{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T02:38:39Z","timestamp":1791859119836,"version":"4.3.4"},"reference-count":43,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"vor","delay-in-days":730,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jvascsurg.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Vascular Surgery"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.jvs.2021.05.025","type":"journal-article","created":{"date-parts":[[2021,5,31]],"date-time":"2021-05-31T02:04:05Z","timestamp":1622426645000},"page":"1659-1667","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"title":["Sex, age, and other barriers for prosthetic referral following amputation and the impact on survival"],"prefix":"10.1016","volume":"74","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1627-5434","authenticated-orcid":false,"given":"William","family":"Shutze","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"Gable","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald","family":"Ogola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tasnim","family":"Yasin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niyata","family":"Madhukar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhuvanna","family":"Kamma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yousif","family":"Alniemi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Eidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jvs.2021.05.025_bib1","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1016\/j.jvs.2016.04.042","article-title":"Gangrene, amputation, and allogeneic transplantation in the fifth century ad: a pictorial representation","volume":"64","author":"Perciaccante","year":"2016","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2021.05.025_bib2","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.avsg.2018.10.038","article-title":"The majority of patients have diagnostic evaluation prior to major lower extremity amputation","volume":"58","author":"Hardy","year":"2019","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.jvs.2021.05.025_bib3","first-page":"20","article-title":"More than one leg to stand on: a step forward in the management of critical limb ischemia","volume":"74","author":"Henry","year":"2009","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jvs.2021.05.025_bib4","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.apmr.2007.11.005","article-title":"Estimating the prevalence of limb loss in the United States: 2005 to 2050","volume":"89","author":"Ziegler-Graham","year":"2008","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.jvs.2021.05.025_bib5","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.avsg.2016.12.015","article-title":"A\u00a0meta-analysis of long-term mortality and associated risk factors following lower extremity amputation","volume":"42","author":"Stern","year":"2017","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.jvs.2021.05.025_bib6","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1053\/j.jfas.2016.01.012","article-title":"Mortality after nontraumatic major amputation among patients with diabetes and peripheral vascular disease: a systematic review","volume":"55","author":"Thorud","year":"2016","journal-title":"J\u00a0Foot Ankle Surg"},{"key":"10.1016\/j.jvs.2021.05.025_bib7","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1067\/msy.2001.115359","article-title":"Postoperative and late survival outcomes after major amputation: findings from the Department of Veterans Affairs National Surgical Quality Improvement Program","volume":"130","author":"Feinglass","year":"2001","journal-title":"Surgery"},{"key":"10.1016\/j.jvs.2021.05.025_bib8","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/j.ahj.2012.12.002","article-title":"High mortality risks after major lower extremity amputation in Medicare patients with peripheral artery disease","volume":"165","author":"Jones","year":"2013","journal-title":"Am Heart J"},{"key":"10.1016\/j.jvs.2021.05.025_bib9","doi-asserted-by":"crossref","first-page":"1868","DOI":"10.1016\/j.jvs.2019.03.036","article-title":"Risk prediction of 30-day mortality after lower extremity major amputation","volume":"70","author":"Jolissaint","year":"2019","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2021.05.025_bib10","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1016\/j.jvs.2018.03.408","article-title":"Predictors of early mortality and readmissions among dialysis patients undergoing lower extremity amputation","volume":"68","author":"Hickson","year":"2018","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2021.05.025_bib11","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/j.avsg.2012.06.030","article-title":"A\u00a0practical index to predict 30-day mortality after major amputation","volume":"27","author":"Easterlin","year":"2013","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.jvs.2021.05.025_bib12","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.surg.2012.07.017","article-title":"Preoperative factors predict mortality after major lower-extremity amputation","volume":"152","author":"Nelson","year":"2012","journal-title":"Surgery"},{"key":"10.1016\/j.jvs.2021.05.025_bib13","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1177\/0309364615596067","article-title":"Long-term