-6736(04)15785-1","article-title":"Endarterectomy for symptomatic carotid stenosis in relation to clinical subgroups and timing of surgery","volume":"363","author":"Rothwell","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.jvs.2017.07.112_bib31","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1161\/STROKEAHA.114.007221","article-title":"Symptomatic carotid atherosclerotic disease correlations between plaque composition and ipsilateral stroke risk","volume":"46","author":"Howard","year":"2015","journal-title":"Stroke"},{"key":"10.1016\/j.jvs.2017.07.112_bib32","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1159\/000136900","article-title":"Histological features of symptomatic carotid plaques in patients with impaired glucose tolerance and diabetes (Oxford Plaque Study)","volume":"26","author":"Redgrave","year":"2008","journal-title":"Cerebrovasc Dis"},{"key":"10.1016\/j.jvs.2017.07.112_bib33","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/j.jvs.2005.08.009","article-title":"Carotid atherosclerotic plaques in patients with transient ischemic attacks and stroke have unstable characteristics compared with plaques in asymptomatic and amaurosis fugax patients","volume":"42","author":"Verhoeven","year":"2005","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2017.07.112_bib34","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1161\/STROKEAHA.112.678672","article-title":"Histological features of carotid plaque in patients with ocular ischemia versus cerebral events","volume":"44","author":"Howard","year":"2013","journal-title":"Stroke"},{"key":"10.1016\/j.jvs.2017.07.112_bib35","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1161\/CIRCULATIONAHA.114.013797","article-title":"How does cardiovascular disease first present in women and men?","volume":"132","author":"George","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.jvs.2017.07.112_bib36","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1093\/eurheartj\/ehv044","article-title":"TLR2 and neutrophils potentiate endothelial stress, apoptosis and detachment: implications for superficial erosion","volume":"36","author":"Quillard","year":"2015","journal-title":"Eur Heart J"}],"container-title":["Journal of Vascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741521417320256?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741521417320256?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T20:19:32Z","timestamp":1760041172000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0741521417320256"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":36,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["S0741521417320256"],"URL":"https:\/\/doi.org\/10.1016\/j.jvs.2017.07.112","relation":{},"ISSN":["0741-5214"],"issn-type":[{"value":"0741-5214","type":"print"}],"subject":[],"published":{"date-parts":[[2018,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Atherosclerotic plaque characteristics are not associated with future cardiovascular events in patients undergoing iliofemoral endarterectomy","name":"articletitle","label":"Article Title"},{"value":"Journal of Vascular Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jvs.2017.07.112","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 by the Society for Vascular Surgery. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}