{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T07:10:46Z","timestamp":1763017846122,"version":"build-2065373602"},"reference-count":48,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"vor","delay-in-days":731,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jvascsurg.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Vascular Surgery"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1016\/j.jvs.2017.11.090","type":"journal-article","created":{"date-parts":[[2018,3,5]],"date-time":"2018-03-05T18:27:47Z","timestamp":1520274467000},"page":"60S-71S.e3","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"S","title":["Exploring antibody-dependent adaptive immunity against aortic extracellular matrix components in experimental aortic aneurysms"],"prefix":"10.1016","volume":"68","author":[{"given":"Rapha\u00ebl","family":"Coscas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastien","family":"Dupont","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sacha","family":"Mussot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liliane","family":"Louedec","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harry","family":"Etienne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marion","family":"Morvan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilles","family":"Chiocchia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziad","family":"Massy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie-Paule","family":"Jacob","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Baptiste","family":"Michel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jvs.2017.11.090_bib1","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1093\/cvr\/cvq337","article-title":"Novel aspects of the pathogenesis of aneurysms of the abdominal aorta in humans","volume":"90","author":"Michel","year":"2011","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.jvs.2017.11.090_bib2","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/nrcardio.2010.180","article-title":"Pathophysiology and epidemiology of abdominal aortic aneurysms","volume":"8","author":"Nordon","year":"2011","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.jvs.2017.11.090_bib3","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1016\/S0002-9440(10)63766-2","article-title":"Role of leukocyte elastase in preventing cellular re-colonization of the mural thrombus","volume":"164","author":"Fontaine","year":"2004","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jvs.2017.11.090_bib4","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1016\/S0002-9440(10)64447-1","article-title":"Involvement of the mural thrombus as a site of protease release and activation in human aortic aneurysms","volume":"161","author":"Fontaine","year":"2002","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jvs.2017.11.090_bib5","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1161\/ATVBAHA.115.305269","article-title":"Inflammatory cell phenotypes in AAAs: their role and potential as targets for therapy","volume":"35","author":"Dale","year":"2015","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jvs.2017.11.090_bib6","doi-asserted-by":"crossref","first-page":"4897","DOI":"10.4049\/jimmunol.1301009","article-title":"Aneurysmal lesions of patients with abdominal aortic aneurysm contain clonally expanded T cells","volume":"192","author":"Lu","year":"2014","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.jvs.2017.11.090_bib7","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1161\/01.ATV.0000200380.73876.d9","article-title":"Reduced immunoregulatory CD31+ T cells in patients with atherosclerotic abdominal aortic aneurysm","volume":"26","author":"Caligiuri","year":"2006","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jvs.2017.11.090_bib8","doi-asserted-by":"crossref","first-page":"4007","DOI":"10.2174\/1381612821666150826093855","article-title":"Monocytes, macrophages and other inflammatory mediators of abdominal aortic aneurysm","volume":"21","author":"Potteaux","year":"2015","journal-title":"Curr Pharm Des"},{"key":"10.1016\/j.jvs.2017.11.090_bib9","doi-asserted-by":"crossref","first-page":"11178","DOI":"10.3390\/ijms160511178","article-title":"Clonal expansion of T cells in abdominal aortic aneurysm: a role for doxycycline as drug of choice?","volume":"16","author":"Kroon","year":"2015","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jvs.2017.11.090_bib10","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1161\/ATVBAHA.110.213157","article-title":"Mast cells: important players in the orchestrated pathogenesis of abdominal aortic aneurysms","volume":"31","author":"Swedenborg","year":"2011","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jvs.2017.11.090_bib11","first-page":"1199","article-title":"Human abdominal aortic aneurysms. Immunophenotypic analysis suggesting an immune-mediated response","volume":"137","author":"Koch","year":"1990","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jvs.2017.11.090_bib12","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1093\/ajcp\/85.1.21","article-title":"Plasma cell infiltrates in atherosclerotic abdominal aortic aneurysms","volume":"85","author":"Beckman","year":"1986","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.jvs.2017.11.090_bib13","doi-asserted-by":"crossref","first-page":"2374","DOI":"10.1161\/ATVBAHA.113.301280","article-title":"Natural regulatory T cells limit angiotensin II-induced aneurysm formation and rupture in mice","volume":"33","author":"Ait-Oufella","year":"2013","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jvs.2017.11.090_bib14","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1001\/archsurg.1996.01430130087017","article-title":"Features of autoimmunity in the abdominal aortic aneurysm","volume":"131","author":"Gregory","year":"1996","journal-title":"Arch