{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T11:27:40Z","timestamp":1790162860058,"version":"4.1.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"vor","delay-in-days":730,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jvascsurg.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Vascular Surgery"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1016\/j.jvs.2020.12.088","type":"journal-article","created":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T06:48:37Z","timestamp":1612507717000},"page":"489-498.e1","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["Impact of impaired ambulatory capacity on the outcomes of peripheral vascular interventions among patients with chronic limb-threating ischemia"],"prefix":"10.1016","volume":"74","author":[{"given":"Isaac N.","family":"Naazie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isibor","family":"Arhuidese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahsan","family":"Zil-E-Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey J.","family":"Siracuse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud B.","family":"Malas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jvs.2020.12.088_bib1","doi-asserted-by":"crossref","first-page":"3S","DOI":"10.1016\/j.jvs.2019.02.016","article-title":"Global vascular guidelines on the management of chronic limb-threatening ischemia","volume":"69","author":"Conte","year":"2019","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2020.12.088_bib2","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/S0140-6736(13)61249-0","article-title":"Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysis","volume":"382","author":"Fowkes","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.jvs.2020.12.088_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.jvs.2014.03.290","article-title":"Epidemiology of peripheral arterial disease and critical limb ischemia in an insured national population","volume":"60","author":"Nehler","year":"2014","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2020.12.088_bib4","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1067\/mhj.2002.122871","article-title":"Prevalence and clinical correlates of peripheral arterial disease in the Framingham Offspring Study","volume":"143","author":"Murabito","year":"2002","journal-title":"Am Heart J"},{"key":"10.1016\/j.jvs.2020.12.088_bib5","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0021-9150(91)90014-T","article-title":"The ratio of ankle and arm arterial pressure as an independent predictor of mortality","volume":"87","author":"McKenna","year":"1991","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jvs.2020.12.088_bib6","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1056\/NEJM199202063260605","article-title":"Mortality over a period of 10 years in patients with peripheral arterial disease","volume":"326","author":"Criqui","year":"1992","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jvs.2020.12.088_bib7","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1016\/j.jvs.2015.07.065","article-title":"The natural history of untreated severe or critical limb ischemia","volume":"62","author":"Cambria","year":"2015","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2020.12.088_bib8","doi-asserted-by":"crossref","first-page":"e002938","DOI":"10.1161\/JAHA.115.002938","article-title":"Critical limb ischemia: current trends and future directions","volume":"5","author":"Teraa","year":"2016","journal-title":"J\u00a0Am Heart Assoc"},{"key":"10.1016\/j.jvs.2020.12.088_bib9","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1097\/01.RVI.0000137978.15352.C6","article-title":"Medical treatment of peripheral arterial disease: a comprehensive review","volume":"15","author":"Stoyioglou","year":"2004","journal-title":"J\u00a0Vasc Interv Radiol"},{"key":"10.1016\/j.jvs.2020.12.088_bib10","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1016\/j.jvs.2006.12.037","article-title":"Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II)","volume":"45","author":"Norgren","year":"2007","journal-title":"J\u00a0Vasc Surg"},{"issue":"Suppl. 2","key":"10.1016\/j.jvs.2020.12.088_bib11","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1016\/S1078-5884(11)60009-9","article-title":"Chapter I: definitions, epidemiology, clinical presentation and prognosis","volume":"42","author":"Becker","year":"2011","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.jvs.2020.12.088_bib12","doi-asserted-by":"crossref","first-page":"958965.e1","DOI":"10.1016\/j.jvs.2015.09.063","article-title":"Comparison of open and endovascular treatment of patients with critical limb ischemia in the Vascular Quality Initiative","volume":"63","author":"Siracuse","year":"2016","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2020.12.088_bib13","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1016\/j.avsg.2013.12.027","article-title":"Risk factors for protracted postoperative length of stay after lower extremity bypass for critical limb ischemia","volume":"28","author":"Siracuse","year":"2014","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.jvs.2020.12.088_bib14","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.jvs.2009.08.065","article-title":"Preoperative functional status predicts perioperative outcomes after infrainguinal bypass surgery","volume":"51","author":"Crawford","year":"2010","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2020.12.088_bib15","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1016\/j.jvs.2013.12.032","article-title":"Risk