{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:51:46Z","timestamp":1782604306089,"version":"3.54.5"},"reference-count":38,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"vor","delay-in-days":731,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100003550","name":"Queensland Government","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003550","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1117061"],"award-info":[{"award-number":["1117061"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jvascsurg.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Vascular Surgery"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1016\/j.jvs.2019.03.057","type":"journal-article","created":{"date-parts":[[2019,7,18]],"date-time":"2019-07-18T08:27:36Z","timestamp":1563438456000},"page":"2065-2073.e10","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"title":["Systematic review and meta-analysis of the association between intraluminal thrombus volume and abdominal aortic aneurysm rupture"],"prefix":"10.1016","volume":"70","author":[{"given":"Tejas P.","family":"Singh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon A.","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph V.","family":"Moxon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. Christian","family":"Gasser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Golledge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jvs.2019.03.057_bib1","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1016\/S0140-6736(98)10137-X","article-title":"Mortality results for randomised controlled trial of early elective surgery or ultrasonographic surveillance for small abdominal aortic aneurysms. The UK Small Aneurysm Trial Participants","volume":"352","author":"Greenhalgh","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.jvs.2019.03.057_bib2","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.ejvs.2010.09.011","article-title":"Management of abdominal aortic aneurysms clinical practice guidelines of the European Society for Vascular Surgery","volume":"41","author":"Moll","year":"2011","journal-title":"Eur J Vasc Endovascular Surg"},{"key":"10.1016\/j.jvs.2019.03.057_bib3","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1002\/bjs.6779","article-title":"Growth rates of small abdominal aortic aneurysms correlate with clinical events","volume":"97","author":"Thompson","year":"2010","journal-title":"Br J Surg"},{"key":"10.1016\/j.jvs.2019.03.057_bib4","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.ejvs.2010.08.026","article-title":"Comparison of surveillance versus aortic endografting for small aneurysm repair (CAESAR): results from a randomised trial","volume":"41","author":"Cao","year":"2011","journal-title":"Eur J Vasc Endovascular Surg"},{"key":"10.1016\/j.jvs.2019.03.057_bib5","doi-asserted-by":"crossref","first-page":"19","DOI":"10.3389\/fcvm.2015.00019","article-title":"The abdominal aortic aneurysm and intraluminal thrombus: current concepts of development and treatment","volume":"2","author":"Piechota-Polanczyk","year":"2015","journal-title":"Front Cardiovasc Med"},{"key":"10.1016\/j.jvs.2019.03.057_bib6","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1067\/mva.2002.126087","article-title":"Effect of intraluminal thrombus on wall stress in patient-specific models of abdominal aortic aneurysm","volume":"36","author":"Wang","year":"2002","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2019.03.057_bib7","first-page":"67","article-title":"Effect of thrombus on abdominal aortic aneurysm wall dilation and stress","volume":"44","author":"Thubrikar","year":"2003","journal-title":"J\u00a0Cardiovasc Surg (Torino)"},{"key":"10.1016\/j.jvs.2019.03.057_bib8","first-page":"325","article-title":"The influence of intraluminal thrombus on abdominal aortic aneurysm wall stress","volume":"28","author":"Georgakarakos","year":"2009","journal-title":"Int Angiol"},{"key":"10.1016\/j.jvs.2019.03.057_bib9","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.ejvs.2014.05.014","article-title":"Mural thrombus and the progression of abdominal aortic aneurysms: a large population-based prospective cohort study","volume":"48","author":"Behr-Rasmussen","year":"2014","journal-title":"Eur J Vasc Endovascular Surg"},{"key":"10.1016\/j.jvs.2019.03.057_bib10","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.jvs.2010.08.013","article-title":"Thrombus volume is associated with cardiovascular events and aneurysm growth in patients who have abdominal aortic