Surg"},{"key":"10.1016\/j.jvs.2017.11.090_bib15","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1006\/jsre.1996.0339","article-title":"Complement activation and subclassification of tissue immunoglobulin G in the abdominal aortic aneurysm","volume":"65","author":"Capella","year":"1996","journal-title":"J\u00a0Surg Res"},{"key":"10.1016\/j.jvs.2017.11.090_bib16","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/S0741-5214(05)80007-2","article-title":"Medial neovascularization in abdominal aortic aneurysms: a histopathologic marker of aneurysmal degeneration with pathophysiologic implications","volume":"21","author":"Holmes","year":"1995","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2017.11.090_bib17","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0021-9150(00)00441-X","article-title":"Vascular-associated lymphoid tissue (VALT) involvement in aortic aneurysm","volume":"154","author":"Bobryshev","year":"2001","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jvs.2017.11.090_bib18","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.atherosclerosis.2015.07.036","article-title":"B\u00a0lymphocytes in abdominal aortic aneurysms","volume":"242","author":"Zhang","year":"2015","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jvs.2017.11.090_bib19","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1161\/CIRCULATIONAHA.114.010988","article-title":"Control of the T follicular helper-germinal center B-cell axis by CD8+ regulatory T cells limits atherosclerosis and tertiary lymphoid organ development","volume":"131","author":"Clement","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.jvs.2017.11.090_bib20","first-page":"40","article-title":"Angiogenesis is associated with mononuclear inflammatory cells in abdominal aortic aneurysms","volume":"87","author":"Satta","year":"1998","journal-title":"Ann Chir Gynaecol"},{"key":"10.1016\/j.jvs.2017.11.090_bib21","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1067\/mva.2002.120382","article-title":"Monocyte chemotactic activity in human abdominal aortic aneurysms: role of elastin degradation peptides and the 67-kD cell surface elastin receptor","volume":"35","author":"Hance","year":"2002","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2017.11.090_bib22","doi-asserted-by":"crossref","first-page":"H719","DOI":"10.1152\/ajpheart.00273.2015","article-title":"Exploring autoimmunity in the pathogenesis of abdominal aortic aneurysms","volume":"309","author":"Chang","year":"2015","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.jvs.2017.11.090_bib23","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1097\/00007890-199609270-00017","article-title":"Cell and extracellular matrix rejection in arterial concordant and discordant xenografts in the rat","volume":"62","author":"Allaire","year":"1996","journal-title":"Transplantation"},{"key":"10.1016\/j.jvs.2017.11.090_bib24","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/S0741-5214(94)70071-0","article-title":"Cell-free arterial grafts: morphologic characteristics of aortic isografts, allografts, and xenografts in rats","volume":"19","author":"Allaire","year":"1994","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2017.11.090_bib25","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1097\/00007890-199509000-00003","article-title":"Sequential immunological targeting of chronic experimental arterial allograft","volume":"60","author":"Plissonnier","year":"1995","journal-title":"Transplantation"},{"key":"10.1016\/j.jvs.2017.11.090_bib26","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1189\/jlb.1106671","article-title":"Involvement of intraplaque hemorrhage in atherothrombosis evolution via neutrophil protease enrichment","volume":"82","author":"Leclercq","year":"2007","journal-title":"J\u00a0Leukoc Biol"},{"key":"10.1016\/j.jvs.2017.11.090_bib27","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1161\/ATVBAHA.116.308534","article-title":"Translational relevance and recent advances of animal models of abdominal aortic aneurysm","volume":"37","author":"Senemaud","year":"2017","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jvs.2017.11.090_bib28","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1172\/JCI2909","article-title":"Local overexpression of TIMP-1 prevents aortic aneurysm degeneration and rupture in a rat model","volume":"102","author":"Allaire","year":"1998","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.jvs.2017.11.090_bib29","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/BF02329378","article-title":"The role of inflammation in nonspecific abdominal aortic aneurysm disease","volume":"5","author":"Brophy","year":"1991","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.jvs.2017.11.090_bib30","doi-asserted-by":"crossref","first-page":"89","DOI":"10.2217\/fca.12.71","article-title":"Cysteine protease cathepsins and matrix metalloproteinases in the development of abdominal aortic aneurysms","volume":"9","author":"Qin","year":"2013","journal-title":"Future Cardiol"},{"key":"10.1016\/j.jvs.2017.11.090_bib31","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/978-1-4939-2999-3_2","article-title":"The structure of natural and recombinant antibodies","volume":"1348","author":"Ma","year":"2015","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.jvs.2017.11.090_bib32","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.intimp.2013.06.034","article-title":"Neutrophil cell surface receptors and their intracellular signal transduction pathways","volume":"17","author":"Futosi","year":"2013","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.jvs.2017.11.090_bib33","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1161\/CIRCULATIONAHA.108.832972","article-title":"Complement-dependent neutrophil recruitment is critical for the development of elastase-induced abdominal aortic