mortality after lower-limb amputation","volume":"40","author":"Singh","year":"2016","journal-title":"Prosthet Orthot Int"},{"key":"10.1016\/j.jvs.2021.05.025_bib16","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1161\/CIRCOUTCOMES.112.968826","article-title":"Consequences for healthcare quality and research of the exclusion of records from the death master file","volume":"6","author":"da Graca","year":"2013","journal-title":"Circ Cardiovasc Qual Outcomes"},{"key":"10.1016\/j.jvs.2021.05.025_bib17","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.jvs.2017.11.094","article-title":"Through-knee amputation is a feasible alternative to above-knee amputation","volume":"68","author":"Lim","year":"2018","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2021.05.025_bib18","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.avsg.2017.07.034","article-title":"Analysis of patients undergoing major lower extremity amputation in the vascular quality initiative","volume":"46","author":"Gabel","year":"2018","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.jvs.2021.05.025_bib19","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.jvs.2017.01.048","article-title":"Statin use and other factors associated with mortality after major lower extremity amputation","volume":"66","author":"DeCarlo","year":"2017","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2021.05.025_bib20","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1682\/JRRD.2014.09.0209","article-title":"Effects of prosthetic limb prescription on 3-year mortality among veterans with lower-limb amputation","volume":"52","author":"Kurichi","year":"2015","journal-title":"J\u00a0Rehabil Res Dev"},{"key":"10.1016\/j.jvs.2021.05.025_bib21","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1682\/JRRD.2014.09.0216","article-title":"Predicting prosthetic prescription after major lower-limb amputation","volume":"52","author":"Resnik","year":"2015","journal-title":"J\u00a0Rehabil Res Dev"},{"key":"10.1016\/j.jvs.2021.05.025_bib22","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1053\/apmr.2001.21856","article-title":"Rehabilitation of the geriatric vascular amputee patient: a population-based study","volume":"82","author":"Fletcher","year":"2001","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.jvs.2021.05.025_bib23","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1682\/JRRD.2012.01.0001","article-title":"Prosthetic fitting, use, and satisfaction following lower-limb amputation: a prospective study","volume":"49","author":"Webster","year":"2012","journal-title":"J\u00a0Rehabil Res Dev"},{"key":"10.1016\/j.jvs.2021.05.025_bib24","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0741-5214(03)00092-2","article-title":"Functional outcome in a contemporary series of major lower extremity amputations","volume":"38","author":"Nehler","year":"2003","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2021.05.025_bib25","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1177\/000313480206800710","article-title":"Major lower-extremity amputation: contemporary experience in a single veterans affairs institution","volume":"68","author":"Toursarkissian","year":"2002","journal-title":"Am Surg"},{"key":"10.1016\/j.jvs.2021.05.025_bib26","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.jvs.2005.04.015","article-title":"Preoperative clinical factors predict postoperative functional outcomes after major lower limb amputation: an analysis of 553 consecutive patients","volume":"42","author":"Taylor","year":"2005","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2021.05.025_bib27","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1080\/03093640008726531","article-title":"Amputees in Limburg: incidence, morbidity and mortality, prosthetic supply, care utilisation and functional level after one year","volume":"24","author":"Pernot","year":"2000","journal-title":"Prosthet Orthot Int"},{"key":"10.1016\/j.jvs.2021.05.025_bib28","doi-asserted-by":"crossref","first-page":"63","DOI":"10.3109\/03093648909078214","article-title":"Primary survival and prosthetic fitting of lower limb amputees","volume":"13","author":"Pohjolainen","year":"1989","journal-title":"Prosthet Orthot Int"},{"key":"10.1016\/j.jvs.2021.05.025_bib29","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/S0003-9993(02)04952-3","article-title":"Physical, mental, and social predictors of functional outcome in unilateral lower-limb amputees","volume":"84","author":"Schoppen","year":"2003","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.jvs.2021.05.025_bib30","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3109\/17453678308992877","article-title":"Prosthetic fitting in lower limb amputees","volume":"54","author":"Jensen","year":"1983","journal-title":"Acta Orthop Scand"},{"key":"10.1016\/j.jvs.2021.05.025_bib31","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/S1078-5884(96)80254-1","article-title":"Predicting the use of prostheses by vascular amputees","volume":"12","author":"Campbell","year":"1996","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.jvs.2021.05.025_bib32","first-page":"73","article-title":"Outcome