aneurysms","volume":"53","author":"Parr","year":"2011","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2019.03.057_bib11","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1016\/j.jvs.2017.08.069","article-title":"Intraluminal thrombus is associated with early rupture of abdominal aortic aneurysm","volume":"67","author":"Haller","year":"2018","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2019.03.057_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2046-4053-4-1","article-title":"Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement","volume":"4","author":"Moher","year":"2015","journal-title":"Syst Rev"},{"key":"10.1016\/j.jvs.2019.03.057_bib13","author":"Singh"},{"key":"10.1016\/j.jvs.2019.03.057_bib14","series-title":"Standard quality assessment criteria for evaluating primary research papers from a variety of fields","author":"Kmet","year":"2004"},{"key":"10.1016\/j.jvs.2019.03.057_bib15","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1007\/s10654-010-9491-z","article-title":"Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses","volume":"25","author":"Stang","year":"2010","journal-title":"Eur J Epidemiol"},{"key":"10.1016\/j.jvs.2019.03.057_bib16","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1002\/bjs.8707","article-title":"Meta-analysis of individual patient data to examine factors affecting growth and rupture of small abdominal aortic aneurysms","volume":"99","author":"Sweeting","year":"2012","journal-title":"Br J Surg"},{"key":"10.1016\/j.jvs.2019.03.057_bib17","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1471-2288-5-13","article-title":"Estimating the mean and variance from the median, range, and the size of a sample","volume":"5","author":"Hozo","year":"2005","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.jvs.2019.03.057_bib18","author":"Higgins J. Green S (editors)"},{"key":"10.1016\/j.jvs.2019.03.057_bib19","first-page":"719","article-title":"Statistical aspects of the analysis of data from retrospective studies of disease","volume":"22","author":"Mantel","year":"1959","journal-title":"J\u00a0Natl Cancer Inst"},{"key":"10.1016\/j.jvs.2019.03.057_bib20","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1002\/sim.1186","article-title":"Quantifying heterogeneity in a meta-analysis","volume":"21","author":"Higgins","year":"2002","journal-title":"Stat Med"},{"key":"10.1016\/j.jvs.2019.03.057_bib21","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/S0895-4356(00)00242-0","article-title":"Publication and related bias in meta-analysis: power of statistical tests and prevalence in the literature","volume":"53","author":"Sterne","year":"2000","journal-title":"J\u00a0Clin Epidemiol"},{"key":"10.1016\/j.jvs.2019.03.057_bib22","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.jvs.2005.01.004","article-title":"Size and location of thrombus in intact and ruptured abdominal aortic aneurysms","volume":"41","author":"Hans","year":"2005","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2019.03.057_bib23","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.ejvs.2010.04.003","article-title":"Biomechanical rupture risk assessment of abdominal aortic aneurysms: model complexity versus predictability of finite element simulations","volume":"40","author":"Gasser","year":"2010","journal-title":"Eur J Vasc Endovascular Surg"},{"key":"10.1016\/j.jvs.2019.03.057_bib24","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.ejvs.2014.11.010","article-title":"Finite element analysis in asymptomatic, symptomatic, and ruptured abdominal aortic aneurysms: in search of new rupture risk predictors","volume":"49","author":"Erhart","year":"2015","journal-title":"Eur J Vasc Endovascular Surg"},{"key":"10.1016\/j.jvs.2019.03.057_bib25","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1177\/1526602815612196","article-title":"Prediction of rupture sites in abdominal aortic aneurysms after finite element analysis","volume":"23","author":"Erhart","year":"2016","journal-title":"J\u00a0Endovasc Ther"},{"key":"10.1016\/j.jvs.2019.03.057_bib26","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.jvs.2013.08.036","article-title":"Thrombus volume is similar in patients with ruptured and intact abdominal aortic aneurysms","volume":"59","author":"Golledge","year":"2014","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2019.03.057_bib27","doi-asserted-by":"crossref","first-page":"e0202672","DOI":"10.1371\/journal.pone.0202672","article-title":"Additional value of biomechanical indices based on CTa for rupture risk assessment of abdominal aortic