aneurysm","volume":"119","author":"Pagano","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.jvs.2017.11.090_bib34","doi-asserted-by":"crossref","first-page":"2209","DOI":"10.1161\/CIRCULATIONAHA.108.806505","article-title":"Clinical trial of doxycycline for matrix metalloproteinase-9 inhibition in patients with an abdominal aneurysm: doxycycline selectively depletes aortic wall neutrophils and cytotoxic T cells","volume":"119","author":"Lindeman","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.jvs.2017.11.090_bib35","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1097\/SLA.0000000000000602","article-title":"Increased 18F-FDG uptake is predictive of rupture in a novel rat abdominal aortic aneurysm rupture model","volume":"261","author":"English","year":"2015","journal-title":"Ann Surg"},{"key":"10.1016\/j.jvs.2017.11.090_bib36","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1111\/j.1365-2141.2007.06632.x","article-title":"Platelets release active matrix metalloproteinase-2 in\u00a0vivo in humans at a site of vascular injury: lack of inhibition by aspirin","volume":"138","author":"Falcinelli","year":"2007","journal-title":"Br J Haematol"},{"key":"10.1016\/j.jvs.2017.11.090_bib37","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1159\/000265569","article-title":"Thrombus versus wall biological activities in experimental aortic aneurysms","volume":"47","author":"Coutard","year":"2010","journal-title":"J\u00a0Vasc Res"},{"key":"10.1016\/j.jvs.2017.11.090_bib38","doi-asserted-by":"crossref","first-page":"E4335","DOI":"10.1073\/pnas.1315512110","article-title":"Fibrinogen-specific antibody induces abdominal aortic aneurysm in mice through complement lectin pathway activation","volume":"110","author":"Zhou","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jvs.2017.11.090_bib39","doi-asserted-by":"crossref","first-page":"E415","DOI":"10.1073\/pnas.1119000109","article-title":"Antibody directs properdin-dependent activation of the complement alternative pathway in a mouse model of abdominal aortic aneurysm","volume":"109","author":"Zhou","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jvs.2017.11.090_bib40","doi-asserted-by":"crossref","first-page":"38477","DOI":"10.1038\/srep38477","article-title":"Quantitative HDL proteomics identifies peroxiredoxin-6 as a biomarker of human abdominal aortic aneurysm","volume":"6","author":"Burillo","year":"2016","journal-title":"Sci Rep"},{"key":"10.1016\/j.jvs.2017.11.090_bib41","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0022-4804(03)00208-7","article-title":"The role of a putative microfibrillar protein (80 kDa) in abdominal aortic aneurysm disease","volume":"114","author":"Chew","year":"2003","journal-title":"J\u00a0Surg Res"},{"key":"10.1016\/j.jvs.2017.11.090_bib42","first-page":"Unit 10.1","article-title":"Overview of extracellular matrix","volume":"Chapter 10","author":"Mecham","year":"2012","journal-title":"Curr Protoc Cell Biol"},{"key":"10.1016\/j.jvs.2017.11.090_bib43","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1006\/bbrc.1996.0177","article-title":"Partial amino acid sequence of a novel 40-kDa human aortic protein, with vitronectin-like, fibrinogen-like, and calcium binding domains: aortic aneurysm-associated protein-40 (AAAP-40) [human MAGP-3, proposed]","volume":"219","author":"Xia","year":"1996","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.jvs.2017.11.090_bib44","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1016\/j.humimm.2013.02.009","article-title":"Autoantigenicity of carbonic anhydrase 1 in patients with abdominal aortic aneurysm, revealed by proteomic surveillance","volume":"74","author":"Ando","year":"2013","journal-title":"Hum Immunol"},{"key":"10.1016\/j.jvs.2017.11.090_bib45","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/0022-4804(90)90202-D","article-title":"Longitudinal retractive force in pressurized dog and human arteries","volume":"48","author":"Dobrin","year":"1990","journal-title":"J\u00a0Surg Res"},{"key":"10.1016\/j.jvs.2017.11.090_bib46","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1161\/ATVBAHA.110.207522","article-title":"Signaling during platelet adhesion and activation","volume":"30","author":"Li","year":"2010","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jvs.2017.11.090_bib47","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1007\/s10753-015-0284-0","article-title":"Antibodies to type IV collagen induce type 1 autoimmune pancreatitis","volume":"39","author":"Liu","year":"2016","journal-title":"Inflammation"},{"key":"10.1016\/j.jvs.2017.11.090_bib48","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1136\/hrt.2010.212100","article-title":"The translational science of Marfan syndrome","volume":"97","author":"Jondeau","year":"2011","journal-title":"Heart"}],"container-title":["Journal of Vascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741521418301253?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741521418301253?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T20:23:02Z","timestamp":1760041382000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0741521418301253"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":48,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["S0741521418301253"],"URL":"https:\/\/doi.org\/10.1016\/j.jvs.2017.11.090","relation":{},"ISSN":["0741-5214"],"issn-type":[{"type":"print","value":"0741-5214"}],"subject":[],"published":{"date-parts":[[2018,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Exploring antibody-dependent adaptive immunity against aortic extracellular matrix components in experimental aortic aneurysms","name":"articletitle","label":"Article Title"},{"value":"Journal of Vascular Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jvs.2017.11.090","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier Inc. on behalf of the Society for Vascular Surgery.","name":"copyright","label":"Copyright"}]}}