after trans-tibial amputation for vascular disease. A follow-up after eight years","volume":"12","author":"Hermodsson","year":"1998","journal-title":"Scand J Caring Sci"},{"key":"10.1016\/j.jvs.2021.05.025_bib33","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/BF03325220","article-title":"Predictors for institutionalization and prosthetic ambulation after major lower extremity amputation during an eight-year follow-up","volume":"21","author":"Remes","year":"2009","journal-title":"Aging Clin Exp Res"},{"key":"10.1016\/j.jvs.2021.05.025_bib34","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1097\/PHM.0b013e3181cf1bee","article-title":"Outcomes of a standardized surgical and rehabilitation program in transtibial amputation for peripheral vascular disease: a prospective cohort study","volume":"89","author":"Johannesson","year":"2010","journal-title":"Am J Phys Med Rehabil"},{"key":"10.1016\/j.jvs.2021.05.025_bib35","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1093\/ptj\/67.10.1510","article-title":"Prosthetic use in elderly patients with dysvascular above-knee and through-knee amputations","volume":"67","author":"Beekman","year":"1987","journal-title":"Phys Ther"},{"key":"10.1016\/j.jvs.2021.05.025_bib36","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1111\/ggi.12016","article-title":"Rehabilitation of the older vascular amputee: a review of the literature","volume":"13","author":"Fleury","year":"2013","journal-title":"Geriatr Gerontol Int"},{"key":"10.1016\/j.jvs.2021.05.025_bib37","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.avsg.2017.05.039","article-title":"Major lower limb amputation: outcomes are improving","volume":"45","author":"Kelly","year":"2017","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.jvs.2021.05.025_bib38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jvs.2010.12.049","article-title":"Effect of gender on long-term survival after abdominal aortic aneurysm repair based on results from the Medicare national database","volume":"54","author":"Egorova","year":"2011","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2021.05.025_bib39","doi-asserted-by":"crossref","first-page":"e000386","DOI":"10.1136\/openhrt-2015-000386","article-title":"Excess short-term mortality in women after isolated coronary artery bypass graft surgery","volume":"3","author":"Filardo","year":"2016","journal-title":"Open Heart"},{"key":"10.1016\/j.jvs.2021.05.025_bib40","first-page":"3","article-title":"Sex and gender differences in clinical medicine","author":"Regitz-Zagrosek","year":"2012","journal-title":"Handb Exp Pharmacol"},{"key":"10.1016\/j.jvs.2021.05.025_bib41","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1080\/03093640802492434","article-title":"Outcomes of individuals with transfemoral and contralateral transtibial amputation due to dysvascular etiologies","volume":"33","author":"Bhangu","year":"2009","journal-title":"Prosthet Orthot Int"},{"key":"10.1016\/j.jvs.2021.05.025_bib42","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.jvs.2016.08.078","article-title":"The development and validation of the AMPREDICT model for predicting mobility outcome after dysvascular lower extremity amputation","volume":"65","author":"Czerniecki","year":"2017","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2021.05.025_bib43","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1177\/000313480607200809","article-title":"Does obesity predict functional outcome in the dysvascular amputee?","volume":"72","author":"Kalbaugh","year":"2006","journal-title":"Am Surg"},{"key":"10.1016\/j.jvs.2021.05.025_bib44","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1080\/03093640601040244","article-title":"Lower limb amputations: differences between the genders and long-term survival","volume":"31","author":"Heikkinen","year":"2007","journal-title":"Prosthet Orthot Int"},{"key":"10.1016\/j.jvs.2021.05.025_bib45","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1016\/j.apmr.2007.11.034","article-title":"Rehabilitation setting and associated mortality and medical stability among persons with amputations","volume":"89","author":"Dillingham","year":"2008","journal-title":"Arch Phys Med Rehabil"}],"container-title":["Journal of Vascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741521421008399?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741521421008399?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T20:35:39Z","timestamp":1760042139000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0741521421008399"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":43,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["S0741521421008399"],"URL":"https:\/\/doi.org\/10.1016\/j.jvs.2021.05.025","relation":{},"ISSN":["0741-5214"],"issn-type":[{"value":"0741-5214","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sex, age, and other barriers for prosthetic referral following amputation and the impact on survival","name":"articletitle","label":"Article Title"},{"value":"Journal of Vascular Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jvs.2021.05.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 by the Society for Vascular Surgery. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}