factors for readmission after lower extremity bypass in the American College of Surgeons National Surgery Quality Improvement Program","volume":"59","author":"Zhang","year":"2014","journal-title":"J\u00a0Vasc Surg"},{"issue":"5 Suppl","key":"10.1016\/j.jvs.2020.12.088_bib16","doi-asserted-by":"crossref","first-page":"52S","DOI":"10.1016\/j.jvs.2010.01.077","article-title":"Bypass versus Angioplasty in Severe Ischaemia of the Leg (BASIL) trial: a survival prediction model to facilitate clinical decision making","volume":"51","author":"Bradbury","year":"2010","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2020.12.088_bib17","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1016\/j.jvs.2012.09.083","article-title":"The comprehensive risk assessment for bypass (CRAB) facilitates efficient perioperative risk assessment for patients with critical limb ischemia","volume":"57","author":"Meltzer","year":"2013","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2020.12.088_bib18","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.ejvs.2017.07.018","article-title":"Editor\u2019s Choice \u2013 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS)","volume":"55","author":"Aboyans","year":"2018","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.jvs.2020.12.088_bib19","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1016\/j.jvs.2016.12.104","article-title":"The effect of ambulatory status on outcomes of percutaneous vascular interventions and lower extremity bypass for critical limb ischemia in the Vascular Quality Initiative","volume":"65","author":"Lu","year":"2017","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2020.12.088_bib20","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s00268-006-0242-y","article-title":"Risk-scoring method for prediction of 30-day postoperative outcome after infrainguinal surgical revascularization for critical lower-limb ischemia: a Finnvasc Registry Study","volume":"31","author":"Biancari","year":"2007","journal-title":"World J Surg"},{"key":"10.1016\/j.jvs.2020.12.088_bib21","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/j.jvs.2015.09.051","article-title":"A\u00a0comparative evaluation of risk-adjustment models for benchmarking amputation-free survival after lower extremity bypass","volume":"63","author":"Simons","year":"2016","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2020.12.088_bib22","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/j.jvs.2006.06.015","article-title":"Determinants of functional outcome after revascularization for critical limb ischemia: an analysis of 1000 consecutive vascular interventions","volume":"44","author":"Taylor","year":"2006","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2020.12.088_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.jvs.2009.02.014","article-title":"Predicting ambulation status one year after lower extremity bypass","volume":"49","author":"Goodney","year":"2009","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2020.12.088_bib24","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1016\/j.jvs.2008.07.062","article-title":"Risk stratification in critical limb ischemia: derivation and validation of a model to predict amputation-free survival using multicenter surgical outcomes data","volume":"48","author":"Schanzer","year":"2008","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2020.12.088_bib25","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1016\/j.jcin.2014.06.018","article-title":"Two-year life expectancy in patients with critical limb ischemia","volume":"7","author":"Soga","year":"2014","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jvs.2020.12.088_bib26","first-page":"619","article-title":"Thru-knee amputation: the operation of choice for non-ambulatory patients","volume":"59","author":"Ayoub","year":"1993","journal-title":"Am Surg"},{"key":"10.1016\/j.jvs.2020.12.088_bib27","author":"Taylor"},{"key":"10.1016\/j.jvs.2020.12.088_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.jvs.2013.08.003","article-title":"The Society for Vascular Surgery lower extremity threatened limb classification system: risk stratification based on Wound, Ischemia, and foot Infection (WIfI)","volume":"59","author":"Mills","year":"2014","journal-title":"J\u00a0Vasc Surg"}],"container-title":["Journal of Vascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741521421001397?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741521421001397?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T20:32:00Z","timestamp":1760041920000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0741521421001397"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":28,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["S0741521421001397"],"URL":"https:\/\/doi.org\/10.1016\/j.jvs.2020.12.088","relation":{},"ISSN":["0741-5214"],"issn-type":[{"value":"0741-5214","type":"print"}],"subject":[],"published":{"date-parts":[[2021,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of impaired ambulatory capacity on the outcomes of peripheral vascular interventions among patients with chronic limb-threating ischemia","name":"articletitle","label":"Article Title"},{"value":"Journal of Vascular Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jvs.2020.12.088","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Published by Elsevier Inc. on behalf of the Society for Vascular Surgery.","name":"copyright","label":"Copyright"}]}}