aneurysms","volume":"13","author":"Leemans","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.jvs.2019.03.057_bib28","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1177\/1526602818808292","article-title":"Aortic lumen area is increased in ruptured abdominal aortic aneurysms and correlates to biomechanical rupture risk","volume":"25","author":"Siika","year":"2018","journal-title":"J\u00a0Endovasc Ther"},{"key":"10.1016\/j.jvs.2019.03.057_bib29","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.jvs.2011.08.012","article-title":"Preliminary intraobserver and interobserver variability in wall stress and rupture risk assessment of abdominal aortic aneurysms using a semiautomatic finite element model","volume":"55","author":"Teutelink","year":"2012","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2019.03.057_bib30","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1161\/01.CIR.0000133279.07468.9F","article-title":"Abdominal aortic aneurysm expansion: risk factors and time intervals for surveillance","volume":"110","author":"Brady","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.jvs.2019.03.057_bib31","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/S0741-5214(95)70222-9","article-title":"Variability in measurement of abdominal aortic aneurysms","volume":"21","author":"Lederle","year":"1995","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2019.03.057_bib32","doi-asserted-by":"crossref","first-page":"2605","DOI":"10.1161\/01.ATV.0000245819.32762.cb","article-title":"Abdominal aortic aneurysms: pathophysiological mechanisms and clinical implications","volume":"26","author":"Golledge","year":"2006","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jvs.2019.03.057_bib33","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.jvs.2016.08.003","article-title":"Challenges and opportunities in limiting abdominal aortic aneurysm growth","volume":"65","author":"Golledge","year":"2017","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2019.03.057_bib34","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1177\/1526602815615821","article-title":"Commentary: computational biomechanics-based rupture prediction of abdominal aortic aneurysms","volume":"23","author":"Doyle","year":"2016","journal-title":"J\u00a0Endovasc Ther"},{"key":"10.1016\/j.jvs.2019.03.057_bib35","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1007\/s10439-015-1267-x","article-title":"On the impact of intraluminal thrombus mechanical behavior in AAA passive mechanics","volume":"43","author":"Riveros","year":"2015","journal-title":"Ann Biomed Eng"},{"key":"10.1016\/j.jvs.2019.03.057_bib36","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.ejvs.2010.12.010","article-title":"The impact of intraluminal thrombus failure on the mechanical stress in the wall of abdominal aortic aneurysms","volume":"41","author":"Polzer","year":"2011","journal-title":"Eur J Vasc Endovascular Surg"},{"key":"10.1016\/j.jvs.2019.03.057_bib37","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1016\/j.jvs.2008.06.063","article-title":"Bleeding into the intraluminal thrombus in abdominal aortic aneurysms is associated with rupture","volume":"48","author":"Roy","year":"2008","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2019.03.057_bib38","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.ejvs.2014.04.025","article-title":"Abdominal aortic aneurysms with high thrombus signal intensity on magnetic resonance imaging are associated with high growth rate","volume":"48","author":"Nguyen","year":"2014","journal-title":"Eur J Vasc Endovascular Surg"}],"container-title":["Journal of Vascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741521419311140?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741521419311140?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T10:10:58Z","timestamp":1778753458000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0741521419311140"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":38,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["S0741521419311140"],"URL":"https:\/\/doi.org\/10.1016\/j.jvs.2019.03.057","relation":{},"ISSN":["0741-5214"],"issn-type":[{"value":"0741-5214","type":"print"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Systematic review and meta-analysis of the association between intraluminal thrombus volume and abdominal aortic aneurysm rupture","name":"articletitle","label":"Article Title"},{"value":"Journal of Vascular Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jvs.2019.03.057","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Published by Elsevier Inc. on behalf of the Society for Vascular Surgery.","name":"copyright","label":"Copyright"}]}}